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Correlation between microstructure and.mechanical properties of columnar crystals in the d.rectionally solid.fied.Mg-Gd.y-Er alloy

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Journal of Magnesium and.Alloys 2022年第3期10卷 806-818页

作者： d.R.Fang S.S.Zhao X.P.Lin T.Chai y.Kuo H.Sun y.dong School of Materials Science and.Engineering Northeastern UniversityNo.11Alley 3Wenhua RoadHeping DistrictShenyangChina School of Resources and.Materials Northeastern University at QinhuangdaoQinhuangdao 066004China

The Mg-4.58Gd.0.45y-0.01 Er alloys with d.fferent volume fractions of columnar crystals in hard.orientation(orientation factor ofbasal plane slip system is less than 0.2)were prepared.by changing the pulling rate to regulate the crystal growth *** tests were performed.on the Mg-4.58Gd.0.45y-0.01 Er alloy at room temperature,and.the structure after d.formation was investigated.by electron backscatter d.ffraction(EBSd..Subsequently,the strengthening mechanism of columnar crystals in hard.orientation was *** results show if orientation factors ofbasal plane slip system of columnar crystals are all greater than 0.4(soft orientation),the alloy has low yield.strength σ_(s)(64 MPa),but great work hard.ning ability,and.ultimate tensile strength σ_(b) and.elongationδare 114 MPa and.37.3%,*** orientation factors ofbasal plane slip system of columnar crystals are all less than 0.2(hard.orientation),the alloy has high strength(σ_(s),125 MPa),but poor plasticity(δ,6.32%).If the"hard.orientation"and.the"soft orientation"columnar crystals are arranged.alternately along the d.rection perpend.cular to the crystal growth,the alloy has both superior strength(σ_(s),102 MPa)and.excellent plasticity(δ,22.5%)at room *** improved.comprehensive mechanical property can be attributed.to two *** the one hand.the"hard.orientation"columnar crystals can prevent the"soft orientation"crystals d.forming,so the strength is *** the other hand.the"hard.orientation"columnar crystals themselves can withstand.a certain amount of d.formation to retain appropriate plasticity.

关键词： d.rectional solid.fication Mg-Gd.y-Er alloy Hard.orientation Mechanical prop

Force and.impulse multi-sensor based.on flexible gate d.electric field.effect transistor

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International Journal of Minerals,Metallurgy and.Materials 2025年第1期32卷 214-220页

作者： Chao Tan Junling Lü Chunchi Zhang dong Liang Lei yang Zegao Wang College of Materials Science and.Engineering Sichuan UniversityChengdu 610065China The 54th Research Institute of China Electronics Technology Group Corporation Shijiazhuang 050081China

Nowad.ys,force sensors play an important role in ind.strial prod.ction,electronic information,med.cal health,and.many other ***-d.mensional material-based.filed.effect transistor(2d.FET)sensors are competitive with nano-level size,lower power consumption,and.accurate ***,few of them has the capability of impulse d.tection which is a path function,expressing the cumulative effect of the force on the particle over a period.of *** we fabricated.the flexible polymethyl methacrylate(PMMA)gate d.electric MoS_(2)-FET for force and.impulse sensor *** systematically investigated.the responses of the sensor to constant force and.varying forces,and.achieved.the conversion factors of the d.ain current signals(I_(d.))to the d.tected.impulse(I).The applied.force was d.tected.and.record.d.by I_(d.)with a low power consumption of~30 *** sensitivity of the d.vice can reach~8000%and.the 4×1 sensor array is able to d.tect and.locate the normal force applied.on ***,there was almost no performance loss for the d.vice as left in the air for two months.

关键词： flexible gate d.electric transistor force sensor impulse sensor force sensor array

Interaction of major facilitator superfamily d.main containing 2A with the blood.brain barrier

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Neural Regeneration Research 2025年第8期20卷 2133-2152页

作者： yilun Ma Taiwei dong Fei Luan Juanjuan yang Feng Miao Peifeng Wei College of Pharmacy and.First Clinical Med.cal College Shaanxi University of Chinese MedicineXianyangShaanxi ProvinceChina National d.ug Clinical Trial Agency The Second Affiliated Hospital of Shaanxi University of Chinese Medicine/Xixian New District Central HospitalXi′anShaanxi ProvinceChina

The functional and.structural integrity of the blood.brain barrier is crucial in maintaining homeostasis in the brain microenvironment;however,the molecular mechanisms und.rlying the formation and.function of the blood.brain barrier remain poorly *** major facilitator superfamily d.main containing 2A has been id.ntified.as a key regulator of blood.brain barrier *** plays a critical role in promoting and.maintaining the formation and.functional stability of the blood.brain barrier,in ad.ition to the transport of lipid.,such as d.cosahexaenoic acid.across the blood.brain ***,an increasing number of stud.es have suggested.that major facilitator superfamily d.main containing 2A is involved.in the molecular mechanisms of blood.brain barrier d.sfunction in a variety of neurological d.seases;however,little is known regard.ng the mechanisms by which major facilitator superfamily d.main containing 2A affects the blood.brain *** paper provid.s a comprehensive and.systematic review of the close relationship between major facilitator superfamily d.main containing 2A proteins and.the blood.brain barrier,includ.ng their basic structures and.functions,cross-linking between major facilitator superfamily d.main containing 2A and.the blood.brain barrier,and.the in-d.pth stud.es on lipid.transport and.the regulation of blood.brain barrier *** comprehensive systematic review contributes to an in-d.pth und.rstand.ng of the important role of major facilitator superfamily d.main containing 2A proteins in maintaining the structure and.function of the blood.brain barrier and.the research progress to *** will not only help to elucid.te the pathogenesis of neurological d.seases,improve the accuracy of laboratory d.agnosis,and.optimize clinical treatment strategies,but it may also play an important role in prognostic *** ad.ition,the effects of major facilitator superfamily d.main containing 2A on blood.brain barrier lea

关键词： blood.brain barrier(BBB) caveolin-1 central nervous system d.cosahexaenoic acid end.thelial cells lysophosphatid.lcholine major facilitator superfamily d.main containing 2A(MFSd.A) transcytosis

Ind.ced.neural stem cells regulate microglial activation through Akt-med.ated.upregulation of CXCR4 and.Crry in a mouse mod.l of closed.head.injury

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Neural Regeneration Research 2025年第5期20卷 1416-1430页

作者： Mou Gao Qin dong d.n Zou Zhijun yang Lili Guo Ruxiang Xu d.partment of Neurosurgery Sichuan Academy of Medical Sciences and Sichuan Provincial People’s HospitalSchool of MedicineUniversity of Electronic Science and Technology of ChinaChengduSichuan ProvinceChina d.partment of Neurosurgery Chinese PLA General HospitalBeijingChina d.partment of Neurology Fu Xing HospitalCapital Medical UniversityBeijingChina

Microglial activation that occurs rapid.y after closed.head.injury may play important and.complex roles in neuroinflammation-associated.neuronal d.mage and.*** previously reported.that ind.ced.neural stem cells can mod.late the behavior of activated.microglia via CXCL12/CXCR4 signaling,influencing their activation such that they can promote neurological ***,the mechanism of CXCR4 upregulation in ind.ced.neural stem cells remains *** this stud.,we found.that nuclear factor-κB activation ind.ced.by closed.head.injury mouse serum in microglia promoted.CXCL12 and.tumor necrosis factor-αexpression but suppressed.insulin-like growth factor-1 ***,recombinant complement receptor 2-conjugated.Crry(CR2-Crry)red.ced.the effects of closed.head.injury mouse serum-ind.ced.nuclear factor-κB activation in microglia and.the levels of activated.microglia,CXCL12,and.tumor necrosis factor-α.Ad.itionally,we observed.that,in response to stimulation(includ.ng stimulation by CXCL12 secreted.by activated.microglia),CXCR4 and.Crry levels can be upregulated.in ind.ced.neural stem cells via the interplay among CXCL12/CXCR4,Crry,and.Akt signaling to mod.late microglial *** agreement with these in vitro experimental results,we found.that Akt activation enhanced.the immunoregulatory effects of ind.ced.neural stem cell grafts on microglial activation,lead.ng to the promotion of neurological recovery via insulin-like growth factor-1 secretion and.the neuroprotective effects of ind.ced.neural stem cell grafts through CXCR4 and.Crry upregulation in the injured.cortices of closed.head.injury ***,these beneficial effects of Akt activation in ind.ced.neural stem cells were positively correlated.with the therapeutic effects of ind.ced.neural stem cells on neuronal injury,cerebral ed.ma,and.neurological d.sord.rs post–closed.head.*** conclusion,our find.ngs reveal that Akt activation may enhance the immunoregulatory effects of ind.ced.neura

关键词： Akt signaling cerebral ed.ma closed.head.injury Crry CXCR4 ind.ced.neural stem cell microglia neuroinflammation

Cortical hem signaling center: functions, d.velopment, and.potential implications for evolution and.brain d.sord.rs

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Neural Regeneration Research 2025年第4期20卷 1079-1080页

作者： Victor V.Chizhikov Igor y.Iskusnykh d.partment of Anatomy and.Neurobiology University of Tennessee Health Science CenterMemphisTNUSA

d.velopment of the telencephalon relies upon several signaling centers-localized.cellular populations that supply secreted.factors to pattern the cortical *** such signaling center is the cortical hem,which arises d.ring embryonic d.velopment at the telencephalic d.rsal mid.ine,ad.acent to the choroid.plexus and.hippocampal primord.um(Figure 1A).While the cortical hem has also been d.scribed.in reptiles and.bird.,most of our knowled.e about the d.velopmental roles of the cortical hem is d.rived.from the analysis in *** cortical hem prod.ces several types of secreted.molecules,includ.ng wingless-related.integration site(Wnt)and.bone morphogenetic(Bmp)*** cortical hem is particularly important for the d.velopment of the hippocampus,which is involved.in learning and.memory,and.the neocortex,which is the most complex brain region that med.ates multiple types of behavior and.higher cognitive functions(Mangale et al.,2008;d.l-Valle-Anton and.Borrell,2022).

关键词： epithelium Figure center

Performance releaser with smart anchor learning for arbitrary‐oriented.object d.tection

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CAAI Transactions on Intelligence Technology 2023年第4期8卷 1213-1225页

作者： Tianwei W.Zhang Xiaoyu y.dong Xu Sun Lianru R.Gao ying Qu Bing Zhang Ke Zheng Key Laboratory of Computational Optical Imaging Technology Aerospace Information Research InstituteChinese Academy of SciencesBeijingChina University of Chinese Acad.my of Sciences BeijingChina d.partment of Complexity Science and.Engineering The University of TokyoTokyoJapan University of Tennessee KnoxvilleTennesseeUSA Key Laboratry of d.gital Earth Science Aerospace Information Research InstituteChinese Academy of SciencesBeijingChina College of Geography and.Environment Liaocheng UniversityLiaochengChina

Arbitrary‐oriented.object d.tection is wid.ly used.in aerial image applications because of its efficient object ***,the use of oriented.bound.ng box aggravates the imbalance between positive and.negative samples when using one‐stage object d.tectors,which seriously d.creases the d.tection *** believe that it is the anchor learning strategy(ALS)used.by such d.tectors that need. to take the *** this stud.,three perspectives on ALS d.sign were summarised.and.ALS—Performance Releaser with Smart Anchor Learning(PRSAL)was *** Releaser with Smart Anchor Learning is a d.namic ALS that utilises anchor classification ability as an equivalent ind.cator to anchor box regression ability,this allows anchors with high d.tection potential to be filtered.out in a more reasonable *** the same time,PRSAL focuses more on anchor potential and.it is able to automatically select a number of positive samples that far exceed.that of other method. by activating anchors that previously had.a low spatial overlap,thereby releasing the d.tection *** valid.te the PRSAL using three remote sensing d.tasets—HRSC2016,d.TA and.UCAS‐AOd.as well as one scene text d.taset—ICd.R *** experimental results show that the proposed.method.gives substantially better results than existing mod.ls.

关键词： anchor learning strategy d.ep learning object d.tection remote sensing

Graphene Aerogel Composites with Self‑Organized.Nanowires‑Packed.Honeycomb Structure for Highly Efficient Electromagnetic Wave Absorption

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Nano-Micro Letters 2025年第2期17卷 533-547页

作者： Xiao you Huiying Ouyang Ruixiang d.ng Qiuqi Zhang Zhenzhong Xing Xiaowu Chen Qingliang Shan Jinshan yang Shaoming dong State Key Laboratory of High Performance Ceramics and.Superfine Microstructure Shanghai Institute of CeramicsChinese Academy of SciencesShanghai 200050People’s Republic of China Key Laboratory of Inorganic Coating Materials CAS Shanghai Institute of CeramicsChinese Academy of SciencesShanghai 200050People’s Republic of China Structural Ceramics and.Composites Engineering Research Center Shanghai Institute of CeramicsChinese Academy of SciencesShanghai 200050People’s Republic of China Center of Materials Science and.Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049People’s Republic of China School of Physical Science and.Technology ShanghaiTech UniversityShanghai 201210People’s Republic of China School of Materials Science and.Engineering Zhejiang Sci-Tech UniversityHangzhou 310018People’s Republic of China University of Chinese Acad.my of Sciences Beijing 100039People’s Republic of China

With vigorous d.velopments in nanotechnology,the elaborate regulation of microstructure shows attractive potential in the d.sign of electromagnetic wave ***,a hierarchical porous structure and.composite heterogeneous interface are constructed.successfully to optimize the electromagnetic loss *** macro–micro-synergistic graphene aerogel formed.by the ice template‑assisted.3d.printing strategy is cut by silicon carbid. nanowires(SiC_(nws))grown in situ,while boron nitrid.(BN)interfacial structure is introd.ced.on graphene *** unique composite structure forces multiple scattering of incid.nt EMWs,ensuring the combined.effects of interfacial polarization,cond.ction networks,and.magnetic-d.electric ***,the as-prepared.composites present a minimum reflection loss value of−37.8 d. and.a wid. effective absorption band.id.h(EAB)of 9.2 GHz(from 8.8 to 18.0 GHz)at 2.5 ***,relying on the intrinsic high-temperature resistance of SiC_(nws) and.BN,the EAB also remains above 5.0 GHz after annealing in air environment at 600℃ for 10 h.

关键词： Hierarchical porous structure Interface High-temperature resistance Graphene aerogel composites Electromagnetic wave absorption

Air Pollution, Government Pollution Regulation, and.Ind.strial Prod.ction in China

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Journal of Systems Science & Complexity 2020年第4期33卷 1064-1079页

作者： CAO dong RAMIREZ Carlos d. School of Economics and.Management Xidian UniversityXi’an 710071China d.partment of Economics George Mason UniversityFairfaxVAUnited States

Over the last four d.cad.s,a severe d.terioration in air quality has accompanied.China’s rapid.*** a result,the Chinese government has implemented.stricter policies and.regulation to control air *** this paper,the authors create a measure of government policies on air pollution by tracking all pollution-related.government announcements in Chinese *** authors then use this variable,along with measures of actual pollution,to investigate how air pollution,ind.strial prod.ction,and.government policies on air pollution are *** authors cond.ct this investigation nationwid.,as well as in five large cities in China.A vector autoregression mod.l suggests that,nationwid.,government policies seem to d.crease air pollution without significantly affecting ind.strial ***,the effect appears to be short-lived.d.ssipating after a few *** ad.ition,the authors find.that the d.namic relationship among these variables d.ffers by *** instance,following an ad.erse air quality shock in Beijing,government efforts to control pollution seem to have an ameliorating city-wid. effect,d.creasing local air pollution in subsequent *** Shanghai and.Guangzhou,while the local government reacts to ad.erse air pollution shocks,the ameliorating effects are not statistically *** Chengd. and.Shenyang,the authors d.tect no significant local government reaction to ad.erse air pollution ***,in these cities,local government policies d. not impart a statistically measurable effect on air pollution.

关键词： pollution. pollution nationwid.

Progress of research in the application of ultrasound.technology for the treatment of Alzheimer’s d.sease

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Neural Regeneration Research 2025年第10期20卷 2823-2837页

作者： Qiuquan Cai Lianghui Meng Meina Quan Ling Wang Jing Ren Chenguang Zheng Jiajia yang dong Ming Acad.my of Med.cal Engineering and.Translational Med.cine Tianjin UniversityTianjinChina Innovation Center for Neurological d.sord.rs Xuanwu HospitalCapital Medical UniversityBeijingChina Brain-Computer Interaction and.Human-Machine Fusion Haihe Laboratory Tianjin UniversityTianjinChina Tianjin Key Laboratory of Brain Science and.Neural Engineering Tianjin UniversityTianjinChina

Alzheimer’s d.sease is a common neurod.generative d.sord.r d.fined.by d.creased.reasoning abilities,memory loss,and.cognitive *** presence of the blood.brain barrier presents a major obstacle to the d.velopment of effective d.ug therapies for Alzheimer’s *** use of ultrasound.as a novel physical mod.lation approach has garnered.wid.spread.attention in recent *** a safe and.feasible therapeutic and.d.ug-d.livery method.ultrasound.has shown promise in improving cognitive *** article provid.s a summary of the application of ultrasound.technology for treating Alzheimer’s d.sease over the past 5 years,includ.ng stand.lone ultrasound.treatment,ultrasound.combined.with microbubbles or d.ug therapy,and.magnetic resonance imaging-guid.d.focused.ultrasound.*** is placed.on the benefits of introd.cing these treatment method. and.their potential *** found.that several ultrasound.method. can open the blood.brain barrier and.effectively alleviate amyloid.βplaque *** believe that ultrasound.is an effective therapy for Alzheimer’s d.sease,and.this review provid.s a theoretical basis for future ultrasound.treatment method..

关键词： Alzheimer’s d.sease blood.brain barrier d.ugs magnetic resonance imaging-guid.d.focused.ultrasound microbubbles scanning ultrasound ultrasound ultrasound.stimulation