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Iterative computational approach to the s.lution of the Hamilton-Jacobi-Bellman-ls.acs.equation in nonlinear optimal control

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Control Theory and.Technology 2018年第1期16卷 38-48页

作者： M. d. s. ALIYU d.partment of Electrical Engineering King Faisal University AI-Ahsa 31982 Saudi Arabia

In this.paper, iterative or s.cces.ive approximation method. for the Hamilton-Jacobi-Bellman-ls.acs.equations.（HJBIEs. aris.ng in both d.terminis.ic and.s.ochas.ic optimal control for affine nonlinear s.s.ems.are d.veloped. Convergence of the method. are es.ablis.ed.und.r fairly mild.as.umptions. and.examples.are s.lved.to d.mons.rate the effectivenes. of the method.. However, the res.lts.pres.nted.in the paper are preliminary, and.d. not yet imply in anyway that the s.lutions.computed.will be s.abilizing. More improvements.and.experimentation will be required.before a s.tis.actory algorithm is.d.veloped.

关键词： Hamilton-Jacobi-Bellman-ls.ac equation vector id.ntity fixed.point theory s.cces.ive approximation method.bound.d.continuous.functions convergence Riccati equation

Bod. Contour in the Pos.-Bariatric Male Patient

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Mod.rn Plas.ic s.rgery 2024年第2期14卷 15-22页

作者： Erick Zúñiga-Garza Is.ael s.lgad.-Ad.me Claud.o d. Rojas.Gutiérrez Laura María Rod.íguez-Barrios.Guillermo Álvarez-s.nchez Ed.ard. Camacho-Quintero d.partment of Plas.ic s.rgery National Medical Center &#822020 de Noviembre&#8221 Mexico City Mexico

Background. Obes.ty is.currently cons.d.red.a public health problem. Bariatric proced.res.have become an important part of obes.ty management and. cons.quently, the number of male patients.s.eking pos.-bariatric recons.ructive proced.res.have increas.d. Therefore, the clinical approach and.und.rs.and.ng of the bod. contour of this.population have become more relevant. The goal of pos.-bariatric recons.ruction is.to enhance the male s.lhouette through removal of s.in and.ad.pos. tis.ue exces., and.abd.minal rectus.d.as.as.s.repair. Material and.Method.: We cond.cted.a retros.ective s.ud. at the Plas.ic and.Recons.ructive s.rgery d.partment of the National Med.cal Center “20 d. Noviembre”. All male patients.referred.to our d.partment to s.art a pos.-bariatric recons.ruction protocol from January 2018 to d.cember 2022 were includ.d.in this.s.ud.. Res.lts. In total, 15 patients.who und.rwent corporal contouring proced.res.were includ.d.med.an age was.49.2 years.with minimum of 33 years. and.a maximum of 57 years. Med.an Bod. mas. ind.x was.28.4 kg/ms.p>2s.p> with minimum of 22 kg/ms.p>2s.p> and.maximum of 38 kg/ms.p>2s.p>. All patients.were treated.18 months.after their bariatric s.rgery. All patients.und.rwent an abd.minoplas.y as.a bod. contouring proced.re. 4 (26.7%) patients.pres.nted.complications.related.to the s.rgery. Conclus.on: We d.s.ribed.a comprehens.ve and.s.s.ematic approach to mas.ive weight los. for male patients. s.gges.ing an abd.minal marking bas.d.on the patient’s.clinical features.and.the expected.res.lts.avoid.ng feminization of the abd.minal bod. contour.

关键词： Mas.ive Weight Los. Pos.-Bariatric Male Abd.minoplas.y Contouring

Behavior of fluxed.lime iron oxid. pellets.in hot metal bath d.ring melting and.refining

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International Journal of Minerals.Metallurgy and.Materials 2013年第4期20卷 329-337页

作者： J. Pal s. Ghorai M. C. Gos.ami d. Ghos. d. Band.opad.yay s. Ghos. Cs.R-National Metallurgical Laboratory d.partment of Metallurgical and.Material Engineering Jadavpur University

Lump lime as.a fiux material in a bas.c oxygen furnace （BOF） often creates.problems.in operation d.e to its.high melting point, poor d.s.olution property, hygros.opic nature, and.fines.generation tend.ncy. To alleviate thes. problems. fluxed.lime iron oxid. pellets.（FLIP） containing 30% CaO were d.veloped.in this.s.ud. us.ng was.e iron oxid. fines.and.lime. The s.itable hand.ing s.rengths.of the pellet （crus.ing s.rength： 300 N; d.op s.rength： 130 times. of FLIP were d.veloped.by treating with CO2 or ind.s.rial was.e gas.at room temperature, while no s.parate bind.rs.were us.d. When the pellet was.ad.ed.into hot metal bath （carbon-containing molten iron）, it was.d.compos.d. melted. and.trans.ormed.to prod.ce low melting oxid.zing s.ag, becaus. it is.a combination of main CaO and.Fe2O3. This.s.ag is.s.itable for facilitating P and.C removal in refining. Furthermore, the pellet enhances.was.e utilization and.us. of CO2 in was.e gas. In this.article, emphas.s.is.given on s.ud.ing the behavior of thes. pellets.in hot metal bath d.ring melting and.refining along with thermod.namics.and.kinetics.analys.s. The obs.rved.behaviors.of the pellet in hot metal bath confirm that it is.s.itable and.beneficial for us. in BOF and.replaces.lump lime.

关键词： ore pellets lime d.s.olution melting refining bas.c oxygen converters

Further inves.igation on the fus.on of ^(6)Li with ^(209)Bi target at near-barrier energies

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Chines. Phys.cs.C 2024年第7期48卷 106-117页

作者：张高龙焦振威张广鑫 M.R.Cortes.胡世鹏钱建强 d.Mengoni 屈卫卫李聪博郑云张焕乔孙慧斌王楠张春雷 J.J.Valiente-d.bón d.Tes.ov M.Mazzocco A.Gozzelino C.Paras.and.lo d.Pierrouts.kou M.La Commara A.Goas.0}ff d.Bazzacco d.R.Napoli F.Galtaros.a F.Recchia A.Illana s.Bakes.I.Zanon s.Ayd.n G.d. Angelis.M.s.ciliano R.Menegazzo s.M.Lenzi J.L.Ferreira J.Rangel s.rkan Akkoyun L.F.Canto J.Lubian s.hool of Phys.cs Beihang UniversityBeijing 100191China s.no-French Ins.itute of Nuclear Engineering and.Technology Sun Yat-Sen UniversityZhuhai 519082China Ins.ituto d. Fís.ca Universidade Federal Fluminense24210-340NiteróiRio de JaneiroBrazil Ins.itute for Ad.anced.s.ud. in Nuclear Energy&s.fety Shenzhen UniversityShenzhen 518060China s.enzhen Key Laboratory of Res.arch and.Manufacture of High Purity Germanium Materials.and.Fetectors Shenzhen UniversityShenzhen 518060China INFN Sezione di PadovaPadovaItaly d.partimento d. fis.ca As.ronomia d.ll'Univers.ta d. pad.va PadovaItaly s.ate Key Laboratory of Rad.ation Med.cine and.Protection School of Radiation Medicine and ProtectionSoochow UniversitySuzhou 215123China China Ins.itute of Atomic Energy Beijing 102413China The Key Laboratory of Beam Technology and.Material Mod.fication of Minis.ry of Ed.cation College of Nuclear Science and TechnologyBeijing Normal UniversityBeijing 100875China INFN Laboratori Nazionali di LegnaroI-35020 LegnaroItaly INFN Sezione di NapoliI-80126 NapoliItaly d.partimento d. Farmacia Universitàdi Napoli"Federico II"I-80131 NapoliItaly d.partment of Natural and.Mathematical s.iences Faculty of EngineeringTarsus University33480 MersinTurkiye Phys.cs.d.vis.on Argonne National LaboratoryLemont-ILUSA d.partamento d. Matemaética Física e Computaç˜ao Universidade do Estado do Rio de JaneiroFaculdade de Tecnologia27537-000ResendeRio de JaneiroBrazil d.partment of Phys.cs Sivas Cumhuriyet UniversitySivasTurkey Ins.ituto d. Fís.ca Universidade Federal do Rio de JaneiroCP 6852821941-972Rio de JaneiroBrazil

The complete and.incomplete fus.on cros. s.ctions.for ^(6)Li+^(209)Bi were meas.red.us.ng the in-beamγ-ray method.around.the Coulomb *** cros. s.ctions.of(d.uteron captured.incomplete fus.on(ICF)prod.cts.were re-quantified.experimentally for this.reaction *** res.lts.reveal that the ICF cros. s.ction is.equivalent to that of complete fus.on(CF)above the Coulomb barrier and.d.minant near or below the Coulomb barrier.A theoretical calculation bas.d.on the continuum d.s.retized.coupled.channel(Cd.C)method.was.performed.for the aforementioned.CF and.ICF cros. s.ctions.the res.lt is.cons.s.ent with the *** univers.l fus.on function(UFF)was.als. compared.with the meas.red.CF cros. s.ction for d.fferent barrier parameters.d.mons.rating that the CF s.ppres.ion factor is.s.gnificantly influenced.by the choice of potential,which can reflect both d.namic and.s.atic effects.of breakup on the fus.on proces..

关键词： cros. s.ction incomplete fus.on s.ppres.ion factor weakly bound.nuclei

Therapeutic ad.ances.in neural regeneration for Huntington’s.d.s.as.

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Neural Regeneration Res.arch 2024年第9期19卷 1991-1997页

作者： Frances.o d.Egid.o Vanes.a Cas.elli Giorgia Lombard.zzi Fabrizio Ammannito Annamaria Cimini Michele d.Angelo d.partment of Life Health and Environmental SciencesUniversity of L’AquilaL’AquilaItaly

Huntington’s.d.s.as. is.a neurod.generative d.s.as. caus.d.by the expans.on mutation of a cytos.ne-ad.nine-guanine triplet in the exon 1 of the HTT gene which is.res.ons.ble for the prod.ction of the huntingtin (Htt) protein. In phys.ological cond.tions. Htt is.involved.in many cellular proces.es.s.ch as.cell s.gnaling, trans.riptional regulation, energy metabolis. regulation, d.A maintenance, axonal trafficking, and.antiapoptotic activity. When the genetic alteration is.pres.nt, the prod.ction of a mutant vers.on of Htt (mHtt) occurs. which is.characterized.by a plethora of pathogenic activities.that, finally, lead.to cell d.ath. Among all the cells.in which mHtt exerts.its.d.ngerous.activity, the GABAergic Med.um s.iny Neurons.s.em to be the mos. affected.by the mHtt-ind.ced.excitotoxicity both in the cortex and.in the s.riatum. However, as.the neurod.generation proceed. ahead.the neuronal los. grows.als. in other brain areas.s.ch as.the cerebellum, hypothalamus. thalamus. s.bthalamic nucleus. globus.pallid.s. and.s.bs.antia nigra, d.termining the variety of s.mptoms.that characterize Huntington’s.d.s.as.. From a clinical point of view, Huntington’s.d.s.as. is.characterized.by a wid. s.ectrum of s.mptoms.s.anning from motor impairment to cognitive d.s.rd.rs.and.d.mentia. Huntington’s.d.s.as. s.ows.a prevalence of around.3.92 cas.s.every 100,000 world.id. and.an incid.nce of 0.48 new cas.s.every 100,000/year. To d.te, there is.no available cure for Huntington’s.d.s.as.. s.veral treatments.have been d.veloped.s. far, aiming to red.ce the s.verity of one or more s.mptoms.to s.ow d.wn the inexorable d.cline caus.d.by the d.s.as.. In this.context, the s.arch for reliable s.rategies.to target the d.fferent as.ects.of Huntington’s.d.s.as. become of the utmos. interes.. In recent years. a variety of s.ud.es.d.mons.rated.the d.trimental role of neuronal los. in Huntington’s.d.s.as. cond.tion highlighting how the replacement of los. cells.would.be a reas.nable s.rategy to o

关键词： cell therapy exos.mes extracellular ves.cles Huntingtin Huntington’s.d.s.as. med.um s.iny neurons neurod.generative d.s.as. neurogenes.s neuronal los. s.em cells

Is.lated.traumatic orbital floor fracture:An analys.s.of the National Trauma d.ta Bank

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World.Journal of Otorhinolaryngology-Head.and.Neck s.rgery 2024年第3期10卷 187-192页

作者： Emma d. Ravin d.Katherine Xu Chris.ian Fritz Harman s.Parhar Karthik Rajas.karan d.partment of Otorhinolaryngology Head.and.Neck s.rgery University of PennsylvaniaPhiladelphiaPennsylvaniaUSA Perelman s.hool of Med.cine at the Univers.ty of Penns.lvania PhiladelphiaPennsylvaniaUSA Leonard.d.vis.Ins.itute of Health Economics University of PennsylvaniaPhiladelphiaPennsylvaniaUSA

Objectives.To d.te,no s.ud. provid.s.a comprehens.ve analys.s.of traumatic orbital floor fractures.acros. the United.*** aimed.to characterize patient d.mographics.injury-related.variables.and.operative management in this.***:The National Trauma d.ta Bank was.queried.for open or clos.d.orbital floor fractures.from 2008 to *** d.ta were ***:Overall,148,592 orbital floor fractures.were id.ntified.with 142,577(95.9%)clos.d.and.6158(4.1%)open-type fractures.A total of 106,243(71.5%)patients.were male and.the med.an patient age was.41 *** majority of patients.79.2%)had.abbreviated.injury s.ale s.ores.of≤2,ind.cating minor/mod.rate *** mechanis. of injury(MOI)d.ffered.by gend.r,with the mos. frequent being unarmed.fights.in men(34.3%)and.falls.in women(14.0%).There were 29,600 patients.19.9%)with is.lated.orbital floor(I-OF)*** MOI mos. s.rongly as.ociated.with operative intervention of with I-OF fractures.were penetrating injuries.caus.d.by a firearm(od.s.ratio[OR]:2.91;95%confid.nce interval[CI]:1.62–5.20)and.cuttings.piercings.OR:2.17;95%CI:1.29–3.65).Conclus.on:This.large epid.miological s.ud. reveals.that orbital floor fractures.tend.to pres.nt with minor or mod.rate injuries.and.are more likely to require operative intervention in s.tting of firearm or cut/pierce injuries.

关键词： epid.miology National Trauma d.ta Bank orbital fracture ris. factors trauma

Pos.-operative protein s.pplementation following orthopaed.c s.rgery: A s.s.ematic review

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s.orts.Med.cine and.Health s.ience 2024年第1期6卷 16-24页

作者： And.ew George Brend.n M.Hold.rread.Brad.ey s.Lambert Jos.ua d.Harris.Patrick C.McCulloch Hous.on Method.s. Orthoped.cs.and.s.orts.Med.cine 6445 Main Street Suite 2300HoustonTX77030USA Hous.on Method.s. Orthoped.c Biomechanics.Res.arch Laboratory 6670 Bertner AveHoustonTX77030USA

d.creas.d.mechanical load.ng after orthopaed.c s.rgery pred.s.os.s.patients.to d.velop mus.le *** purpos. of this.review was.to as.es. whether the evid.nce s.pports.oral protein s.pplementation can help d.creas. pos.operative mus.le atrophy and.or improve patient outcomes.following orthopaed.c s.rgery.A s.s.ematic review was.cond.cted.accord.ng to the Preferred.Reporting Items.for s.s.ematic Reviews.and.MetaAnalys.s.PRIs.A).PubMed.MEd.INE),Embas.,s.opus.and.Web of s.ience were s.arched.for rand.mized.controlled.trials.that as.es.ed.protein or amino acid.s.pplementation in patients.und.rgoing orthopaed.c *** inves.igators.ind.pend.ntly cond.cted.the s.arch us.ng relevant Boolean *** outcomes.includ.d.functional or phys.ologic meas.res.of mus.le atrophy or *** s.ud.es.includ.ng 611 patients.224 males.387 females.were *** s.ud.es.evaluated.protein s.pplementation after ACL recons.ruction(ACLR),3 after total hip arthroplas.y(THA),5 after total knee arthroplas.y(TKA),and.3 after s.rgical treatment of hip *** s.pplementation s.owed.beneficial effects.acros. all types.of *** primary benefit was.a d.creas. in mus.le atrophy compared.to placebo as.meas.red.by mus.le cros. s.ctional *** authors.als. d.mons.rated.improved.functional meas.res.and.quicker achievement of rehabilitation *** s.pplementation has.beneficial effects.on mitigating mus.le atrophy in the pos.operative period.following ACLR,THA,TKA,and.s.rgical treatment of hip *** effects.often correlate with improved.functional meas.res.and.quicker achievement of rehabilitation *** res.arch is.need.d.to evaluate long-term effects.of protein s.pplementation and.to es.ablis. s.and.rd.zed.population-s.ecific regimens.that maximize treatment efficacy in the pos.operative period.

关键词： Orthopaed.c s.rgery Protein s.pplementation s.s.ematic review Mus.le atrophy

Temperature and.s.ructure meas.rements.of heavy-ion-heated.d.amond.us.ng in s.tu X-ray d.agnos.ics

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Matter and.Rad.ation at Extremes 2024年第4期9卷 80-89页

作者： J.Lutgert P.Hes.elbach M.s.horner V.Bagnoud.R.Belikov P.d.echs.l B.Heus.r O.s.umphries.P.Katrik B.Lind.vis. C.Qu R.Red.er d.Riley G.s.haumann s.s.humacher A.Taus.hwitz d.Varents.v K.Weyrich X.Yu B.Zielbauer Zs.Major P.Neumayer d.Kraus Ins.itut fur Phys.k Universitat RostockAlbert-Einstein-Str.2318059 RostockGermany Gs. Helmholtzzentrum fur s.hwerionenfors.hung Planckstr.164291 DarmstadtGermany Ins.itut für Angewand.e Phys.k Goethe-Universität Frankfurt am MainMax-von-Laue-Str.160438 Frankfurt am MainGermany Ins.itut fur Geowis.ens.haften Goethe-Universitat Frankfurt am MainAltenhoferallee 160438 Frankfurt am MainGermany Helmholtz-Zentrum d.es.0}n-Ros.end.rf Bautzner Landstr.40001328 DresdenGermany European XFEL GmbH Holzkoppel 422869 SchenefeldGermany Centre for Plas.a Phys.cs School of Mathematics and PhysicsQueen’s University BelfastUniversity RoadBelfast BT71NNUnited Kingdom Ins.itut für Kernphys.k Technische Universität DarmstadtSchlossgartenstr.964289 DarmstadtGermany s.ate Key Laboratory of Nuclear Phys.cs.and.Technology Institute of Heavy Ion PhysicsPeking UniversityBeijing 100871China Helmholtz Ins.itut Jena Frobelstieg 307743 JenaGermany

We pres.nt in s.tu meas.rements.of s.ectrally res.lved.X-ray s.attering and.X-ray d.ffraction from monocrys.alline d.amond.s.mples.heated.ith an intens. puls. of heavy *** this.way,we d.termine the s.mples.heating d.namics.and.their micros.opic and.macros.opic s.ructuralintegrity over a times.an of s.veral *** the ratio of elas.ic to inelas.ic s.attering with s.ate-of-the-art d.ns.ty functionaltheory molecular d.namics.s.mulations.allows.the inference of average temperatures.around.1300 K,in agreement with pred.ctions.froms.opping power *** s.multaneous.d.ffraction meas.rements.s.ow no hints.of any volumetric graphitization of the material,butd. ind.cate the ons.t of fracture in the d.amond.*** experiments.pave the way for future s.ud.es.at the Facility for Antiproton and.on Res.arch,where a s.bs.antially increas.d.intens.ty of the heavy ion beam will be available.

关键词： heated intens. s.ructure

Vanillylacetone attenuates.cad.ium chlorid.-ind.ced.hippocampal d.mage and.memory los. through upregulation of nuclear factor erythroid.2-related.factor 2 gene and.protein expres.ion

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Neural Regeneration Res.arch 2024年第12期19卷 2750-2759页

作者： Fahaid.H.A.L-Has.em s.lah O.Bas.ir Amal F.d.wood.Moutas.m s.Aboonq Is.aeel Bin-Jaliah Abd.laiziz M.Al-Garni Mohamed.d.Mors. d.partment of Phys.ology College of MedicineKing Khalid UniversityAbhaSaudi Arabia d.partment of Bas.c Med.cal s.iences College of MedicinePrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh 11671Saudi Arabia d.partment of Phys.ology College of MedicineTaibah UniversityAl-Madinah Al-MunawwarahSaudi Arabia d.partment of Med.cine College of MedicineKing Khalid UniversityAbhaSaudi Arabia

Memory los. and.d.mentia are major public health concerns.with a s.bs.antial economic *** s.res. has.been s.own to play a crucial role in the pathophys.ology of hippocampal d.mage-ind.ced.memory *** inves.igate whether the antioxid.nt and.anti-inflammatory compound.vanillyla cetone(zingerone) can protect agains. hippocampal d.mage and.memory los. ind.ced.by cad.ium chlorid.(Cd.l_(2)) ad.inis.ration in rats.we explo red.the potential involvement of the nuclear factor erythroid.2-related.factor 2(Nrf2) s.gnaling pathway,which is.known to mod.late oxid.tive s.res. and.*** healt hy male Wis.ar rats.were d.vid.d.into five groups.vehicle-treated.control),vanillylacetone,Cd.l_(2),vanillylacetone+ Cd.l_(2),vanillylacetone+ Cd.l_(2)+ brus.tol(a s.lective pharmacological N rf2inhibitor) *** effectively attenuated.Cd.l_(2)-ind.ced.d.mage in the d.ntal gyrus.of the hippocampus.and.improved.the memory function as.es.ed.by the Morris.Water Maze ***,vanillylacetone marked.y d.creas.d.the hippocampal tis.ue levels.of inflammatory biomarkers.interleukin-6,tumor necros.s.factor-α,intracellular cell ad.es.ve molecules. and.apoptos.s.biomarkers.Bax and.cleaved.cas.as.-3).The control and.Cd.l_(2)-treated.groups.treated.with va nillylacetone s.owed.red.ced.generation of reactive oxygen s.ecies.d.creas.d.malond.ald.hyd. levels.and.increas.d.s.peroxid. d.s.utas. and.glutathione activities.along with s.gnificant elevation of nuclear Nrf2 mRNA and.protein expres.ion in hippocampal *** the protective effects.of vanillylacetone we re s.bs.antially blocked.by the co-ad.inis.ration of brus.tol(a s.lective N rf2 inhibitor).Va nillylacetone mitigated.hippocampal d.mage and.memory los. ind.ced.by Cd.l_(2),at leas. in part, by activating the nuclear trans.ription factor ***,vanillylacetone exerted.its.potent antioxid.nt and.antiinflammatory actions.

关键词： hippocampus neuroprotective Nrf2 gene oxid.tive s.res. vanillylacetone