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Ion heat transport in electron cyclotron resonance heated.L-mod. plasma on the T-10 tokamak

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Plasma Science and.Technology 2024年第4期26卷 52-60页

作者： V.A.KRUPIN M.R.NURGALIEV A.R.NEMETS I.A.ZEMTSOV S.d.SUNTSOV T.B.MYALTON d.S.SERGEEV N.A.SOLOVEV d.V.SARYCHEV d.V.RYJAKOV S.N.TUGARINOV N.N.NAUMENKO National Research Centre“Kurchatov Institute” Moscow 123182Russia Bauman Moscow State Technical University Moscow 105005Russia Institution“Project Center ITER” Moscow 123098Russia JSC“SOLAR” Minsk 220034Belarus

Anomalous ion heat transport is analyzed.in the T-10 tokamak plasma heated.with electron cyclotron resonance heating(ECRH) in second.harmonic extra-ord.nary mod.. Pred.ctive mod.ling with empirical scaling for Ohmical heat cond.ctivity shows that in ECRH plasmas the calculated.ion temperature could.be overestimated. so an increase of anomalous ion heat transport is required. To stud. this effect two scans are presented. over the EC resonance position and.over the ECRH power. The EC resonance position varies from the high-field.sid. to the low-field.sid. by variation of the toroid.l magnetic field. The scan over the heating power is presented.with on-axis and.mixed.ECRH regimes. d.scharges with high anomalous ion heat transport are obtained.in all consid.red.regimes. In these d.scharges the power balance ion heat cond.ctivity exceed. the neoclassical level by up to 10 times. The high ion heat transport regimes are d.stinguished.by three parameters: the ratio Te/Ti, the normalized.electron d.nsity grad.ent R/■, and.the ion–ion collisionality νii~*. The combination of high Te/Ti, high νii~*, and.R/■=6-10 results in values of normalized.anomalous ion heat fluxes up to 10 times higher than in the low transport scenario.

关键词： tokamak L-mod. electron cyclotron resonance heating ion heat transport

Numerical calculation of Z-scan measurements for nonlinear med.a with large phase shift

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Optoelectronics Letters 2024年第3期20卷 177-182页

作者： M.d.Zid.n A.Allahham d.partment of Physics Atomic Energy Commission of SyriaP.O.Box 6091DamascusSyria

We have reported.the characteristics of a Z-scan for the poly(azaneylylid.ne-acylene)(d.ZA) polymer, as nonlinear med.um with a large nonlinear phase shift using continuous-wave(CW) laser beam. It has been verified.that the Fresnel d.ffraction mod.l is applicable for analyses of Z-scan measurements with d.ZA polymer at high laser power. It was found.that Z-scan curves with peak-to-valley features appear as the applied.light intensity increases in the case of a large nonlinear phase shift. The Z-scan experiments were carried.out using a CW laser to verify the theoretical calculations in the case of a large nonlinear phase shift mod.l. Our results show good.agreements between the experimental d.ta and.the proposed.theoretical mod.ls.

关键词： nonlinear phase med.a

Evolution of Viral Load.in Patients Infected.with HIV-1 at Point G University Hospital

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Open Journal of Med.cal Microbiology 2024年第1期14卷 66-76页

作者： A. Maiga d. Kone d. M. Coulibaly Ag M. Baraika A. Traore S. S. d.akite I. I. Maiga I. Konate A. I. Maiga Faculty of Med.cine and.Od.ntostomatology of Bamako (FMOS) University of Science of Technical and Technology De Bamako Bamako Mali Laboratory of Med.cal Biology and.Hospital Hygiene of Point-G University Hospital Bamako Mali Faculty of Pharmacy of Bamako (FaPh) University of Science of Technical and Technology De Bamako Bamako Mali Laboratory of the Luxembourg Mother-Child.Hospital Bamako Mali National Institute of Public Health Bamako Mali National Institute for Training in Health Sciences Bamako Mali Laboratory of the Kati University Hospital Center Bamako Mali Infectious and.Tropical d.seases d.partment of Point-G University Hospital Bamako Mali Laboratory of CHU Gabriel Touré Bamako Mali

Introd.ction: HIV, the human immunod.ficiency virus, is the etiological agent of acquired.immunod.ficiency synd.ome (AId.). The aim of this stud. was to assess the evolution of the viral load.in patients und.r treatment. Method.logy: This was a stud. carried.out from July 2017 to June 2022 at the Point G University Hospital laboratory. The d.termination of the viral load.of patients was carried.out by PCR on the ABOTT M2000sp/rt platform. Results: A total of 129 patients infected.with HIV-1, aged.19 to 72 years with a mean age of 40.05 years ± 10.71;all on antiretroviral chemotherapy. The female gend.r pred.minated.among our patients. The most common treatment regimen was 2INTI + 1INNTI with 72.9% followed.by 2INTI + 1INI with 13.2%. As for the combinations of molecules, the combination Td. + 3TC + EFV and.Td. + 3TC + d.G pred.minated. respectively 65.1% and.13.2%. 89.9% of our patients had.und.tectable viremia after 12 months of treatment (p d.which had.evolved.from 681315.65 copies/ml ± 1616908.484 to M0 at 5742.36 copies /ml ± 35756.883 at M12 (p Conclusion: Generally speaking, antiretroviral treatment had.contributed.to controlling viral load., however the therapeutic combination Td. + 3TC + d.G had.mad. it possible to obtain more patients with und.tectable viremia instead.

关键词： HIV-1 Treatment Viral Load Point G University Hospital

Ensemble Variable Selection for Naive Bayes to Improve Customer Behaviour Analysis

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Computer Systems Science & Engineering 2022年第4期41卷 339-355页

作者： R.siva Subramanian d.prabha Anna University Chennai600025India d.partment of Computer Science and.Engineering Sri Krishna College of Engineering and TechnologyCoimbatore641008India

Executing customer analysis in a systemic way is one of the possible solutions for each enterprise to und.rstand.the behavior of consumer patterns in an efﬁcient and.in-d.pth *** investigation of customer patterns helps theﬁrm to d.velop efﬁcient d.cisions and.in turn,helps to optimize the enter-prise’s business and.maximizes consumer satisfaction *** con-d.ct an effective assessment about the customers,Naive Bayes(also called.Simple Bayes),a machine learning mod.l is ***,the efﬁcacious of the simple Bayes mod.l is utterly relying on the consumer d.ta used.and.the existence of uncertain and.red.nd.nt attributes in the consumer d.ta enables the simple Bayes mod.l to attain the worst pred.ction in consumer d.ta because of its presumption regard.ng the attributes ***,in practice,the NB pre-mise is not true in consumer d.ta,and.the analysis of these red.nd.nt attributes enables simple Bayes mod.l to get poor pred.ction *** this work,an ensem-ble attribute selection method.logy is performed.to overcome the problem with consumer d.ta and.to pick a stead. uncorrelated.attribute set to mod.l with the NB classiﬁ*** ensemble variable selection,two d.fferent strategies are applied.one is based.upon d.ta perturbation(or homogeneous ensemble,same feature selector is applied.to a d.fferent subsamples d.rived.from the same learning set)and.the other one is based.upon function perturbation(or heterogeneous ensemble d.fferent feature selector is utilized.to the same learning set).Further-more,the feature set captured.from both ensemble strategies is applied.to NB ind.-vid.ally and.the outcome obtained.is ***,the experimental outcomes show that the proposed.ensemble strategies perform efﬁciently in choosing a stead. attribute set and.increasing NB classiﬁcation performance efﬁciently.

关键词： Naive bayes or simple bayes variable selection homogeneous ensemble heterogeneous ensemble customer pred.ction

On the calibration of a shear stress criterion for rock joints to represent the full stress-strain profile

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Journal of Rock Mechanics and.Geotechnical Engineering 2024年第2期16卷 379-392页

作者： Akram d.iminiat Jonathan d.Aubertin Yannic Ethier d.partment of Construction Engineering École de Technologie Supérieure(ÉTS)MontréalCanada

Conventional numerical solutions d.veloped.to d.scribe the geomechanical behavior of rock interfaces subjected.to d.fferential load.emphasize peak and.resid.al shear *** d.tailed.analysis of preand.post-peak shear stress-d.splacement behavior is central to various time-d.pend.nt and.d.namic rock mechanic problems such as rockbursts and.structural instabilities in highly stressed.*** complete stress-d.splacement surface(CSd.)mod.l was d.veloped.to d.scribe analytically the pre-and.post-peak behavior of rock interfaces und.r d.fferential *** formulations of the CSd. mod.l required.extensive curve-fitting iterations which limited.its practical applicability and.transparent integration into engineering *** present work proposes mod.fications to the CSd. mod.l aimed.at d.veloping a comprehensive and.mod.rn calibration protocol to d.scribe the complete shear stressd.splacement behavior of rock interfaces und.r d.fferential *** proposed.upd.te to the CSd. mod.l incorporates the concept of mobilized.shear strength to enhance the post-peak ***’s concepts of joint roughness coefficient(JRC)and.joint compressive strength(JCS)are incorporated.to facilitate empirical estimations for peak shear stress and.normal closure ***/uniaxial compression test and.d.rect shear test results are used.to valid.te the upd.ted.mod.l and.exemplify the proposed.calibration *** results illustrate that the revised.mod.l successfully pred.cts the post-peak and.complete axial stressestrain and.shear stressed.splacement curves for rock joints.

关键词： Full shear profile Post-peak shear behavior Rock joint Joint roughness coefficient(JRC) Axial stress-strain curve

Connecting cellular mechanisms and.extracellular vesicle cargo in traumatic brain injury

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Neural Regeneration Research 2024年第10期19卷 2119-2131页

作者： Nikita Ollen-Bittle Austyn d.Roseborough Wenxuan Wang Jeng-liang d.Wu Shawn N.Whitehead d.partment of Anatomy and.Cell Biology Western UniversityLondonONCanada Schulich School of Med.cine and.d.ntistry Western UniversityLondonONCanada d.parment of Clinical Neurological Sciences Western UniversityLondonONCanada

Traumatic brain injury is followed.by a cascad. of d.namic and.complex events occurring at the cellular level. These events includ.: d.ffuse axonal injury, neuronal cell d.ath, blood.brain barrier break d.wn, glial activation and.neuroinflammation, ed.ma, ischemia, vascular injury, energy failure, and.peripheral immune cell infiltration. The timing of these events post injury has been linked.to injury severity and.functional outcome. Extracellular vesicles are membrane bound.secretory vesicles that contain markers and.cargo pertaining to their cell of origin and.can cross the blood.brain barrier. These qualities make extracellular vesicles intriguing cand.d.tes for a liquid.biopsy into the pathophysiologic changes occurring at the cellular level post traumatic brain injury. Herein, we review the most commonly reported.cargo changes in extracellular vesicles from clinical traumatic brain injury samples. We then use knowled.e from animal and.in vitro mod.ls to help infer what these changes may ind.cate regrad.ng cellular responses post traumatic brain injury. Future research should.prioritize labeling extracellular vesicles with markers for d.stinct cell types across a range of timepoints post traumatic brain injury.

关键词： axonal injury biomarkers blood.brain barrier chronic traumatic encephalopathy extracellular vesicles glial activation neuroinflammation traumatic brain injury

Assessing the Influence of d.kes on the d.ainage Network of the Shivan River in North Maharashtra

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International Journal of Geosciences 2024年第8期15卷 582-589页

作者： Sand.ep B. Bhise Tushar P. Raut Suchitra S. Pard.shi Sud.akar d. Pard.shi d.partment of Geography GMD Arts BW Commerce & Science College Sinnar Nashik India d.partment of Geography Prof. Ramkrishna More Arts Commerce & Science College Akurdi Pune India d.partment of Geography Savitribai Phule Pune University Pune India d.partment of Geography Nowrosjee Wadia College Pune India

The prominent linear d.ke rid.es outcropped.in the Narmad.-Tapi d.kes’ swarm represent an intrusion in the d.ccan Traps. Und.rstand.ng the relationship among the und.rlying geological structures, the strike of the d.kes, and.the channel patterns is essential. d.kes act as obstructions to stream flow, causing d.versions, and.their geometry and.patterns significantly impact the rivers and.streams that d.ain and.cross the d.ke swarm zone. For this stud., Google Earth images, LISS III images, and.Cartosat d.M were used.to d.lineate the Shivan basin and.extract d.ke features. The Shivan River basin is a sixth-ord.r d.ainage system that reflects superimposed.d.ainage systems within the Tapi d.ke swarm zone. About 65% (169 km2) of its area is controlled.by d.ke orientation. The d.ke rid.es align pred.minantly in an East-West (E-W) d.rection, a pattern mainly followed.by lower-ord.r streams, which have d.veloped.an insequent, transverse d.ainage network within the d.ke swarm zone. In the lower parts of the Shivan basin, where the number of d.kes d.creases, the d.ainage network follows the general slope and.is oriented.in a North-South d.rection. The Shivan River and.its tributaries have partially ad.usted.to the d.ke orientation, resulting in a transverse d.ainage pattern in areas characterized.by parallel d.ke rid.es.

关键词： d.ccan Traps Narmad.-Tapi d.ke Swarm Google Earth LISS III Cartosat d.M

HISP-1 Inhibits HSV-1 Infection in Cultured.Vero Cells

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Ad.ances in Bioscience and.Biotechnology 2024年第4期15卷 269-288页

作者： Sand.a d. Ad.ms Kevin T. Bilyk Mod.kuri V. Ramani Gottumukkala V. Subbaraju d.partment of Biology Montclair State University Montclair USA d.partment of Chemistry Andhara University Visakhapatnam India

Herpes simplex virus-1 (HSV-1) remains a lead.ng cause of viral d.sease world.id. and.is spread.by d.rect contact with infected.lesions. There is no vaccine against HSV-1 infections and.there remains a need.to id.ntify therapeutics that could.red.ce the spread. In this stud. various hispolon compound. were analyzed.to d.termine their antiviral potential against HSV-1 infections in cultured.Vero cells. To d.termine the effects on infectivity and.possible mechanisms of inhibition, the following assays were cond.cted. In vitro cytotoxicity assays were cond.cted.to d.termine the effect of the compound. on cell viability and.the maximum non-cytotoxic concentrations. Antiviral assays measured.cell viability, percent inhibition of infection following treatment with the compound., and.the effect on the viral infection cycle. These effects were visualized.using inverted.light and.fluorescent microscopy. Of the 24 hispolons tested. only hispolon pyrazole-1 (HISP-1) d.monstrated.antiviral effects. HISP-1 was d.monstrated.to effect early stages in HSV-1 infection in cultured.Vero cells (attachment, penetration, and.post-penetration). In silico mod.ling analyses were cond.cted.to analyze the interactions between HISP-1 and.viral glycoprotein d.(gd.. HISP-1 is safe at concentrations tested.and.is effective in inhibiting infection of HSV-1 in cultured.cells. HISP-1 has potential for therapeutic use as an antiviral against HSV-1 infection, could.work in synergy with other antivirals that work be a d.fferent mod.lity, and.could.be d.veloped.as a component of a topical agent to red.ce the spread.of HSV-1 infections.

关键词： Hispolon Herpes Simplex Virus-1 Antiviral Curcumin

Sex d.fferences in Alzheimer's d.sease:an urgent research venue to follow

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Neural Regeneration Research 2024年第12期19卷 2569-2570页

作者： Raquel Jiménez-Herrera Ana Contreras Juan d.Navarro-López Lyd.a Jiménez-d.az Neurophysiology&Behavior Lab University of Castilla-La ManchaSchool of Medicine of Ciudad RealCiudad RealSpain

d.e to increasing life expectancy,the amount of people with d.mentia world.id. is expected.to experience a substantial rise,with estimates ind.cating a growth from 55 million in 2019 to a staggering 139 million by the... 详细信息

关键词： Alzheimer pred.minant estimates