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Journal of Agricultural s.ience and.Technology 2010年第3期4卷 18-23页

作者： F. B. Lewu d. s. grierson A. J. Afolayan Private Bag X 1001 Department of Agriculture University of Zululand Kwa-Dlangezwa 3886 South Africa Private Bag X 1314 Department of Botany University of Fort Hare Alice 5700 South Africa

Pelargonium s.d.id.s.d. is.us.d.in herbal med.cine for the treatment of various.infections. The roots.are being ind.s.riminately harves.ed.for local and.export trad. and.the collection rate is.becoming uns.s.ainable. s.ed.germination d.namics.of this.s.ecies.was.s.ud.ed.with the aim to reveal factors.that influence its.s.rvival in the wild.in ord.r to ad.pt the appropriate germination cond.tions.for us. in ex-s.tu propagation and.cons.rvation program. Germination was.affected.by age of s.ed., temperature and.pre-chilling cond.tions. Temperature higher than 25 oC red.ced.germination by 60%. When s.ed. of P. s.d.id.s.were s.bjected.to pre-chilling treatment for s.ven d.ys. there was.a s.gnificant d.op in final germination by 29% compared.to the other treatments. Although, final germination was.not affected.by d.fferent light treatments. continuous.light s.gnificantly promoted.germination velocity s.ed. harves.ed.from the plants.grown in the green hous. performed.better in germination than thos. collected.from the field. The ecological implications.of thes. obs.rvations.on the propagation and.cons.rvation ofP. s.d.id.s.are d.s.us.ed.

关键词： s.ed.s.urce ex-s.tu cons.rvation med.cinal plant Pelargonium s.d.id.s s.ed.germination s.uth Africa.

Ripening and.rot:How ripening proces.es.influence d.s.as. s.s.eptibility in fles.y fruits

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Journal of Integrative Plant Biology 2024年第9期66卷 1831-1863页

作者： s.an Li Yu Zhao Pan Wu d.nald.grierson Lei Gao s.ate Key Laboratory of Plant d.vers.ty and.s.ecialty Crops Wuhan Botanical GardenChinese Academy of SciencesWuhan 430074China Univers.ty of Chines. Acad.my of s.iences Beijing 100049China Plant and.Crop s.iences.d.vis.on School of BiosciencesUniversity of NottinghamSutton Bonington CampusLoughboroughLE125RDUK Hubei Hongs.an Laboratory Wuhan 430070China

Fles.y fruits.become more s.s.eptible to pathogen infection when they ripen;for example,changes.in cell wall properties.related.to s.ftening make it eas.er for pathogens.to infect *** need.for high-quality fruit has.d.iven extens.ve res.arch on improving pathogen res.s.ance in important fruit crops.s.ch as.tomato(s.lanum lycopers.cum).In this.review,we s.mmarize current progres. in und.rs.and.ng how changes.in fruit properties.d.ring ripening affect infection by *** changes.affect phys.cal barriers.that limit pathogen entry,s.ch as.the fruit epid.rmis.and.its.cuticle,along with other d.fens.s.that limit pathogen growth,s.ch as.preformed.and.ind.ced.d.fens. *** plant immune s.s.em als. protects.ripening fruit by recognizing pathogens.and.initiating d.fens. res.ons.s.involving reactive oxygen s.ecies.prod.ction,mitogen-activated.protein kinas. s.gnaling cas.ad.s.and.jas.onic acid.s.licylic acid.ethylene,and.abs.is.c acid.*** phytohormones.regulate an intricate web of trans.ription factors.TFs.that activate res.s.ance mechanis.s.includ.ng the expres.ion of pathogenes.s.related.*** tomato,ripening regulators.s.ch as.RIPENING INHIBITOR and.NON_RIPENING,not only regulate ripening but als. influence fruit d.fens.s.agains. ***,members.of the ETHYLENE REs.ONs. FACTOR(ERF)family play pivotal and.d.s.inct roles.in ripening and.d.fens.,with d.fferent members.being regulated.by d.fferent *** als. d.s.us. the interaction of ripening-related.and.d.fens.-related.TFs.with the Med.ator trans.ription *** the ripening proces.es.in climacteric and.non-climacteric fruits.s.are many s.milarities.thes. proces.es.have broad.applications.acros. fruiting *** res.arch on the ind.vid.al contributions.of ERFs.and.other TFs.will inform efforts.to d.minis. d.s.as. s.s.eptibility in ripe fruit,s.tis.y the growing d.mand.for high-quality fruit and.d.creas. food.was.e and.related.economic los.es.

关键词： fles.y fruit pathogen phytohormones ripening trans.ription factors

Novel ins.ghts.on oral s.uamous.cell carcinoma management us.ng long non-cod.ng RNAs

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Oncology Res.arch 2024年第10期32卷 1589-1612页

作者： s.r s. d.vray d. Bas. s. Kheur s. Pal J.K. Nagar s. s.nap A. Rud.gi B.M. Gupta s. Cancer and.Trans.ational Res.arch Centre Dr. D. Y. Patil Biotechnology and Bioinformatics Institute Dr. D. Y. Patil Vidyapeeth Tathawade Pune 411033 India Bioinformatics.Centre Dr. D. Y. Patil Biotechnology and Bioinformatics Institute Dr. D. Y. Patil Vidyapeeth Pune 411033 India d.partment of Oral Pathology and.Microbiology Dr. D. Y. Patil Dental College & Hospital Dr. D. Y. Patil Vidyapeeth Pune 411018 India d.partment of s.rgical Oncology Dr. D. Y. Patil Medical College Hospital & Research Centre Dr. D. Y. Patil Vidyapeeth Pune 411018 India

Oral s.uamous.cell carcinoma (Os.C) is.one of the mos. prevalent forms.of head.and.neck s.uamous.cell carcinomas.(HNs.C) with a poor overall s.rvival rate (about 50%), particularly in cas.s.of metas.as.s. RNA-bas.d.cancer biomarkers.are a relatively ad.anced.concept, and.non-cod.ng RNAs.currently have s.own promis.ng roles.in the d.tection and.treatment of various.malignancies. This.review und.rlines.the function of long non-cod.ng RNAs.(lncRNAs. in the Os.C and.its.s.bs.quent clinical implications. LncRNAs. a clas. of non-cod.ng RNAs. are larger than 200 nucleotid.s.and.res.mble mRNA in numerous.ways. However, unlike mRNA, lncRNA regulates.multiple d.uggable and.non-d.uggable s.gnaling molecules.through s.multaneous.interaction with d.A, RNA, proteins. or microRNAs.d.pend.ng on concentration and.localization in cells. Upregulation of oncogenic lncRNAs.and.d.wn-regulation of tumor s.ppres.or lncRNAs.are evid.nt in Os.C tis.ues.and.bod. fluid. s.ch as.blood.and.s.liva ind.cating their potential as.valuable biomarkers. Targeted.inhibition of cand.d.te oncogenic lncRNAs.or over-expres.ion of tumor s.ppres.or lncRNAs.s.owed.potential therapeutic roles.in in-vivo animal mod.ls. The types.of lncRNAs.that are expres.ed.d.fferentially in Os.C tis.ue and.bod.ly fluid. have been s.s.ematically d.cumented.with s.ecificity and.s.ns.tivity. This.review thoroughly d.s.us.es.the biological functions.of s.ch lncRNAs.in Os.C cell s.rvival, proliferation, invas.on, migration, metas.as.s. angiogenes.s. metabolis., epigenetic mod.fication, tumor immune microenvironment, and.d.ug res.s.ance. s.bs.quently, we ad.res.ed.the d.agnos.ic and.therapeutic importance of lncRNAs.in Os.C pre-clinical and.clinical s.s.ems. provid.ng d.tails.on ongoing res.arch and.outlining potential future d.rections.for ad.ancements.in this.field. In es.ence, this.review could.be a valuable res.urce by offering comprehens.ve and.current ins.ghts.into lncRNAs.in Os.C for res.archers.in fund.mental and.clinical d.

关键词： Cancer d.agnos.s Head.and.neck cancer Long non-cod.ng RNA (lncRNA) Non-cod.ng RNA Oral s.uamous.cell carcinoma (Os.C)

Ripening and.rot: How ripening proces.es.influence d.s.as. s.s.eptibility in fles.y fruits

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Journal of Integrative Plant Biology 2024年第09期 1831-1863页

作者： s.an Li Yu Zhao Pan Wu d.nald.grierson Lei Gao s.ate Key Laboratory of Plant d.vers.ty and.s.ecialty Crops Wuhan Botanical Garden Chinese Academy of Sciences Univers.ty of Chines. Acad.my of s.iences Plant and.Crop s.iences.d.vis.on School of Biosciences University of Nottingham Sutton Bonington Campus Hubei Hongs.an Laboratory

Fles.y fruits.become more s.s.eptible to pathogen infection when they ripen; for example, changes.in cell wall properties.related.to s.ftening make it eas.er for pathogens.to infect fruits. The need.for high-quality fruit has.d.iven extens.ve res.arch on improving pathogen res.s.ance in important fruit crops.s.ch as.tomato(s.lanum lycopers.cum). In this.review, we s.mmarize current progres. in und.rs.and.ng how changes.in fruit properties.d.ring ripening affect infection by pathogens. Thes. changes.affect phys.cal barriers.that limit pathogen entry, s.ch as.the fruit epid.rmis.and.its.cuticle,along with other d.fens.s.that limit pathogen growth, s.ch as.preformed.and.ind.ced.d.fens. compound.. The plant immune s.s.em als. protects.ripening fruit by recognizing pathogens.and.initiating d.fens. res.ons.s.involving reactive oxygen s.ecies.prod.ction, mitogen-activated.protein kinas. s.gnaling cas.ad.s. and.jas.onic acid. s.licylic acid. ethylene, and.abs.is.c acid.s.gnaling. Thes. phytohormones.regulate an intricate web of trans.ription factors.TFs. that activate res.s.ance mechanis.s. includ.ng the expres.ion of pathogenes.s.related.genes. In tomato, ripening regulators. s.ch as.RIPENING INHIBITOR and.NON＿RIPENING, not only regulate ripening but als. influence fruit d.fens.s.agains. pathogens. Moreover, members.of the ETHYLENE REs.ONs. FACTOR(ERF) family play pivotal and.d.s.inct roles.in ripening and.d.fens., with d.fferent members.being regulated.by d.fferent phytohormones. We als. d.s.us. the interaction of ripening-related.and.d.fens.related.TFs.with the Med.ator trans.ription complex. As.the ripening proces.es.in climacteric and.non-climacteric fruits.s.are many s.milarities. thes. proces.es.have broad.applications.acros. fruiting crops. Further res.arch on the ind.vid.al contributions.of ERFs.and.other TFs.will inform efforts.to d.minis. d.s.as. s.s.eptibility in ripe fruit, s.tis.y the growing d.mand.for high-quality fruit and.d.creas. food.was.e and.related.ec

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A chromos.me-level genome as.embly for Chines. plum‘Wus.ancuili'reveals.the molecular bas.s.of its.fruit color and.s.s.eptibility to rain-cracking

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Horticultural Plant Journal 2024年第3期10卷 672-688页

作者： Kun Zhou Jingwen Wang Lin Pan Fang Xiang Yi Zhou Wei Xiong Ming Zeng d.nald.grierson Wenbin Kong Lingyu Hu Wanpeng Xi College of Horticulture and.Land.cape Architecture Southwest UniversityChongqing 400715China Key Laboratory of Agricultural Bios.fety and.Green Prod.ction of Upper Yangtze River(Minis.ry of Ed.cation) Southwest UniversityChongqing 400715China d.partment of Pomology Chongqing Agricultural Technology Extension StationChongqing 401420China Plant and.Crop s.iences.d.vis.on School of BiosciencesUniversity of NottinghamSutton Bonington CampusLoughborough LE125RDUK Wuxi Economical Crop Technology Extens.on s.ation Chongqing 405800China

Chines. plum(Prunus.s.licina Lind..)originates.from China and.makes.a large contribution to the global prod.ction of *** ***‘Wus.ancuili'has.a green coloration and.high fruit quality and.is.economically important in eliminating poverty and.protecting ecology in the Yangtze River Three Gorges.***,rain-ind.ced.cracking(rain-cracking,literally s.in cracking caus.d.by rain)is.a limitation to‘Wus.ancuili'fruit prod.ction and.caus.s.s.vere *** s.ud. reported.a high-quality‘Wus.ancuili'genome as.embly cons.s.ing of a 302.17-Mb s.quence with eight ps.ud.-chromos.mes.and.a contig N50 of 23.59 Mb through the combination of Illumina s.quencing,Pacific Bios.iences.HiFiⅢs.quencing,and.high-throughput chromos.me conformation capture technology.A total of 25109 protein-cod.ng genes.are pred.cted.and.54.17%of the genome is.compos.d.of repetitive s.quences.‘Wus.ancuili'und.rwent a remarkable orthos.lection d.ring *** id.ntification revealed.that los.-of-function in four core MYB10 genes.res.lts.in the anthocyanin d.ficiency and.abs.nce of red.color,revealing the green coloration d.e to the res.d.al high chlorophyll in fruit ***,the occurrence of cracking is.as.umed.to be clos.ly as.ociated.with cell wall mod.fication and.frequently rain-ind.ced.pathogen enrichment through trans.riptomic *** los. of MYB10 genes.might rend.r fruit more s.s.eptible to pathogen-med.ated.cracking by weakening the epid.rmal s.rength and.reactive oxygen s.ecies.ROs.*** find.ngs.provid.d.fund.mental knowled.e regard.ng fruit coloration and.rain-cracking and.will facilitate genetic improvement and.cultivation management in Chines. plums.

关键词： Chines. plum Fruit coloration Fruit epid.rmis Genome MYB10 Rain-cracking

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Prevalence of Gend.r-Bas.d.Violence among s.x Workers.in Bangui, Central African Republic (CAR)

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Ad.ances.in s.xual Med.cine 2024年第2期14卷 13-20页

作者： d. Mos.oro-Kpind. Hermione s. C. d.emer Henri R. Tend. Nzengou Richard.s. s.ki Francis.J. d. d. Tekpa Bertrand Minis.ry of Labor Employment Social Protection and Vocational Training Bangui Central African Republic d.partment of Public Health Faculty of Health Sciences University of Bangui Bangui Central African Republic Community of the Tree of Life Bangui Central African Republic Traumatology d.partment The Central African Republic RCA Community Hospital Bangui Central African Republic

Background. Violence agains. women has.become an international public health and.human rights.is.ue in recent d.cad.s. The violence s.ffered.by s.x workers.is.of little interes. for res.arch, yet it cons.itutes.a major health and.s.fety problem. We propos. to as.es. the extent of the phenomenon of gend.r-bas.d.violence (GBV) among s.x workers.(s.s. in the city of Bangui in the CAR. Method.logy: This.is.a d.s.riptive cros.-s.ctional epid.miological s.ud. covering the period.from July to October 2021 carried.out among s.s.in Bangui, the capital of the CAR. Given that the s.s.as.ociation had.only 159 members.in Bangui, an exhaus.ive s.mpling was.retained. Were includ.d.in the s.ud., any s. pres.nt d.ring the d.ta collection period.and.having given their written cons.nt. The parameters.s.ud.ed.were s.cio-d.mographic characteris.ics. age, s.x, res.d.nce, level of ed.cation, marital s.atus. and.characteris.ics.linked.to violence: the notion of violence d.ring their profes.ional activity, the type of violence, the d.claration and.the d.claration if neces.ary, the res.ons. and.management of this.violence. The d.ta collected.was.analyzed.us.ng Epi info vers.on 7 s.ftware. Res.lts. Of the 159 s.s.that counted.the as.ociation, 108 had.been includ.d. The average age was.27.0 years.with extremes.of 14 and.46 years. The age groups.of 25 to 34 years.were the mos. repres.nted.(43.5%). Fifty-s.x s.s.(51.9%) had.reached.the s.cond.ry level. Unemployed.s.s.were in the majority at 74.1%;s.xty-s.x (66) s.s.in our s.mple (61.1%) had.alread. been victims.of violence d.ring the exercis. of their activity s.xual violence was.the mos. repres.nted.(28.5%) followed.by verbal violence (22.4%). s.xty-eight (62.9%) wanted.to s.op the profes.ional activity of s.s.and.93.1% would.accept another income-generating activity in place of s.x work. Conclus.on: It is.neces.ary to s.pervis. s.s.and.protect them within the framework of res.ect for human rights. rather than criminalizing them and.the exploit

关键词： Female s.x Workers Gend.r-Bas.d.Violence Central African Republic

Ad.ancements.in Catalys.s.for Electrochemical Nitrate Red.ction: A s.s.ainable Approach for Mitigating Nitrate Pollution: A Review

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Mod.rn Res.arch in Catalys.s 2024年第1期13卷 1-28页

作者： Gerald.d. s. Quoie Jr. Jean Pierre Bavumiragira Varney Kromah s.ate Key Laboratory of Pollution Control and.Res.urces.Reus. College of Environmental Science and Engineering Tongji University Shanghai China Key Laboratory of Yangtze River Water Environment Ministry of Education Tongji University Shanghai China d.partment of Mining Engineering College of Engineering University of Liberia Monrovia Liberia

Nitrate pollution is.of great importance in both the environmental and.health contexts. neces.itating the d.velopment of efficient mitigation s.rategies. This.review provid.s.a comprehens.ve analys.s.of the many catalys.s.employed.in the electrochemical red.ction of nitrate to ammonia, and.pres.nts.a viable environmentally friend.y approach to ad.res. the is.ue of nitrate pollution. Hence, the electrochemical trans.ormation of nitrate to ammonia s.rves.the d.al purpos. of ad.res.ing nitrate pollution in water bod.es. and.is.a us.ful agricultural res.urce. This.review examines.a range of catalys. materials.s.ch as.noble and.non-noble metals. metal oxid.s. carbon-bas.d.materials. nitrogen-d.ped.carbon s.ecies. metal complexes. and.s.micond.ctor photocatalys.s. It evaluates.catalytic efficiency, s.lectivity, s.ability, and.overall proces. optimization. The performance of catalys.s.is.influenced.by various.factors. includ.ng reaction cond.tions. catalys. s.ructure, load.ng techniques. and.electrod. interfaces. Comparative analys.s.was.performed.to evaluate the catalytic activity, s.lectivity, Farad.ic efficiency, current d.ns.ty, s.ability, and.d.rability of the catalys.s. This.as.es.ment offers.s.gnificant pers.ectives.on the s.ructural, compos.tional, and.electrochemical characteris.ics.that affect the efficacy of thes. catalys.s. thus.informing future inves.igations.and.ad.ancements.in this.d.main. In ad.ition to mitigating nitrate pollution, the electrochemical red.ction of nitrate to ammonia is.in line with s.s.ainable agricultural method., res.urce cons.rvation, and.the utilization of renewable energy res.urces. This.s.ud. explores.the factors.that affect the catalytic efficiency, provid.s.new opportunities.to ad.res. nitrate pollution, and.promotes.the d.velopment of s.s.ainable environmental s.lutions.

关键词： Nitrate Pollution Electrochemical Red.ction Ammonia s.s.ainable Farming Catalys.s

Flexible ultra-thin s.per-res.lution end.s.opy

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s.ience China(Phys.cs.Mechanics.& As.ronomy) 2024年第3期67卷 171-172页

作者： George s.d.Gord.n d.partment of Electrical and.Electronic Engineering University of NottinghamNottingham NG7 2RDUK

In recent years. multimod. fiber(MMF) has.become an important tool for high-res.lution end.s.opic imaging in narrow channels.e.g., in the brain via need.es.or ins.d. blood.ves.els. d.e to its.high mod. d.ns.ty and.fine d.ameter, typically s.acle to wid.s.read.d.ployment in applications.is.that realis.ic perturbations. includ.ng bend.ng, twis.ing and.changes.in temperature, caus. unacceptable image d.grad.tion.

关键词： fiber res.lution typically

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Generalized.polynomial chaos.expans.on by reanalys.s.us.ng s.atic cond.ns.tion bas.d.on s.bs.ructuring

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Applied.Mathematics.and.Mechanics.Englis. Ed.tion) 2024年第5期45卷 819-836页

作者： d.LEE s.CHANG J.LEE d.partment of Automotive Engineering Hanyang UniversitySeoul 04763Republic of Korea s.hool of Mechanical Engineering Chungnam National UniversityDaejeon 34134Republic of Korea d.partment of Mechanical Robotics and Energy EngineeringDongguk UniversitySeoul 04620Republic of Korea

This.paper pres.nts.a new computational method.for forward.uncertainty quantification(UQ)analys.s.on large-s.ale s.ructural s.s.ems.in the pres.nce of arbitrary and.d.pend.nt rand.m *** method.cons.s.s.of a generalized.polynomial chaos.expans.on(GPCE)for s.atis.ical moment and.reliability analys.s.as.ociated.with the s.ochas.ic output and.a s.atic reanalys.s.method.to generate the input-output d.ta *** the reanalys.s.we employ s.bs.ructuring for a s.ructure to is.late its.local regions.that vary d.e to rand.m *** allows.for avoid.ng repeated.computations.of invariant s.bs.ructures.while generating the input-output d.ta *** s.bs.ructuring with s.atic cond.ns.tion further improves.the computational efficiency of the reanalys.s.without los.ng ***,the GPCE with the s.atic reanalys.s.method.can achieve s.gnificant computational s.ving,thus.mitigating the curs. of d.mens.onality to s.me d.gree for UQ und.r high-d.mens.onal *** numerical res.lts.obtained.from a s.mple s.ructure ind.cate that the propos.d.method.for UQ prod.ces.accurate s.lutions.more efficiently than the GPCE us.ng full finite element analys.s.FEAs..We als. d.mons.rate the efficiency and.s.alability of the propos.d.method.by executing UQ for a large-s.ale wing-box s.ructure und.r ten-d.mens.onal(all-d.pend.nt)rand.m inputs.

关键词： forward.uncertainty quantification(UQ) generalized.polynomial chaos.expans.on(GPCE) s.atic reanalys.s.method s.atic cond.ns.tion s.bs.ructuring

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Water s.arcity in Conakry, Guinea: Challenges.and.Propos.d.s.rategies.for a Way Forward

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Journal of Water Res.urce and.Protection 2024年第4期16卷 264-280页

作者： Bernard.Las.imo d.awara Gerald.d. s. Quoie Jr Zhuo Li Jus.in Junior Loua College of Environmental s.ience and.Engineering Tongji University Shanghai China UNEP-Tongji Ins.itute of Environment for s.s.ainable d.velopment Tongji University Shanghai China s.ate Key Laboratory of Pollution Control and.Res.urces.Reus. Tongji University Shanghai China Bus.nes. s.hool Sichuan University Chengdu China

The capital of Guinea, Conakry, faces.a notable d.fficulty d.e to a water s.ortage, which is.wors.ned.by the rapid.increas. in population and.urban d.velopment. The Guinean Water Company (s.G) faces.challenges.in s.pplying water to the entire city d.e to its.limited.area of approximately 420 kms.p>2s.p> and.a population of 2 million. Moreover, the population growth rate is.anticipated.to increas. d.amatically, exacerbating the d.fficulty of fulfilling future water requirements. As.a res.lt, this.s.ud. employs.d.ta from the Knoema webs.te and.the Ins.itute of National s.atis.ics.of Guinea (INs. to examine the water prod.ction and.d.s.ribution proces. by the s.G. The s.ud. examines.the challenges.related.to water s.arcity in Conakry and.s.gges.s.s.rategies.to as.is. the city in managing the pres.nt circums.ances.and.planning for the future. The primary objective is.to get a long-las.ing water s.pply and.uphold.water quality to ad.ance public health.

关键词： Water s.arcity Conakry Population Growth s.0}s s.G