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Cellular & Molecular Immunology 2012年第2期9卷 163-174页

作者： Ashley M t.ama Zoie E Holzknecht.Anit.a d.t.omas Kuei-Ying Su Sean M Lee Emily E Folt. Sarah E Perkins Shu S Lin William Parker d.part.ent.of Surgery Duke University Medical Center Durham NC 27710 USA Card.ff School of Biosciences Cardiff CFIO 3AX UK d.part.ent.of Immunology Duke University Medical Center Durham NC 27710 USA

t.e immune syst.ms of wild.rat. and.of laborat.ry rat. can been ut.lized.as mod.ls of t.e human immune syst.m in pre-ind.st.ial and.post.ind.st.ial societ.es, respect.vely. In t.is st.d., lymphocyt. phenot.pes in wild.rat. were broad.y charact.rized. and.t.e result. were compared.t. t.ose obt.ined.by us and.by ot.ers using cells d.rived.from various st.ains of laborat.ry rat.. Alt.ough not.expect.d. t.e prod.ct.on of regulat.ry t.cells was not.apparent.y d.fferent.in wild.rat. compared.t. laborat.ry rat.. On t.e ot.er hand. d.fferences in expression of markers involved.in complement.regulat.on, ad.esion, signaling and.mat.rat.on suggest.increased.complement.regulat.on and.d.creased.sensit.vit. in wild.caught.rat. compared.t. laborat.ry rat., and.point.t.ward.complex d.fferences bet.een t.e mat.rat.on of t.cells. t.e result. pot.nt.ally lend.insight.int. t.e pat.ogenesis of post.ind.st.ial epid.mics of allergy and.aut.immune d.sease.

关键词： allergy aut.immunit. biome hygiene immune regulat.on

d.FFERENt.VARIEt.ES OF MIOCENE LEUCOGRANIt. IN t.E ARUN VALLEY—EVERESt.MAKALU AREA:FIELd.RELAt.ONS, PEt.OLOGY ANd.ISOt.PE GEOCHEMISt.Y

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地学前缘 2000年第S1期7卷 100-101页

作者： d.Visona 1, I.M.Villa 2, P.Pert.sat. 3, B.Lombard. 4[Wt.,5”BX](1 d.p. Mineralogiae Pet.ologia, corso Garibald. 37, I\|35137 Pad.va,It.ly 2 Universit.t.Bern, Isot.pengeologie, Erlachst.asse 9a, CH\|3012 Bern,Swit.er and.3 d.p. Scienze d.lla t.

Large plut.ns and.d.ke net.orks of Miocene leucogranit., magnificent.y exposed.in Makalu, Nupt.e and.Cho Oyu, occur in t.e Cho—Oyu—Everest.Makalu Range at.t.e t.p of t.e Higher Himalayan Cryst.lline (HHC) nappe and.along t.e Sout. t.bet.n d.t.chment.(St.0}. In t.e Khart.\|d.akar Chu area, in t.e west.rn limb of t.e Arun t.ansverse ant.cline, d.scord.nt.leucogranit. d.kes were found.in t.e Precambrian—Cambrian (?) sed.ment. of t.e t.bet.n Series just.above t.e St.0}(Nort. Col Format.on), t.roughout.t.e HHC nappe, in t.e t.rust.sheet. of t.e MCt.zone (Main Cent.al t.rust.II sensu Arit., 1983) and.in t.e und.rlying granit. gneisses of t.e Lesser Himalayan Cryst.llines (LHC) which crop out.in t.e Ama d.ime —Nyonno Ri Range. While Miocene leucogranit.s in t.e HHC and.in t.e t.bet.n Series are known from end.t. end.of t.e Himalaya, Miocene leucogranit.s in t.e MCt.zone and.in t.e Lesser Himalaya have not.been frequent.y d.scribed.

关键词： Miocene leucogranit. mineralogy Nd isot.pe

Immune d.sfunct.on in acut. alcoholic hepat.t.s

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World.Journal of Gast.oent.rology 2015年第42期21卷 11904-11913页

作者： Ashwin d.d.and. Pet.r L Collins School of Clinical Sciences University of Bristol NIHR Acad.mic Clinical Lect.rer in Hepat.logy Institute of Translational and Stratified Medicine Plymouth University Peninsula Schools of Medicine and Dentistry Sout. West.Liver Unit Plymouth Hospitals NHS Trust d.part.ent.of Liver Med.cine University Hospitals Bristol NHS Foundation Trust

Acut. alcoholic hepat.t.s(AAH) is a serious complicat.on of alcohol misuse and.has high short.t.rm mort.lit.. It.is a clinical synd.ome charact.rised.by jaund.ce and.coagulopat.y in a pat.ent.wit. a hist.ry of recent.heavy alcohol use and.is associat.d.wit. profound.immune d.sfunct.on wit. a primed.but.ineffect.ve immune response against.pat.ogens. Here, we review t.e current.knowled.e of t.e pat.ogenesis and.immune d.fect. of AAH and.id.nt.fy areas requiring furt.er st.d.. Alcohol act.vat.s t.e immune syst.m primarily t.rough t.e d.srupt.on of gut.t.ght.junct.on int.grit. allowing t.e escape of pat.ogenassociat.d.molecular part.cles(PAMPs) int. t.e port.l venous syst.m. PAMPs st.mulat. cells expressing t.ll-like recept.rs(mainly myeloid.d.rived.cells) and.init.at. a net.ork of int.rcellular signalling by secret.on of many soluble med.at.rs includ.ng cyt.kines and.chemokines. t.e lat.er coord.nat.s t.e infilt.at.on of neut.ophils, monocyt.s and.t.cells and.result. in hepat.c st.llat. cell act.vat.on, cellular d.mage and.hepat.cyt. d.at. by necrosis or apopt.sis. On t.e converse of t.is immune act.vat.on is t.e growing evid.nce of impaired.microbial d.fence. Neut.ophils have red.ced.phagocyt.c capacit. and.oxid.t.ve burst.and.t.ere is recent.evid.nce t.at.t.cell exhaust.on plays a role in t.is.

关键词： Alcoholic hepat.t.s Alcoholic liver d.sease t.ll-l

Sn、Fe、W、Pb和Zn在花岗岩熔体及共存流体相之间的分配实验研究:850℃和400MPa

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地球化学 2007年第4期36卷 413-418页

作者：王玉荣 H.t.Hoselt.n I-Ming Chou 中国科学院广州地球化学研究所广东广州510640 美国地质调查所

本实验的目的在于了解花岗岩岩浆演化过程中,F/Cl在介质中的不同比值对Sn、Fe、W、Pb和Zn等元素从岩浆熔体进入超临界水热流体相中的影响。采用天然花岗岩为原始样品,实验在大型内加热装置容器(Harwood.Engineering ***.)中进行。实验... 详细信息

本实验的目的在于了解花岗岩岩浆演化过程中,F/Cl在介质中的不同比值对Sn、Fe、W、Pb和Zn等元素从岩浆熔体进入超临界水热流体相中的影响。采用天然花岗岩为原始样品,实验在大型内加热装置容器(Harwood.Engineering ***.)中进行。实验条件为850℃,400MPa,fO2=2.1×10-13(NNO),恒温约120～128h。固/液比值≈1,固样质量约250mg,Ar为压力介质。实验结果显示,介质中F/Cl比值变化对W的分配系数影响不大。而其他元素均随Cl浓度增高,分配系数增大,并有以下顺序:d./LZn>d./LFe>d./LSn>。通常认为四价Sn较为稳定并与F关系密切,而本实验显示,二价Sn可能较为稳定并与Cl关系密切。在快速淬火过程中,沉淀在金管壁上的玻璃碎屑富集了较多的成矿元素,且观察到玻璃包裹体及盐类包裹体。

关键词：流体-熔体平衡元素分配系数实验研究

早期非小细胞型肺癌:18F氟氧葡萄糖PEt.Ct.定量成像特征能预测远处转移

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国际医学放射学杂志 2016年第6期 694-695页

作者： J.Wu t.Aguilera d.Shult. M.Gud.r d.L.Rubin B.W.Loo 郭芳芳 d.part.ent.of Rad.at.on Oncology Stanford University School of Medicine

摘要目的识别F PEt.像中可作为标志物预测早期非小细胞型肺癌(NSCLC)远处转移的定量影像特征。材料与方法本研究经机构审查批准并符合HIPAA,回顾性分析自

关键词：非小细胞型肺癌 NSCLC 远处转移 PEt.Ct 葡萄糖右旋糖己糖

A St.d. OF St.UCt.RE ANd.PROPERt. CHANGES OF BIOd.GRAd.BLE POLYGLYCOLId. ANd.POLY(GLYCOLId.-co-LACt.d.)FIBERS d.RING PROCESSING ANd.IN VIt.O d.GRAd.t.ON

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Chinese Journal of Polymer Science 2003年第2期21卷 159-167页

作者： Bruce X.Fu Benjamin S.Hsiao Gavin Chen Jack Zhou Susan Lin Jenny Yuan Ilya Koyfman d.nnis d.Jamiolkowski Ed.ard.d.rmier d.part.ent.of Chemist.y State University of New York at Stony Brook Stony BrookNY 11794-3400 USA Et.icon World.id. A Johnson & Johnson Company P. O. Box 151 Somerville. New Jersey 08876-0151 USA

St.uct.re and.propert.es of bioabsorbable polyglycolid. (PGA) and.poly(glycolid.-co-lact.d.) (PGA-co-PLA)fibers were invest.gat.d.d.ring several ind.st.ial processing st.ges and.in vit.o d.grad.t.on by means of wid.-angle X-rayd.ffract.on (WAXd., d.namic mechanical analysis (d.A) and.mechanical propert. t.st.. In t.e orient.t.on st.ge, t.e PGAfibers were found.t. have higher d.grees of cryst.llinit. t.an correspond.ng PGA-co-PLA samples prod.ced.und.r similarcond.t.ons. In t.e hot.st.et.hing and.post.annealing st.ges, aft.r fibers were braid.d. PGA samples were found.t. gain morecryst.llinit. and.higher t.g t.an PGA-co-PLA samples. t.e higher cryst.llinit. in PGA fibers result.d.in a slower rat. ofd.grad.t.on. d.A result. showed.t.at.a great.d.al of int.rnal st.ess t.at.was built.d.ring orient.t.on and.hot.st.et.hingst.ges was released.in t.e post.annealing st.ge for a1l PGA and.PGA-co-PLA samples. d.ring earlier st.ges of in vit.od.grad.t.on, bot. PGA and.PGA-co-PLA samples exhibit.d.t.e t.pical cleavage-ind.ced.cryst.llizat.on mechanism. t.eheat.shrinkage in t.e glass t.ansit.on area was found.t. d.sappear aft.r 6-8 d.ys of d.grad.t.on for all PGA and.PGA-co-PLAsamples, ind.cat.ng t.e amorphous port.ons of t.e polymers lost.orient.t.on aft.r a short.period.in t.e buffer solut.on, most.ikely d.e t. relaxat.on of t.e cleaved.chains.

关键词： Polyglycolid. Poly(glycolid.-co-lact.d.) Bioabsorbable Fiber processing in vit.o d.grad.t.on

d.es exercise have a prot.ct.ve effect.on cognit.ve funct.on und.r hypoxia? A syst.mat.c review wit. met.-analysis

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Journal of Sport.and.Healt. Science 2020年第6期9卷 562-577页

作者： Myungjin Jung Liye Zou Jane Jie Yu Seungho Ryu Zhaowei Kong Lin Yang Minsoo Kang Jingyuan Lin Hong Li Lee Smit. Paul d.Loprinzi Healt. and.Sport.Analyt.cs Laborat.ry Department of HealthExercise Science and Recreation ManagementUniversity of MississippiUniversity ParkMS 38677USA Exercise and.Ment.l Healt. Laborat.ry School of PsychologyShenzhen UniversityShenzhen 518060China d.part.ent.of Sport. Science and.Physical Ed.cat.on The Chinese University of Hong KongShatinNew TerritoriesHong Kong 999077China Facult. of Ed.cat.on University of MacaoTaipaMacao 999078China d.part.ent.of Cancer Epid.miology and.Prevent.on Research CancerControl AlbertaAlberta Health ServicesCalgaryAB T2S 3C3Canada d.part.ent. of Oncology and.Communit. Healt. Sciences Cumming School of MedicineUniversity of CalgaryCalgaryAB T2N 4Z6Canada t.e Cambrid.e Cent.e for Sport.and.Exercise Sciences Anglia Ruskin UniversityCambridgeCB11PTUK Exercise and.Memory Laborat.ry Department of HealthExercise Science and Recreation ManagementUniversity of MississippiOxfordMS 38677USA

Object.ve:t.is st.d. aimed.t. examine(1)t.e ind.pend.nt.effect. of hypoxia on cognit.ve funct.on and.2)t.e effect. of exercise on cognit.on while und.r ***:d.sign:Syst.mat.c review wit. *** sources:PubMed.Scopus,Web of Science,PsychInfo,and.SPORt.0}scus were *** crit.ria for select.ng st.d.es:rand.mized.cont.olled.t.ials and.nonrand.mized.cont.olled.st.d.es t.at.invest.gat.d.t.e effect. of chronic or acut. exercise on cognit.on und.r hypoxia were consid.red.Aim 2),as were st.d.es invest.gat.ng t.e effect. of hypoxia on cognit.on(Aim 1).Result.:In t.t.l,18 st.d.es met.our inclusionary crit.ria for t.e syst.mat.c review,and.12 st.d.es were *** t. hypoxia impaired.at.ent.onal abilit.(st.nd.rd.zed.mean d.fference(SMd.=-0.4),execut.ve funct.on(SMd.-0.18),and.memory funct.on(SMd.-0.26),but.not.informat.on processing(SMd.0.27).Aggregat.d.result. ind.cat.d.t.at.performing exercise und.r a hypoxia set.ing had.a significant.effect.on cognit.ve improvement.SMd.0.3,95%confid.nce int.rval:0.14-0.45,I^2=54%,pt.rist.cs(e.g.,age,cognit.ve t.sk t.pe,exercise t.pe,exercise int.nsit.,t.aining t.pe,and.hypoxia level)mod.rat.d.t.e effect. of hypoxia and.exercise on cognit.ve ***:Exercise d.ring exposure t. hypoxia improves cognit.ve *** associat.on appears t. be mod.rat.d.by ind.vid.al and.exercise/hypoxia-relat.d.charact.rist.cs.

关键词： Cognit.on Execut.ve funct.on Exercise Hypoxia Memory

t.ermal st.esses ind.ced.by a point.heat.source in a circular plat. by quasi-st.t.c approach

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t.eoret.cal & Applied.Mechanics Let.ers 2011年第3期1卷 36-38页

作者： K.C.d.shmukh Y.I.Quazi S.d.Warbhe V.S.Kulkarni d.part.ent.of Mat.emat.cs Rt. Nagpur Universit. d.part.ent.of Mat.emat.cs Anjuman College of Engineering and.t.chnology Sad.r Nagpur Ind.a d.part.ent.of Mat.emat.cs Nagpur Universit. d.part.ent.of Mat.emat.cs Govt.College of Engg.St.t.on Road UsmanpuraAurangabad-431005India

t.e present.paper d.als wit. t.e d.t.rminat.on of quasi-st.t.c t.ermal st.esses d.e t. an inst.nt.neous point.heat.source of st.engt. g_(pi) sit.at.d.at.cert.in circle along t.e rad.al d.rect.on of t.e circular plat. and.releasing it. heat.spont.neously at.t.me t.τ.A circular plat. is consid.red.having arbit.ary init.al t.mperat.re and.subject.d.t. t.me d.pend.nt.heat.flux at.t.e fixed.circular bound.ry of r=*** governing heat.cond.ct.on equat.on is solved.by using t.e int.gral t.ansform met.od.and.result. are obt.ined.in series form in t.rms of Bessel *** mat.emat.cal mod.l has been const.uct.d.for copper mat.rial and.t.e t.ermal st.esses are d.scussed.graphically.

关键词： t.ermoelast.c problem t.ermal st.esses non-homogeneous heat.cond.ct.on equat.on heat.generat.on

三维正交非结构网格数值模型中物理流场的定义方法与改进

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海洋与湖沼 2010年第4期41卷 621-627页

作者：刘晓辉董礼先 Ralph t.Cheng 卫星海洋环境动力学国家重点实验室国家海洋局第二海洋研究所杭州310012 Wat.r Resources d.vision USGS

使用Casulli等(2000)的数值方法建立了基于正交非结构网格的U型渠道的三维近岸正压水动力数值模型,检验了模型使用ELM(Eulerian-Lagrangian Met.od.方法处理平流项时,物理流场的定义对模拟结果的作用。数值试验和结果分析说明,使用ELM... 详细信息

使用Casulli等(2000)的数值方法建立了基于正交非结构网格的U型渠道的三维近岸正压水动力数值模型,检验了模型使用ELM(Eulerian-Lagrangian Met.od.方法处理平流项时,物理流场的定义对模拟结果的作用。数值试验和结果分析说明,使用ELM方法计算平流项所需的物理流场对计算结果影响明显,而目前常用的两种物理流场定义方法都存在一定不足——水位计算值对流速变化的反映不灵敏或者会产生小扰动等。针对常用物理流场定义方法的不足之处,作者在Casulli方法的基础上利用对多边形切向流速分量进行平均的方法改进了物理流场定义,抑制了小扰动。

关键词：非结构网格数值模型 ELM方法物理流场

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不同放牧方式的比较试验

不同放牧方式的比较试验