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Preval.nce, Risk Factors and Intra-Hospital.Outcom.s Rel.ting to Peri-Intraventricul.r Hem.rrhage in Prem.ture Newborns of Gestational.Age l.ss than 34 Weeks

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Open Journal.of Obstetrics and Gynecol.gy 2021年第7期11卷 898-910页

作者： Ana Frante de Hol.nda Pinto Vasconcel.s Kal.ny da Sil.a Gal.ão Rodrigo daudt Tenório Ana Cl.ra m.nteiro l.ranjeira délia maria de m. l. herrmann diêgo l.cas Ram.s e Sil.a Juliana Barbosa Nunes Caval.ante Jam.l.e Cam.os Sousa Eucl.des m.urício Trindade Fil.o Biol.gical.Science Nucl.us Cesmac University Center Maceió Alagoas Brasil Biol.gical.Science Nucl.us State University of Health Science of Alagoas-UNCISAL Maceió Alagoas Brasil departm.nt of Biol.gical.Science Federal University of Alagoas Maceió Alagoas Brasil

Peri-intraventricul.r hem.rrhage is one of the m.in causes of neurol.gical.im.airm.nt in prem.ture newborns. To control.their risk factors is necessary in view of the increasing survival.of extrem. preterm.infants. Ob... 详细信息

Peri-intraventricul.r hem.rrhage is one of the m.in causes of neurol.gical.im.airm.nt in prem.ture newborns. To control their risk factors is necessary in view of the increasing survival of extreme preterm infants. Objective: To evaluate the prevalence of peri-intraventricular hemorrhage in premature newborns, identify the risk factors and observe the frequencies of intra-hospital outcomes of interests. Methods: This study was done in Brazil. This was an observational, analytical longitudinal and prospective study. The subjects included were newborns of gestational age less than 34 weeks who were admitted to two public hospitals between May and November 2015. To assess possible associated factors, obstetric, perinatal and neonatal data were analyzed (chorioamnionitis, antenatal corticosteroids, gestational age, newborn weight, Apgar score at 1 and 5 minutes, resuscitation in the del.very room. surfactant in the del.very room. newborn transferre

关键词： Prem.ture Newborn Peri-Intraventricul.r Hem.rrhage Risk Factors Trans-fontanel.e Ul.rasonography

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differential.responses to artificial.sel.ction on oviposition site preferences in drosophil. m.l.nogaster and d. sim.l.ns

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Insect Science 2015年第6期22卷 821-828页

作者： Eduardo m. Soto maria I. l. Betti Juan Hurtado Esteban Hasson departam.nto de Ecol.gia Genetica y Evolucion IEGEBA (CONICET-UBA) Facultad de Ciencias Exactas y Naturales Universidad deBuenos Aires Buenos Aires Argentina

The preference-perform.nce rel.tionship in pl.nt-insect interactions is a cen- tral.them. in evol.tionary ecol.gy. Am.ng m.ny insects, eggs are vul.erabl. and l.rvae have l.m.ted m.bil.ty, m.king the choice of an appropriate oviposition site one of the m.st im.ortant decisions for a fem.l.. We investigated the evol.tion of oviposition preferences in drosophil. m.l.nogaster m.igen and drosophil. sim.l.ns Sturtevant by artificial.y sel.cting for the preference for 2 natural.resources, grape and quince. The m.in finding of our study is the differential.responses of d. m.l.nogaster and d. sim.l.ns. Al.hough preferences evol.ed in the experim.ntal.popul.tions of d. m.l.nogaster, responses were not consistent with the sel.ction regim.s appl.ed. In contrast, responses in d. sim.l.ns were consistent with expectations, dem.nstrating that this species has sel.ctabl. genetic variation for the trait. Furtherm.re, crosses between d. sim.l.ns divergent l.nes showed that the genetic factors invol.ed in grape preference appear to be l.rgel. recessive. In sum.ary, our artificial.sel.ction study suggests that d. m.l.nogaster and d. sim.l.ns possess different genetic architectures for this trait.

关键词： artificial.sel.ction behavior drosophil. genetic variation natural.esources oviposition preference

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dissim.l.r titanium.al.m.num.friction stir wel.ing l.p joints by experim.nts and num.rical.sim.l.tion

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Advances in m.nufacturing 2016年第4期4卷 287-295页

作者： G. Buffa m. de l.si E. Sciortino l. Fratini epartm.nt of Chem.cal Management Computer and Mechanical Engineering University of Palermo Viale delle Scienze 90128 Palermo Italy

dissim.l.r stir wel.ing （FSW） l.p joints were produced by friction out of Ti6A14V titanium.al.oy and AA2024 al.m.num.al.oy sheets. The joints, wel.4}d with varying tool.rotation and feed rate, were studied by ana- l.zing the m.xim.m.shear strength, Vickers m.crohardness and optical.observations. A dedicated num.rical.m.del. abl. to take into account the presence of the two different al.oys, was used to highl.ght the effects of the process param.ters on tem.erature distribution, strain distribution, and m.terial.fl.w. The com.ined anal.sis of experim.ntal.m.asurem.nts and num.rical.predictions al.owed expl.ining the effects of tool.rotation and feed rate on the m.terial.fl.w. It was found that tool.rotation had a l.rger im.act on the joint effectiveness with respect to feed rate. A com.etition between m.terial.m.xing and heat input occurs with increasing tool.rotation, resul.ing in higher joint strength when l.wer val.es of tool.rotation are used.

关键词： Finite el.m.nt m.thod (FEm. Ti6A14V AA2024 Friction stir wel.ing (FSW) l.p joint

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Reinforcem.nt of Hydroxypropyl.el.ul.se Fil.0} by Cel.ul.se Nanocrystal. in the Presence of Surfactants

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Chinese Journal.of Pol.m.r Science 2016年第11期34卷 1301-1301,1302-1310页

作者： Noor Rehm.n maria Inez G.de m.randa Sim.ne m.l.Rosa Cl.ra I.d.Bica Instituto de Quim.ca Universidade Federal do Rio Grande do Sul 91501-970 Porto Alegre/RS Brazil departm.nt of Chem.stry Shaheed Benazir Bhutto University 18000 Sheringal Dir (Upper) KPK Pakistan Instituto de Ciencias Exatas e Tecnol.gicas Universidade FEEVALE Campus Ⅱ 93525-075 Novo Hamburgo/RS Brazil

Hydroxypropyl.el.ul.se（HPC） fil.0} were prepared by casting with cel.ul.se nanocrystal. in the presence of anionic surfactant sodium.dodecyl.ul.hate（SdS） and cationic surfactant hexadecyl.rim.thyl.am.onium.brom.de（CTAB）. The cel.ul.se nanocrystal. were isol.ted from.m.ize straw, a biom.ss source produced in huge quantities as an agrowaste in Brazil. These bionanocom.osite fil.0} had good transparency and their surface hydrophil.c character was evidenced by static contact angl. m.asurem.nts. Therm.gravim.try（TGA） m.asurem.nt reveal.d that nanocrystal. and surfactants changed the therm.l.stabil.ty of the HPC fil.0}. dynam.c m.chanical.anal.sis（dm.） showed that the tensil. storage and l.ss m.dul. of the HPC fil.0} increased by increasing the contents of cel.ul.se nanocrystal. and surfactants, especial.y in the case of CTAB. This good reinforcing effect of HPC m.trix can be expl.ined as due to el.ctrostatic attractive interactions brought about by the presence of CTAB and the nanocrystal..

关键词： surfactant attractive hydrophil.c cel.ul.se reinforcing m.dul.s cationic el.ctrostatic tensil. am.onium

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m.l.cul.r profil.ng of indol.nt hum.n prostate cancer： tackl.ng technical.chal.enges to achieve high-fidel.ty genom.-wide data

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Asian Journal.of Androl.gy 2012年第3期14卷 385-392,I0005页

作者： Thom.s A. dunn Hel.n l. Fedor Angel. m. de m.rzo Jun l.o departm.nt of Urol.gy Johns Hopkins University Baltimore MD 21287 USA departm.nt of Pathol.gy Johns Hopkins University Baltimore MD 21287 USA

The contem.orary probl.m.of prostate cancer overtreatm.nt can be partial.y attributed to the diagnosis of potential.y indol.nt prostate cancers that pose l.w risk to aged m.n, and l.ck of sufficientl. accurate risk stratification m.thods to reliabl. seek out m.n with indol.nt diseases. Since progressive acquisition and accum.l.tion of genom.c al.erations, both genetic and epigenetic, is a defining feature of al. hum.n cancers at different stages of disease progression, it is hypothesized that RNA and dNA al.erations characteristic of indol.nt prostate tum.rs m.y be different from.those previousl. characterized in the setting of cl.nical.y significant prostate cancer. Approaches capabl. of detecting such al.erations on a genom.-wide l.vel.are the m.st prom.sing. Such anal.sis m.y uncover m.l.cul.r events defining earl. initiating stages al.ng the natural.history of prostate cancer progression, and ul.im.tel. l.ad to rational.devel.pm.nt of risk stratification m.thods for identification of m.n who can safel. forego treatm.nt. However, defining and characterizing indol.nt prostate cancer in a cl.nical.y rel.vant context rem.ins a chal.enge, particul.rl. when genom.-wide approaches are em.l.yed to profil. form.l.n-fixed paraffin-em.edded （FFPE） tissue specim.ns. Here, we provide the conceptual.basis underl.ing the im.ortance of understanding indol.nt prostate cancer from.m.l.cul.r profil.ng studies, identify the key hurdl.s in sam.l. acquisition and variabl.s that affect m.l.cul.r data derived from.FFPE tissues, and highl.ght recent progresses in efforts to address these technical.chal.enges.

关键词： active surveil.ance form.l.n-fixed paraffin-em.edded indol.nt prostate cancer m.croarray m.l.cul.r profil.ng prostatecancer prostate cancer progression risk stratification

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Brain-derived neurotrophic factor signal.ng in the neurom.scul.r junction during devel.pm.ntal.axonal.com.etition and synapse el.m.nation

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Neural.Regeneration Research 2025年第2期20卷 394-401页

作者： Josep Tom.s Víctor Cil.eros-m.ñé l.ia Just-Borràs m.rta Bal.nyà-Segura Al.ksandra Pol.shchuk l.ura Nadal.m.rta Tom.s Carol.na Sil.era-Sim.n m.nel.m.Santafé maria A.l.nuza Unitat d’Histol.gia i Neurobiol.gia(UHNeurob) Facultat de Medicina i Ciències de la SalutUniversitat Rovira i VirgiliReusSpain

during the devel.pm.nt of the nervous system.there is an overproduction of neurons and *** com.etition between neighboring nerve endings and synapses perform.ng different activity l.vel. l.ads to their el.m.nation or *** have extensivel. studied the invol.em.nt of the brain-derived neurotrophic factor-Tropom.osin-rel.ted kinase B receptor neurotrophic retrograde pathway,at the neurom.scul.r junction,in the axonal.devel.pm.nt and synapse el.m.nation process versus the synapse *** purpose of this review is to describe the neurotrophic infl.ence on devel.pm.ntal.synapse el.m.nation,in rel.tion to other m.l.cul.r pathways that we and others have found to regul.te this *** particul.r,we sum.arize our publ.shed resul.s based on transm.tter rel.ase anal.sis and axonal.counts to show the different invol.em.nt of the presynaptic acetyl.hol.ne m.scarinic autoreceptors,coupl.d to downstream.serine-threonine protein kinases A and C(PKA and PKC)and vol.age-gated cal.ium.channel.,at different nerve endings in devel.pm.ntal.*** dynam.c changes that occur sim.l.aneousl. in several.nerve term.nal. and synapses converge across a postsynaptic site,infl.ence each other,and require careful.studies to individual.ze the m.chanism. of specific *** describe an activity-dependent bal.nce(rel.ted to the extent of transm.tter rel.ase)between the presynaptic m.scarinic subtypes and the neurotrophin-m.diated TrkB/p75NTR pathways that can infl.ence the tim.ng and fate of the com.etitive interactions between the different axon *** downstream.displ.cem.nt of the PKA/PKC activity ratio to l.wer val.es,both in com.eting nerve term.nal. and at postsynaptic sites,pl.ys a rel.vant rol. in control.ing the el.m.nation of supernum.rary ***,cal.ium.entry through l.and P/Q-subtypes of vol.age-gated cal.ium.channel.(both channel. are present,together with the N-type channel.in devel.ping nerve term.nal.)contributes to red

关键词： acetyl.hol.ne rel.ase adenosine receptors axonal.com.etition brain-derived neurotrophic factor cal.ium.channel. m.tor end-pl.te m.scarinic acetyl.hol.ne receptors postnatal.synapse el.m.nation serine kinases tropom.osin-rel.ted kinase receptorB

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Com.osition of Fractional.Orl.cz m.xim.l.Operators and A1-weights on Spaces of Hom.geneous Type

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Acta m.them.tica Sinica,Engl.sh Series 2010年第8期26卷 1509-1518页

作者： Ana l. BERNARdIS Gl.dis PRAdOl.NI maria l.RENTE maria Sil.ina RIVEROS Im.l.( CONICET)-FIQ (UNl. Guemes 3450 (3000) Santa Fe Argentina departam.nto de Anal.sis m.tem.tico Facultad de CienciasUniversidad de Malaga 29071-Malaga Spain Fam.F Universidad Nacional.de Cordoba CIEm.( CONICET) 5000 Cordoba Argentina

For a Young function θ with 0 ≤α 〈 1, l.t m.,θ be the fractional.Orl.cz m.xim.l.operator defined in the context of the spaces of hom.geneous type （X, d, μ） by m.,θf（x） = supx∈（B）α ｜｜f｜｜θ,B, where ｜｜f｜｜θ,B is the m.an l.xem.urg norm.of f on a bal. B. When α= 0 we sim.l. denote it by m.. In this paper we prove that if Ф and ψare two Young functions, there exists a third Young function θ such that the com.osition m.,ψ o m. is pointwise equival.nt to m.,θ. As a consequence we prove that for som. Young functions θ, if m.,θf 〈∞a.e. and δ ∈（0,1） then （m.,θf）δ is an A1-weight.

关键词： Orl.cz m.xim.l.function spaces of hom.geneous type weights

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Apoptosis induced by a l.w-carbohydrate and high-protein diet in rat l.vers

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Worl. Journal.of Gastroenterol.gy 2016年第22期22卷 5165-5172页

作者： maria Em.lia l.m.nteiro Anal.cia R Xavier Fel.pe l.Ol.veira Porphirio JS Fil.o Vil.1} B Azeredo departm.nt of Internal.m.dicine Medicine College Fluminense Federal University Niteroi RJ 24030-210 Brazil departm.nt of Pathol.gy Medicine College Fluminense Federal University Niteroi RJ 24030-210 Brazil Biom.dical.Science Institute Federal University of Rio de Janeiro Rio de Janeiro RJ 21941-913 Brazil departm.nt of Nutrition and dietitian Nutrition College Fluminense Federal University Niteroi RJ 24030-210 Brazil

AIm. To determ.ne whether high-protein, high-fat, and l.w-carbohydrate diets can cause l.sions in rat ***: We random.y divided 20 fem.l. Wistar rats into a control.diet group and an experim.ntal.diet group. Anim.l. in the control.group received an AIN-93 m.diet, and anim.l. in the experim.ntal.group received an Atkins-based diet(59.46% protein, 31.77% fat, and 8.77% carbohydrate). After 8 wk, the rats were anesthetized and exsanguinated for transam.nases anal.sis, and their l.vers were rem.ved for fl.w cytom.try, im.unohistochem.stry, and l.ght m.croscopy studies. We expressed the data as m.an ± standard deviation(sd) assum.ng unpaired and param.tric data; we anal.zed differences using the student's t-test. statistical.significance was set at P d that pl.sm. al.nine am.notransferase and aspartate am.notransferase l.vel. were significantl. higher in the experim.ntal.group than in the control.group. According to fl.w cytom.try, the percentages of nonviabl. cel.s were 11.67% ± 1.12% for earl. apoptosis, 12.07% ± 1.11% for l.te apoptosis, and 7.11% ± 0.44% for non-apoptotic death in the experim.ntal.diet group and 3.73% ± 0.50% for earl. apoptosis, 5.67% ± 0.72% for l.te apoptosis, and 3.82% ± 0.28% for non-apoptotic death in the control.diet group. The m.an percentage of earl. apoptosis was higher in the experim.ntal.diet group than in the control.diet group. Im.unohistochem.stry for autophagy was negative in both groups. sinusoidal.dil.tion around the central.vein and sm.l. hepatocytes was onl. observed in the experim.ntal.diet group, and fibrosis was not identified by hem.toxyl.n-eosin or Trichrom. m.sson staining in either ***: Eight weeks of an experim.ntal.diet resul.ed in cel.ul.r and histopathol.gical.l.sions in rat l.vers. Apoptosis was our principal.finding; el.vated pl.sm. transam.nases dem.nstrate hepatic l.sions.

关键词： Apoptosis l.ver injury High-protein diet High-fat diet l.w-carbohydrate diet

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Evol.tionary Genom.cs of Weedy Rice in the USA

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Journal.of Integrative Pl.nt Biol.gy 2007年第6期49卷 811-816页

作者： Kenneth m. Ol.en Ana l. Caicedo Yul.n Jia departm.nt of Biol.gy Washington University St Louis MO 63130 USA departm.nt of Biol.gy University of Massachusetts Amherst MA 01003 USA USdA-ARS dal. Bum.ers National.Rice Research Center Stuttgart AR 72160 USA

Red rice Is an Interfertl.e, weedy form.of cul.ivated rice （Oryza sativa l.） that com.etes aggressivel. with the crop In the southern US, reducing yiel.s and contam.nating harvests. No wil. Oryza species occur In North Am.rica and the weed has been proposed to have evol.ed through m.l.ipl. m.chanism., Incl.ding ＂de-dom.stication＂ of US crop cul.l.ars, accidental.introduction of Asian weeds, and hybridization between US crops and Asian wil./weedy Oryza strains. The phenotype of US red rice ranges from.＂crop m.m.cs＂, which share som. dom.stication traits with the crop, to strains cl.sel. resem.l.ng Asian wil. Oryza species. Assessm.nts of genetic diversity have Indicated that m.ny weed strains are cl.sel. rel.ted to Asian taxa （Incl.ding indica and aus rice varieties, which have never been cul.ivated In the US, and the Asian crop progenitor O. rufl.ogon）, whereas others show genetic sim.l.rity to the tropical.Japonica varieties cul.ivated In the southern US. Herein, we review what Is known about the evol.tionary origins and genetic diversity of US red rice and describe an ongoing research project to further characterize the evol.tionary genom.cs of this aggressive weed.

关键词： crop-weed introgression de-dom.stication Oryza sativa weed evol.tion weedy rice.

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General.zed Coherent States of a Particl. in a Tim.-dependent l.near Potential

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Chinese Physics l.tters 2009年第7期26卷 36-39页

作者： l. Krache m. m.am.che Y. Saadi A. Beniaiche l.b PQSd Faculté des Sciences Université Ferhat Abbas de Sétif Sétif 19000 Algeria l.b SPONl Faculté des Sciences de l'Ingénieur Université Ferhat Abbas de Sétif Sétif 19000 Algeria

We derive, with an invariant operator m.thod and unitary transform.tion approach, that the Schr6dinger equation with a tim.-dependent l.near potential.possesses an infinite string of shape-preseving wave-packet states 1φ,λ （t） having cl.ssical.m.tion. The qual.tative properties of the invariant eigenval.e spectrum.（discrete or continuous） are described separatel. for the different val.es of the frequency ω of a harm.nic oscil.ator. It is al.o shown that, for a discrete eigenval.e spectrum. the states 1φ,λ （t） coul. be obtained from.the coherent state 1φ,λ （t）.

关键词： m.them.tical.physics Quantum.inform.tion and quantum.m.chanics

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