检索结果-南通市图书馆

Possibilities and impossibilities of magnetic nanoparticle use in the control of infectious biofilms

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2021年第10期69卷 69-78页

作者： Kecheng Quan Zexin Zhang Yijin Ren Henk J.Busscher Henny C.van der Mei Brandon w.peterson College of Chemistry Chemical Engineering and Materials ScienceSoochow UniversitySuzhou215123China University of Groningen and University Medical Center Groningen Department of Biomedical Engineering9713 AVGroningenthe Netherlands University of Groningen and University Medical Center Groningen Department of OrthodonticsHanzeplein 19713 GZGroningenthe Netherlands

Targeting of chemotherapeutics towards a tumor site by magnetic nanocarriers is considered promising in *** nanoparticles are also considered for use in infection-control as a new means to prevent antimicrobial resistance from becoming the number one cause of death by the year *** this end,magnetic nanoparticles can either be loaded with an antimicrobial for use as a delivery vehicle or modified to acquire intrinsic antimicrobial *** nanoparticles can also be used for the local generation of heat to kill infectious *** appealing for tumor-and infectioncontrol,injection in the blood circulation may yield reticuloendothelial uptake and physical obstruction in organs that yield reduced targeting *** can be prevented with suitable surface ***,precise techniques to direct magnetic nanoparticles towards a target site are *** problem of precise targeting is aggravated in infection-control due to the micrometer-size of infectious biofilms,as opposed to targeting of nanoparticles towards centimeter-sized *** review aims to identify possibilities and impossibilities of magnetic targeting of nanoparticles for *** first review targeting techniques and the spatial resolution they can achieve as well as surface-chemical modifications of magnetic nanoparticles to enhance their targeting efficiency and antimicrobial *** is concluded that targeting problems encountered in tumor-control using magnetic nanoparticles,are neglected in most studies on their potential application in *** biofilm targeting by smart,self-adaptive and pH-responsive,antimicrobial nanocarriers for instance,seems easier to achieve than magnetic *** leads to the conclusion that magnetic targeting of nanoparticles for the control of micrometer-sized infectious biofilms may be less promising than initially ***,using propulsion rather than pr

关键词： Magnetic nanoparticles Magnetic targeting Biofilm Infection Antimicrobials

An analysis of air pollution associated with the 2023 sand and dust storms over China:Aerosol properties and PM_(10) variability

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Geoscience Frontiers 2024年第2期15卷 155-168页

作者： Mikalai Filonchyk Michael P.peterson Lifeng Zhang Haowen Yan Faculty of Geomatics Lanzhou Jiaotong UniversityLanzhou 730070China Gansu Provincial Engineering Laboratory for National Geographic State Monitoring Lanzhou 730070China Department of Geography/Geology University of Nebraska OmahaOmahaNE 68182USA

Every spring,a large part of China is confronted with sand and dust storms(SDS)–mainly originating in the Gobi(including Chinese and Mongolian Gobi)and Taklamakan *** March-April 2023,most of northern,northwestern and northeastern China was struck by three sandstorms that affected an area with more than 500 million *** this study,aerosol optical,microphysical and radiative properties were studied during these SDS events using an integrated approach that combines satellite,terrestrial and re-analysis *** results showed that dusty conditions were observed in most areas north of the Yangtze River(Chang Jiang)with daily average PM_(10)concentrations exceeding 1000 lg/m^(3) in many *** aerosol optical depth(AOD)at 550 nm during three SDS events exceeded a value of 1 throughout nearly the entire northern part of the *** AERONET data obtained from the AOE_Baotou site showed a significant increase in total AOD and a corresponding decrease in AE during the *** single scattering albedo(SSA),asymmetry parameter(ASY),real refractive index(RRI)and imaginary refractive index(IRI)values indicate an abundance of scattering coarse-mode *** radiative forcing(ARF)at top of the atmosphere and at the earth’s surface was nearly always negative during the period and ranged from48.5 to+2.7 wm^(-2)and from180.8 to66.6 wm^(-2),resulting in high positive ARF values at ATM(from+63.8 to+132.3 wm^(-2)).Each of these affects the heating of the atmosphere and cooling on the earth’s *** atmospheric heating rates ranged from 1.8 to 3.7 K day*** formation of these SDS mainly resulted from the passage of cold fronts associated with low pressure systems in the Gobi and Taklamakan deserts,creating conditions for dust to rise into the atmosphere and move further downwind.

关键词： Dust storm PM_(10) Aerosol optical depth Radiative forcing VIIRS AERONET

The Effect of Reaction Temperature, Catalyst Concentration and Alcohol Ratio in the Production of Biodiesel from Raw and Purified Castor Oil

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advances in Chemical Engineering and Science 2024年第3期14卷 137-154页

作者： Sandile Brendon Masango peterson Thokozani Ngema Olusegun Ayodeji Olagunju Suresh Ramsuroop Department of Chemical Engineering Durban University of Technology Green Engineering Group-Chemical Thermodynamics Steve Biko Campus Durban South Africa Department of Chemical Engineering Cape Peninsula University of Technology Cape Town South Africa

In this study, a homogeneous alkaline catalyst was used in the production of biodiesel from raw and refined castor oil feedstock. The effect of potassium hydroxide (KOH) as a catalyst between the two feedstocks, raw and refined castor oil was compared. The transesterification technique was utilized in this study, aiming to investigate the effect of different parameters, which include the reaction temperature, methanol-to-oil mole ratio, and catalyst concentration at a constant period of 90 minutes. The result revealed the performance of the KOH catalyst on raw castor oil yielded 98.49% FAME, which was higher than the refined castor oil which yielded 97.9% FAME. The optimal conditions obtained from refined castor oil were applied to raw castor oil because of the same properties. The fuel quality of castor oil and produced biodiesel were tested for physicochemical properties.

关键词： Biodiesel Fuel Raw Castor Oil Refined Castor Oil Transesterification Process

Blood metal concentrations and cardiac structure and function in total joint arthroplasty patients

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

world Journal of Orthopedics 2024年第8期15卷 773-782页

作者： Peter C Brennan Stephanie M peterson Thomas J O'Byrne Mariana L Laporta Cody C wyles Paul J Jannetto Garvan C Kane Maria Vassilaki Hilal Maradit Kremers Department of Orthopedic Surgery Mayo ClinicRochesterMN 55905United States Department of Quantitative Health Sciences Mayo ClinicRochesterMN 55905United States Department of Anesthesiology and Perioperative Medicine Mayo ClinicRochesterMN 55905United States Department of Laboratory Medicine and Pathology Mayo ClinicRochesterMN 55905United States Department of Cardiovascular Diseases Mayo ClinicRochesterMN 55905United States

BACKGROUND There is concern regarding potential long-term cardiotoxicity with systemic distribution of metals in total joint arthroplasty(TJA)*** To determine the association of commonly used implant metals with echocardiographic measures in TJA *** The study comprised 110 TJA patients who had a recent history of high chromium,cobalt or titanium *** underwent two-dimensional,three-dimensional,Doppler and speckle-strain transthoracic echocardiography and a blood draw to measure metal *** and sex-adjusted linear and logistic regression models were used to examine the association of metal concentrations(exposure)with echocardiographic measures(outcome).RESULTS Higher cobalt concentrations were associated with increased left ventricular end-diastolic volume(estimate 5.09;95%CI:0.02-10.17)as well as left atrial and right ventricular dilation,particularly in men but no changes in cardiac *** titanium concentrations were associated with a reduction in left ventricle global longitudinal strain(estimate 0.38;95%CI:0.70 to 0.06)and cardiac index(estimate 0.08;95%CI,-0.15 to-0.01).CONCLUSION Elevated cobalt and titanium concentrations may be associated with structural and functional cardiac changes in some *** studies are warranted to better understand the systemic effects of metals in TJA patients.

关键词： Total joint arthroplasty Metal-on-metal Cardiotoxicity Heart failure Echocardiography Cobalt

Global wild rice germplasm resources conservation alliance:world wild-Rice wiring

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Molecular Plant 2024年第4期17卷 516-518页

作者： Xiaoming Zheng Disna Ratnasekera Jiayu Fan Robert J.Henry Beng-Kah Song Kenneth M.Olsen Bal Krishna Joshi Maria Celeste N.Banaticla-Hilario Tonapha Pusadee Adane Getachew Melaku Yeyinou Laura Estelle Loko Koukham Vilayheuang Gavers K.Oppong Samuel Aduse Poku peterson w.wambugu Song Ge Aldo Merotto Junior Ohn Mar Aung Ramaiah Venuprasad Ajay Kohli wenbin Zhou Qian Qian National Key Facility for Crop Gene Resources and Genetic Improvement Institute of Crop SciencesChinese Academy of Agricultural SciencesBeijing 100081China Sanya National Research Institute of Breeding in Hainan Chinese Academy of Agricultural SciencesBeijing 100081China International Rice Research Institute DAPO Box 7777Metro Manila 4031Philippines Department of Agricultural Biology Faculty of AgricultureUniversity of RuhunaMatara 81000Sri Lanka Yazhouwan National Laboratory No.8 Huanjin RoadYazhou DistrictSanya CityHainan Province 572024China Hainan University Haikou 570228China ARC Centre of Excellence for Plant Success in Nature and Agriculture University of QueenslandBrisbaneQLD4072Australia School of Science Monash University Malaysia47500 Bandar SunwaySelangor 47500Malaysia Department of Biology Washington University in St.LouisSt.LouisMO 63130-4899USA National Agriculture Genetic Resources Center(Genebank) KhumaltarPO Box 3055KathmanduNepal Plant Biology Division Insttute of Biological SciencesUniversity of the Pilippines Los BanosLos BanosLaguna 4031Philippines Division of Agronomy Department of Plant and Soil SciencesFaculty of AgricultureChiang Mai UniversityChiang Mai 50200Thailand Bio and Emerging Technology Institute Addis Ababa 1165Ethiopia National University of Sciences TechnologiesEngineering and Mathematics(UNSTIM)Dassa-ZouméBP 14Benin National Genebank Rice and Cash Crops Research CenterNAFRIVientiane 0605Lao PDR Plant Sciences and the Bioeconomy Rothamsted ResearchHarpenden AL52JQUK UK Future Food Beacon of Excellence and School of Biosciences and University of Nottingham Nottingham LE125RDUK Department of Plant and Environmental Biology University of GhanaAccraGhana Kenya Agricultural and Livestock Research Organization Genetic Resources Research InstituteNairobi 00200Kenya Institute of Botany Chinese Academy of SciencesBeijing 100093China Federal University of Rio Grande do Sul UFRGSPorto Alegre 91501-970RSBrazil Department of Agricultur

wild relatives of crop are key genetic resources serving as diversity reservoirs for crop improvement under changing ***(Oryza sativa)is one of the most important crops in the world,providing staple food for half of the world's *** rice is thus a critical germplasm resource for sustained global food security,ensuring high production yields,improved quality,and stress resistance in the face of climate *** rice is closely related to domesticated rice and has a rich genetic diversity and exceptional adaptability to extreme *** has played a pivotal role in the history of rice hybridization and has become a key resource for rice breeding *** identification of wild-type cytoplasmic male sterility resources paved the way for the achievement of the“three lines”goal in hybrid rice,leading to a significant increase in rice *** addition,the use of resistance alleles found in wild rice is making rice production more resilient to losses caused by environmental ***,wild rice germplasm resources are threatened due to habitat destruction and other anthropogenic *** the same time,the lack of centralized distribution of wild rice has hampered the sharing of basic information on wild rice resources and the utilization and conservation of wild rice in each country,as well as collaboration among scientists.

关键词： germplasm breeding crops

Integrated Single-cell Multiomic Analysis of HIV Latency Reversal Reveals Novel Regulators of Viral Reactivation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Genomics, Proteomics & Bioinformatics 2024年第1期22卷 67-88页

作者： Manickam Ashokkumar wenwen Mei Jackson J.peterson Yuriko Harigaya David M.Murdoch David M.Margolis Caleb Kornfein Alex Oesterling Zhicheng Guo Cynthia D.Rudin Yuchao Jiang Edward P.Browne Department of Medicine University of North Carolina at Chapel HillChapel HillNC 27599USA HIV Cure Center University of North Carolina at Chapel HillChapel HillNC 27599USA Department of Biostatistics University of North Carolina at Chapel HillChapel HillNC 27599USA Department of Microbiology and Immunology University of North Carolina at Chapel HillChapel HillNC 27599USA Department of Genetics University of North Carolina at Chapel HillChapel HillNC 27599USA Department of Medicine Duke UniversityDurhamNC 27708USA Department of Computer Science Duke UniversityDurhamNC 27708USA Department of Statistics Texas A&M UniversityCollege StationTX 77843USA Department of Biology Texas A&M UniversityCollege StationTX 77843USA Department of Biomedical Engineering Texas A&M UniversityCollege StationTX 77843USA

Despite the success of antiretroviral therapy,human immunodeficiency virus(HIV)cannot be cured because of a reservoir of latently infected cells that evades *** understand the mechanisms of HIV latency,we employed an integrated single-cell RNA sequencing(scRNA-seq)and single-cell assay for transposase-accessible chromatin with sequencing(scATAC-seq)approach to simultaneously profile the transcriptomic and epigenomic characteristics of~125,000 latently infected primary CD4^(+)T cells after reactivation using three different latency reversing *** expressed genes and differentially accessible motifs were used to examine transcriptional pathways and transcription factor(TF)activities across the cell *** identified cellular transcripts and TFs whose expression/activity was correlated with viral reactivation and demonstrated that a machine learning model trained on these data was 75%-79%accurate at predicting viral ***,we validated the role of two candidate HIV-regulating factors,FOXP1 and GATA3,in viral *** data demonstrate the power of integrated multimodal single-cell analysis to uncover novel relationships between host cell factors and HIV latency.

关键词： HIV latency reversal Primary CD4þT cell Single-cell multiomics HIV-regulating factor Machine learning

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

铁路牵引电动机及其车轴支承轴承

国外铁道机车与动车 1985年第10期 32-34+47页

作者： David w.peterson 朱珸

发明的背景本发明是关于铁路牵引电动机和这种电机在车轴上的支承轴承。较详尽地改进了轴支承轴承的安装,使铁路牵引电机轴承结构具有新颖的型式,包括如何安装并保持轴承于其需要的组装位置的方法。广泛使用于铁路牵引电动机的布置方法... 详细信息

发明的背景本发明是关于铁路牵引电动机和这种电机在车轴上的支承轴承。较详尽地改进了轴支承轴承的安装,使铁路牵引电机轴承结构具有新颖的型式,包括如何安装并保持轴承于其需要的组装位置的方法。广泛使用于铁路牵引电动机的布置方法,例如在电力传动内燃机车上,通常是把各台牵

关键词：支承轴承剖分轴承盖牵引电动机车轴车辆轴铁路铁道

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

松针枯病

国外林业 1986年第4期 31-32页

作者： Clenn w.peterson 郭廷举

松针枯病是松类的一种分布广泛、毁坏针叶的病害。它是由松穴褥菌(Dothist-roma pini)引起的。由于该病原菌的危害而导致松树提前落叶,尤其严重地是在大草原东部各州致使西黄松(Pinus ponderos)的造林完全失败。在中部和南部的圣诞树、... 详细信息

松针枯病是松类的一种分布广泛、毁坏针叶的病害。它是由松穴褥菌(Dothist-roma pini)引起的。由于该病原菌的危害而导致松树提前落叶,尤其严重地是在大草原东部各州致使西黄松(Pinus ponderos)的造林完全失败。在中部和南部的圣诞树、防护林带和风景林,该病原菌危害奥地利黑

关键词：针枯病美国生活史侵染针叶人工林苗圃美利坚合众国北美洲奥地利黑松松针褐斑病病原菌分生抱子西黄松美国黄松

Glutamate triggers the expression of functional ionotropic and metabotropic glutamate receptors in mast cells

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2021年第10期18卷 2383-2392页

作者： Md Abdul Alim Mirjana Grujic Paul w.Ackerman Per Kristiansson Pernilla Eliasson Magnus peterson Gunnar Pejler Department of Public Health and Caring Sciences General Medicine and Preventive MedicineUppsala UniversityUppsalaSweden Department of Medical Biochemistry and Microbiology Uppsala UniversityUppsalaSweden Department of Molecular Medicine and Surgery Karolinska InstituteStockholmSweden Department of Orthopedics and Sports Medicine Linköping UniversityLinköpingSweden Academic Primary Health Care UppsalaSweden Department of Anatomy Physiology and BiochemistrySwedish University of Agricultural SciencesUppsalaSweden

Mast cells are emerging as players in the communication between peripheral nerve endings and cells of the immune ***,it is not clear the mechanism by which mast cells communicate with peripheral *** previously found that mast cells located within healing tendons can express glutamate receptors,raising the possibility that mast cells may be sensitive to glutamate *** evaluate this hypothesis,we stimulated primary mast cells with glutamate and showed that glutamate induced the profound upregulation of a panel of glutamate receptors of both the ionotropic type(NMDAR1,NMDAR2A,and NMDAR2B)and the metabotropic type(mGluR2 and mGluR7)at both the mRNA and protein *** binding of glutamate to glutamate receptors on the mast cell surface was ***,glutamate had extensive effects on gene expression in the mast cells,including the upregulation of proinflammatory components such as IL-6 and *** also induced the upregulation of transcription factors,including Egr2,Egr3 and,in particular,*** extensive induction of FosB was confirmed by immunofluorescence *** receptor antagonists abrogated the responses of the mast cells to glutamate,supporting the supposition of a functional glutamate–glutamate receptor axis in mast ***,we provide in vivo evidence supporting a functional glutamate–glutamate receptor axis in the mast cells of injured ***,these findings establish glutamate as an effector of mast cell function,thereby introducing a novel principle for how cells in the immune system can communicate with nerve cells.

关键词： Glutamate Glutamate receptors Mast cells NMDA receptors Tryptase