检索结果-南通市图书馆

Ru/NC heterointerfaces boost energy-efficient production of green H_(2)over a wide pH range

Nano Research 2022年第6期15卷 5134-5142页

作者： Qifeng Yang Botao Zhu Feng Wang Cunjin Zhang Jiahao Cai Peng Jin Lai Feng Soochow Institute for Energy and Materials Innovation(SIEMIS) School of EnergySoochow UniversitySuzhou 215006China School of Materials Science and Engineering Hebei University of TechnologyTianjin 300130China

Green hydrogen(H_(2))is an import energy carrier due to the zero-carbon emission in the energy cycle.Nevertheless,green H_(2)production based on electrolyzer and photovoltaics(EZ/PV)remains limited due to the highly pH-dependant and energy exhausting overall water splitting.Herein,we report a series of Ru-nanocluster-modified mesoporous nanospheres(Rux@mONC)as pH-universal electrocatalysts towards both hydrogen evolution reaction(HER)and hydrazine oxidation reaction(HzOR).The optimal catalyst Ru_(2)0@mONC realizes remarkable catalytic activity and stability towards both HER and HzOR regardless of electrolytes.As a result,the electrode pair of Ru_(2)0@mONC//Ru_(2)0@mONC requires low cell-potentials of 39/429,405/926,and 164/1,141 mV to achieve the current density of 10/100 mA·cm^(−2),as well as the long-term stability for HzOR assisted electrochemical water splitting in alkaline,acidic,and neutral media,respectively.Those performances are more promising compared to the state-of-the-art electrocatalysts so far reported.A proof-of-concept test demonstrates an efficient production of green H_(2)powered by a single-junction silicon solar cell,which may inspire the use of a cost-effective EZ/PV system.Furthermore,a combined spectroscopic and theoretical study verifies the formation of abundant Ru/NC heterointerfaces in Ru_(2)0@mONC,which not only contributes to the balancing of H*adsorption/desorption in HER but also facilitates the*N_(2)H_(2)dehydrogenation in HzOR.

关键词： energy-efficient hydrogen production hydrazine oxidation heterointerface dehydrogenation photovoltaicselectrochemistry coupling

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Configuration Design and Kinematic Performance Analysis of a Novel 4-DOF Parallel Ankle Rehabilitation Mechanism with Two Virtual Motion Centers

引用

Chinese Journal of Mechanical Engineering 2023年第6期36卷 87-104页

作者： Jingke Song Jun Wei Bin Yu Chenglei Liu cunjin Ai Jianjun zhang School of Mechanical Engineering Hebei University of TechnologyTianjin 300401China Hebei Provincial Key Laboratory of Robot Perception and Human-Machine Fusion Tianjin 300130China Intelligent Rehabilitation Device and Detection Technology Engineering Research Center of the Ministry of Education Tianjin 300130China

Aiming at the problem that the existing ankle rehabilitation robot is difficult to fully fit the complex motion of human ankle joint and has poor human-machine motion compatibility,an equivalent series mechanism model that is highly matched with the actual bone structure of the human ankle joint is proposed and mapped into a parallel rehabilita-tion mechanism.The parallel rehabilitation mechanism has two virtual motion centers(VMCs),which can simulate the complex motion of the ankle joint,adapt to the individual differences of various patients,and can meet the reha-bilitation needs of both left and right feet of patients.Firstly,based on the motion properties and physiological structure of the human ankle joint,the mapping relationship between the rehabilitation mechanism and ankle joint is determined,and the series equivalent model of the ankle joint is established.According to the kinematic and con-straint properties of the ankle equivalent model,the configuration design of the parallel ankle rehabilitation robot is carried out.Secondly,according to the intersecting motion planes theory,the full-cycle mobility of the mechanism is proved,and the continuous axis of the mechanism is judged based on the constraint power and its derivative.Then,the kinematics of the parallel ankle rehabilitation robot is analyzed.Finally,based on the OpenSim biomechanical soft-ware,a human-machine coupling rehabilitation simulation model is established to evaluate the rehabilitation effect,which lays the foundation for the formulation of a rehabilitation strategy for the later prototype.

关键词： Ankle rehabilitation robot Double-VMCs mechanism Kinematic performance Human-machine rehabilitation simulation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A novel SIRT6 activator ameliorates neuroinflammation and ischemic brain injury via EZH2/FOXC1 axis

引用

Acta Pharmaceutica Sinica B 2021年第3期11卷 708-726页

作者： Tailin He Jialin Shang Chenglong Gao Xin Guan Yingyi Chen Liwen Zhu Luyong zhang Cunjin Zhang Jian zhang Tao Pang State Key Laboratory of Natural Medicines Jiangsu Key Laboratory of Drug ScreeningJiangsu Key Laboratory of Drug Discovery for Metabolic DiseasesChina Pharmaceutical UniversityNanjing 210009China Medicinal Bioinformatics Center Shanghai Jiao Tong University School of MedicineShanghai 200025China Department of Neurology of Drum Tower Hospital Medical School and the State Key Laboratory of Pharmaceutical BiotechnologyNanjing UniversityNanjing 210008China

Ischemic stroke is the second leading cause of death worldwide with limited medications and neuroinflammation was recognized as a critical player in the progression of stroke,but how to control the overactive neuroinflammation is still a long-standing challenge.Here,we designed a novel SIRT6 activator MDL-811 which remarkably inhibited inflammatory response in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages and primary mouse microglia,which were abolished by silencing SIRT6.RNA-seq screening identified the forkhead box C1 (Foxc1) is a key gene evoked by MDL-811stimulation and is required for the anti-inflammatory effects of MDL-811.We found MDL-811-activated SIRT6 directly interacted with enhancer of zeste homolog 2 (EZH2) and promoted deacetylation of EZH2 which could bind to the promoter of Foxc1 and upregulate its expression to modulate inflammation.Moreover,our data demonstrated that MDL-811 not only ameliorated sickness behaviors in neuroinflammatory mice induced by LPS,but also markedly reduced the brain injury in ischemic stroke mice in addition to promoting long-term functional recovery.Importantly,MDL-811 also exhibited strong anti-inflammatory effects in human monocytes isolated from ischemic stroke patients,underlying an interesting translational perspective.Taken together,MDL-811 could be an alternative therapeutic candidate for ischemic stroke and other brain disorders associated with neuroinflammation.

关键词： SIRT6 activator Neuroinflammation Ischemic stroke Deacetylation Microglia Macrophage FOXC1 EZH2

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

CW-YOLO: joint learning for mask wearing detection in low-light conditions

引用

Frontiers of Computer Science 2023年第6期17卷 191-193页

作者： Mingqiang GUO Hongting SHENG Zhizheng zhang Ying HUANG Xueye CHEN cunjin WANG Jiaming zhang School of Computer Science China University of GeosciencesWuhan 430074China National Engineering Research Center of Geographic Information System Wuhan 430074China Wuhan Zondy Cyber Technology Co.Ltd. Wuhan 430074China Shenzhen Data Management Center of Planning and Natural Resources Shenzhen 518000China Key Laboratory of Urban Land Resources Monitoring and Simulation(Ministry of Natural Resources) Shenzhen 518000China College of Engineering Boston UniversityBoston 02215USA

1 Introduction With the rapid progress of Artificial Intelligence(AI)technology in object detection and face recognition,deep learning methods for face mask wearing detection have become increasingly mature and continuously take into account the needs of efficiency and accuracy.However,these conventional detection methods mostly ignore the complexity of real-world application scenarios,such as extremely darkness and gloomy weather.These unfavorable conditions lead to a series of image degradations that seriously hamper machine vision tasks.Although camera parameter adjustment,auxiliary lighting,or pre-processing enhancement[1]can weaken these negative effects to some extent to promote the detection,they will also result in increased hardware and time costs.

关键词： hardware lighting weather

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effect of the Filling Liquid Ratio on the Thermal Performance of a Novel Thermal Diode with Wick

引用

Journal of Thermal Science 2024年第2期33卷 396-407页

作者： LI Zhiyong MING Tingzhen zhang Heyu ZHAO Sitong WANG Qinggang CAI cunjin YIN Kui FANG Yueping WU Yongjia School of Civil Engineering and Architecture Wuhan University of TechnologyWuhan430070China Sanya Science and Education Innovation Park Wuhan University of TechnologySanya572004China Deparment of Four Station Logistics AcademyXuzhou221000China School of Energy Construction and EnvironmentCoventry UniversityPriory StreetCoventryCV15FBUK

The application of thermal diodes,which allow heat to flow more readily in one direction than the other,is an important way to reduce energy consumption in buildings and enhance the battery heat dissipation of electric vehicles.Depending on various factors including the specific design,materials used,and operating conditions,the convective thermal diode can exhibit the best thermal rectification effect in intended applications compared to the other thermal diodes.In this study,a novel convective thermal diode with a wick was proposed based on the phase change heat transfer mechanism.This design takes advantage of both capillary forces provided by the wick and gravity to achieve enhanced unidirectional heat transfer performance for the designed convective thermal diode.The effect of the filling liquid ratio on the thermal performance of the thermal diode was experimentally investigated,which was in good agreement with the theoretical analysis.The research findings showed that with an optimal liquid filling ratio of 140%,the thermal diode with a wick can achieve a better thermal rectification ratio when subjected to a lower heating power,and the maximum thermal rectification ratio of 21.76 was experimentally achieved when the heating power of the thermal diode was 40 W.

关键词： filling liquid ratio thermal diode wick structure gravity

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Clinical and immune response characteristics among vaccinated persons infected with SARS-CoV-2 delta variant:a retrospective study

引用

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2022年第11期23卷 899-914页

作者： cunjin WANG Yong LI Yuchen PAN Luojing ZHOU Xi zhang Yan WEI Fang GUO Yusheng SHU Ju GAO Department of Anesthesiology Northern Jiangsu People's HospitalYangzhou 225001China Clinical Medical College Yangzhou UniversityYangzhou 225001China Department of Neurology Jiangsu Provincial Corps HospitalChinese People's Armed Police ForceYangzhou 225000China Department of Traditional Chinese Medicine Northern Jiangsu People's HospitalYangzhou 225001China Department of Cardiothoracic Surgery Northern Jiangsu People's HospitalYangzhou 225001China

Objective:This study aimed to observe the clinical and immune response characteristics of vaccinated persons infected with the delta variant of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)in Yangzhou,China.Methods:We extracted the medical data of 129 patients with delta-variant infection who were admitted to Northern Jiangsu People’s Hospital(Yangzhou,China)between August and September,2021.The patients were grouped according to the number of vaccine doses received into an unvaccinated group:a one-dose group and a two-dose group.The vaccine used was SARS-CoV-2-inactivated vaccine developed by Sinovac.We retrospectively analyzed the patients’epidemiological,clinical,laboratory,and imaging data.Results:Almost all patients with delta-variant infection in Yangzhou were elderly,and patients with severe/critical illness were over 70 years of age.The rates of severe/critical illness(P=0.006),fever(P=0.025),and dyspnea(P=0.045)were lower in the two-dose group than in the unvaccinated group.Compared to the unvaccinated group,the two-dose group showed significantly higher lymphocyte counts and significantly lower levels of C-reactive protein(CRP),interleukin-6(IL-6),and D-dimer during hospitalization and a significantly higher positive rate of immunoglobulin G(IgG)antibodies at admission(all P<0.05).The cumulative probabilities of hospital discharge and negative virus conversion were also higher in the two-dose group than in the unvaccinated group(P<0.05).Conclusions:Two doses of the SARS-CoV-2-inactivated vaccine were highly effective at limiting symptomatic disease and reducing immune response,while a single dose did not seem to be effective.

关键词： Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) Delta variant Vaccine Hospitalization Immune response

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

基于系统结构再造的芯片制造技术集成创新机理研究

引用

科技进步与对策 2022年第5期39卷 11-21页

作者：张贝贝李娜李存金北京理工大学管理与经济学院北京100081

芯片制造技术攻关是国家发展战略的迫切需求,提升该类技术自主创新水平是扭转我国集成电路产业核心技术受制于人的关键。以技术系统结构变化为切入点,基于结构再造原理,构建芯片制造技术集成创新机理理论框架,并以芯片光刻工艺专利数据... 详细信息

芯片制造技术攻关是国家发展战略的迫切需求,提升该类技术自主创新水平是扭转我国集成电路产业核心技术受制于人的关键。以技术系统结构变化为切入点,基于结构再造原理,构建芯片制造技术集成创新机理理论框架,并以芯片光刻工艺专利数据为例进行实证研究。结果发现:①系统结构再造是实现技术集成创新的一种有效途径,在技术市场需求引导下,调整或重构芯片制造技术系统中技术元素之间的线性或非线性集成规则,使系统各部分间的关系更加协调、相互配合更加高效,从而推动原技术系统向高良品率、高集成度和低能耗芯片制造新技术系统转变;②芯片制造技术系统结构变化包括技术元素种类变化、元素间关联关系变化和元素比重变化3种原因;③根据系统结构变化程度,将结构再造分成结构调整和结构重组两类。该结论有助于加深相关企业和技术人员对芯片制造技术创新原理的理解,同时对复杂技术系统创新实践具有重要借鉴意义。

关键词：系统结构再造芯片制造技术集成创新

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

新型金属-摩擦阻尼器试验研究及数值分析

引用

地震工程与工程振动 2023年第1期43卷 197-206页

作者：张存金田磊田石柱苏州科技大学江苏省结构工程重点实验室江苏苏州215011 中亿丰工程研究院(苏州)有限公司江苏苏州215131

传统的屈曲约束支撑通常被设计为在大震作用中消耗能量,小震作用下为该结构提供了抗侧刚度。为了克服这一缺点,结合屈曲约束支撑和长圆孔摩擦阻尼器的工作原理,提出了一种基于屈曲约束支撑和长圆孔摩擦阻尼器串联的新型阻尼器,对该阻尼... 详细信息

传统的屈曲约束支撑通常被设计为在大震作用中消耗能量,小震作用下为该结构提供了抗侧刚度。为了克服这一缺点,结合屈曲约束支撑和长圆孔摩擦阻尼器的工作原理,提出了一种基于屈曲约束支撑和长圆孔摩擦阻尼器串联的新型阻尼器,对该阻尼器进行了低周反复荷载试验,分析了其滞回性能、刚度退化等。试验结果表明:新型金属-摩擦阻尼器滞回曲线饱满,通过设置不同的螺栓预紧力可以使阻尼器达到分阶段能耗的目标。利用ABAQUS数值仿真软件对新型金属-摩擦阻尼器进行了数值分析准确性验证。并通过改变模拟试件屈服比例值,了解屈服比例变化对新型金属-摩擦阻尼器抗震性能的影响。结果表明:数值模拟滞回曲线与试验曲线基本一致;屈服比例的增加对阻尼器刚度退化、滑动承载力有明显影响。

关键词：屈曲约束支撑长圆孔摩擦阻尼器新型金属-摩擦阻尼器低周往复荷载试验数值模拟

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Lysosomal Hydrolase Cathepsin D Non-proteolytically Modulates Dendritic Morphology in Drosophila

引用

Neuroscience Bulletin 2020年第10期36卷 1147-1157页

作者： Ting zhang Daxiao Cheng cunjin Wu Xingyue Wang Qiang Ke Huifang Lou Liya Zhu Xiao-Dong Wang Shumin Duan Yi-Jun Liu Department of Neurobiology Key Laboratory of Medical Neurobiology of the Ministry of Health of ChinaZhejiang Province Key Laboratory of NeurobiologyZhejiang University School of MedicineHangzhou 310058China Department of Diagnostics Hangzhou Normal University Medical SchoolHangzhou 311121China Department of Laboratory Medicine Hangzhou Normal University Affiliated HospitalHangzhou 310015China Department of Psychiatry Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310016China Mental Health Center Zhejiang University School of MedicineHangzhou 310058China

The main lysosomal protease cathepsin D(cathD)is essential for maintaining tissue homeostasis via its degradative function,and its loss leads to ceroid accumulation in the mammalian nervous system,which results in progressive neurodegeneration.Increasing evidence implies non-proteolytic roles of cathD in regulating various biological processes such as apoptosis,cell proliferation,and migration.Along these lines,we here showed that cathD is required for modulating dendritic architecture in the nervous system independent of its traditional degradative function.Upon cathD depletion,class I and class III arborization(da)neurons in Drosophila larvae exhibited aberrant dendritic morphology,including overbranching,aberrant turning,and elongation defects.Reintroduction of wild-type cathD or its proteolyticallyinactive mutant dramatically abolished these morphological defects.Moreover,cathD knockdown also led to dendritic defects in the adult mushroom bodies,suggesting that cathD-mediated processes are required in both the peripheral and central nervous systems.Taken together,our results demonstrate a critical role of cathD in shaping dendritic architecture independent of its proteolytic function.

关键词： Cathepsin D Dendritic arborization Sensory neuron Mushroom body Actin Drosophila

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

芯片制造技术的国际竞争态势及企业创新特征——以专利为视角

引用

科技管理研究 2021年第22期41卷 24-35页

作者：张贝贝李存金北京理工大学管理与经济学院北京100081

以专利为视角分析芯片制造领域的国际竞争态势,探索各国核心企业的技术竞争策略和创新模式,以期对中国芯片制造相关领域技术发展提供参考。首先通过聚类和共现等方式识别出芯片制造领域的关键技术,分析该领域的国际竞争格局;然后对芯片... 详细信息

以专利为视角分析芯片制造领域的国际竞争态势,探索各国核心企业的技术竞争策略和创新模式,以期对中国芯片制造相关领域技术发展提供参考。首先通过聚类和共现等方式识别出芯片制造领域的关键技术,分析该领域的国际竞争格局;然后对芯片制造领域核心企业的竞争演化和技术距离进行分析,归纳不同国家核心企业的技术竞争策略和技术创新模式。研究得出:(1)芯片制造关键技术领域的主要竞争国家为美国、日本、韩国、德国、荷兰、中国和法国,具有最高技术水平的国家是日本和美国。(2)中国在芯片制造领域的明星企业是中芯国际集成电路制造公司和台湾积体电路制造公司,前者的竞争对手主要为美国国际商业机器公司和美国瓦特洛电气公司。(3)芯片制造领域核心企业的技术竞争策略表现出明显的国别特征,日本企业更注重专业化,美国明星企业更替更频繁,韩国企业专利布局范围更广泛。(4)不同国家芯片制造核心企业的技术创新模式有所不同,日本企业偏重模仿式创新与突破式创新相结合,韩国企业注重突破式创新,美国企业以突破式创新为主、模仿式创新为辅,中国企业以模仿式创新为主、突破式创新为辅。最后对中国芯片制造技术发展提出建议:政府加大对明星企业的激励和扶持力度、从制度设计层面加强对中国薄弱领域的重视,企业在制定技术创新策略时结合中国情境和自身实际、了解掌握竞争对手的技术现状和创新模式等。

关键词：芯片制造芯片技术专利核心企业技术竞争策略技术创新模式

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：