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Direct measurement and theoretical prediction model of interparticle adhesion force between irregular planetary regolith particles

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International Journal of Mining Science and Technology 2023年第11期33卷 1425-1436页

作者： Heping Xie Qi Wu Yifei Liu Yachen Xie Mingzhong Gao cunbao Li State Key Laboratory of Intelligent Construction and Healthy Operation and Maintenance of Deep Underground Engineering Shenzhen UniversityShenzhen 518060China Guangdong Provincial Key Laboratory of Deep Earth Sciences and Geothermal Energy Exploitation and Utilization Shenzhen UniversityShenzhen 518060China Department of Civil&Mineral Engineering University of TorontoToronto M5S 1A1Canada

Interparticle adhesion force has a controlling effect on the physical and mechanical properties of planetary regolith and *** current research on the adhesion force of planetary regolith and rock particles has been primarily based on the assumption of smooth spherical particles to calculate the intergranular adhesion force;this approach lacks consideration for the adhesion force between irregular shaped *** our study,an innovative approach was established to directly measure the adhesion force between the arbitrary irregular shaped particles;the probe was modified using simulated lunar soil particles that were a typical representation of planetary *** experimental results showed that for irregular shaped mineral particles,the particle size and mineral composition had no significant influence on the interparticle adhesion force;however,the complex morphology of the contact surface predominantly controlled the adhesion *** the contact surface roughness increased,the adhesion force gradually decreased,and the rate of decrease gradually slowed;these results were consistent with the change trend predicted via the theoretical models of quantum ***,a theoretical model to predict the adhesion force between the irregular shaped particles was constructed based on Rabinovich’s theory,and the prediction results were correlated with the experimental measurements.

关键词： Planetary regolith Adhesion force Particle morphology Prediction model

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Experimental study on the mechanical and failure behaviors of deep rock subjected to true triaxial stress:A review

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International Journal of Mining Science and Technology 2022年第5期32卷 915-950页

作者： Heping Xie Jun Lu cunbao Li Minghui Li Mingzhong Gao Guangdong Provincial Key Laboratory of Deep Earth Sciences and Geothermal Energy Exploitation and Utilization College of Civil and Transportation EngineeringShenzhen UniversityShenzhen 518000China Shenzhen Key Laboratory of Deep Underground Engineering Science and Green Energy Shenzhen UniversityShenzhen 518000China Institute of Deep Earth Sciences and Green Energy Shenzhen UniversityShenzhen 518000China

It has become an inevitable trend of human development to seek resources from the deep ***,rock encountered in deep underground engineering is usually in an anisotropic stress state(σ_(1)>σ>σ_(3))due to the influences of geological structures and engineering *** is therefore essential to study the mechanical,seepage,and dynamic disaster behaviors of deep rock under true triaxial stress to ensure the safe operation of deep rock engineering and the efficient exploitation of deep *** recent years,experimental techniques and research on true triaxial rock mechanics have achieved fruitful results that have promoted the rapid development of deep rock mechanics;thus,it is necessary to systematically review and summarize these *** work first introduced several typical true triaxial testing apparatus and then reviewed the corresponding research progress on rock deformation,strength,failure mode,brittleness,and energy as well as the 3D volumetric fracturing(dynamic disaster)properties of deep rocks under true triaxial ***,several commonly used true triaxial rock strength criteria and their applicability,the permeability characteristics and mathematical models of deep reservoir rocks,and the disaster-causing processes and mechanisms of disturbed volumetric fracturing(rockburst,compound dynamic disasters)in deep rock engineering were *** work may provide an essential reference for addressing the true triaxial rock mechanics issues involved in deep rock engineering,especially regarding the stability of surrounding rock at depth,disaster prevention and control,and oil and gas exploitation.

关键词： True triaxial stress Deep rock mass Mechanical properties Strength criterion Permeability characteristics Dynamic disaster

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System Reliability Analysis for Truss Structures Based on Automatic Updated Model

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Computer Modeling in Engineering & Sciences 2023年第3期134卷 2057-2071页

作者： Pengyu Chen cunbao Zhao He Yao Junliang Li State Key Laboratory of Mechanical Behavior and System Safety of Traffic Engineering Structures Shijiazhuang Tiedao UniversityShijiazhuang050043China

Multiple failure modes tend to be identified in the reliability analysis of a redundant truss *** identification process involves updating the model for identifying the next potential failure *** we intend to update the finite element model automatically in the identification process of failure modes and further perform the system reliability analysis *** study presents a framework that is implemented through the joint simulation of MATLAB and APDL and consists of three parts:reliability index of a single member,identification of dominant failure modes,and system-level reliability analysis for system reliability analysis of truss ***,RSM(response surface method)combines with a constrained optimization model to calculate the reliability indices *** theβ-unzipping method is adopted to identify the dominant failuremodes,and the system function in MATLAB,as well as the EKILL command in APDL,is used to facilitate the automatic update of the finite element model and realize ***,the differential equivalence recursion algorithmis performed to approximate the reliability indices of failuremodes efficiently and ***,the PNET(probabilistic network evaluation technique)is used to calculate the joint failure probability as well as the system reliability *** illustrative examples demonstrate the accuracy and efficiency of the proposed system reliability analysis framework through comparison with corresponding references.

关键词： Multiple failure modes truss structure automatic update system reliability analysis framework

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深部煤层注气强化开采的流-固-热耦合数值模拟研究

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煤矿安全 2024年第7期55卷 31-38页

作者：姚文军邓存宝范楠申文迈张林峰张鹏莉太原理工大学安全与应急管理工程学院山西太原030024

为研究温度效应对深部煤层注CO_(2)增抽瓦斯的影响规律,根据煤体变形特征和瓦斯渗流特性基本理论,建立了同时考虑非等温吸附、二元气体竞争吸附、气体渗流和扩散、热传递和热对流的注CO_(2)强化煤层抽采的流-固-热耦合模型,探究了温度... 详细信息

为研究温度效应对深部煤层注CO_(2)增抽瓦斯的影响规律,根据煤体变形特征和瓦斯渗流特性基本理论,建立了同时考虑非等温吸附、二元气体竞争吸附、气体渗流和扩散、热传递和热对流的注CO_(2)强化煤层抽采的流-固-热耦合模型,探究了温度效应对煤储层参数和产气演化规律的影响。结果表明:煤层温度降低引起的煤基质收缩促进了CH4解吸,忽略温度效应的流-固耦合模型会低估瓦斯产气量;在初始渗透率为3.95×10^(-17) m^(2),CO_(2)注气压力为8 MPa时,对于韩城矿区3#煤层埋深1400 m的深部煤体而言,考虑温度效应(319.5 K)的流-固-热耦合模型相比流-固耦合模型,瓦斯抽采3650 d,煤层平均瓦斯压力下降0.69%,A点渗透率增幅11.02%,产气速率增幅13.51%,累计产气量增幅13.76%。

关键词：瓦斯抽采流-固-热耦合煤层注CO2气体煤层气绝对渗透率

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LNP-CpG ODN-adjuvanted varicella-zoster virus glycoprotein E induced comparable levels of immunity with Shingrix^(TM) in VZV-primed mice

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Virologica Sinica 2022年第5期37卷 731-739页

作者： Ning Luan Han Cao Yunfei Wang Kangyang Lin cunbao Liu Institute of Medical Biology Chinese Academy of Medical Sciences and Peking Union Medical CollegeKunming 650118China

Latent varicella-zoster virus(VZV)may be reactivated to cause herpes zoster,which affects one in three people during their *** currently available subunit vaccine Shingrix^(TM) is superior to the attenuated vaccine Zostavax®in terms of both safety and efficacy,but the supply of its key adjuvant component QS21 is *** ionizable lipid nanoparticles(LNPs)that were recently approved by the FDA for COVID-19 mRNA vaccines as carriers,and oligodeoxynucleotides containing CpG motifs(CpG ODNs)approved by the FDA for a subunit hepatitis B vaccine as immunostimulators,we developed a LNP vaccine encapsulating VZV-glycoprotein E(gE)and CpG ODN,and compared its immunogenicity with Shingrix^(TM) in C57BL/6J *** results showed that the LNP vaccine induced comparable levels of gE-specific IgG antibodies to Shingrix^(TM) as determined by enzymelinked immunosorbent assay(ELISA).Most importantly,the LNP vaccine induced comparable levels of cellmediated immunity(CMI)that plays decisive roles in the efficacy of zoster vaccines to Shingrix^(TM) in a VZVprimed mouse model that was adopted for preclinical studies of Shingrix^(TM) .Number of IL-2 and IFN-γsecreting splenocytes and proportion of T helper 1(Th1)cytokine-expressing CD4^(+)T cells in LNP-CpG-adjuvanted VZV-gE vaccinated mice were similar to that of Shingrix^(TM) boosted *** of the components in this LNP vaccine can be artificially and economically synthesized in large quantities,indicating the potential of LNP-CpGadjuvanted VZV-gE as a more cost-effective zoster vaccine.

关键词： Varicella zoster virus(VZV) Subunit vaccine Adjuvant Lipid nanoparticle(LNP) CpG oligodeoxynucleotide(CpG ODN) AS01B Humoral immunity Cell-mediated immunity(CMI)

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煤岩体系微观组分及孔隙结构对甲烷吸附的影响研究

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矿业安全与环保 2024年第1期51卷 51-60,69页

作者：周晋辉郭晓阳赵博金智新邓存宝刘继勇王蒙太原理工大学安全与应急管理工程学院山西太原030024 中联煤层气有限责任公司北京100011 华阳新材料科技集团有限公司博士后工作站山西阳泉045000

为了探究煤岩体系微观组分及孔隙结构对甲烷吸附的影响规律,选取沙曲一矿6组煤岩样,通过工业分析、X射线衍射、扫描电镜与能谱分析、低温氮吸附、计算机断层扫描,以及煤岩甲烷吸附实验,分别研究煤岩样微观组分、孔隙结构特征对甲烷吸附... 详细信息

为了探究煤岩体系微观组分及孔隙结构对甲烷吸附的影响规律,选取沙曲一矿6组煤岩样,通过工业分析、X射线衍射、扫描电镜与能谱分析、低温氮吸附、计算机断层扫描,以及煤岩甲烷吸附实验,分别研究煤岩样微观组分、孔隙结构特征对甲烷吸附的影响。研究结果表明:煤样和岩样无机组分质量分数分别为15.82%~20.93%、90.80%~94.68%,均以石英和黏土矿物为主;岩样BET比表面积为3.32~8.70 m^(2)/g、吸附孔体积为0.0095~0.0191 cm^(3)/g,均大于煤样的BET比表面积和吸附孔体积;岩样孔隙表面粗糙度、孔结构复杂度略大于煤样的孔隙表面粗糙度、孔结构复杂度,与黏土矿物含量高有关。煤岩样甲烷等温吸附曲线均符合朗格缪尔模型,可用极限吸附量V_(L)和朗格缪尔压力p_(L)描述吸附规律;相同吸附温度下,岩样存在一定的吸附性,煤样吸附性远大于岩样。分析得出,煤岩样的有机组分含量、黏土矿物含量、表面分形维数、比表面积和吸附孔体积对甲烷吸附过程V_(L)、p_(L)影响显著。基于多元线性回归分析了5种因素对甲烷吸附规律的影响关系:有机组分含量高、比表面积大的样品CH 4分子极限吸附量V_(L)越大,而黏土矿物含量高不利于吸附甲烷;吸附孔体积越小、黏土矿物含量越高、比表面积越大,朗格缪尔压力p_(L)越大。

关键词：煤岩体系微观组分孔隙结构甲烷吸附朗格缪尔模型

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Seismic Geothermal Resource Exploration based on CPU/GPU Collaborative Parallel Prestack Time Migration

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Acta Geologica Sinica(English Edition) 2022年第5期96卷 1742-1751页

作者： LONG Xiting LIU Fei XIE Heping LIN Wenjing LIU Yanguang LI cunbao Shenzhen Key Laboratory of Deep Underground Engineering Sciences and Green Energy Shenzhen UniversityShenzhen 518060China Guangdong Provincial Key Laboratory of Deep Earth Sciences and Geothermal Energy Exploitation and Utilization College of Civil and Transportation EngineeringShenzhen UniversityShenzhen 518060China Sichuan University State Key Lab Hydraul&Mt River EngnChengdu 610065China Institute of Hydrogeology and Environmental Geology Chinese Academy of Geological SciencesShijiazhuang 050061China Sichuan University MOE Key Laboratory of Deep Earth Science and EngineeringChengdu 610065China

Geothermal resources exist in complex and comprehensive geological settings. In the current study, we proposed a CPU/GPU collaborative parallel prestack time migration methodology for geothermal resource exploration. First, seismic geological conditions in Xian County were obtained based on an analysis of drill cores for further seismic evaluation. Then,combined with the analysis of two-dimensional seismic data in the adjacent area, a test section with three seismic survey lines were designed to explore the geological structure of the study area. In the study area, the seismic data were derived through the multiple coverage reflection wave exploration method with explosive ignition in deep wells and high coverage frequency observations. Finally, we employed CPU/GPU collaborative parallel prestack time migration technology to analyze the obtained seismic data for geothermal resource evaluation. The favorable areas of karst fissure heat storage in Middle–Upper Proterozoic Jixianian and Paleozoic Cambrian–Ordovician rocks were inferred together with two preferred recommended exploration holes.

关键词： seismic explosive source geological structure geothermal

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Selection and thermal physical characteristics analysis of in-situ condition preserved coring lunar rock simulant in extreme environment

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International Journal of Mining Science and Technology 2023年第11期33卷 1411-1424页

作者： Haichun Hao Mingzhong Gao cunbao Li Xuan Wang Yan Wu Zheng Gao Wen Yu Xuemin Zhou Guangdong Provincial Key Laboratory of Deep Earth Sciences and Geothermal Energy Exploitation and Utilization Institute of Deep Earth Sciences and Green EnergyCollege of Civil and Transportation EngineeringShenzhen UniversityShenzhen 518060China Shenzhen Key Laboratory of Deep Underground Engineering Sciences and Green Energy Shenzhen UniversityShenzhen 518060China Center for Lunar and Planetary Sciences Institute of GeochemistryChinese Academy of SciencesGuiyang 550081China

With the increasing scarcity of Earth’s resources and the development of space science and technology,the exploration, development, and utilization of deep space-specific material resources(minerals, water ice, volatile compounds, etc.) are not only important to supplement the resources and reserves on Earth but also provide a material foundation for establishing extraterrestrial research bases. To achieve large depth in-situ condition-preserved coring(ICP-Coring) in the extreme lunar environment, first, lunar rock simulant was selected(SZU-1), which has a material composition, element distribution, and physical and mechanical properties that are approximately equivalent to those of lunar mare basalt. Second, the influence of the lunar-based in-situ environment on the phase, microstructure, and thermal physical properties(specific heat capacity, thermal conductivity, thermal diffusivity, and thermal expansion coefficient)of SZU-1 was explored and compared with the measured lunar rock data. It was found that in an air atmosphere, low temperature has a more pronounced effect on the relative content of olivine than other temperatures, while in a vacuum atmosphere, the relative contents of olivine and anorthite are significantly affected only at temperatures of approximately-20 and 200 ℃. When the vacuum level is less than100 Pa, the contribution of air conduction can be almost neglected, whereas it becomes dominant above this threshold. Additionally, as the testing temperature increases, the surface of SZU-1 exhibits increased microcracking, fracture opening, and unevenness, while the specific heat capacity, thermal conductivity,and thermal expansion coefficient show nonlinear increases. Conversely, the thermal diffusivity exhibits a nonlinear decreasing trend. The relationship between thermal conductivity, thermal diffusivity, and temperature can be effectively described by an exponential function(R^(2)>0.98). The research results are consistent with previous studies

关键词： Lunar-based Lunar rock simulant Extreme environment Thermal physical properties

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Stress-unloading and gas migration improvement mechanism in the soft and hard interbedded coal seam using directional hydraulic flushing technology

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International Journal of Mining Science and Technology 2023年第9期33卷 1165-1179页

作者： Hao Zhang Yuanping Cheng cunbao Deng Jingyu Jiang Lei Zhang Xiaoyu Yan Junwei Guo Suifang Wang College of Safety&Emergency Management Engineering Taiyuan University of TechnologyTaiyuan 030024China Datong Coal Mine Group Co. LtdDatong 037037China Key Laboratory of Coal Methane and Fire Control Ministry of EducationChina University of Mining and TechnologyXuzhou 221116China National Engineering Research Center for Coal and Gas Control China University of Mining and TechnologyXuzhou 221116China School of Safety Engineering China University of Mining and TechnologyXuzhou 221116China

To enhance gas drainage in the soft and hard interbedded(SHI)coal seam,it’s necessary to unload the insitu stress and improve its gas migration *** this research,a directional hydraulic flushing(DHF)technology was carried *** stress-unloading and gas migration improvement mechanism was analyzed through numerical simulation,and systematic engineering tests were conducted to verify the gas drainage *** results show that the improvement of gas migration performance in the SHI coal seam is caused by a combined effect of seepage-improving and *** DHF,stress-unloading and plastic failure could be achieved both in the soft coal(SC)sublayer and in the hard coal(HC)***,the gas diffusion capacity improves significantly in the SC sublayer,while the gas seepage capacity improves notably in the HC ***,the stress-unloading and gas migration improvement effect improves with the flushing radius and the thickness of the SC ***,after adopting the DHF technology,the gas drainage effect improved *** borehole number dropped by 49%,the gas drainage ratio increased from 26.0%to 48.2%,and the average coal roadway excavation speed increased from 2.4 to 5.6 m/d.

关键词： Hydraulic flushing Stress-unloading Plastic failure Permeability-increasing Gas migration

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氟伐他汀钠对斑马鱼肝抗氧化体系及肝功能的影响

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实验动物科学 2024年第2期41卷 41-45页

作者：王贤锐牟全玲李小龙史嘉烨李茹萌丁存宝华北理工大学生命科学学院唐山063210

目的研究氟伐他汀钠(FLU)对斑马鱼肝内抗氧化体系和肝功能的影响。方法采用半静态暴露法,以氟伐他汀钠为研究对象,选取斑马鱼为指示生物,将斑马鱼分别暴露在空白对照组和0.004、0.04、0.4 mg/L的氟伐他汀钠溶液中,于暴露48 h后,取样检... 详细信息

目的研究氟伐他汀钠(FLU)对斑马鱼肝内抗氧化体系和肝功能的影响。方法采用半静态暴露法,以氟伐他汀钠为研究对象,选取斑马鱼为指示生物,将斑马鱼分别暴露在空白对照组和0.004、0.04、0.4 mg/L的氟伐他汀钠溶液中,于暴露48 h后,取样检测氟伐他汀钠对斑马鱼肝内ROS含量和抗氧化酶SOD、CAT、GPx、GST的活性,同时检测肝功能指标ALT、AST的活性。结果与对照组相比,氟伐他汀钠暴露48 h后,中、高浓度的氟伐他汀钠会造成ROS含量显著性升高(P<0.01),CAT、SOD、CuZn-SOD、GPx的活性变化具有同步性,但低浓度的氟伐他汀钠对所有的抗氧化酶均无显著的激活或抑制作用。中浓度的氟伐他汀钠对CAT、SOD具有激活作用(P<0.01),高浓度的氟伐他汀钠对抗氧化酶SOD、CAT、GPx、GST都有激活作用(P<0.05,P<0.01),同时对ALT和AST也具有显著性的激活作用(P<0.01)。分子对接结果表明氟伐他汀钠能够与斑马鱼CAT蛋白对接,最佳对接位点为Met392,对接能量为-4.63 kcal/mol。结论随着药物浓度的升高,氟伐他汀钠能够对斑马鱼肝内抗氧化体系和肝功能造成影响。

关键词：氟伐他汀钠斑马鱼抗氧化体系肝功能分子对接

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