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Near-infrared organic lasers with ultra-broad emission bands by simultaneously harnessing four-level and six-level systems

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Chinese Chemical Letters 2024年第8期35卷 288-293页

作者： Lei Wang Jun-Jie Wu Chang-cun Yan Wan-Ying Yang Zong-Lu Che Xin-yu Xia Xue-Dong Wang Liang-Sheng Liao Jiangsu Key Laboratory for Carbon-Based Functional Materials&Devices Institute of Functional Nano&Soft Materials(FUNSOM)Soochow UniversitySuzhou 215123China Jiangsu Engineering Laboratory of Novel Functional Polymeric Materials College of ChemistryChemical Engineering and Materials ScienceSoochow UniversitySuzhou 215123China Macao Institute of Materials Science and Engineering Macao University of Science and TechnologyMacao SAR 999078China

Organic lasers with broad emission bands in near-infrared(NIR)region are crucial for their applications in laser communication,night-vision as well as bioimaging owing to the abundance of selectable lasing ***,for most organic gain materials,gain regions are limited in a small wavelength range because of the fixed energy level ***,we design a strategy to realize NIR organic lasers with broad emission bands based on tunable energy level systems induced by cascaded excited-state intramolecular proton transfer(ESIPT).A novel gain material named DHNN was developed,which can undergo a cascaded double-ESIPT process supporting four-level and six-level systems *** doping DHNN into polystyrene microspheres,NIR lasers with tunable emission bands can be achieved based on the careful modulation of ***,organic lasers with an ultra-broad emission band ranging from 700 nm to 900 nm was successfully achieved by harnessing four-level and six-level systems simultaneously.

关键词： Excited-state intramolecular proton transfer Organic solid-state laser Wide gain interval Near-infrared emission Molecular design

Development of the electric automatic steering system for agricultural vehicles

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International Journal of Agricultural and Biological Engineering 2024年第1期17卷 209-214页

作者： Guangshun An Chong yu juan Du Xiang Yin Youliang Ni Chengqian Jin School of Agricultural Engineering and Food Science Shandong University of TechnologyZibo 255000ShandongChina Nanjing Research Institute for Agricultural Mechanization of Ministry of Agriculture and Rural Affairs Nanjing 210014China

Automatic guidance of agricultural vehicles requires automatic execution of operation commands received from the navigation controller by using electronically controlled mechanisms for wheel steering,speed changing and work *** steering contributes as a prerequisite technique in automatic and semi-automatic agricultural *** research aimed to develop an electric automatic steering system that was compact in its structure and integrated into original steering mechanism in a simply and convenient way for aftermarket modification.A brushless motor and reducer assembly was utilized to provide an adequate steering torque instead of manual maneuver.A rapid assembling approach was proposed by passing the steering shaft through the hollow output shaft.A digital proportional-integral-differential(PID)algorithm was implemented to calculate the rotation speeds and directions by comparing the desired angle and the actual angle,which was implemented in a printed circuit board with a microcontroller unit(MCU)and interface *** unmanned wheeled tractor was applied as test platform to integrate the newly developed electric automatic steering *** were conducted to evaluate its performance in terms of stability and *** autonomous navigation system guided the tractor along target paths in the field by sending steering commands to the electric automatic steering *** results show that the steering angle error was less than 0.81°when desired steering angle was less than 10°.The lateral error difference was no more than 4.76 cm when repeating following the same target path,which indicated that the electric automatic steering system responded accurately and robustly to steering commands.

关键词： automatic steering automatic navigation agricultural vehicles

Robot-assisted treatment of secondary epilepsy caused by parasitic infection:a case report

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Acta Epileptologica 2024年第2期7卷 143-150页

作者： juan Luo Xin Chen Sixun yu Haifeng Shu Department of Neurosurgery Affiliated Hospital of Southwest Medical UniversityLuzhou Sichuan 646000China Department of Neurosurgery General Hospital of the Western Theater Command of the PLAChengdu Sichuan 610083China

Background Cerebral sparganosis represents the most severe manifestation of sparganosis,with a relatively low global *** cases of secondary epileptic seizures caused by sparganosis infection in the functional areas of the brain,what advanced neurosurgical techniques should be employed to precisely identify and excise the epi-leptic lesions in the deep functional areas of the brain,aiming to achieve maximal removal while minimising the risk of neurological deficits?This remains a current challenge for epilepsy *** presentation A 24-year-old Chinese male was admitted to our hospital,presenting with a history of left limb twitching persisting for over a *** main clinical symptoms presented twitching and numbness of his left limb without loss of *** the premise of inappropriate anti-seizure treatment,recurrent epilepsy attacked *** patient’s diagnosis was considered as“space-occupying lesions in the several lobes of brain,secondary epilepsy”after comprehensive assessment and *** experts considered that the patient’s space-occupying lesions in the right frontal and parietal lobes were highly suspected to be infected by *** report delved into the application of neurosurgery robot-assisted frameless stereotaxic technology and intraopera-tive stereotactic electroencephalography(SEEG)monitoring technology to accurately locate and optimize removal of parasite-related epileptic lesions situated in functional areas of the *** a result,the patient had achieved seizure freedom,leaving no symptoms of neurological *** With the highly integrated development of imaging technology,mechanical technology,computer control technology,and artificial intelligence,surgical robots are poised to play a larger role across various neurosur-gical specialties in the *** benefits for patients and the promising application of this technology,its utilization holds significant value.

关键词： Cerebral sparganosis Secondary epilepsy Robot Frameless stereotaxic technology

Molecular Investigation of Theileria in Ixodid Ticks from Changzhi,Shanxi Province,China

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Biomedical and Environmental Sciences 2024年第8期37卷 922-925页

作者： Jia Cui Hua Xiang Rao Yiping Liu Dongmei Li juan yu Department of Microbiology of Basic Medical Sciences Changzhi Medical CollegeChangzhi 046000ShanxiChina Department of Epidemiology and Health Statistics of Public Health and Preventive Medicine Changzhi Medical CollegeChangzhi 046000ShanxiChina Department of Medical parasitology of Basic Medical Sciences Changzhi Medical CollegeChangzhi 046000ShanxiChina Department of Vector Biology and Control National Institute for Communicable Disease Control and PreventionChinese Center for Disease Control and PreventionBeijing 102206China

Theileria is a tick-borne intracellular protozoan that typically parasitizes erythrocytes,lymphocytes,and macrophages and causes acute clinical symptoms in host animals,including high fever,anemia,jaundice,and swelling of superficial lymph nodes[1].Theileriosis can lead to high mortality rates,and its rising global prevalence has resulted in significant economic losses to livestock husbandry and the national economy[2].

关键词： husbandry swelling typically

A Study on Idea Adoption Prediction Model Based on SMOTE-AdaBoost: Taking Salesforce Platform as an Example

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Journal of Systems Science and Information 2024年第4期12卷 476-490页

作者： yunjiang XI Futao HUANG Lu HUANG Xiao LIAO juan yu School of Business Administration South China University of Technology School of Internet Finance and Information Engineering Guangdong University of Finance School of Economics and Management Fuzhou University

In the context of information overload, companies often struggle to effectively identify valuable ideas on their open innovation platforms. In this article, we propose an idea adoption strategy based on machine learning. We used data from a well-known open innovation platform, Salesforce, and extracted characteristic variables using the Information Adoption Model. Four classification models were then constructed based on AdaBoost, Random Forest, SVM and Logistic Regression models. Due to significant differences in the number of positive and negative samples in the OIP, we used the SMOTE method to address the problem of data imbalance. The results of the study showed that the ensemble learning models were more accurate in identifying valuable ideas than the individual machine learning models. When comparing the two ensemble learning models, AdaBoost outperformed Random Forest in predicting both positive and negative class samples. The SMOTE-AdaBoost model achieved a recall of 0.93, a precision of 0.92 and an impressive AUC of 0.98 in identifying adopted ideas, which could well identify valuable ideas and has implications for improving the efficiency and quality of idea adoption in OIP. The shortcoming of this work is that it only investigated a single platform. In the future, we will consider extending this method to different platforms and multiple classification problems.

关键词： open innovation platform AdaBoost information adoption ensemble learning

Factors and Their Impact on Treatment Effect of Acupuncture in Different Outcomes:A Meta-Regression of Acupuncture Randomized Controlled Trials

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Chinese Journal of Integrative Medicine 2024年第3期30卷 260-266页

作者： XIU Wen-cui GANG Wei-juan ZHOU Qi SHI Lan-jun HU Xiang-yu MING Tian-yu LUO Zhen ZHANG yu-qing JING Xiang-hong Institute of Acupuncture and Moxibustion China Academy of Chinese Medical SciencesBeijing100700China China Center for Evidence-Based Traditional Chinese Medicine China Academy of Chinese Medical SciencesBeijing100700China Department of Health Research Methods Evidenceand ImpactMcMaster UniversityHamiltonOntarioL8S 4L8Canada Center for Evidence-Based Integrative Medicine-Clarity Collaboration Guang’anmen HospitalChina Academy of Chinese Medical SciencesBeijing100053China

Background:The effects of acupuncture have varied in different randomized controlled trials(RCTs),and there are many factors that influence treatment effect of acupuncture in different outcomes,with conflicting ***:To identify factors and their impact on the treatment effect of acupuncture in different ***:Acupuncture RCTs were searched from 7 databases including Medline(Pub Med),Embase,Cochrane Central Register of Controlled Trials,China National Knowledge Infrastructure,Wanfang Database,VIP Database,and China Biology Medicine disc between January 1st,2015 and December 31st,*** studies must compare acupuncture to no acupuncture,sham acupuncture,or waiting lists,and report at least 1patient-important outcome.A multi-level meta-regression was conducted using a 3-level robust mixed model and univariate analyses were performed for all independent variables,even those excluded from the multivariable model due to *** used thresholds of 0.2 and 0.4 for the difference of standardized mean differences(SMDs),categorising them as small(0.4) ***:The pain construct analysis involved 211 effect estimates from 153 studies and 14 independent ***-frequency acupuncture treatment sessions produced larger effects compared to low-frequency sessions [large magnitude,the difference of adjusted SMDs 0.46,95% confidence interval(CI) 0.07 to 0.84;P=0.02].The non-pain symptoms construct analysis comprised 323 effect estimates from 231 studies and 15 independent *** acupuncture showed moderately larger effects when compared to non-penetrating acupuncture(0.30,95% CI 0.06 to 0.53;P=0.01).The function construct analysis included 495 effect estimates from 274 studies and 14 independent *** acupuncture and the flexible acupuncture regimen showed moderately larger effects,compared to non-penetrating acupuncture and fixed regimen,respectively(0.40,95% CI 0

关键词： acupuncture randomized controlled trial patient-important outcome meta-regression

Climate-driven changes in drought metrics across the Yellow River Basin based on Coupled Model Intercomparison Project Phase 6

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Journal of Geographical Sciences 2024年第9期34卷 1841-1856页

作者： LIU Jiayuan LIU Xianfeng LIANG juan FENG yu School of Geography and Tourist Shaanxi Normal UniversityXi'an 710119China Ningbo Institute of Digital Twin Eastern Institute for Advanced StudyNingbo 315200ZhejiangChina

Recent climate change has accelerated the global hydrological cycle, substantially affecting drought metrics such as drought duration and drought propagation;however, knowledge of drought patterns in these metrics remains limited. Here, we aimed to address the evolution and influencing factors of major drought metrics under past and future climate scenarios within the Yellow River Basin(YRB) based on Coupled Model Intercomparison Project Phase 6(CMIP6). Accordingly, we investigated the changes in drought duration for meteorological drought and agricultural drought across the YRB and identified the variability in drought propagation time from meteorological drought to agricultural drought by using a standardized precipitation/soil moisture index and run theory. Meteorological and agricultural drought duration, and propagation time, increased from 1850 to 2014, decreased significantly from 2015 to 2100 with change trends of –0.0027, –0.0197, and –0.002 month/year, respectively. Drought duration had a negative sensitivity to humidification, and agricultural drought was more sensitive than meteorological drought. Propagation time exhibited a greater sensitivity to meteorological humidification than agricultural humidification. The results also suggest that precipitation, evapotranspiration, and soil moisture are the main drivers of drought metric changes, with air temperature and crop cover exhibiting a strong indirect effect on drought metrics in the YRB. Decreased propagation time from meteorological to agricultural drought and decreased duration provide evidence for the accelerated occurrence and increased impact of drought, highlighting the importance of a more comprehensive understanding of drought metric changes under rapid climate change.

关键词： drought duration drought propagation climate change humidification Yellow River Basin CMIP6

Promotion and Mechanism of Acupotomy on Chondrocyte Autophagy in Knee Osteoarthritis Rabbits

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Chinese Journal of Integrative Medicine 2024年第9期30卷 809-817页

作者： LU Man MENG De-hong SHE Ze-yu WU Xian XIA Shuai YANG Kai-ning LIU cun-bin LI Tao YANG Yong-hui The First Affiliated Hospital of Anhui University of Chinese Medicine Hefei230031China The Second Affiliated Hospital of Anhui University of Chinese Medicine Hefei230038China Department of Acupotomy Rehabilitation Anhui Provincial Hospital of Integrated Traditional Chinese and Western MedicineHefei230031China

Objective:To explore the effect of acupotomy intervention on autophagy of chondrocytes in rabbits with knee osteoarthritis(KOA),and to determine the possible mechanisms of acupotomy to alleviate cartilage ***:The modified Videman method was used to construct a KOA rabbit *** modeling,40 rabbits were randomly divided into 4 groups by a random number table:control;KOA(model);KOA+acupotomy(acupotomy),and KOA+sham acupotomy(sham),10 in each *** a 3-week treatment course,the knee joint activity was determined by the modified Lequesne MG ***-eosin staining staining was used to examine the morphological changes of *** of chondrocytes was observed by transmission electron *** surface morphology of cartilage tissue was observed by scanning electron *** mRNA and protein levels of AMP kinase/mammalian target of rapamycin/Unc-51(AMPK/mTOR/ULK1)signal pathway key proteins,autophagy-related factor Beclin-1 and microtubule-associated protein 1A/1B light chain 3(LC3)in rabbit knee cartilage were assessed by real-time fluorescence quantitative polymerase chain reaction and Western blot,***:The modified Lequesne MG score of acupotomy group was significantly lower than that of model group(P<0.05).Pathological results showed that chondrocyte autophagy decreased and cartilage surface was rough in the model group,which recovered after acupotomy *** mRNA expressions of AMPK,ULK1,Beclin-1 and the protein levels of p-AMPK,p-ULK1,Beclin-1,and LC3Ⅱ/LC3Ⅰwere decreased in the model group,while the mRNA and protein expressions of mTOR were increased(P<0.01).However,acupotomy treatment reversed these abnormal changes(P<0.05).Conclusions:Acupotomy could effectively up-regulate the expressions of AMPK,ULK1 and Beclin1,reduce the expression of mTOR,promote autophagy,and alleviate joint *** is a promising complementary and alternative therapy for KOA.

关键词： acupotomy knee asteoarthritis autophagy AMPK/mTOR/ULK1 signaling pathway rabbit

Role of angiotensin receptor-neprilysin inhibitor in diabetic complications

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World Journal of Diabetes 2024年第5期15卷 867-875页

作者： Ying Liu cun-yu Lu Yi Zheng yu-Min Zhang Ling-Ling Qian Ku-Lin Li Gary Tse Ru-Xing Wang Tong Liu Department of Cardiology Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular DiseaseTianjin Institute of CardiologySecond Hospital of Tianjin Medical UniversityTianjin 300211China Department of Cardiology Xuzhou No.1 Peoples HospitalXuzhou 221005Jiangsu ProvinceChina Department of Cardiology Wuxi 9^(th)People’s Hospital Affiliated to Soochow UniversityWuxi 214062Jiangsu ProvinceChina Department of Cardiology Wuxi People’s Hospital Affiliated to Nanjing Medical UniversityWuxi 214023Jiangsu ProvinceChina School of Nursing and Health Studies Metropolitan UniversityHong Kong 999077China Kent and Medway Medical School Kent CT27NTCanterburyUnited Kingdom

Diabetes mellitus is a prevalent disorder with multi-system manifestations,causing a significant burden in terms of disability and deaths ***-tensin receptor-neprilysin inhibitor(ARNI)belongs to a class of medications for treating heart failure,with the benefits of reducing hospitalization rates and *** review mainly focuses on the clinical and basic investigations related to ARNI and diabetic complications,discussing possible physiological and molecular mechanisms,with insights for future applications.

关键词： Angiotensin receptor-neprilysin inhibitor Diabetic mellitus Complication