检索结果-南通市图书馆

Oligodendrocyte transcription factor 1 overexpression promotes oligodendrocyte transcription factor 2 expression in the brains of neonatal rats exposed to hypoxia

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2011年第34期6卷 2713-2717页

作者： Lijun yang hong cui Aijun yang Wenxing Jiang Department of Pediatrics Beijing Friendship Hospital Capital Medical University Beijing 100050 China

To examine the expression profiles of oligodendrocyte transcription factors 1 and 2 （Oligl and Olig2） and the interaction between these two proteins, Oligl was transfected into the lateral ventricles of neonatal rats subjected to hypoxia. Immunohistochemistry demonstrated that Olig2 was expressed throughout the nuclei in the brain, and expression increased at 3 days following hypoxia and was higher than levels at 7 days following Ad5-Oligl transfection. Western blot revealed that Oligl and Olig2 expression increased in Oligl-transfected brain cells 3 days after hypoxia, but Oligl and Olig2 expression decreased at 7 days. These results indicate that Oligl overexpression enhances Olig2 expression in brain tissues of hypoxia rats.

关键词： oligodendrocyte transcription factor 1 oligodendrocyte transcription factor 2 hypoxia neonatal rat gene transfection neural regeneration

Rare earth inorganic-organic hybrid compounds based on Keggin-type polyoxometalate {SiW_(12)} with fast-responsive photochromism and switchable luminescence properties

在线全文

学校读者我要写书评

暂无评论

Journal of Rare Earths 2024年第2期42卷 286-292,I0003页

作者： hong cui Yanli yang Xue Bai Xu Han Wensha Zhang Ying Lu Shuxia Liu Key Laboratory of Polyoxometalate and Reticular Material Chemistry of the Ministry of Education College of ChemistryNortheast Normal UniversityChangchun 130024China

Four rare earth inorganic-organic hybrid compounds based on Keggin-type polyoxometalate {SiW_(12)}with general formula [{RE(DMF)_(4)(H_(2)O)_4RE(DMF)_(6)}_(2){SiW_(12)O_(40)}_(3)](RE = La(1),Pr(2),Sm(3),Eu(4),DMF=N,N-dimethylformamide) were synthesized by the conventional solution *** analyses indicate that four compounds are isostructural and are all built from three [SiW_(12)O_(40)]^(4-) polyoxoanions and DMF ligands linked by RE^(3+).Compounds 1-4 are extremely sensitive to UV light and present excellent photochromic properties,in which the coloring and fading time of samples are both no more than 2 min,and the reversible coloring-fading process can be repeated for at least 10 cycles with little fatigue,suggesting that compounds 1-4 can be a series of fast-responsive and durable photochromic ***,the solid-state photoluminescence spectra of compounds 3(Sm) and 4(Eu)display strong characteristic emissions of rare earth ions based on f-f ***,compound4(Eu) has a longer fluorescence lifetime up to 566.74 μ***,co mpounds 3(Sm) and 4(Eu) exhibit the switchable luminescence behavior induced by photochromism,which allows them to be used as potential molecular switches.

关键词： Inorganic-organic hybrid Keggin-type polyoxometalates Rare earths Photochromism Photoluminescence

Ability of Helicobacter pylori to internalize into Candida

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2024年第16期30卷 2281-2284页

作者： Zheng-hong Chen Jian-Chao Sun Ting-Xiu yang Gu-Zhen cui Key Laboratory of Microbiology and Parasitology of Education Department of Guizhou Guizhou Medical UniversityGuiyang 561113Guizhou ProvinceChina Key Laboratory of Endemic and Ethnic Diseases of Ministry of Education Guizhou Medical UniversityGuiyang 561113Guizhou ProvinceChina Joint Laboratory of Helicobacter Pylori and Intestinal Microecology Affiliated Hospital of Guizhou Medical UniversityGuiyang 550009Guizhou ProvinceChina Department of Quality Control Guizhou Provincial Center for Clinical LaboratoryGuiyang 550002Guizhou ProvinceChina Department of Hospital Infection and Management Guizhou Provincial People’s HospitalGuiyang 550002Guizhou ProvinceChina

The following are our views regarding the“letter to the editor”(Helicobacter is preserved in yeast vacuoles!Does Koch’s postulates confirm it?)by Alipour and Gaeini,and the response“letter to the editor”(Candida accommodates nonculturable Helicobacter pylori in its vacuole-Koch’s postulates aren’t applicable)by Siavoshi and *** and Gaeini rejected the methods,results,discussion,and conclusions summarized in a review article by Siavoshi and *** present article reviews and discusses evidence on the evolutionary adaptation of Helicobacter pylori(***)to thrive in Candida cell vacuoles and concludes that Candida could act as a Trojan horse,transporting potentially infectious *** into the stomach of humans.

关键词： Helicobacter pylori Candida yeast Intracellular presence Helicobacter pylori-specific gene Helicobacter pylori transmission

Mitochondrial-Oriented Injectable Hydrogel Microspheres Maintain Homeostasis of Chondrocyte Metabolism to Promote Subcellular Therapy in Osteoarthritis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research 2024年第3期7卷 775-790页

作者： Li Chen Jianye yang Zhengwei Cai Yanran Huang Pengcheng Xiao hong Chen Xiaoji Luo Wei Huang Wenguo cui Ning Hu Department of Orthopedics The First Affiliated Hospital of Chongqing Medical UniversityOrthopedic Laboratory of Chongqing Medical UniversityChongqing 400016China Department of Orthopaedics Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint DiseasesShanghai Institute of Traumatology and OrthopaedicsRuijin HospitalShanghai Jiao Tong University School of Medicine197 Ruijin 2nd RoadShanghai 200025China.

Subcellular mitochondria serve as sensors for energy metabolism and redox balance, and the dynamic regulation of functional and dysfunctional mitochondria plays a crucial role in determining cells' fate. Selective removal of dysfunctional mitochondria at the subcellular level can provide chondrocytes with energy to prevent degeneration, thereby treating osteoarthritis. Herein, to achieve an ideal subcellular therapy, cartilage affinity peptide (WYRGRL)-decorated liposomes loaded with mitophagy activator (urolithin A) were integrated into hyaluronic acid methacrylate hydrogel microspheres through microfluidic technology, named HM@WY-Lip/UA, that could efficiently target chondrocytes and selectively remove subcellular dysfunctional mitochondria. As a result, this system demonstrated an advantage in mitochondria function restoration, reactive oxygen species scavenging, cell survival rescue, and chondrocyte homeostasis maintenance through increasing mitophagy. In a rat post-traumatic osteoarthritis model, the intra-articular injection of HM@WY-Lip/UA ameliorated cartilage matrix degradation, osteophyte formation, and subchondral bone sclerosis at 8 weeks. Overall, this study indicated that HM@WY-Lip/UA provided a protective effect on cartilage degeneration in an efficacious and clinically relevant manner, and a mitochondrial-oriented strategy has great potential in the subcellular therapy of osteoarthritis.

关键词： spheres remove thereby

Potential application of radiant floor cooling systems for residential buildings in different climate zones

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Building Simulation 2024年第4期17卷 543-560页

作者： Mengying cui yang Song Yudong Mao Kaimin yang Jiying Liu Zhe Tian School of Thermal Engineering Shandong Jianzhu UniversityJinan250101China School of Environmental Science and Engineering Tianjin UniversityTianjin300072China Key Lab of Building Environment and Energy of Tianjin Tianjin UniversityTianjin300072China

A radiant floor cooling system(RFCS)is a high-comfort and low energy consumption system suitable for residential *** floor systems usually work with fresh air,and their operating performance is affected by climatic *** and outdoor environmental disturbances and the system’s control strategy affect the indoor thermal comfort and energy efficiency of the ***,a multi-story residential building model was established in this *** system simulation program was used to study the operation dynamics of three control strategies of the RFCS based on the calibrated ***,the performance of the control strategies in five climate zones in China were compared using multi-criteria decision-making in *** results show that control strategy has a negligible effect on condensation risk,but the thermal comfort and economic performance differ for different control *** adaptability of different control strategies varies in different climate zones based on the consideration of multiple *** performance of the direct-ground cooling source system is better in Hot summer and warm winter *** variable air volume control strategy scores higher in Serve cold and Temperate zones,and the hours exceeding thermal comfort account for less than 3%of the total simulation ***,it is suggested to choose the RFCS control strategy for residential buildings according to the climate zone characteristics,to increase the energy *** results provide a reliable reference for implementing RFCSs in residential buildings.

关键词： control strategy radiant floor cooling system residential building energy efficiency climate zones

A Special Editor’s Issue on Magnesium Matrix Composites

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Metallurgica Sinica(English Letters) 2024年第3期37卷 389-390页

作者： Xianhua Chen hong yang College of Materials Science and Engineering Chongqing UniversityChongqing 400045China National Engineering Research Center for Mg Alloys Chongqing UniversityChongqing 400045China

Magnesium(Mg)alloys offer distinct advantages as one of the lightest structural *** remarkable weight advantages,being 35%lighter than aluminum alloy and a striking 78%lighter than steel,make them a focal point for research in automotive and aerospace *** emphasis stems from the overarching goal of reducing energy costs and enhancing overall performance[1,2].

关键词： alloy steel alloys

Parametric“non-nested”discriminants for multiplicities of univariate polynomials

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Mathematics 2024年第8期67卷 1911-1932页

作者： Hoon hong Jing yang Department of Mathematics North Carolina State UniversityRaleighNC 27695USA SMS-HCIC-School of Mathematics and Physics Center for Applied Mathematics of GuangxiGuangxi Minzu UniversityNanning 530006China

We consider the problem of complex root classification,i.e.,finding the conditions on the coefficients of a univariate polynomial for all possible multiplicity structures on its complex *** is well known that such conditions can be written as conjunctions of several polynomial equalities and one inequality in the *** polynomials in the coefficients are called discriminants for *** is also known that discriminants can be obtained using repeated parametric greatest common *** resulting discriminants are usually nested determinants,i.e.,determinants of matrices whose entries are determinants,and so *** this paper,we give a new type of discriminant that is not based on repeated greatest common *** new discriminants are simpler in the sense that they are non-nested determinants and have smaller maximum degrees.

关键词： parametric polynomial complex roots discriminant multiplicity resultant

Interplay between magnetic gap and quasiparticle lifetime in topological insulator ferromagnet/f-wave superconductor junctions

在线全文

学校读者我要写书评

暂无评论

Communications in Theoretical Physics 2024年第7期76卷 156-164页

作者： hong Li Xinjian yang College of Science China University of PetroleumQingdao 266580China

Using the modified Blonder-Tinkham-Klapwijk(BTK)theory,the interplay between the lifetime of quasi particles and the magnetic gap in a topological insulator-based ferromagnet/fwave superconductor(TI-based FM/f-wave SC)tunnel structure is theoretically *** symmetries of f_(1) and f_(2) waves are considered for superconducting pairing *** results indicate that reducing the finite quasi-particle lifetime will induce a transformation of energy-gap peaks into a zero-bias peak in tunneling conductance spectrum,as well as a transformation of energy-gap dips into a zero-bias dip in shot noise spectrum,ultimately resulting in the smoothing of the zero-bias conductance peak and the zero-bias shot noise *** increase in magnetic gap will suppress the tunnel conductance and shot noise when the conventional Andreev retroreflection dominates,but will enhance them when the specular Andreev reflection is *** specular Andreev reflection and conventional Andreev retro-reflection will be enhanced as the quasi-particle lifetime *** Fermi energy equals the magnetic gap,shot noise and tunneling conductance vanish across all energy *** findings not only contribute to a better understanding of specular Andreev reflection in the FM/f-wave SC junction based on TIs but also provide insights for experimentally determining the f-wave pairing symmetry.

关键词： TI-based FM/f-wave SC junction magnetic gap finite-quasi-particles lifetime Andreev retro-reflection specular Andreev reflection

Spatial distribution of shallow landslides caused by Typhoon Lekima in 2019 in Zhejiang Province, China

在线全文

学校读者我要写书评

暂无评论

Journal of Mountain Science 2024年第5期21卷 1564-1580页

作者： cui Yulong yang Liu XU Chong ZHENG Jun School of Civil Engineering and Architecture Anhui University of Science and TechnologyHuainan 232001China National Institute of Natural Hazards Ministry of Emergency Management of ChinaBeijing 100085China Department of Civil Engineering Zhejiang UniversityHangzhou 310058China

In recent years, the coastal region of Southeast China has witnessed a significant increase in the frequency and intensity of extreme rainfall events associated with landfalling typhoons. The hilly and mountainous terrain of this area, combined with rapid rainfall accumulation, has led to a surge in flash floods and severe geological hazards. On August 10, 2019, Typhoon Lekima made landfall in Zhejiang Province, China, and its torrential rainfall triggered extensive landslides, resulting in substantial damage and economic losses. Utilizing high-resolution satellite images, we compiled a landslide inventory of the affected area, which comprises a total of 2,774 rainfallinduced landslides over an area of 2965 km2. The majority of these landslides were small to mediumsized and exhibited elongated, clustered patterns. Some landslides displayed characteristics of high-level initiation, obstructing or partially blocking rivers, leading to the formation of debris dams. We used the inventory to analyze the distribution pattern of the landslides and their relationship with topographical, geological, and hydrological factors. The results showed that landslide abundance was closely related to elevation, slope angle, faults, and road density. The landslides were predominantly located in hilly and low mountainous areas, with elevations ranging from 150 to 300 m, slopes of 20 to 30 degrees, and a NE-SE aspect. Notably, we observed the highest Landslide Number Density(LND) and Landslide Area Percentage(LAP) in the rhyolite region. Landslides were concentrated within approximately 4 km on either side of fault zones, with their size and frequency negatively correlated with distances to faults, roads, and river systems. Furthermore, under the influence of typhoons, regions with denser vegetation cover exhibited higher landslide density, reaching maximum values in shrubland areas. In areas experiencing significantly increased concentrated rainfall, landslide density also showed a corr

关键词： Typhoon rainfall Landslide characteristics Spatial distribution Southeast coastal region