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Pulsed Microfluid Force-Based On-Chip Modular Fabrication for Liver Lobule-Like 3D Cellular Models

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Cyborg and Bionic Systems 2021年第1期2021卷 222-233页

作者： J.cui H.P.Wang Q.Shi T.Sun Science and Technology on Electronic Test and Measurement Laboratory North University of ChinaTaiyuan 030051China Intelligent Robotics Institute School of Mechatronical EngineeringBeijing Institute of TechnologyBeijing 100081China Beijing Advanced Innovation Center for Intelligent Robots and Systems Beijing Institute of TechnologyBeijing 100081China Key Laboratory of Biomimetic Robots and Systems(Beijing Institute of Technology) Ministry of EducationBeijing 100081China

In vitro three-dimensional(3D)cellular models with native tissue-like architectures and functions have potential as alternatives to human tissues in regenerative medicine and drug ***,it is difficult to replicate liver constructs that mimic in vivo microenvironments using current approaches in tissue engineering because of the vessel-embedded 3D structure and complex cell distribution of the *** paper reports a pulsed microflow-based on-chip 3D assembly method to construct 3D liver lobule-like models that replicate the spatial structure and functions of the liver *** heterogeneous cell-laden assembly units with hierarchical cell distribution are fabricated through multistep photopatterning of different cell-laden *** fluid force interaction by pulsed microflow,the hierarchical assembly units are driven to a stack,layer by layer,and thus spatially assemble into 3D cellular models in the closed liquid chamber of the assembly *** 3D models with liver lobule-like hexagonal morphology and radial cell distribution allow the dynamic perfusion culture to maintain high cell viability and functional expression during long-term culture in *** results demonstrate that the fabricated 3D liver lobule-like models are promising for drug testing and the study of individual diagnoses and treatments.

关键词： culture maintain spatially

Microwave metamaterials: from exotic physics to novel information systems

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Frontiers of Information Technology & Electronic Engineering 2020年第1期21卷 4-26页

作者： Rui-yuan WU Tie-jun cui State Key Laboratory of Millimeter Waves Southeast UniversityNanjing 210096China Synergetic Innovation Center of Wireless Communication Technology Southeast UniversityNanjing 210096China

Metamaterials and metasurfaces have attracted much attention due to their powerful ability to control electromagnetic(EM)*** this paper,we review the recent developments in the field of EM metamaterials,starting from their exotic physics to their applications in novel information ***,we show the fundamental understanding on traditional metamaterials based on the effective medium theory and related applications,such as invisibility cloaks and ***,we review the two-dimensional versions of metamaterials,i.e.,metasurfaces,for controlling spatial waves and surface waves and thereafter present their typical *** particular,we briefly introduce spoof surface plasmon polaritons and their applications in microwave *** the above approach,we emphatically present the concepts of digital coding metamaterials,programmable metamaterials,and information *** extending the principles of information science to metamaterial designs,several functional devices and information systems are presented,which enable digital and EM-wave manipulations ***,we give a brief summary of the development prospects for microwave metamaterials.

关键词： Metamaterial Effective medium theory Metasurface Surface plasmon polaritons Digital coding Programmable Information

The Observation of Small Polaron Tunnelling in the ab-Plane of K_(0.85)Fe_(1.66)Se_(2.0)

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Chinese Physics Letters 2013年第10期30卷 171-174页

作者： MA Yong-Chang YAN Qian ZHAO Jie LU cui-Min School of Materials Science and Engineering Tianjin University of TechnologyTianjin 300384 Tianjin Key Lab for Photoelectric Materials and Devices Tianjin 300384 Key Laboratory of Display Materials and Photoelectric Devices(Ministry of Education) Tianjin University of TechnologyTianjin 300384

The temperature-dependent conductivity spectrum from 3×10^(2) Hz to 1×10^(8) Hz in the ab-plane of a K0.85Fe1.66Se2.0 single crystal is *** dc measurements indicate that the charge transport can be described well by the variable range hopping *** the ac conductivity spectrum,clear evidence for small polaron tunnelling with an activation energy of about 155 meV in ab-plane is *** decreasing temperature,the real part of the dielectric spectrum shifts towards lower frequencies and also shows a wider distribution of the relaxation *** 140 K,the peak position of the dielectric loss spectra begins to deviate from thermal excitation behavior,reflecting the freezing of the phonon which assists the tunnelling.

关键词： spectrum dielectric conductivity

MDSSD:multi-scale deconvolutional single shot detector for small objects

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Science China(Information Sciences) 2020年第2期63卷 98-100页

作者： Lisha cui Rui MA Pei LV Xiaoheng JIANG Zhimin GAO Bing ZHOU Mingliang XU Center for Interdisciplinary Information Science Research Zhengzhou University

Dear editor,Object detection has always been the focus and challenge in the field of computer vision, especially the small object detection. With the arrival of deep convolutional networks (Conv Nets [1]), the perform... 详细信息

关键词： MDSSD:multi-scale deconvolutional single shot detector for small objects SSD

Water and fluorinated alcohol mediated/promoted tandem insertion/aerobic oxidation/bisindolylation under metal-free conditions:Easy access to bis(indolyl)methanes

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Chinese Chemical Letters 2021年第5期32卷 1696-1700页

作者： Yong Wang Xinyi Cao Jingfei Ji Xiuling cui Chao Pi Leyao Zhao Yangjie Wu Henan Key Laboratory of Chemical Biology and Organic Chemistry Key Laboratory of Applied Chemistry of Henan UniversitiesGreen Catalysis Centerand College of ChemistryZhengzhou UniversityZhengzhou 450052China International College Zhengzhou UniversityZhengzhou 450052China

A green tandem reaction,including insertion/aerobic oxidation/bisindolylation,starting from indoles and diazo compounds has been *** combination of water and fluorinated alcohol plays dual roles as solvent and promoter in this chemical *** oxygen in the air acts as an oxidant.3,3’-Bis(indolyl)methanes with quaternary carbon were produced under metal-free *** any catalyst and additive were required.N2 and water were released as sole *** of water and fluorinated alcohol resulted in Wolff rearrangement product.

关键词： Bis(indolyl)mcthanes Diazo Fluorinated alcohol Indole Water

少数民族农民工城市融入水平及影响因素的定量研究——基于2017年全国流动人口动态监测调查数据

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西南民族大学学报（人文社会科学版） 2021年第11期42卷 1-9页

作者：杨风陶斯文济南大学政法学院山东济南250022 西南民族大学中华民族共同体研究院四川成都610041

文章尝试构建农民工城市融入水平指标体系,利用2017年全国流动人口动态监测调查数据,运用均值分解和分位数分解方法,对少数民族农民工城市融入水平及其影响因素进行定量研究。研究发现:尽管少数民族农民工与汉族农民工城市融入指数均值... 详细信息

文章尝试构建农民工城市融入水平指标体系,利用2017年全国流动人口动态监测调查数据,运用均值分解和分位数分解方法,对少数民族农民工城市融入水平及其影响因素进行定量研究。研究发现:尽管少数民族农民工与汉族农民工城市融入指数均值差异较小,可是随着分位数的增加,两者之间的差距不断扩大;禀赋(特征)差异是两者均值差异的主因,禀赋(特征)对差异的影响随着分位数的增加先升后降(呈倒"U"型);少数民族农民工城市融入水平与受教育程度、婚姻状况正相关,与流动范围负相关,与现住房性质的关系呈"U"型;年龄、本次流动时间、开始此项工作时间的影响各有不同。为实现"让少数民族群众更好融入城市",需要提高少数民族农民工教育水平和劳动技能,妥善解决农民工城市居住问题,引导中西部地区少数民族农民工就近城镇化,完善少数民族流动人口服务管理体系。

关键词：少数民族农民工城市融入影响因素 Oaxaca-Blinder分解

A mouse model of vitiligo based on endogenous auto-reactive CD8+T cell targeting skin melanocyte

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Cell Regeneration 2022年第1期11卷 316-332页

作者： Daoming Chen Zijian Xu Jun cui Ting Chen National Institute of Biological Sciences BeijingChina Tsinghua Institute of Multidisciplinary Biomedical Research Tsinghua UniversityBeijingChina

Vitiligo is the most common human skin depigmenting *** is mediated by endogenous autoreactive CD8+T cells that destruct skin *** disease has an estimated prevalence of 1%of the global population and cur-rently has no *** models are indispensable tools for understanding vitiligo pathogenesis and for developing new ***,we describe a vitiligo mouse model which recapitulates key clinical features of vitiligo,including epidermis depigmentation,CD8+T cell infiltration in skin,and melanocyte *** activate endogenous autoreactive cytotoxic CD8+T cells targeting melanocytes,this model relies on transient inoculation of B16F10 melanoma cells and depletion of CD4+regulatory T *** cellular level,epidermal CD8+T cell infiltration and melanocyte loss start as early as Day 19 after *** apparent epidermis depigmentation occurs 2 months *** protocol can efficiently induce vitiligo in any C57BL/6 background mouse strain,using only commercially available *** enables researchers to carry out in-depth in vivo vitiligo studies utilizing mouse genetics tools,and provides a powerful platform for drug discovery.

关键词： Vitiligo Mouse model Activation Endogenous autoreactive cytotoxic CD8+T cells

An Improved Random Walker using Spatial Feature for Image Segmentation

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An Improved Random Walker using Spatial Feature for Image Se...

Characterization of mechanical properties of aluminum cast alloy at elevated temperature

第25届中国控制与决策会议

作者： Zhaohua cui Wenna Li Gai Pan Liqun Gao School of information science and engineering Northeastern University Unit 65041

ISBN: (纸本)9781467355339

The random walker algorithm for image segmentation is an effective method. However, the traditional random walker algorithm （RW） is only determined by the adjacent node （pixels） intensity information in the feature space, and the algorithm does not take the spatial feature information of nodes （pixels） into consideration, which makes the segmentation results discrete in the spatial distribution. In this work, an improved random walker algorithm （SRW） has been proposed to improve the efficiency and accuracy of the extraction with complicate background. Firstly, spatial feature information has been employed to combine with the intensity information to measure weights between adjacent nodes （pixels）. The freedom parameters have been then adjusted for the two features above to obtain the scale. Finally, the experimental result shows that the improved random walker algorithm （SRW） is effective in extracting objects contour with complicate background.

关键词： Image Segmentation Random Walker Algorithm Spatial Feature

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Applied Mathematics and Mechanics(English Edition) 2018年第7期39卷 967-980页

作者： Shuiqiang ZHANG Yichi ZHANG Ming CHEN Yanjun WANG Quan cui Rong WU D.AROLA Dongsheng ZHANG Shanghai Institute of Applied Mathematics and Mechanics Shanghai University Shanghai Key Laboratory of Mechanics in Energy Engineering Shanghai University University of Michigan-Shanghai Jiao Tong University Joint Institute Shanghai Jiao Tong University Motor Technical Center Shanghai Automotive Industry Corporation Department of Materials Science and Engineering University of Washington Department of Mechanics College of Sciences Shanghai University

The tensile response, the low cycle fatigue （LCF） resistance, and the creep behavior of an aluminum （A1） cast alloy are studied at ambient and elevated temperatures. A non-contact real-time optical extensometer based on the digital image correlation （DIC） is developed to achieve strain measurements without damage to the specimen. The optical extensometer is validated and used to monitor dynamic strains during the mechanical experiments. Results show that Young＇s modulus of the cast alloy decreases with the increasing temperature, and the percentage elongation to fracture at 100 ℃ is the lowest over the temperature range evaluated from 25 ℃ to 300 ℃. In the LCF test, the fatigue strength coefficient decreases, whereas the fatigue strength exponent increases with the rising temperature. The fatigue ductility at 100 ℃. As expected, the resistance to and changes from 200 ℃ to 300 ℃. coefficient and exponent reach maximum values creep decreases with the increasing temperature

关键词： mechanical behavior aluminum(A1)cast alloy elevated temperature digital image correlation(DIC) optical extensometer