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Potential of Bamboo Species Guadua trinii and Guadua angustifolia for nanocellulose Production

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Journal of Renewable Materials 2024年第9期12卷 1541-1555页

作者： Agatha E.R.Prado Gárate fernando E.felissia María cristina Area Teresa Suirezs María Evangelina Vallejos Círculo de Investigación del Bambú Universidad Nacional Agraria La Molina(UNALM)Lima15026Perú Instituto de Materiales de Misiones(IMAM) Universidad Nacional de Misiones(UNaM)Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET)Facultad de Ciencias ExactasQuímicas y Naturales(FCEQYN)Programa de Celulosa y Papel(PROCyP)Posadas3300Argentina Instituto de Materiales de Misiones(IMAM) Universidad Nacional de Misiones(UNaM)Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET)Facultad de Ciencias Forestales(FCF)Eldorado3380Argentina

non-traditional lignocellulosic materials are a significant resource for producing high-value products,including *** work studied the nanocellulose obtention from chemical pulps of the two fast-growing bamboo species,Guadua trinii,and Guadua *** pulps were produced by soda-anthraquinone(S)pulping from both autohydrolysis-pretreated(H)and unpretreated bamboo ***-pretreated(SHP)and unpretreated soda-anthraquinone(AQ)(SP)pulps were characterized by yield,Kappa number,alpha,beta,and gamma cellulose,degree of polymerization,water retention value,and *** nanocellulose was produced by a sequential chemical oxidation treatment(2,2,6,6-tetramethylpiperidine-1-oxyl,TEMPO reagent)and mechanical *** was characterized by carboxylic group content and *** results revealed that autohydrolysis pretreatment resulted in a higher hemicelluloses extraction in *** contrast,the pulping yield of unpretreated samples was higher for ***,and the soda-AQ pulps from this species exhibited better delignification than the autohydrolysis-pretreated *** crystallinity index values of the obtained pulps were high(>80%),and the alpha-cellulose contents were *** viscosities of the aqueous nanocellulose suspensions were higher for the nanocellulose solutions obtained from the unpretreated soda-AQ ***,nanocellulose from *** unpretreated soda-AQ pulps had a higher rate of carboxylic *** results of this work are significant in assessing the potential of both bamboo species as a source of high-value products within the biorefinery framework because the viscosities of the aqueous nanocellulose suspensions depend on the size and shape of *** has significant importance for industrial unit operations and potential applications.

关键词： natural fiber Guadua angustifolia Guadua trinii soda-anthraquinone pulp nanocellulose

MicroRnAs in inflammatory bowel disease:What do we know and what can we expect?

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World Journal of Gastroenterology 2024年第16期30卷 2184-2190页

作者： Ellen cristina Souza de Oliveira Ana Elisa Valencise Quaglio Thais Gagno Grillo Luiz Claudio Di Stasi Ligia Yukie Sassaki Department of Internal Medicine Medical SchoolSão Paulo State University(Unesp)Botucatu 18618-686São PauloBrazil Verum Ingredients Botucatu Technology ParkBotucatu 18605-525São PauloBrazil Department of Biophysics and Pharmacology Institute of BiosciencesSão Paulo State University(Unesp)Botucatu 18618-689São PauloBrazil

MicroRnAs(miRnAs),small non-coding RnAs composed of 18–24 nucleotides,are potent regulators of gene expression,contributing to the regulation of more than 30%of protein-coding *** that miRnAs are regulators of inflammatory pathways and the differentiation of intestinal epithelial cells,there is an interest in exploring their importance in inflammatory bowel disease(IBD).IBD is a chronic and multifactorial disease of the gastrointestinal tract;the main forms are Crohn's disease and ulcerative *** studies have investigated the dysregulated expression of miRnAs in IBD,demonstrating their important roles as regulators and potential biomarkers of this *** editorial presents what is known and what is expected regarding miRnAs in *** the important regulatory roles of miRnAs in IBD are clearly established,biomarkers for IBD that can be applied in clinical practice are lacking,emphasizing the importance of further *** regarding the influence of miRnAs on the inflammatory process and the exploration of their role in gene regulation are expected to provide a basis for the use of miRnAs not only as potent biomarkers in IBD but also as therapeutic targets for the control of inflammatory processes in personalized medicine.

关键词： MicroRnAs Inflammatory bowel disease Crohn’s disease Ulcerative colitis Biomarker Therapy

Extreme drought triggers parallel shifts in wood anatomical and physiological traits in upper treeline of the Mediterranean Andes

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Ecological Processes 2024年第01期13卷 132-143页

作者： Luiz Santini Jr. Dylan Craven Daigard Ricardo Ortega Rodriguez Manolo Trindade Quintilhan Stephanie Gibson-Carpintero cristina Aravena Torres fidel A.Roig Ariel A.Mu?oz Alejandro Venegas-Gonzalez Hémera Centro de Observación de la Tierra Universidad Mayor GEMA Center for Genomics Ecology and Environment Universidad Mayor Data Observatory foundation ANID Technology Center Depart-ment of forest Sciences ESALQ-University of Sao Paulo Department of Plant Biology Institute of Biology University of Campinas Instituto de Geografía Universidad Nacional Autónoma de México (UNAM) Argentine Institute of nivology Glaciology and Environmental Sciences(IANIGLA CONICET ) Institute of Geography Pontificia Universidad Católica de Valparaíso Instituto de Ciencias Agroalimentarias Animales y Ambientales (ICA3) Universidad de O'Higgins

Background Treeline ecotones of Mediterranean ecoregions have been affected by the increasing intensity and severity of droughts. Even though the effect of droughts on forest dynamics has been widely documented, knowledge is relatively scarce of how extreme climate episodes affect the hydraulic structure and, therefore, the phys-iology of woody plants. The Mediterranean Andes have experienced an uninterrupted period of drought since 2010, including an extremely dry year in 2019 with approximately 80% rainfall deficit. Here, we investigated shifts in wood anatomical and physiological traits of Kageneckia angustifolia, an endemic treeline species, in response to this drought *** We evaluated the xylem plasticity of three K. angustifolia populations across their natural distribution(31–35° SL) based on anatomical(vessel structure and distribution) and physiological(intrinsic water-use efficiency) variables in the tree rings. We focused on the period 2000–2020 that corresponds to before the megadrought(2000–2007),(ii) megadrought(2008–2018) and(iii) hyperdrought(2019–2020). The variables were annualized and analyzed by linear mixed-effects *** Our results provide insights to the anatomical and physiological mechanisms underlying the resilience of treeline forests to persistent droughts in central Chile. We found that the extreme drought in 2019–2020 triggered shifts in vessel size and frequency that increased hydraulic safety. These significant shifts in vessel traits occurred in parallel with a decrease in pit aperture area and an increase in water-use efficiency, further increasing the resilience of K. angustifolia to extreme drought *** Our results revealed coordinated shifts in vessel size and frequency and water-use efficiency in response to the megadrought, thereby reducing vulnerability to hydraulic failure. The apparent resilience of K. angustifolia to extreme droughts suggests that this adaptation to drought stress may incre

关键词： Dendro-anatomy Kageneckia angustifolia Xylem vulnerability Drought Climate change

Boll weevils in dry bolls:is there a performance disadvantage?

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Journal of Cotton Research 2024年第3期7卷 243-252页

作者： COELHO Beatriz S. LEITE Suzany A. SAnTOS Mateus P.dos MATES Eloito C.de MORAES Beatriz M.L.de BASTOS cristina S. GUEDES Raul n.C. MOREIRA Aldenise A. CASTELLAnI Maria A. Departamento de fitotecnia e Zootecnia Universidade Estadual do Sudoeste da BahiaVitória da ConquistaBA 45031‑900Brazil faculdade de Agronomia e Veterinária Universidade de BrasíliaBrasíliaDF 70910‑900Brazil Departamento de Entomologia Universidade Federal de ViçosaViçosaMG 36570‑900Brazil Pós‑GraduaCão em Agronomia(fitotecnia) Universidade Estadual do Sudoeste da BahiaVitória da ConquistaBA 45031‑900Brazil

Background Anthonomus grandis grandis is the main cotton pest in the Americas,with the potential to become a pest in other *** insect uses the plant's reproductive organs for feeding,oviposition,and survival strategies in the off-season,sheltering in dry *** study aimed to know the reproductive potential,feeding,longevity,and morphometric characteristics of boll weevils from dry bolls,squares,and *** were obtained from infested squares,dry bolls,and traps installed in cotton fields and the Caatinga *** weevil pairs were maintained in the laboratory to assess the oviposition,feeding holes,longevity,and morphometric measurements of the parental and f_(1) *** In the parental generation,boll weevils from traps(the Caatinga area and cotton cultivation)showed greater reproductive *** weevils from squares and the Caatinga area showed greater feeding activity compared with those from cotton *** rostrum length,thorax+abdomen length,and abdomen width were observed in boll weevils from cotton cultivation and dry *** origin of boll weevils parental generation did not affect progeny emergence *** f_(1) generation of boll weevils showed significant differences in average longevity depending on the origin of different ***,differences in rostrum lengths were observed,with the boll weevils coming from traps installed in cotton cultivation,the Caatinga area,and dry bolls being the *** thorax+abdomen length and abdomen width,the highest values were observed in those from the Caatinga area and cotton *** It was proven that dry bolls did not affect the reproductive,feeding,and longevity performance of boll weevils,enabling better insect fitness(reproduction and size)in relation to those coming from *** use of dry bolls as off-season shelter is an important survival strategy for the boll weevil.

关键词： Anthonomus grandis grandis Gossypium hirsutum Off-season Survival

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Effect of resistance training volume on body adiposity,metabolic risk,and inflammation in postmenopausal and older females:Systematic review and meta-analysis of randomized controlled trials

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Journal of Sport and Health Science 2024年第2期13卷 145-159页

作者： Paulo Ricardo Prado nunes Pamela Castro-e-Souza Anselmo Alves de Oliveira Bruno de freitas Camilo Gislaine cristina-Souza Lucio Marques Vieira-Souza Marcelo Augusto da Silva Carneiro Department of Body and Human Movement Minas Gerais State University(UEMG)37902-092 PassosMGBrazil University Center of Planalto de Araxa(UnIARAXA) 38180-129 AraxaMGBrazil Physical Activity Health and Ageing Research Group(GPASE)Minas Gerais State University(UEMG)37902-092 PassosMGBrazil Exercise and nutrition Research Group(GPEn) Minas Gerais State University(UEMG)37902-092 PassosMGBrazil Sport Sciences and Physical Exercise Study and Research Group(GEPCEEX) Minas Gerais State University(UEMG)37902-092 PassosMGBrazil Metabolism Nutrition and Exercise LaboratoryPhysical Education and Sport CenterLondrina State University(UEL)86050-070 LondrinaPRBrazil Postgraduate Program in Physical Education Federal University of Sergipe(UFS)49107-230 Sao CristovaoSEBrazil

Purpose:This meta-analytical study aimed to explore the effects of resistance training(RT) volume on body adiposity,metabolic risk,and inflammation in postmenopausal and older ***:A systematic search was performed for randomized controlled trials in PubMed,Scopus,Web of Science,and *** controlled trials with postmenopausal and older females that compared RT effects on body adiposity,metabolic risk,and inflammation with a control group(CG) were *** reviewers selected the studies,extracted the data,and performed the risk of bias and certainty of the evidence(Grading of Recommendations,Assessment,Development,and Evaluation(GRADE)) *** body and abdominal adiposity,blood lipids,glucose,and C-reactive protein were included for meta-analysis.A random-effects model,standardized mean difference(Hedges’ g),and 95% confidence interval(95%CI) were used for ***:Twenty randomized controlled trials(overall risk of bias:some concerns;GRADE:low to very low) with overweight/obese postmenopausal and older females were *** groups were divided into low-volume RT(LVRT,~44 sets/week) and high-volume RT(HVRT,~77 sets/week).Both RT groups presented improved body adiposity,metabolic risk,and inflammation when compared to ***,HVRT demonstrated higher effect sizes than LVRT for glucose(HVRT=-1.19;95%CI:-1.63 to-0.74;LVRT=-0.78;95%CI:-1.15 to-0.41) and C-reactive protein(HVRT=-1.00;95%CI:-1.32 to-0.67;LVRT=-0.34;95%CI,-0.63 to-0.04)) when compared to ***:Compared to CG,HVRT protocols elicit greater improvements in metabolic risk and inflammation outcomes than LVRT in overweight/obese postmenopausal and older females.

关键词： C-reactive protein fat mass Lipid profile Menopause Strength training

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Microplastics Detection and Identification in the Waters along Coastal Areas of Borongan City

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Open Journal of Ecology 2024年第9期14卷 663-672页

作者： Aljon Victor G. nibalvos cristina T. nibalvos College of Science Eastern Samar State University Borongan City Philippines College of nursing and Allied Sciences Eastern Samar State University Borongan City Philippines

This study detects the presence of microplastics in the coastal areas of Borongan City, Eastern Samar, this specifically implies the microplastics present in the waters along coastal areas of Borongan City. Two (2) sampling areas were identified and selected for the presence of these microcontaminants using density separation, filtration and microscopic identification. Results reveal a total of 35 microplastics observed from the water samples collected, with this the microplastics from Baybay boulevard with an average of 0.79 microplastics per Liter, while the average microplastic contamination in Hilangagan beach resort was calculated at 0.43 microplastics per Liter. This sums up to an average of 0.49 microplastics per Liter for both sampling sites in Borongan City.

关键词： Microplastics Microcontaminants Borongan City Density Separation Microscopic Identification nonbiodegradable Contaminants

Artemisia vulgaris Induces Tumor-Selective ferroptosis and necroptosis via Lysosomal Ca^(2+) Signaling

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Chinese Journal of Integrative Medicine 2024年第6期30卷 525-533页

作者： Lucas dos Santos Zamarioli Michele Rosana Maia Santos Adolfo Garcia Erustes Vanessa Marques Meccatti Thais Cristine Pereira Soraya S Smaili Maria cristina Marcucci Carlos Rocha Oliveira Gustavo JS Pereira Claudia Bincoletto Department of Pharmacology Paulista School of MedicineFederal University of São PauloSão PauloSP04044-020Brazil Research Group on Phytocomplexes and Cell Signaling School of Health SciencesAnhembi Morumbi UniversitySão PauloSP03164-000Brazil Department of Biosciences and Oral Diagnosis Institute of Science and TechnologySão Paulo State University(ICT-UNESP)São PauloSP12231-280Brazil

Objective To evaluate the chemical composition and effects of Artemisia vulgaris(AV)hydroalcoholic extract(HEAV)on breast cancer cells(MCf-7 and SKBR-3),chronic myeloid leukemia(K562)and nIH/3T3 *** Phytochemical analysis of HEAV was done by high-performance liquid chromatography-mass(HPLC)*** and cell death studies were performed using trypan blue and Annexin/fITC-7AAD,***-1(fer-1)and necrostatin-1(nec-1)were used to assess the mode of HEAV-induced cell death and acetoxymethylester(BAPTA-AM)was used to verify the involvement of cytosolic calcium in this *** calcium measurements were made using *** HEAV decreased the viability of MCf-7,SKBR-3 and K562 cells(Pf HEAV-treated K562 cells was reduced compared to HEAV-exposed fibroblasts(Pnt of K562 cells with HEAV induced cell death primarily by late apoptosis and necrosis in assays using annexin V-fITC/7-AAD(Pf nec-1 and fer-1 increased the viability of K562 cells treated with HEAV relative to cells exposed to HEAV alone(Pnduced Ca^(2+)release mainly from lysosomes in K562 cells(Pfurthermore,BAPTA-AM,an intracellular Ca^(2+)chelator,decreased the number of non-viable cells treated with HEAV(Pnclusions HEAV is cytotoxic and activates several modalities of cell death,which are partially dependent on lysosomal release of Ca^(2+).These effects may be related to artemisinin and caffeoylquinic acids,the main compounds identified in HEAV.

关键词： Artemisia vulgaris necroptosis ferroptosis late apoptosis Ca^(2+)signaling

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How secure can we expect the surveillance policies to be after the implementation in T1 polyps with carcinoma?

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World Journal of Gastrointestinal Endoscopy 2024年第9期16卷 502-508页

作者： cristina Mateos Sanchez Elvira Quintanilla Lazaro Luis Ramon Rabago Department of Gastroenterological Severo Ochoa HospitalMadridLeganes 28911Spain Department of Gastroenterology San Rafael HospitalMadrid 28016Spain

Approximately 7%of the polyps resected endoscopically have an adenocarcinoma focus,with no previous endoscopic evidence of *** raises the question of whether endoscopic resection has been ***,there is no consensus on what the endoscopic and histological criteria for good prognosis are,the appropriate follow-up strategy and what are the long-term *** aim of the retrospective study by fábián et al was to evaluate the occurrence of local relapse or distant metastasis in those tumors that were resected endoscopically compared to those that underwent oncologic *** concluded that,regardless of the treatment strategy chosen,there was a higher recurrence rate than described in the literature and that adherence to follow-up was *** management approach for an endoscopically benign polyp histologically confirmed as adenocarcinoma depends on the presence of any of the previously described poor prognostic histological *** none of these factors are present and the polyp has been completely resected en bloc(R0),active surveillance is considered appropriate as endoscopic resection is deemed *** results highlight,once again,the need for further multicentric clinical practice studies to obtain more evidence for the purpose of establishing appropriate treatment and follow-up strategies.

关键词： pT1 adenocarcinoma polyps pT1 follow up management Histological recurrence rate of pT1 adenocarcinoma Endoscopic and histologic poor prognostic criteria

Characterization of the molecular dysfunctions occurring in Aicardi-Goutieres syndrome patients with mutations in ADAR1

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Genes & Diseases 2024年第3期11卷 116-119页

作者： Sofan Al wardat Loredana frasinlli Elisa Orecchini federica Rey Silvia Anna Ciafre Silvia Galardi Jessica Garau Stella Gagliardi Simona Orcesi Davide Tonduti Stephana Carelli cristina Cereda Ernesto Picardi Alessandro Michienzi Department of Biomedicine and Prevention University of Rome Tor VergataRome 00133Italy Pediatric Clinical Research Center"Romeo ed Enrica Invernizzi" Department of Biomedical and Clinical SciencesUniversity of MilanoMilano 20157Italy Center of functional Genomics and Rare Diseases Department of PediatricsBuzzi Children's HospitalMilano20154Italy Department of Child neurology and Psychiatry IRccs Mondino FoundationPavia 27100Italy Unit of Pediatric neurology C.O.A.L.A(Center for Diagnosis and Treatment of Leukodystrophies)Buzzi Children's HospitalMilano 20154Italy Department of Biosciences Biotechnologies and EnvironmentUniversityof Bari"AldoMoro"Bari 70125Italy Institute of Biomembranes Bioenergetics and Molecular Biotechnologies(IBIOM)National Research Council(CNR)Bari 70126Italy Biostructures and Biosystems national Institute(InBB) Rome00136Italy Institute of Biochemistry and Cell Biology IBBC-CNRCampus Adriano Buzzati TraversoRome 00015Italy

Aicardi-Goutieres syndrome(AGS)is a systemic inflammatory disorder caused by mutations in any one of the nine different genes,whose deficiency provokes a type I(interferon)Ifn response probably central to pathogenesis.^(1) ADAR1,one of the genes mutated in AGS(AGS6),encodes for an enzyme that belongs to the ADAR family(ADAR1,ADAR2,and ADAR3)that catalyzes the conversion of adenosine to inosine within double-stranded RnAs(dsRnAs)(RnA editing A-to-1).

关键词： ADAR1 interferon res