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Nature Conservation and Biodiversity Monitoring through a Spatial Data Infrastructure

Journal of Geodesy and Geomatics Engineering 2014年第1期1卷 1-10页

作者： cristina oana cristian vasile simona ipate (Staiculeseu) Esri Romania Bucharest 011774 Romania

One of the main concerns of the European Union environment policy is the deterioration of natural habitats and the threats posed to certain species under the Habitat Directive. With its huge diversity of plant and animal species and high level of endemism, Romania is nominated as a European biodiversity hotspot. Biodiversity is being lost at a dramatic rate unless strategically conservation measurements are taken. Halting the loss of biodiversity is regarded as a priority to the European Member States which are encouraged to work together within the same strong legislative framework in order to protect our most vulnerable species and habitat types. Romania is also in the process of developing the Spatial Data Infrastructure in response to Geographic Information 2000 Initiative launched by the European Commission in 1996 and the INSPIRE （Infrastructure for Spatial Information in Europe） initiative launched in 2001. The focus of this article is the development of the geospatial architecture framework and applications required for efficient inventory and mapping of natural habitats and wild species of community interest. Implementing a biodiversity geoportal application is seen as critical in order to help users share the geospatial information in the environment and sustainable development sectors.

关键词： Geoportals biodiversity INSPIRE metadata standards.

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Contribution of the IL-17/IL-23 axis to the pathogenesis of inflammatory bowel disease

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World Journal of Gastroenterology 2015年第19期21卷 5823-5830页

作者： cristina-Sorina Cǎanǎ Ioana Berindan Neagoe vasile Cozma cristian Magdas Flaviu Tǎbǎan Dan Lucian Dumitrasu Department of Medical Biochemistry "Iuliu Hateganu"University of Medicine and Pharmacy Department of Immunology "Iuliu Hateganu"University of Medicine and Pharmacy Department of Parasitology and Parasitic Diseases University of Agricultural Sciences and Veterinary Medicine Department of Morphopathology University of Agricultural Sciences and Veterinary Medicine 2~(nd) Medical Department "Iuliu Hateganu"University of Medicine and Pharmacy

Inflammatory bowel diseases(IBDs) are chronic disorders of modern society, requiring management strategies aimed at prolonging an active life and establishing the exact etiology and *** idiopathic diseases have environmental, genetic,immunologic, inflammatory, and oxidative stress components. On the one hand, recent advances have shown that abnormal immune reactions against the microorganisms of the intestinal flora are responsible for the inflammation in genetically susceptible individuals. On the other hand, in addition to T helper cell-type(Th) 1 and Th2 immune responses,other subsets of T cells, namely regulatory T cells and Th17 maintained by IL-23 are likely to develop IBD. IL-23 acts on innate immune system members and also facilitates the expansion and maintenance of Th17 cells. The IL-17/IL-23 axis is relevant in IBD pathogenesis both in human and experimental studies. Novel biomarkers of IBD could be calprotectin,microRNAs, and serum proinflammatory *** efficient strategy for IBD therapy is represented by the combination of IL-17 A and IL-17 F in acute IL-17 A knockout TNBS-induced colitis, and also definite decrease of the inflammatory process in IL-17 F knockout, DSS-induced colitis have been *** the correlation between innate and adaptive immune systems, we hope to obtain a focused reviewin order to facilitate future approaches aimed at elucidating the immunological mechanisms that control gut inflammation.

关键词： Crohn's disease Inflammatory boweldisease Cytokines Ulcerative colitis

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