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A single session of strength training changed plasma levels of resistin,but not leptin in overweight and obese men

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Sports Medicine and Health Science 2024年第4期6卷 324-330页

作者： Yago Martins Fortes Antonio Felipe Souza-Gomes Alessandro Roberto Silveira Moreira Leo Nogueira Campos Samara Silva de Moura Lucelia Scarabeli Silva Barroso Marcelo Henrique Salviano de Faria Heliana de Barros Fernandes Aline Silva de miranda Hugo Cesar Martins-Costa Ana cristina Simoes e Silva Janaina Matos Moreira Albena Nunes-Silva Laboratory of Inflammation and Exercise Immunology Department of Physical EducationSchool of Physical EducationFederal University of Ouro PretoOuro PretoMGBrazil Postgraduate Program in Health and Nutrition Nutrition SchoolFederal University of Ouro PretoOuro PretoMGBrazil Interdisciplinary Medical Research Laboratory Faculty of MedicineFederal University of Minas GeraisBelo HorizonteMGBrazil Neurobiology Laboratory Institute of Biological SciencesFederal University of Minas GeraisBelo HorizonteMGBrazil department of Physical Education Pontifical Catholic University of Minas GeraisBrazil department of Pediatrics Faculty of MedicineFederal University of Minas Gerais(UFMG)Belo HorizonteMGBrazil

Obesity has a complex multifactorial etiology and is characterized by excessive accumulation of adipose *** adipose tissue has deleterious effects on health because it secretes large amounts of inflammatory *** calorie restriction associated with strength training may be useful in managing chronic systemic *** study aimed to evaluate the acute effect of a single strength-training session on plasma adipokine levels in sedentary,overweight,and obese young *** study included twelve men(Age:[34.95±9.77]years;Height:[174.16±3.66]centimeter[cm];Weight:[97.83±12.87]kilogram(kg);body mass index[BMI]:[32.30±4.51]kg/m2),who performed a single strength training *** strength training protocol consisted of 4 sets of 12 repetitions in the following six exercises,45°leg press,bench press,leg extension,machine row,leg curl,and shoulder *** samples were collected before,immediately after,and 1-h subsequent after strength *** plasma levels of resistin and leptin were measured.A significant decrease in resistin levels were found 1 h after the strength training session if compared to levels before the training session(pre-[before][2390±1199]picograms per milliliter[pg/mL]vs post-1 h[1-h subsequent][1523±798],6 pg/mL,p=0.0028).The plasma leptin levels did not differ at any time *** conclusion,a very well controlled single session of strength training significantly decreased the plasma levels of resistin without altering the concentration of leptin in overweight and obese *** effect,at least in part,supports the benefits of exercise by reducing the low grade inflammation and insulin resistance in obesity.

关键词： Strength training Adipose tissue Obesity Chronicinflammation Resistin Leptin

Fraud investigation in commercial coffee by chromatography

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Food Quality and Safety 2018年第3期2卷 121-133页

作者： Víctor de Carvalho Martins Ronoel Luiz de Oliveira Godoy Ana cristina miranda Senna Gouvêa Manuela cristina Pessanha de Araujo Santiago Renata Galhardo Borguini Elaine cristina de Oliveira Braga Sidney Pacheco Luzimar da Silva de Mattos do Nascimento departamento de Tecnologia de Alimentos Instituto de TecnologiaUniversidade Federal Rural do Rio de JaneiroCEP 23890-000Seropédica-RJBrazil Laboratório de Cromatografia Líquida Embrapa Agroindústria de AlimentosCEP 23020-470Rio de Janeiro-RJBrazil Centro de Tecnologia Instituto de QuímicaUniversidade Federal do Rio de JaneiroCEP 22290-180Rio de Janeiro-RJBrazil

Coffee is currently the second largest commodity on the world market today,and there is great concern about the quality of the beans exported from producer countries to Europe and *** such as using blends of different species and adding low-cost raw materials,such as chicory,corn,and soybean,impair the sensory and functional characteristics of the drink made from roasted and ground coffee *** is a need to adopt more efficient analytical methods than the microscopy technique currently *** first chromatographic method used to determine fraud was reported in *** method used paper chromatography to differentiate between coffee and chicory based on the free reducing *** of the 1980s,different methods involving high-performance liquid chromatography and gas chromatography were developed in order to demonstrate geographic authenticity,distinction between species,occurrence of adulteration,and the presence of defective beans by determining the monosaccharides,oligosaccharides,tocopherols,fatty acids,volatiles,diterpenes,sterols,and phenolic substances,among *** far as the authors know,there are no papers published in the literature that have compiled such an extensive set of information about these chromatographic methods as *** the last 2 years,there has been a trend to develop analytical methods for ultra-performance liquid chromatography coupled with tandem mass spectrometry to confirm fraud in coffee,due to high sensitivity and selectivity.

关键词： adulteration coffee chromatographic methods carbohydrates volatile substances

Hydrological variability and long-term floristic-structural modifications in different habitats of a tropical semi-deciduous forest

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Journal of Forestry Research 2022年第3期33卷 801-811页

作者： Alisson Borges miranda Santos Vinicius Andrade Maia Cléber Rodrigo de Souza Natália de Aguiar-Campos Aurélio de Jesus Rodrigues Pais Wilder Bento da Silva Nathalle Cristine alencar Fagundes Jean Daniel Morel Rubens Manoel dos Santos department of Forestry Sciences Federal University of LavrasCampus UniversitárioC.P.3037LavrasBrazil Faculty of Environmental Engineering and Natural Resources Zambeze UniversityChimoioC.P.2400Mozambique Biological Sciences Universidade do Estado de Minas GeraisUnidade ItuiutabaAv.Antônio Carlos 6627Ituiutaba31270-901Brazil department of Biology Federal University of LavrasUniversity campusC.P.3037Lavras37200-000Brazil

Shifts in hydrological regimes alter river flow rates and flood pulses, decrease environmental heterogeneity and the floristic-structural complexity of associated plant communities. We tested the hypothesis that drought events affect plant community composition and structure at a small-scale within a riparian fragment towards a reduction in floristic-structural complexity. The tree community was sampled in three habitats (wet, transitional and dry) and monitored in seven inventories carried out between 1991 and 2018. Hydrological variations were evaluated through annual rainfalls, river flow rates and water level data. The species richness and the detrended correspondence analysis axes were used to characterise the temporal modifications in floristic composition. Community structure was described in terms of biomass: accumulated, growth of survivors, mortality and recruitment. Generalised linear mixed models were fitted to evaluate the effects of time and environment in community. It was concluded that the climate has become drier in recent years due to declining precipitation that has affected flow rates and water levels. The floristic-structural complexity of the study fragment was maintained during the monitoring period. However, prolonged and extreme drought events displayed the potential to impact floristic-structural patterns.

关键词： Forest dynamics Climate changes Semi-deciduous seasonal forest Temporal change Functioning communities

Serum levels of angiotensin converting enzyme as a biomarker of liver fibrosis

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World Journal of Gastroenterology 2017年第48期23卷 8439-8442页

作者： Aline Silva miranda Ana cristina Sim?es e Silva In-terdisciplinary Laboratory of Medical Investigation Faculty of MedicineFederal University of Minas Gerais Laboratory of Neurobiology Department of MorphologyInstitute of Biological SciencesFederal University of Minas Gerais department of Pediatrics Faculty of MedicineFederal University of Minas Gerais

The renin angiotensin system(RAS) is classically conceived as a circulating hormonal system involved in blood pressure control and hydroelectrolyte balance. The discovery that RAS components are locally expressed in a wide range of organs and tissues,including the liver,pointed to a role for this system in the pathogenesis of several conditions including hepatic fibrosis and cirrhosis. It has been widely reported that the classical RAS axis composed by the angiotensin converting enzyme(ACE)-angiotensin(Ang) Ⅱ-Ang type 1(AT1) receptor mediates pro-inflammatory,pro-thrombotic,and pro-fibrotic processes. On the other hand,the alternative axis comprising ACE2-Ang-(1-7)-Mas receptor seems to play a protective role by frequently opposing Ang Ⅱ action. Chronic hepatitis B(CHB) is one of the leading causes of liver fibrosis,accounting for the death of nearly one million people worldwide. Liver fibrosis is a key factor to determine therapeutic interventions for patients with CHB. However,the establishment of non-invasive and accurate methods to detect reversible stages of liver fibrosis is still a challenge. In an elegant study published in the 36 th issue of the World Journal of Gastroenterology,Noguchi et al showed the predictive value of serum ACE levels in detecting not only advanced stages of liver fibrosis but also initial and intermediate fibrotic stages. The serum levels of ACE might represent an accurate,non-invasive,widely available,and easy method to evaluate fibrosis related to CHB. Moreover,therapies involving the inhibition of the classical RAS axis components might be promising in the control of CHB-related liver fibrosis.

关键词： Renin angiotensin system Angiotensin converting enzyme Angiotensin Ⅱ Angiotensin-(1-7) Chronic hepatitis B hepatic cirrhosis Liver fibrosis

Selection signatures in Canchim beef cattle

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Journal of Animal Science and Biotechnology 2017年第1期8卷 15-23页

作者： Ismael Urbinati Nedenia Bonvino Stafuzza Marcos Túlio Oliveira Tatiane cristina Seleguim Chud Roberto Hiroshi Higa Luciana Correia de Almeida Regitano Maurício Mello de alencar Marcos Eli Buzanskas Danísio Prado Munari departamento de Ciencias Exatas Univ Estadual PaulistaFaculdade de Ciencias Agrairias e VeterinairiasjaboticabalSao Paulo 14884-900Brazil departamento de Tecnologia UNESP-Univ Estadual PaulistaFaculdade de Ciencias Agrarias e VeterinariasJaboticabalSao Paulo 14884-900Brazil Embrapa Agricultural Informatics CampinasSao Paulo 13083-886Brazil Embrapa Southeast Livestock Sao CarlosSao Paulo 13560-970Brazil

Background： Recent technological advances in genomics have allowed the genotyping of cattle through single nucleotide polymorphism（SNP） panels. High-density SNP panels possess greater genome coverage and are useful for the identification of conserved regions of the genome due to selection, known as selection signatures（SS）. The SS are detectable by different methods, such as the extended haplotype homozygosity（EHH）; and the integrated haplotype score（i HS）, which is derived from the EHH. The aim of this study was to identify SS regions in Canchim cattle（composite breed）, genotyped with high-density SNP ***： A total of 687,655 SNP markers and 396 samples remained for SS analysis after the genotype quality control. The i HS statistic for each marker was transformed into pi HS for better interpretation of the *** BTA5 and BTA14 showed pi HS 〉 5, with 39 and nine statistically significant SNPs（P 〈 0.00001）,respectively. For the candidate selection regions, i HS values were computed across the genome and averaged within non-overlapping windows of 500 Kb. We have identified genes that play an important role in metabolism,melanin biosynthesis（pigmentation）, and embryonic and bone ***： The observation of SS indicates that the selection processes performed in Canchim, as well as in the founder breeds（i.e. Charolais）, are maintaining specific genomic regions, particularly on BTA5 and BTA14. These selection signatures regions could be associated with Canchim characterization.

关键词： Composite breed Extended haplotype homozygosity Genomics Single nucleotide polymorphism

Diagnostic criteria for autoimmune hepatitis in children: A challenge for pediatric hepatologists

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World Journal of Gastroenterology 2012年第33期18卷 4470-4473页

作者： Priscila Menezes Ferri Alexandre Rodrigues Ferreira Débora Marques miranda Ana cristina Sim■es e Silva Division of Pediatric Gastroenterology and Hepatology Department of Pediatrics School Medicine Federal University of Minas Gerais Minas Gerais 30130-100 Brazil National Institute of Science and Technology of Molecular Medicine Faculty of Medicine Federal University of Minas Gerais Minas Gerais 30130-100 Brazil

Autoimmune hepatitis (AIH) is a progressive inflammatory liver disorder that is rare in children and adolescents. AIH has a broad clinical spectrum and a quick response to treatment with corticosteroids and immunosuppressive medication. The available diagnosis criteria have limitations and should be evaluated in pediatric populations. Recently, some studies reported that the 2008 simplified diagnostic criteria for AIH could be used in children with high sensibility and specificity. In addition, the authors reported that globulin and immunoglobulin G levels can be used interchangeably for diagnostic purposes. They also demonstrated that the 2008 simplified criteria fail in identifying patients with fulminant hepatic failure. Here, we discuss the limitations of the use of these criteria in pediatric patients and the requirement of more studies to improve the diagnosis of AIH in children.

关键词： Child Autoimmune hepatitis Liver diseases Diagnosis Autoimmunity

Hepatitis E:A Literature Review

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Journal of Clinical and Translational Hepatology 2017年第4期5卷 376-383页

作者： Juliana Ayres de alencar Arrais Guerra Katia cristina Kampa Daphne Gon(c)alves Benatti Morsoletto Alcindo Pissaia Junior Cláudia Alexandra Pontes Ivantes Nossa Senhora das Gracas Hospital Alcides Munhoz Street433-MercêsCuritiba-PRBrazil

Hepatitis E is the fifth known form of human viral *** not very common in our clinical practice,the incidence in Western countries is *** with the hepatitis E virus(HEV)may be related to acute illness,liver failure,chronic hepatitis and *** itself is an RNA virus,with eight described genotypes(HEV 1-8),four of which more commonly affect humans and have,thus,been better *** liver manifestations,genotype 3 is also related to extra-hepatic manifestations,such as neurological,renal and *** to chronic disease occurs especially in patients who underwent transplantation,have hematological malignancies requiring chemotherapy,or have infection with the human immunodeficiency *** diagnosis may be difficult because of the low availability of tests and due to low sensibility and *** acute form of illness does not have to be treated,but the chronic one *** present here a literature review of hepatitis E and the relation between chronic hepatitis E and transplantation.

关键词： Hepatitis E Chronic hepatitis E Immunosuppression Transplantation

Renin angiotensin system in liver diseases: Friend or foe?

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World Journal of Gastroenterology 2017年第19期23卷 3396-3406页

作者： Ana cristina Simoes e Silva Aline S miranda Natália P Rocha Antonio L Teixeira department of Pediatrics Faculty of MedicineFederal University of Minas Gerais Interdisciplinary Laboratory of Medical Investigation Faculty of MedicineUFMG Laboratory of Neurobiology Department of MorphologyInstitute of Biological SciencesUFMG Neuropsychiatry Program Department of Psychiatry and Behavioral SciencesMcGovern Medical SchoolUniversity of Texas Health Science Center at Houston

In the last three decades,the understanding of the renin angiotensin system(RAS)has been changed by the discoveries of functional local systems,novel biologically active peptides,additional specific receptors,alternative pathways of angiotensin(Ang)?Ⅱ?generation,and new roles for enzymes and precursor components other than those in Ang?Ⅱ?*** this regard,the discovery that Ang-(1-7)opposes the pressor,proliferative,pro-fibrotic,and pro-inflammatory effects mediated by Ang?Ⅱ?has contributed to the realization that the RAS is composed of two *** first axis consists of the angiotensin-converting enzyme(ACE),with Ang?Ⅱ?as the end product,and the angiotensin type 1(AT1)receptor as the main effector mediating the biological actions of Ang?Ⅱ.The second axis results from ACE2-mediated hydrolysis of Ang?Ⅱ,leading to the production of Ang-(1-7),with the Mas receptor as the main effector conveying the vasodilatory,antiproliferative,anti-fibrotic,and anti-inflammatory effects of Ang-(1-7).Experimental and clinical studies have shown that both axes of the RAS may take part in the pathogenesis of liver *** this manuscript,we summarize the current evidence regarding the role of RAS in hepatic cirrhosis and its complications,including hemodynamic changes and hepatorenal *** therapeutic potential of the modulation of RAS molecules in liver diseases is also discussed.

关键词： Renin angiotensin system Angiotensin Ⅱ Angiotensin-(1-7) Hepatic cirrhosis Liver fibrosis Hepatorenal syndrome

Potential strategies offered by animals to implement in buildings' energy performance: Theory and practice

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Frontiers of Architectural Research 2019年第1期8卷 17-31页

作者： Cesar Martin-Gomez Amaia Zuazua-Ros Javier Bermejo-Busto Enrique Baquero Rafael miranda cristina Sanz department of Building Construction Building Services and Structures Universidad de Navarra Pamplona 31009 Spain School of Sciences Department of Environmental Biology Universidad de Navarra Pamplona 31080 Spain

The strategies for thermal regulation and envir on mental control found in nature are countless. In this article, a parallelism between animals and building energy systems is defined in order to identJfy and emphasize the immediate opportunities that biomimicry offers for future research. The motivation was the need to find alternative solutions to tackle problems mainly in the efficiency of heating, ventilation and cooling systems. Due to the wide range of possibilities offered by animals, this study is largely limited to the strategies that cold-blooded animals have developed through evolutionary adaptation to the environment. The method used for the an a lysis is based on a soluti on-based approach. Firstly, differe nt animal thermoregulation strategies are defined (biological domain). Then the strategy is an a lyzed and classified into three categories. This classification is esse ntial in order to formulate the parallelism with building systems (transfer phase). The final step is to identify the potential implementation (technological domain).This approach has been seen to be useful in creating new research opportunities based on biomimicry. In addition, suitable solutions arising from multidisciplinary team research are presented as promising answers to the challenges that building energy systems face no wadays.

关键词： Biomimicry Building services Energy systems Passive design Multidisciplinary