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Neurological and behavioral manifestations of cerebral malaria:An update

World Journal of Translational Medicine 2014年第1期3卷 9-16页

作者： Marta Chagas Monteiro Fabio Rodrigues Oliveira Gedeo Batista Oliveira Pedro Roosevelt Torres Romo cristiane socorro ferraz maia Programa de Pós-Gradua??o em Ciências Farmacêuticas Instituto de Ciências da Sau?deUniversidade Federal do ParáRua Augusto CorrêaCampus Universitário do GuamáBelémPA 66075900Brazil Program in Pharmaceutical Sciences Faculty of Pharmacy Laboratory of inflammation and behavior Federal University of Pará/UFPABelémPA 66075900Brazil Programa de Pós-Gradua??o em Ciências da Saúde Universidade Federal de Ciências da Saúde de Porto AlegrePorto AlegreRS 90050170 Brazil

Neglected tropical diseases are a group of tropical diseases endemic in poor countries even though medical treatment and cures are available. They are considered a global health problem due to the severity of the physiological changes they induce in their hosts. Malaria is a disease caused by Plasmodium sp. that in its cerebral form may lead to acute or long-term neurological deficits, even with effective antimalarial therapy, causing vascular obstruction, reduced cerebral blood flow and many other changes. However, Plasmodium falciparum infection can also develop into a cerebral malaria(CM) disease that can produce neurological damage. This review will discuss the mechanisms involved in the neuropathology caused by CM, focusing on alterations in cognitive, behavior and neurological functions in human and experimental models.

关键词： Malaria Cerebral malaria Neuropathology Plasmodium sp Plasmodium falciparum

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Case report of a criminal dismemberment in Northeast Brazil

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Forensic Sciences Research 2022年第4期7卷 637-642页

作者： Evelyne Pessoa Soriano Maria do socorro Dantas de Araújo Francisca de Assis Nascimento Pereira Francisca Divina Silveira de Melo cristiane Helena da Silva Barbosa Freire Marcus Vitor Diniz de Carvalho Medico-legal Institute of João Pessoa ParaíbaBrazil Faculty of Dentistry(FOP) Center for Studies in Forensic Anthropology(CEAF)University of Pernambuco(UPE)RecifeBrazil

Several decomposed body parts were received for examination by the Forensic Anthropology section of the Medico-legal Institute of João Pessoa,Paraíba,*** portions of the lower and upper limbs,ribs,vertebrae,and a skull were thoroughly *** biological profile indicated a male individual with an estimated age range between 23 and 57 years and a mean age of 35.2 years(SD=9.4;phase IV,Suchey-Brooks).The skeleton showed injuries caused by sharp force and sharp-blunt force trauma that affected all body ***,the lesions are mainly in the diaphyseal segments of the long bones,sacrum,pelvis,mandible,maxilla,scapulae,sternum,vertebrae,the distal epiphysis of the left fibula,and the distal epiphysis of the left tibia displayed characteristics compatible with injuries produced *** was not possible to determine the cause of *** resulted in a positive *** of common difficulties faced in forensic practice,it is often not possible for forensic anthropologists to go to the crime scene,X-ray or body scanners are frequently unavailable,and the victim’s medical and/or dental records are sometimes *** difficulties make identification ultimately depend on genetic analysis,which is more time-consuming than other identification *** this,bone fragment examination in dismemberment cases is a complex *** Anthropology can shed light on cases involving the identification of dismembered remains,which are challenging because of the number of traumatic injuries,as well as different injury patterns,on bones.

关键词： Forensic sciences forensic anthropology dismemberment human identification

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