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Intelligent speed adaptation for visibility technology affects drivers’speed selection along curves with sight limitations

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Journal of Traffic and Transportation Engineering(English Edition) 2024年第1期11卷 16-27页

作者： Abrar Hazoor Alberto Terrafino Leandro L.Di Stasi Marco bassani Department of Environment Landand Infrastructure EngineeringPolitecnico di TorinoTorino 10129Italy Road Traffic Division Nord UniversityStjørdal 7502Norway Mind Brainand Behavior Research Centre(CIMCYC)University of GranadaGranada 18071Spain

Sight obstructions along road curves can lead to a crash if the driver is not able to stop the vehicle in *** is a particular issue along curves with limited available sight,where speed management is necessary to avoid unsafe situations(e.g.,driving off the road or invading the other traffic lane).To solve this issue,we proposed a novel intelligent speed adaptation(ISA)system for visibility,called V-ISA(intelligent speed adaptation for visibility).It estimates the real-time safe speed limits based on the prevailing sight conditions.V-ISA comes with three variants with specific feedback modalities(1)visual and(2)auditory information,and(3)direct intervention to assume control over the vehicle ***,we investigated the efficiency of each of the three V-ISA variants on driving speed choice and lateral behavioural response along road curves with limited and unsafe available sight distances,using a driving *** also considered curve road geometry(curve direction:rightward ***).Sixty active drivers were recruited for the *** half of them(experimental group)tested the three V-ISA variants(and a V-ISA off condition),the other half always drove with the V-ISA off(validation group).We used a linear mixed-effect model to evaluate the influence of V-ISA on driver *** V-ISA variants were efficient at reducing speeds at entrance points,with no discernible negative impact on driver lateral *** rightward curves,the V-ISA intervening variant appeared to be the most effective at adapting to sight *** of the current study implies that V-ISA might assist drivers to adjust their operating speed as per prevailing sight conditions and,consequently,establishes safer driving conditions.

关键词： Sight distance Intelligent speed adaptation Driver behaviour Road safety Driving simulation Advanced driver assistance systems

Experimental analysis of operational data for roundabouts through advanced image processing

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Journal of Traffic and Transportation Engineering(English Edition) 2020年第4期7卷 482-497页

作者： Marco bassani Lorenzo Mussone Department of Environment Land and Infrastrwcture EngineeringPolitecnico di TorinoTorino 10129Italy Department of Architecture Built Environment and Construction EngineeringPolitecnico di MilanoMilano 20133Italy

Roundabout is still the focus of several investigations due to the relevant number of variables affecting their operational performances(i.e.,capacity,safety,emissions).To develop reliable models,investigations should be supported by devices and relate d sensors to extract variables of interest(i.e.,flow,speed,gap,lag,follow-up time,vehicle classification and trajectory).Notwithstanding that several sensors and technolo gies are currently used for data collection,most of them present *** paper presents the investigation carried out to survey vehicle movem ents at roundabouts as a comprehensive video image analysis system is able to derive the origin/destination(O/D)matrix,compile a vehicle classification,track individual vehicle trajectories together with corresponding speeds and accelerations along *** this end,the authors collected video-sequences that were analysed with a piece of software developed for that *** minimize the problems due to perspective distortion,environmental effects,and obstructions,a number of camera set-up configurations were adopted with equipment being placed on central or external poles,and on permanent fixtures such as raised working platforms outside the confines of the intersection *** of those installation set-ups with different vehicle tracking strategies has been ***,speed has been successfully related to trajectory tortuosity,the result of which emphasizes the tremendous potential of image analysis and opens up to further studies on the evaluation of the operational effects of roundabout geometrics.

关键词： Transportation Roundabout Image analysis/processing Vehicle tracking and classification Operating speed Trajectory

PCDH19 interplay with GABA(A)receptors:a window to DEE9 pathogenetic mechanisms

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Neural Regeneration Research 2022年第4期17卷 803-805页

作者： Sara Mazzoleni Silvia bassani Institute of Neuroscience CNRMilanItaly Department of Medical Biotechnology and Translational Medicine University of MilanSegrate(MI)Italy NeuroMI Milan Center for Neuroscience University of Milano-BicoccaMilanItaly

Developmental and epileptic encephalopathy 9(DEE9):The gene PCDH19(Xq22.1),which encodes the calcium-dependent cell adhesion protein protocadherin-19(PCDH19),is nowadays considered as one of the most important genes in monogenic epilepsy(Depienne and LeGuern,2012).Mutations in PCDH19 are responsible for DEE9(OMIM#300088),a severe neurodevelopmental disorder characterized by early-onset clustering epilepsy,various degrees of cognitive impairment and neuro psychiatric comorbidities,like autism spectrum disorder(ASD)and behavioural ***9 patients start suffering from seizures around the age of 10 months until adolescence,when seizures tend to reduce or even disappear,while the psychiatric symptoms persist(Depienne and LeGuern,2012;Kolc et al.,2018).

关键词： H19 PCD epilepsy

Proof of concept of a self-tightening needle-less suture using a NiTi shapememory alloy

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生物设计与制造(英文) 2023年第5期6卷 536-549页

作者： Adelaide Nespoli Davide Ninarello Enrico bassani Villiam Dallolio Institute of Condensed Matter Chemistry and Technologies for Energy National Research Council(CNR-ICMATE)23900 LeccoItaly Promev Srl 23900 LeccoItaly

Among surgical procedures,suturing is considered ***,in some situations,suturing is not easy or ***,we present proof of concept of a new self-tightening needle-less suture made of a NiTi *** new device is designed to overcome two demanding steps of traditional suturing:needle introduction and manual *** novel suture is composed only of a short NiTi wire that is able to change shape by exploiting a thermoelastic phase *** shape change is achieved by increasing the temperature from that of the operating room(e.g.,20-22℃)to 32℃using warm *** consists of two steps:suture introduction,in which the suture is in an open configuration,and shape recovery(i.e.,closed configuration).The closed configuration is maintained at human body temperature thanks to peculiar pseudoelastic properties of the NiTi ***,thermal and functional characterization verified the simplicity and effectiveness of the proposed device.

关键词： Suture NiTi Shape memoryalloys Suturing Medical device

Video-Assisted Anterior Retroperitoneal Approach to the Lumbar Spine. A Minimal Invasive Technique Improved by the Use of Endoscopic Camera to Treat Lumbar Spine Diseases

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International Journal of Clinical Medicine 2016年第1期7卷 94-100页

作者： Roberto bassani Riccardo Cecchinato Carlotta Morselli Pedro Berjano Claudio Lamartina IRCCS Galeazzi Orthopedic Institute Milan Italy Department of Neurosurgery and Gamma Knife Radiosurgery San Raffaele Hospital Vita-Salute University Milan Italy

The anterior retroperitoneal approach is a technique to treat disc degenerative disease (DDD), spinal deformities, traumas, tumors and infections. It can be used to perform Anterior Lumbar Interbody Fusions (ALIF) or Total Disc Replacements (TDR). Though being a fast procedure that is becoming more often used by spinal surgeons, the anterior approach requires an adequate knowledge of the anatomy of the abdomen to lessen the risks of intraoperative complications. The authors’ preferred technique is the left retroperitoneal video-assisted approach, using an endoscope to visualize and magnify the deep anatomical structures, discectomy procedure and hardware implant. In a review of our casuistry from 2010 to 2012, 163 patients underwent an anterior lumbar approach, and 139 of these had a single L4-5 or L5-S1 level treatment. A 3.6% rate of global complications (1.44% of major vascular injuries) has been observed, with a mean operation time of 116.4 minutes and a mean blood loss of 156.1 ml. These values show how the anterior retroperitoneal video-assisted approach for the treatment of lumbar diseases is a fast procedure that implies low blood loss, with a low rate of intraoperative complications.

关键词： Video-Assisted Anterior Retroperitoneal Approach ALIF TDR

C-MET Inhibitors as New Members of the NSCLC Treatment Armamentarium—A Pooled Analysis

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Advances in Lung Cancer 2022年第1期11卷 1-13页

作者： Susanne Reuther Niccolo bassani Michael F. Murphy Wolfram Dempke University Clinic LMU Munich Munich Germany Worldwide Clinical Trials Nottingham UK

Objective: Capmatinib and tepotinib, two recently FDA-approved and highly specific small-molecule inhibitors of c-MET exon 14 skipping mutations are new and important therapeutic options for the treatment of NSCLC patients harbouring c-MET alterations. However, the precise role of these molecules as a new treatment option is still not fully defined. Methods: In an attempt to further evaluate the contributions of c-MET inhibitors to the armamentarium of treatment options for advanced and metastatic NSCLCs, relevant phase II and III studies were retrospectively analyzed in terms of ORR and mPFS (mOS numbers are still not available for current c-MET trials and therefore not considered for statistical purposes). Results: Treatment of advanced and metastatic NSCLC patients harbouring c-MET exon 14 skipping mutations with the novel and highly selective c-MET inhibitors is significantly superior (p Conclusion: The novel and highly selective c-MET inhibitors capmatinib and tepotinib are promising novel treatment options for patients with c-MET-dysregulated NSCLC primarily in the first-line setting, albeit a clear mOS benefit has not yet been established. Since immunotherapy did not appear to be particularly effective in NSCLC patients harbouring c-MET alterations, the vast majority of these patients are treated with immunotherapy plus chemotherapy. C-Met inhibitors appear to be equally effective and thereby sparing patients from the toxic effects of the chemotherapy. The routine testing of c-MET exon 14 skipping mutations should be performed as the GEOMETRY mono-1 data clearly showed higher response rates with capmatinib in treatment-naive than in pretreated patients, indicating that c-MET exon 14 skipping mutations should preferably be molecularly assessed at baseline. C-MET exon 14 skipping mutations are, therefore, clear biomarkers of response to c-MET inhibitors.

关键词： NSCLC Treatment Options c-MET Inhibitors Statistical Analysis

The hydrogen atom: precision physics 1

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Root Canal Treatment Outcome and Restorative Condition of Teeth Treated by Undergraduates—A Clinical and Radiographic Evaluation

丛书名： LNP0570

2001年

作者： S.G. Karshenboim F.S. Pavone F. bassani M. Inguscio T.W. Hänsch

来源：畅想之星图书光盘版（南... 评论

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Open Journal of Stomatology 2023年第9期13卷 257-270页

作者： Gabriela Tonet bassani Bartelle Dianeia Miranda dos Reis Thiago Oliveira Gamba Fabiana Vieira Vier-Pelisser School of Dentistry UCS—Caxias do Sul University Caxias do Sul Brazil School of Dentistry UFRGS—Federal University of Rio Grande do Sul Porto Alegre Brazil

Background: The aim was to evaluate the nonsurgical Root Canal Treatment (nRCT) outcome, the restorative condition and the relationship between the coronal restoration quality and the outcome of teeth endodontic treated by undergraduates at the University of Caxias do Sul School of Dentistry (UCS-SD), Brazil, between 2019 and 2021. Materials and Methods: Data from the endodontically treated cases were retrieved, and the patients were recalled for a follow-up appointment at the university. The endodontic diagnosis, radiographs, and the presence of definitive restorations were analyzed in the clinical records. During the follow-up appointment, endodontically treated teeth were classified as present or absent. The nRCT was classified as successful (complete or incomplete healing) or failure (uncertain or unsatisfactory healing). Coronal restoration was classified as absent or present. When it was present, it was classified as permanent or temporary, and its quality as adequate or inadequate restoration. The results were presented as percentages. Results: A total of 257 teeth were endodontically treated. The most prevalent diagnosis was Chronic Apical Periodontitis (33.33%) and the most commonly treated teeth were premolars (46.15%). A total of 52 (21%) treated teeth were clinically and radiographically reexamined. The success rate for the nRCT was 98.08%. About 61.54% of this sample had a definitive composite resin restoration. Conclusion: The nRCT success rate was high. Special attention should be given to the presence and quality of the definitive restoration. Clinical Implications: There was no statistically significant impact between the coronal restoration and the nRCT success (P > 0.05).

关键词： Periapical Periodontitis Permanent Dental Restoration Permanent Dental Filling Root Canal Obturation Treatment Outcome

Testing the Use of Coconut Fiber as a Cushioning Material for Transport Packaging

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Materials Sciences and Applications 2012年第3期3卷 151-156页

作者： Clívia D. Pinho da Costa Castro José de Assis Fonseca Faria Tiago bassani Hellmeister Dantas Centre for Packaging Technology-ITAL Campinas Brazil Faculty of Food Engineering University of Campinas-UNICAMP Campinas Brazil

In spite of being a raw material of virtually unlimited availability due to the massive consumption of the highly popular coconut water, fiber produced from green coconut is much less used than the dried coconut fiber. The objective of this study was to investigate the performance of green (white) coconut fiber as a cushioning material for use in packaging systems. The mechanical performance of both green coconut fibers in their natural state as well as those molded into the shape of cushioning pads were evaluated by shock absorption tests. The results showed that the fibers without agglutination agents exhibited the best performance when submitted to increasing static loads by presenting the greatest capacity to reduce impact acceleration. In addition, green coconut fiber presented behavior similar to that of cellulosic cushioning materials and in certain situations can be considered effective in protecting products that are considered fragile.

关键词： Coconut Fiber Impact Cushioning