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Renal function and choroidal thickness using swept-source optical coherence tomography in diabetic patients

International Journal of Ophthalmology(English edition) 2019年第6期12卷 985-989页

作者： Antonio Manuel Garrido-Hermosilla Mariola Méndez-Muros Estanislao Gutiérrez-Sánchez cristóbal morales-portillo María Jesús Díaz-GrANDa Eduardo Esteban-González Isabel Relimpio-López María Asunción Martínez-Brocca Enrique Rodríguez-de-la-Rúa-Franch Department of Ophthalmology Virgen Macarena University HospitalSeville 41009Spain OftaRed Institute of Health Carlos IIIMadridSpain Department of Endocrinology and Nutrition Virgen Macarena University HospitalSeville 41009Spain

AIM: To assess the relationship between choroidal thickness and renal function in diabetic patients. METHODS: Cross-sectional retrospective clinical study of 42 eyes of 21 ocular treatment-na?ve diabetic patients. Demographic data included: age, sex, type and course of diabetes. Ocular data included: severity of diabetic retinopathy;retinal thickness at the central macular region, as well as choroidal thickness at the central and paracentral quadrants, using automatically generated maps by swept-source optical coherence tomography;presence of cystic macular edema;and ocular axial length(AXL). Lab-test parameters included: glycated hemoglobin(HbA1c), albuminuria, albumin/creatinine ratio in urine, and glomerular filtration rate. RESULTS: A significant negative correlation was mainly observed between several choroidal thicknesses, age(P<0.020) and ocular AXL(P<0.030). On the contrary, a significant positive correlation was found between all choroidal thicknesses, HbA1 c(P<0.035) and albuminuria(P<0.040). CONCLUSION: Choroidal thickness can represent an additional tool to help clinicians predicting the renal status in ocular treatment-na?ve diabetic patients.

关键词： choroidal thickness renal function swept-source optical coherence tomography spectral-domain optical coherence tomography diabetes mellitus

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Diabetes and Periodontal Diseases: An Established Two-Way Relationship

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Journal of Diabetes Mellitus 2016年第4期6卷 209-229页

作者： Carlos Arana Molina Luna Florencio Ojeda María Sevillano Jiménez cristóbal morales portillo Isabel Serrano Olmedo Tomás Martín Hernández Gerardo Gómez Moreno Department of Endocrinology and Nutrition Virgen Macarena University Hospital Seville Spain Department of Special Care in Dentistry Pharmacological Research in Dentistry Group Faculty of Dentistry University of Granada Granada Spain

Background: Periodontal diseases (PD), including periodontitis, are chronic inflammatory pathologies caused by bacteria in the subgingival biofilm which affect the periodontal tissues. PD is now considered a localized, chronic, oral infection that activates the host immuno-inflammatory responses both locally and systemically, and also constitutes a source of bacteraemia. It is a known fact that periodontal diseases exercise an important influence on the pathogenesis of numerous systemic diseases, including diabetes mellitus (DM). In the mid-nineties, sufficient scientific evidence emerged to confirm an association between DM and periodontitis, which then began to be regarded as the sixth complication of DM. Current scientific evidence points to a two-way relationship between DM and periodontal disease, whereby DM is associated with an increase in the incidence and progression of periodontitis, while periodontal infection is associated with worsening glycemic control in diabetic patients. This two-way relationship points to a need to promote oral health in DM patients, and to implement a joint management protocol between endocrinologist and dentist that aims to create adequate conditions for early diagnosis and the effective treatment of both diseases.

关键词： Diabetes Mellitus Periodontitis Periodontal Medicine Two-Way Relationship

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Properties of Chemical Bath Deposited PbS Thin Films Doped with Cd2＋

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材料科学与工程（中英文A版） 2011年第6期1卷 759-767页

作者： Oscar portillo Moreno Melissa Chavez portillo Miriam Moreno Flores Javier Martinez Juarez Gustavo Abarca Avila Rosendo Lozada morales Orlando Zelaya Angel Facultad de Ciencias Quimicas BUAP C. U. Puebla Mexico CIDS-ICUAP C. U. Puebla Mexico Facultad de Ciencias Fisicomatematicas BUAP C. U. Puebla Mexico Departamento de Fisiea Centro de Investigacion y de Estudios Avanzados Av. IPN 2508 Col San Pedro Zacatenco Mexico

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Characterization of Chemical Bath Deposited CdS, CdSe and PbS

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材料科学与工程（中英文A版） 2011年第5X期1卷 692-704页

作者： Oscar portillo Moreno Gustavo Abarca Avila Jorge R. Cerna Juan Hernandez Tecorralco Melissa Chavez portillo Javier Martinez Juarez Rosendo Lozada morales Orlando Zelaya Angel Facultad de Ciencias Quimicas Benemerita Universidad Autonoma de Puebla Mexico Col. Sn. Manuel Puebla Pue. Mexico CIDS-ICUAP Benemerita Universidad Autonoma de Puebla Mexico. Col. Sn. Manuel Puebla Pue. Mexico Fac. Ciencias Fisicomatematicas Postgrado en Optoelectronica Benemerita Universidad Autonoma de Puebla Mexico Col. Sn Manuel Puebla Pue. Mexico Departamento de Fisica Centro de Investigacion y de Estudios de Estudios Avanzados del IPN 07360 Mexico D. F. Mexico

CdS, CdSe and PbS films were grown onto glass by chemical bath deposition (CBD). Different constant deposition temperatures (Td) were employed in the range 0-80 °C with subintervals of 10 °C. Concentration of reagents, pH, and stirring were maintained constants. A microcrystalline mixture CdCO3 and CdS were grown. At intermediates Td values a mixture of both materials present. i. e., For Td? 40 °C, the intensity of the main of X-ray Diffraction (XRD) CdS peak is abruptly reduced. By scanning electronic microscopy (SEM) with Td = 80 °C, concentration atomic: Cd = 49.10, S = 51.90, for Td? 70 °C, increase of carbon and oxygen. The CdSe, average grain size (GS) increased monotonic with Td, reaching saturation of 70 °C, with GS values of 5-16 nm. At low Td values (0-20 °C), the structural phase was found, and the high Td = 70 °C on material 5-16 nm was appreciated transition to phase: Wurzite (W)? Zinbclende (ZB) and phases mixture: W/ZB, grain size (GS) 9-27 nm. By (XRD), PbS grow in W phase at all films, for Td = 60 °C, was observed preferential orientation in plane [111] with (GS) of 19-26 nm also a Gibbs free energy calculation is included.

关键词： CdSe 化学浴沉积 PBS 平均晶粒尺寸扫描电子显微镜表征吉布斯自由能薄膜生长

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Characterization of Chemical Bath Deposited CdSe Thin Films Doped with S^2-

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材料科学与工程（中英文B版） 2011年第5期1卷 657-666页

作者： Jorge Indalecio Contreras Rascon Oscar portillo Moreno Gustavo Abarca Avila Jorge R. Cerna Juan Hernandez Tecorralco Javler Martinez Juare Rosendo Lozada morales Orlando Zelaya Angel CIDS-ICUAP Benemerita Universidad Autonoma de Puebla 14 Sur y Av. Sn. Claudio Col. Sn. Manuel Puebla Pue. Mexieo Facultad de Ciencias Quimicas Benemerita Universidad Autonoma de Puebla 14 Sur y Av. Sn. Claudio Col. Sn. Manuel Puebla Pue. Mexico Facultad de Ciencias Fisicomatematicas Postgrado en Optoelectroniea Benemerita Universidad Autonoma de Puebla 14 Sur y A v Sn. Claudio Col. Sn. Manuel Puebla Pue. Mexico Departamento de Fisiea del Centro de Investigacion y de Estudios Avanzados del IPN 07360 Mexico D. F. Mexico

CdSe thin films doped with S2-, growing on glass substrates using the chemical bath deposition (CBD) at temperature of T = 80 oC, with precursor solutions: CdCl2 0.01 M, KOH 0.1 M, 0.5 M, SeC(NH2)2 0.04 M, NH4NO3, SC(NH2)2 0.2 M, 5, 10, 15, 20, 25 and 30 mL of doping. The concentration of atoms was obtained by Scanning Electron Microscopy (SEM), S = 14.11-42.57, Cd = 49.11-59.59, and Se = 50.99-2.29, X-ray diffraction, identifies mixture of Wurzite/Zinc blende doped films phases and size of grain of 24-15 nm. Optical Absorption Spectra have redshifts of the forbidden band gap (Eg) of 1.8-2.3 eV. Raman spectra (RS) show the Raman shift, confirming formation of nanocrystals. From the dark conductivity vs. 1/kT behavior on the 100-500 K range, attributed to doping effects at the grain boundaries and quantum confinements. A thermodynamic model is proposed using the equation of Nernst to evaluate changes in the Gibbs free energy and investigate the spontaneity of reactions.

关键词：硒化镉薄膜化学浴沉积掺杂效应 CdSe 扫描电子显微镜 X射线衍射分析表征吉布斯自由能

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