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Quality of life in patients with gastroenteropancreatic tumours: A systematic literature review

World Journal of Gastroenterology 2020年第25期26卷 3686-3711页

作者： Catherine Watson craig william tallentire John K Ramage Rajaventhan Srirajaskanthan Oscar RLeeuwenkamp Donna Fountain PHMR Health Economics Pricing and ReimbursementLondon NW18XYUnited Kingdom Kings Health Partners NET centre Kings College Hospital LondonLondon SE59RSUnited Kingdom Advanced Accelerator Applications Geneva 1204Switzerland

BACKGROUND Gastroenteropancreatic neuroendocrine tumours(GEP-NETs)are slow-growing cancers that arise from diffuse endocrine cells in the gastrointestinal tract(GINETs)or the pancreas(P-NETs).They are relatively uncommon,accounting for 2%of all gastrointestinal *** usual treatment options in advanced GEP-NET patients with metastatic disease include chemotherapy,biological therapies,and peptide receptor radionuclide *** the impact of treatment on GEP-NET patients is paramount given the nature of the ***-related quality of life(HRQoL)is increasingly important as a concept reflecting the patients’perspective in conjunction with the disease presentation,severity and *** To conduct a systematic literature review to identify literature reporting HRQoL data in patients with GEP-NETs between January 1985 and November *** The PRISMA guiding principles were ***,Embase and the Cochrane library were *** extracted from the publications included type of study,patient population data(mid-gut/hind-gut/GI-NET/P-NET),sample size,intervention/comparators,HRQoL instruments,average and data spread of overall and sub-scores,and follow-up time for data *** Forty-three publications met the inclusion *** heterogeneous nature of the different study populations was evident;the percentage of female participants ranged between 30%-60%,whilst average age ranged from 53.8 to 67.0 *** studies investigated GI-NET patients only,six studies focused exclusively on P-NET patients and the remaining studies involved both patient populations or did not report the location of the primary *** most commonly used instrument was the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-C30(n=28)with consistent results across studies;the GI-NET-specific module Quality of Life Questionnaire-GINET21 was used in six of these studies.A number of randomised tria

关键词： Gastroenteropancreatic neuroendocrine tumours Health-related quality of life Systematic literature review Chemotherapy Biological therapies Peptide receptor radionuclide therapy

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Conversion of soy molasses,soy solubles,and dried soybean carbohydrates into ethanol

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International Journal of Agricultural and Biological Engineering 2013年第1期6卷 62-68页

作者： craig C.Long william R.Gibbons Biology and Microbiology Department South Dakota State UniversityBrookingsSD57007 USA

Soy molasses and soy solubles are byproducts of the conventional soy protein concentrate and soy protein isolate manufacturing processes,*** of the carbohydrates in these byproducts into ethanol was *** amounts of commercial cellulase enzymes(Novozyme cellulase,β-glucosidase,and pectinase)were added to soy molasses and soy solubles solutions prepared at various solid loading rates(33%,50%,60%,75%,and 80%)to hydrolyze oligosaccharides,followed by fermentation for 96 h using Saccharomyces cerevisiae NRRL Y-2034 and Scheffersomyces stipitis NRRL ***-extracted soybean meal(SBM)carbohydrates were also fermented for 96 h without *** and *** produced about 12.5-45.0 g/L and 6.0-28.0 g/L ethanol,respectively,on molasses and solubles across these solid loading *** *** produced about 6.5-17 g/L ethanol and *** produced about 6.5-22 g/L ethanol on ethanol-extracted carbohydrates.

关键词： ethanol production soy molasses soy solubles oligosaccharides

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Radical innovation breakthroughs of biodegradation of plastics by insects:history,present and future perspectives

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Frontiers of Environmental Science & Engineering 2024年第6期18卷 127-165页

作者： Shan-Shan Yang Wei-Min Wu Federica Bertocchini Mark Eric Benbow Suja P.Devipriya Hyung Joon Cha Bo-Yu Peng Meng-Qi Ding Lei He Mei-Xi Li Chen-Hao Cui Shao-Nan Shi Han-Jun Sun Ji-Wei Pang Defu He Yalei Zhang Jun Yang Deyi Hou De-Feng Xing Nan-Qi Ren Jie Ding craig S.Criddle State Key Laboratory of Urban Water Resource and Environment School of EnvironmentHarbin Institute of TechnologyHarbin 150090China Department of Civil and Environmental Engineering William&Cloy Codiga Resource Recovery CenterStanford UniversityStanfordCA 94305USA Plasticentropy rue Thiers 28Reims 51100France Department of Entomology and Department of Osteopathic Medical Specialties Michigan State UniversityEast LansingMI 48824USA School of Environmental Studies Cochin University of Science and TechnologyKochi 682022India Department of Chemical Engineering Pohang University of Science and TechnologyPohang 37673Republic of Korea School of Environmental Science and Engineering Tongji UniversityShanghai 200092China China Energy Conservation and Environmental Protection Group CECEP Talroad Technology Co.Ltd.Beijing 100096China School of Ecological and Environmental Sciences East China Normal UniversityShanghai 200241China Research Institute for Frontier Science Beihang UniversityBeijing 100191China School of Environment Tsinghua UniversityBeijing 100084China

Insects damaging and penetrating plastic packaged materials has been reported since the *** innovation breakthroughs of plastic biodegradation have been initiated since the discovery of biodegradation of plastics by Tenebrio molitor larvae in 2015 followed by Galleria mellonella in *** we review updated studies on the insect-mediated biodegradation of *** biodegradation by insect larvae,mainly by some species of darkling beetles(Tenebrionidae)and pyralid moths(Pyralidae)is currently a highly active and potentially transformative area of *** the past eight years,publications have increased explosively,including discoveries of the ability of different insect species to biodegrade plastics,biodegradation performance,and the contribution of host and microbiomes,impacts of polymer types and their physic-chemical properties,and responsible enzymes secreted by the host and gut *** date,almost all major plastics including polyethylene(PE),polypropylene(PP),polyvinyl chloride(PVC),polyethylene terephthalate(PET),polyurethane(PUR),and polystyrene(PS)can be biodegraded by *** and ten other insect species representing the Tenebrionidae and Pyralidae *** biodegradation processes are symbiotic reactions or performed by synergistic efforts of both host and gut-microbes to rapidly depolymerize and biodegrade plastics with hourly *** digestive ezymens and bioreagents screted by the insects play an essential role in plasatic biodegradation in certain species of Tenebrionidae and Pyralidae *** research on the insect itself,gut microbiomes,transcriptomes,proteomes and metabolomes has evaluated the mechanisms of plastic biodegradation in *** conclude this review by discussing future research perspectives on insect-mediated biodegradation of plastics.

关键词： Plastics Biodegradation Insects Gut microbiomes Enzymes

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Microplastics pollution and reduction strategies

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Frontiers of Environmental Science & Engineering 2017年第1期11卷 1-4页

作者： Wei-Min Wu Jun Yang craig S. Criddle Department of Civil and Environmental Engineering William & Cloy Codiga Resource Recovery Center Center for Sustainable Development & Global Competitiveness Stanford University Stanford CA 94305-4020 USA School of Chemistry and Environment Beihang University Beijing 100191 China

Microplastic particles smaller than 5 mm in size are of increasing concem, especially in aquatic environments, such as the ocean. Primary source is microbeads （〈 1 mm） used in cosmetics and cleaning agents and fiber fragments from washing of clothes, and secondary source such as broken down plastic litter and debris. These particles are mostly made from polyethylene （PE）, polypropylene （PP）, polystyrene （PS）, polyethylene terephthalate （PET） and polyesters. They are ingested by diverse marine fauna, including zooplanktons, mussel, oyster, shrimp, fish etc. and can enter human food chains via several pathways. Strategy for control of microplastics pollution should primarily focus on source reduction and subsequently on the development of cost-effective clean up and remediation technologies. Recent research results on biodegradation of plastics have revealed a potential for microbial biodegradation and bioremediation of plastic pollutants, such as PE, PS and PET under appropriate conditions.

关键词： microplastics plastic microbeads environmental pollution biodegradation

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Cotton Physiological Parameters Affected by Episodic Irrigation Interruption

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Journal of Agricultural Science and Technology(A) 2013年第6期3卷 443-454页

作者： Fulvio Rodriguez Simao Glen Lorin Ritchie craig william Bednarz Minas Gerais State Research Institute (EPAMIG) Fazenda Experimental de Montes Claros Chacara Recanto dos Aracas MontesClaros Minas Gerais ZIP (CEP) : 39.404-128 Brazil Department of Plant and Soil Science Texas Tech University Lubbock Texas United States/Texas A&M AgriLife Texas 79409United States United States/Department of Plant and Soil Science Texas Tech University Bayer Cropscience U.S. 62 Idalou Texas 12108United States

Improving cotton irrigation management practices in West Texas is important for increasing farmers＇ profits and for sustainability of the Ogallala aquifer. The objective of this work was to evaluate the effects in field controlled episodic drought conditions on cotton gas exchange. Irrigated cotton was subjected to water stress at different timings. Irrigation was interrupted at the squaring stage, early flowering stage, from three weeks at peak bloom, and from peak bloom to the crop termination. These episodic drought treatments were compared with cotton fully irrigated throughout the whole season. From 2010 to 2012, cotton cultivar FM9180 gas exchange was measured throughout the season using a LiCor-6400 portable photosynthesis system. In 2011 and 2012, measurements were also made on DP0935 cultivar. The cotton physiological parameters evaluated included photosynthesis, transpiration and temperature. From the several parameters evaluated, some relationships were presented. Episodic drought periods can affect leaf-level gas exchange and impact yield. Photosynthesis and yield were particularly sensitive to water deficit at early flowering. Despite an increase in leaf water use efficiency under water deficit, overall growth and yield were inhibited in all treatments with a stress component. Understanding the relative sensitivity at different growth stages can help with irrigation decisions when water resources are limited.

关键词： Cotton physiology Gossypium hirsutum L. water stress gas exchange photosynthesis.

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Proton-pump inhibitor use does not affect semen luality in subfertile men

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Asian Journal of Andrology 2018年第3期20卷 290-293页

作者： Sorena Keihani James R craig Chong Zhang Angela P Presson Jeremy B Myers william O Brant Kenneth I Aston Benjamin R Emery Timothy G Jenkins Douglas T Carrell James M Hotaling Division of Urology Department of Surgery University of Utah Salt Lake City Utah 84132 USA Division of Epidemiology Department of Internal Medicine University of Utah Salt Lake City Utah 84132 USA Andrology and IVF Laboratory Department of Surgery (Urology) University of Utah Salt Lake City Utah 84108 USA

Proton-pump inhibitors （PPIs） are among the most widely used drugs worldwide. PPI use has recently been linked to adverse changes in semen quality in healthy men; however, the effects of PPI use on semen parameters remain largely unknown specifically in cases with male factor infertility. We examined whether PPI use was associated with detrimental effects on semen parameters in a large population of subfertile men. We retrospectively reviewed data from 12 257 subfertile men who had visited our fertility clinic from 2003 to 2013. Patients who reported using any PPIs for 〉3 months before semen sample collection were included; 7698 subfertile men taking no medication served as controls. Data were gathered on patient age, medication use, and conventional semen parameters; patients taking any known spermatotoxic medication were excluded. Linear mixed-effect regression models were used to test the effect of PPI use on semen parameters adjusting for age. A total of 248 patients （258 samples） used PPIs for at least 3 months before semen collection. In regression models, PPI use （either as the only medication or when used in combination with other nonspermatotoxic medications） was not associated with statistically significant changes in semen parameters. To our knowledge, this is the largest study to compare PPI use with semen parameters in subfertile men. Using PPIs was not associated with detrimental effects on semen quality in this retrospective study.

关键词： infertility proton-pump inhibitors semen analysis sperm quality spermatozoa

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Achieving fish passage outcomes at irrigation infrastructure;a case study from the Lower Mekong Basin

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Aquaculture and Fisheries 2021年第2期6卷 113-124页

作者： Lee J.Baumgartner Chris Barlow Martin Mallen-Cooper craig Boys Tim Marsden Garry Thorncraft Oudom Phonekhampheng Douangkham Singhanouvong william Rice Michael Roy Lin Crase Bethany Cooper Institute for Land Water and SocietyCharles Sturt UniversityElizabeth Mitchell DriveAlburyNew South WalesAustralia Department of Primary Industries Port Stephens Fisheries CentrePrivate Bag 1Nelson BayNew South Wales2315Australia Australasian Fish Passage Services 27 Beachside PlaceShoal PointQLD4750Australia National University of Laos PO Box 10864Dongdok CampusVientianeLao Democratic People’s Republic Living Aquatic Resources Research Centre Phonsavang VillageSikhotabong DistrictVientianeLao Democratic People’s Republic United States Department of the Interior International Technical Assistance Program1849 C StreetNWWashington DC20240United States University of South Australia School of CommerceCity West CampusAdelaideSouth AustraliaAustralia

Irrigation infrastructure expansion threatens the diversity of freshwater fish *** infrastructure creates migration barriers which can block access to important nursery,feeding and spawning *** PDR is a landlocked country situated within the Lower Mekong River Basin where there is a substantial dependency on rice and fish for food,income and *** country is experiencing an unprecedented boom in irrigation infrastructure investment,with modernisation programs being implemented in every *** significant investment in infrastructure upgrades,and the potential impact on freshwater fish,little consideration has been given to fish passage *** 2008,we commenced a fish passage program in Lao *** intent of this case study is to outline the pivotal elements of the program of knowledge development and transfer,in the context of river connectivity and fisheries management in Lao *** also highlight challenges in international research in development and lessons learned.

关键词： Fish passage Tropical rivers Lower mekong basin Migration Fishway Lao PDR

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Lateral Magma Flow in Mafic Sill-complexes

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Acta Geologica Sinica(English Edition) 2016年第S1期90卷 4-5页

作者： craig Magee James D Muirhead Alex Karvelas Simon P Holford Christopher A-L Jackson Ian D.Bastow Nick Schofield Carl TE Stevenson Charlotte Mc Lean william Mc Carthy Olga Shtukert Basins Research Group Department of Earth Science and Engineering Imperial CollegeLondon Department of Geological Sciences University of Idaho Schlumberger Multiclient Schlumberger House Buckingham Gate Australian School of Petroleum University of Adelaide Geology & Petroleum Geology School of Geosciences University of Aberdeen School of Geography Earth & Environmental Sciences University of Birmingham School of Geographical and Earth Sciences University of Glasgow Department of Earth Sciences University of St Andrews

The structure of upper crustal magma plumbing systems controls the distribution of volcanism and influences tectonic *** the structure and volume of plumbing systems is,however,difficult because:(1)active

关键词： Lateral Magma Flow in Mafic Sill-complexes

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Submaximal oxygen uptake kinetics, functional mobility, and physical activity in older adults with heart failure and reduced ejection fraction

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Journal of Geriatric Cardiology 2016年第5期13卷 450-457页

作者： Scott L Hummel John Herald craig Alpert Kimberlee A Gretebeck Wendy S Champoux Donald R Dengel Peter V Vaitkevicius Neil B Alexander Department of lnternal Medicine University of Michigan Ann Arbor MI USA VA Ann Arbor Healthcare System Ann Arbor MI USA School of Nursing University of Wisconsin-Madison Madison WI USA william Beaumont School of Medicine Oakland University Royal Oak MI USA School of Kinesiology University of Minnesota Minneapolis MN USA Aspirus Health System Ontanagon ML USA

Background Submaximal oxygen uptake measures are more feasible and may better predict clinical cardiac outcomes than maximal tests in older adults with heart failure （HF）. We examined relationships between maximal oxygen uptake, submaximal oxygen kinetics, fianctional mobility, and physical activity in older adults with HF and reduced ejection fraction. Methods Older adults with HF and reduced ejection fraction （n = 25, age 75 ：i： 7 years） were compared to 25 healthy ageand gender-matched controls. Assessments included a maximal treadmill test for peak oxygen uptake （VO2p^ak）, oxygen uptake kinetics at onset of and on recovery from a submaximal treadmill test, functional mobility testing [Get Up and Go （GUG）, Comfortable Gait Speed （CGS）, Unipedal Stance （US）], and self-reported physical activity （PA）. Results Compared to controls, HF had worse performance on GUG, CGS, and US, greater delays in submaximal oxygen uptake kinetics, and lower PA. In controls, VO2peak was more strongly associated with functional mobility and PA than submaximal oxygen uptake kinetics. In HF patients, submaximal oxygen uptake kinetics were similarly associated with GUG and CGS as VO2peak, but weakly associated with PA. Conclusions Based on their mobility performance, older HF patients with reduced ejection fraction are at risk for adverse functional outcomes. In this population, submaximal oxygen uptake measures may be equivalent to VO2 peak in predicting functional mobility, and in addition to being more feasible, may provide better insight into how aerobic function relates to mobility in older adults with HF.

关键词： Aging Congestive heart failure Mobility Oxygen uptake The elderly

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Engineering your future an introduction to engineering

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2002年

作者： authors william C. Oakes Les L. Leone craig J. Gunn.

来源：畅想之星图书光盘版（南... 评论

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