检索结果-南通市图书馆

利用流变-红外光谱同步测量研究化学反应的新方法

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

利用流变-红外光谱同步测量研究化学反应的新方法

Biosorption of Cadmium Ions by Unmodified, Microwave and Ultrasound Modified Brewery and Pure Strain Yeast Biomass

第十届全国流变学学术会议

作者： cornelia küchenmeister Jint Nijman klaus Oldrp Jan-Phillip Plog 范永忠 Manfred Feustel Thermo Fisher Scientific Dieselstraβe 476227 KarlsruheGermany 赛默飞世尔科技(中国)有限公司

本文介绍了一种流变/红外光谱同步测量的独特新方法。这种Rheonaut的新单元可以配合Thermo Scientific哈克MARS流变仪平台,在测量过程中加入FTIR红外光谱仪同步测量。样品可以在采用锥/平板或板/板转子情况下测量流变性能,同时记录相关... 详细信息

本文介绍了一种流变/红外光谱同步测量的独特新方法。这种Rheonaut的新单元可以配合Thermo Scientific哈克MARS流变仪平台,在测量过程中加入FTIR红外光谱仪同步测量。样品可以在采用锥/平板或板/板转子情况下测量流变性能,同时记录相关红外光谱图。为验证这个新方法,本文描述了哈克MARS流变仪配合Rheonaut单元进行相关聚合和交联反应的研究。根据反应过程中具体的化学特性,材料中的反应基团逐步消耗和/或新的化学基团出现,可以更好地说明和验证流变性能变化的原因。

关键词：流变测量红外光谱联用技术动态流变行为微观结构化学反应聚合交联

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

American Journal of Analytical Chemistry 2013年第7期4卷 63-71页

作者： Boldizsár Nagy Szende Tonk Cerasella Indolean Andrada Maicaneanu cornelia Majdik Faculty of Chemistry and Chemical Engineering Babes-Bolyai UniversityCluj-NapocaRomania Faculty of Sciences and Arts Sapientia Hungarian University of TransylvaniaCluj-NapocaRomania

The present study investigates the biosorption of cadmium ions from aqueous solution onto unmodified, ultrasound and microwave treated cells of Saccharomyces cerevisiae. FTIR analysis was conducted to characterize the biosorbent. Equilibrium and kinetic studies of unmodified RBW (residual brewery waste) cell yeast and DSM 1333 (pure strain) were conducted by considering the effect of initial cadmium ions concentration. Results showed that the ultrasound and microwave treatments decrease the heavy metal uptake compared with the unmodified biomass. Langmuir and Freundlich isotherm models on both unmodified yeast cell types were used to analyze the equilibrium data. It was found that the Langmuir isotherm and pseudo-second-order kinetics models describe better the cadmium ions removal process.

关键词： Biosorption Heavy Metals Saccharomyces cerevisiae Cells Isotherm kinetics

Resolving the taxonomy of emerging zoonotic pathogens in the Trichophyton benhamiae complex

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Fungal Diversity 2020年第5期104卷 I0001-I0055页

作者： AdélaČmoková Miroslav kolařík Radim Dobiáš Lois L.Hoyer Helena Janouškovcová Rui kano Ivana kuklová Pavlína Lysková Lenka Machová Thomas Maier Naďa Mallátová Matěj Man karel Mencl Pietro Nenoff Andrea Peano Hana Prausová Dirk Stubbe Silke Uhrlaß TomášVětrovský cornelia Wiegand Vit Hubka Department of Botany Faculty of ScienceCharles UniversityPragueCzech Republic Laboratory of Fungal Genetics and Metabolism Institute of MicrobiologyCzech Academy of SciencesPragueCzech Republic Public Health Institute in Ostrava OstravaCzech Republic Department of Biomedical Sciences Institute of Microbiology and ImmunologyFaculty of MedicineUniversity of OstravaOstravaCzech Republic Department of Pathobiology University of Illinois at Urbana-ChampaignUrbanaILUSA Faculty of Medicine in Pilsen Biomedical CenterCharles UniversityPilsenCzech Republic Department of Veterinary Dermatology Nihon University College of Bioresource SciencesFujisawaJapan Department of Dermatology and Venereology First Faculty of MedicineGeneral University Hospital in PragueCharles University and General University Hospital in PraguePragueCzech Republic Public Health Institute inÚstíNad Labem PragueCzech Republic Microbiological Laboratory/R&D Bioanalytics Bruker Daltonik GmbHBremenGermany Laboratory of Medical Parasitology and Mycology HospitalČeskéBudějoviceČeskéBudějoviceCzech Republic Institute of Botany Czech Academy of SciencesPrůhoniceCzech Republic Pardubice Regional Hospital PardubiceCzech Republic Laboratory of Medical Microbiology MölbisGermany Department of Veterinary Sciences University of TurinTurinItaly Clinical Veterinary Laboratory Labvet PragueCzech Republic Mycology and Aerobiology Service SciensanoBrusselsBelgium Laboratory of Environmental Microbiology Institute of MicrobiologyCzech Academy of SciencesPragueCzech Republic Department of Dermatology University Hospital JenaJenaGermany

Species of the Trichophyton benhamiae complex are predominantly zoophilic pathogens with a worldwide *** pathogens have recently become important due to their epidemic spread in pets and pet *** genetic and phenotypic variability has been revealed in these emerging pathogens,but the species limits and host spectra have not been clearly *** this study,we used an approach combining phylogenetic analysis based on four loci,population-genetic data,phenotypic and physiological analysis,mating type gene characterization and ecological data to resolve the taxonomy of these *** approach supported the inclusion of nine taxa in the complex,including three new species and one new *** benhamiae *** ***.(“yellow phenotype”strains)is currently a major cause of zoonotic tinea corporis and capitis in Europe(mostly transmitted from guinea pigs).The isolates of the“white phenotype”do not form a monophyletic group and are segregated into three taxa,*** ***(mostly North America;dogs),*** ***.(mostly Europe;guinea pigs),and *** ***.(predominant in East Asia but also found in Europe;rabbits and guinea pigs).The new species *** *** proposed for the“African”race of *** introduction to new geographic areas and host jump followed by extinction of one mating type gene have played important roles in the evolution of these *** to considerable phenotypic similarity of many dermatophytes and phenomena such as incomplete lineage sorting or occasional hybridization and introgression,we demonstrate the need to follow polyphasic approach in species *** evolving and noncoding DNA regions showed significantly higher discriminatory power compared to conventional protein-coding *** options for species identification in practice based on molecular markers,phenotype and MALDI-TOF spectra are presented.A microsatellite typi

关键词： Epizootic fungal infections Microsatellite typing scheme Multigene phylogeny Population genetic structure Superficial skin infections Zoophilic dermatophytes

Immunomodulatory Activities of a Concentrated Fruit and Vegetable Juice Tested in a Randomized,Placebo-Controlled,Double-Blind Clinical Trial in Healthy Volunteers

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food and Nutrition Sciences 2014年第4期5卷 341-350页

作者： Manfred Schmolz Reinhard W.Marz Marco Schaudt cornelia Schaudt Carola Lauster EDI GmbH ReutlingenGermany SCIRM FürthGermany Technische Hochschule NurembergGermany analyze&realize GmbH BerlinGermany

22 healthy volunteers were included in a randomized, placebo-controlled pilot study in order to investigate immunomodulatory effects of a concentrated juice, containing the ingredients of a total of 80 different fruits, vegetables, herbs, mushrooms, oils, and others (Cellagon aurum?, “CA”). 11 subjects received the concentrated juice while 11 were allocated to the placebo group. Stimulated whole-blood cultures were used to assess any treatment-related changes in the response of leukocytes towards experimental immune cell activation. For each of the individuals, 5 cultures were performed either immediately before, during, or 3 days after termination of the 7 weeks treatment. Leukocyte activities were determined by measuring cytokine levels in the supernatants at the end of the 48 h of stimulation (induced by the addition of LPS + SE-B + anti-CD28 antibodies). Despite the relatively small number of volunteers, multiplexed cytokine assays revealed a typical T-cell signature of cytokines that were increased significantly in the course of CA treatment compared to placebo (GM-CSF, IFNγ, IL-4, IL-10, IL-17, TNFβ, all p 0.05). These preliminary results suggest that CA is able to support leukocyte activation, in particular that of T-lymphocytes.

关键词： Randomized Placebo-Controlled Clinical Trial Ex Vivo Cytokine Juice Concentrate

Xe对NO(X)微分截面和非弹性散射中的碰撞诱导旋转准直

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Chemical Physics 2020年第2期33卷 217-233,I0003,J0001-J0017页

作者： Mark Brouard Helen Chadwick Sean D.S.Gordon cornelia GHeid Balazs Hornung Bethan Nichols Jacek klos Pablo GJambrina FJavier Aoiz 英国牛津大学化学系牛津OX13TA 美国马里兰大学化学与生物化学系马里兰州20742 西班牙萨拉曼卡大学化学科学学院物理化学系萨拉曼卡西班牙康普顿斯大学化学学院物理化学系马德里28040 Department of Chemistry Swansea UniversitySingleton ParkSwanseaSA28PPUK OneSwitch Technologies Batiment CEPFL Innovation Park1015 LausanneSwitzerland intellisense.io 60 Station RoadCambridgeCB12JHUK 400 Vermont Ave Moss BeachCA 94038USA

本文对NO(X)-Xe碰撞系统在碰撞能量为519 cm^-1,测量了完全?-双峰分解的微分截面和碰撞引起的旋转准直力矩.同时结合初始量子态选择,使用六极杆的非均质电场,借助量子态分辨的测量,利用(1+1')共振增强的多光子电离和速度离子成像.结果显... 详细信息

本文对NO(X)-Xe碰撞系统在碰撞能量为519 cm^-1,测量了完全?-双峰分解的微分截面和碰撞引起的旋转准直力矩.同时结合初始量子态选择,使用六极杆的非均质电场,借助量子态分辨的测量,利用(1+1')共振增强的多光子电离和速度离子成像.结果显示,微分截面以及偏振相关的微分截面均显示与从头算势能面上进行的量子力学散射计算[*** ***.137,014312(2012)]一致.通过与准经典轨迹、硬壳势能的量子力学散射以及运动近端模型的比较,评估了势能对所测微分截面和碰撞引起的旋转准直力矩的影响.

关键词：化学物理反应动力学非弹性散射

Patterns of Medication Use among Romanian Nursing Home Residents

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Pharmacology & Pharmacy 2014年第6期5卷 560-569页

作者： Daniela P. Primejdie Marius T. Bojita cornelia Revnic Adina Popa Faculty of Pharmacy “Iuliu Hatieganu” University of Medicine and Pharmacy Cluj-Napoca Romania

Background: the elderly are frequently exposed to drug-related problems and their consequences. Information relating to the appropriateness of the medication used by Romanian elderly is scarce. Objective: to identify the main potential inappropriate prescribing (PIP) instances in a sample of Romanian elderly nursing-home residents, concerning prevalence and subtypes. Methodology: the residents’ medical data were reviewed by a clinical pharmacist considering published geriatric pharmacotherapy recommendations, including four published PIP evaluation tools (the Beers criteria, STOPP-START tools, the PRISCUS list). Results: 91 residents were evaluated;mean age (mean ± SD) was 80.77 ± 6.82 (years), 28 (31%) were ≥85 years old and 58 (64%) had dementia. The median number of diagnoses was 6 (range 2 - 11) and the mean number (±SD) of daily medications was 8.26 (±3.52). An estimated mean (±SD) of 2 (±1.41) PIP per resident was identified, with 117 misuse-PIP (46.24%), 60 underuse-PIP (23.72%), 41 lack of monitoring-PIP (16.21%) and 35 overuse-PIP (13.83%). The most frequent PIP subtypes were the use of nonsteroidal anti-inflammatory drugs as chronic analgesic treatment in osteoarthritis (29.67%), underuse of fall prevention (100%) and analgesic therapies (23.08%), overuse of nootropic medications (26.98%) and lack of annual creatinine assessment (30.77%). Conclusion: a more geriatric-oriented care seemed to be necessary, but larger studies are needed to confirm these findings.

关键词： Potential Inappropriate Prescribing Drug-Related Problems Elderly Pharmacist Nursing Home

New advances in targeted gastric cancer treatment

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2016年第30期22卷 6776-6799页

作者： Daniela cornelia Lazar Sorina Taban Marioara Cornianu Alexandra Faur Adrian Goldis Department of Gastroenterology and Hepatology University of Medicine and Pharmacy 'Victor Babes' 300041 Timisoara Timis County Romania Department of Pathology University of Medicine and Pharmacy 'Victor Babes' 300041 Timisoara Timis County Romania

Despite a decrease in incidence over past decades,gastric cancer remains a major global health problem. In the more recent period, survival has shown only minor improvement, despite significant advances in diagnostic techniques, surgical and chemotherapeutic approaches, the development of novel therapeutic agents and treatment by multidisciplinary teams. Because multiple genetic mutations, epigenetic alterations, and aberrant molecular signalling pathways are involved in the development of gastric cancers, recent research has attempted to determine the molecular heterogeneity responsible for the processes of carcinogenesis, spread and metastasis. Currently, some novel agents targeting a part of these dysfunctional molecular signalling pathways have already been integrated into the standard treatment of gastric cancer, whereas others remain in phases of investigation within clinical trials. It is essential to identify the unique molecular patterns of tumours and specific biomarkers to develop treatments targeted to the individual tumour behaviour. This review analyses the global impact of gastric cancer, as well as the role of Helicobacter pylori infection and the efficacy of bacterial eradication in preventing gastric cancer development. Furthermore, the paper discusses the currently available targeted treatments and future directions of research using promising novel classes of molecular agents for advanced tumours.

关键词： Gastric cancer Helicobacter pylori infection Chemotherapy Targeted therapy Clinical trials New treat

Refining bioreactor design using autoclavable glass bonding

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advances in Bioscience and Biotechnology 2011年第4期2卷 233-243页

作者： cornelia Bahr Elisabeth Stammen Sarah Zahlten Stefan Bohm klaus Dilger Jochen Büchs AVT-Biochemical Engineering RWTH Aachen UniversityAachenGermany Institute of Joining and Welding Technische Universitat BraunschweigBraunschweigGermany Institute of Production Technology and Logistics Kassel UniversityKasselGermany

Selecting the right design of bioreactors is crucial for guaranteeing the reproducibility of bioprocesses. Up to now, conventionally designed bioreactors consist typically of melted or clamped joints. Since melting of borosilicate glass leads to large deformed areas along the joint, the desired geometric reproducibility is not ensured. Moreover, clamping complicates and greatly restricts the bioreactor design. Bonding, however, is advantageous in that it does not alter the material joined and it is easy to use. Furthermore, it has been recently shown that specially developed glass bonding techniques withstand multiple autoclaving cycles. The current research investigated practice-relevant parameters influencing the lifespan of epoxy-or (urethane) acrylate-bonded glass bioreactors. Hereby, the influence of cleaning and sensitivity to fermentation compounds (ethanol and acetic acid) was quantified using glass-glass and glass-stainless steel specimens. Whereas cleaning did not adversely affect the durability of glass bonds, high concentrations of the fermentation compounds ethanol and acetic acid resulted in accelerated corrosion and subsequent bond failure. Moreover, no effect of eight different epoxy and (urethane) acrylate adhesives was observed on selected model organisms Escherichia coli k12 and Hansenula polymorpha wild type. Another objective of this study was to refine the design of two small-scale bioreactors (ca. 250 mL) by replacing clamps and melted joints by adhesive joints. It was found that the bonded bioreactors yielded a higher geometric reproducibility than that of conventional melted or clamped ones. In conclusion, bonded glass joints greatly enhance the geometric reproducibility of bioreactors and, in turn, the reproducibility of bioprocesses. As glass bonding is easy to handle, it opens up new opportunities to design bioreactors that had been previously too expensive and complicated.

关键词： Bioreactor Durability Borosilicate Glass Stainless Steel 1.4301 Epoxy Adhesive Acrylate Adhesive

A Comparative Testing of <i>Cucumber mosaic virus</i>(CMV)-Based Constructs to Generate Virus Resistant Plants

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

American Journal of Plant Sciences 2012年第4期3卷 461-472页

作者： Xinqiu Tan Deyong Zhang Charlotte Wintgens Peter Willingmann Günter Adam cornelia Heinze Biocentre klein-Flottbek and Botanical Garden University of Hamburg Ham-burg Germany Hunan Plant Protection Institute Changsha China

Among the viruses Cucumber mosaic virus (CMV) has been rated worldwide as one of the five most important viruses infecting vegetable species. CMV is a tripartite virus with high sequence variability, classified into three subgroups with 80% to 97% identical nucleotides in their coat protein. Due to the absence of natural resistance CMV is the plant virus with longest history in genetic engineering using pathogen induced approaches. However, the transformation and regeneration for some very important crops like chili is difficult. Therefore it will be an advantage to screen in model plants for gene constructs which might be independent of the target of final transformation and other parameters having an influence on the efficiency of a biotechnological approach. In our study we compared the resistance for all combinations of five different antiviral constructs, two different transformation vectors and two model host plants. From these approaches we identified the most effective construct which might also be applicable to transform eventually chili plants.

关键词： Cucumber mosaic virus Transgenic Plant Resistance Comparison