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La vie estudiantine en Belgique

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法语学习 2014年第2期 60-62页

作者： corinne Bricmaan 北京外国语大学

La grande aventure commence:l'écolier devenuétudiant entrel'universitéou dans une grandeé***établissement d'enseignement choisi,il doit maintenant trouver un *** résidences universitaires offrent des chambres ... 详细信息

关键词： La vie estudiantine en Belgique

Dix belgicismes fréquents

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法语学习 2011年第4期 59-61页

作者： corinne Bricmaan 北京外国语大学

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Tintin

法语学习 2011年第6期 59-61页

作者： corinne Bricmaan 北京外国语大学

Tintin est un personnage de fiction créé en 1929 par le dessinateur belge Hergé(pseudonyme de Georges Remi),dans la bande dessinée Tintin au pays des *** jeune reporter est

关键词：法语学习法语美文法语阅读国家

The role of RAD9 in tumorigenesis

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Journal of Molecular Cell Biology 2011年第1期3卷 39-43页

作者： Howard B.Lieberman Joshua D.Bernstock Constantinos G.Broustas Kevin M.Hopkins corinne Leloup Aiping Zhu Center for Radiological Research Columbia University College of Physicians and Surgeons630 W.168th St.New YorkNY 10032USA Department of Environmental Health Sciences Mailman School of Public Health722 W.168th St.New YorkNY 10032USA

RAD9 regulates multiple cellular processes that influence genomic integrity,and for at least some of its functions the protein acts as part of a heterotrimeric complex bound to HUS1 and RAD1 ***9 participates in DNA repair,including base excision repair,homologous recombination repair and mismatch repair,multiple cell cycle phase checkpoints and *** addition,functions including the transactivation of downstream target genes,immunoglobulin class switch recombination,as well as 3′–5′exonuclease activity have been *** RAD9 expression has been linked to breast,lung,thyroid,skin and prostate tumorigenesis,and a cause–effect relationship has been demonstrated for the latter ***,human RAD9 overproduction correlates with prostate cancer whereas deletion of Mrad9,the corresponding mouse gene,in keratinocytes leads to skin *** results reveal that RAD9 protein can function as an oncogene or tumor suppressor,and aberrantly high or low levels can have deleterious health *** is not clear which of the many functions of RAD9 is critical for carcinogenesis,but several alternatives are considered herein and implications for the development of novel cancer therapies based on these findings are examined.

关键词： RAD9 tumor suppressor oncogene tumorigenesis cell cycle checkpoints DNA repair

La condition de la femme en Belgique (de 1830 à nos jours)

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法语学习 2013年第2期 59-62页

作者： corinne Bricmaan 北京外国语大学

L’histoire des relations entre les hommes et les femmes forme un savoir indispensable pour comprendre la place que chacun et chacune occupe dans la société actuelle. Connatre l’histoire des idées sur la féminité et la masculinité est ainsi fondamental pour déconstruire certaines idées reues sur les r?les sexués et pour lutter contre les discriminations, dont certaines sont encore

关键词：法语学习学习方法阅读知识阅读材料

Complete remission of gastric Burkitt's lymphoma after eradication of Helicobacter pylori

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World Journal of Gastroenterology 2009年第45期15卷 5746-5750页

作者： Isabelle Baumgaertner Christiane Copie-Bergman Michael Levy corinne Haioun Antoine Charachon Maryse Baia Iradj Sobhani Jean-Charles Delchier Department of Gastroenterology AP-HP Henri Mondor Hospital Paris 12 University 51 avenue du maréchal de Lattre de Tassigny Créteil 94000 France Department of Pathology AP-HP Henri Mondor Hospital Paris 12 University 51 avenue du maréchal de Lattre de Tassigny Créteil 94000 France Department of Hematology AP-HP Henri Mondor Hospital Paris 12 University 51 avenue du maréchal de Lattre de Tassigny Créteil 94000 France

Burkitt＇s lymphoma is a highly aggressive non-Hodgkin lymphoma, often presenting in extra-nodal sites. It generally has a poor spontaneous outcome and needs aggressive treatment with systemic and intrathecal chemotherapy. Occurrence at the gastric site is rare. We report the case of a 39-year old woman who presented with a prominent ulcerated lesion of the antrum corresponding histologically to a Burkitt＇s lymphoma associated with He/icobacter py/ori （H pylori） infection. Interphase fluorescence in situ hybridization （FISH） demonstrated c-MYC gene rearrangement in tumour cells without BCL2 or BCL6 gene translocations. Ulcer healing and tumour regression with a complete histological response were obtained 8 wk after Hpylori eradication. In spite of this complete remission, taking into account the high risk of recurrence, the patient received systemic and intrathecal chemotherapy. Two years later, the patient remained in complete remission. This is the first report of a gastric Burkitt＇s lymphoma responding to Hpylori eradication. These findings raise the question of the potential role of H pylori in the pathogenesis of some gastric Burkitt＇s lymphomas, and show the importance of searching for and eradicating the bacteria in combination with conventional chemotherapy regimens.

关键词： Burkitt's lymphoma Gastric lymphoma Helicobacter pylori Therapy

NTR/NRX Define a New Thioredoxin System in the Nucleus of Arabidopsis thaliana Cells

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Molecular Plant 2014年第1期7卷 30-44页

作者： corinne Marchal Valerie Delorme-Hinoux Laetitia Bariat Wafi Siala Christophe Belin Julio Saez-Vasquez Christophe Riondet Jean-Philippe Reichheld Universite Perpignan Via Domitia CNRS Laboratoire Genome et Developpement des Plantes UMR 5096 58 Avenue Paul Alduy-Bat T F-66860 Perpignan France Pharmacologie cellulaire et moleculaire Louvain Drug Research Institute Universite catholique de Louvain Brussels Belgium

Thioredoxins （TRX） are key components of cellular redox balance, regulating many target proteins through thiol/disulfide exchange reactions. In higher plants, TRX constitute a complex multigenic family whose members have been found in almost all cellular compartments. Although chloroplastic and cytosolic TRX systems have been largely studied, the presence of a nuclear TRX system has been elusive for a long time. Nucleoredoxins （NRX） are potential nuclear TRX found in most eukaryotic organisms. In contrast to mammals, which harbor a unique NRX, angiosperms gen- erally possess multiple NRX organized in three subfamilies. Here, we show thatArabidopsis thaliana has two NRXgenes （AtNRX1 and AtNRX2）, respectively, belonging to subgroups I and III. While NRX1 harbors typical TRX active sites （WCG/ PPC）, NRX2 has atypical active sites （WCRPC and WCPPF）. Nevertheless, both NRXl and NRX2 have disulfide reduction capacities, although NRX1 alone can be reduced by the thioredoxin reductase NTRA. We also show that both NRX1 and NRX2 have a dual nuclear/cytosolic localization. Interestingly, we found that NTRA, previously identified as a cytosolic protein, is also partially localized in the nucleus, suggesting that a complete TRX system is functional in the nucleus. We show that NRX1 is mainly found as a dimer in vivo. nrxl and nrx2 knockout mutant plants exhibit no phenotypic perturbations under standard growth conditions. However, the nrxl mutant shows a reduced pollen fertility phenotype, suggesting a specific role of NRX1 at the haploid phase.

关键词： thioredoxin nucleoredoxin nucleus Arabidopsis.

TEACHING SUSTAINABILITY IN BUILDING DESIGN AND ENGINEERING

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Journal of Green Building 2007年第1期2卷 175-195页

作者： David R.Riley Amy V.Grommes corinne E.Thatcher American Indian Housing Initiative(AIHI) Partnership for Achieving Construction Excellence(PACE) Pennsylvania State University Center for Sustainability(CfS) Pennsylvania State University Department of Architectural Engineering Pennsylvania State UniversityUniversity ParkPA 16802 Housing and Community Development Planning and Development DepartmentCity of Portland.389 Congress StreetRoom 308PortlandME 04101 104 Engineering Unit A Pennsylvania State UniversityUniversity ParkPA 16802

Engineers and building designers make decisions that have critical impacts on the environment and society,making sensitivity to environmental and social concerns a must in the building *** pedagogical research has been conducted to develop and assess techniques for integrating sustainability into building design and engineering *** paper describes an undergraduate course geared toward instilling concepts of sustainability in students of building-related disciplines and presents the findings of a case study and literature review conducted to identify the key features that made the course *** features are outlined in the form of an easy-to-use Sustainability in Higher Education Assessment Rubric(SHEAR)that faculty members can consult to shape effective programs and courses of their own to teach concepts of sustainability to their *** examples of this application are included,and recommendations for advancements in sustainability education are provided.

关键词： sustainability education engineering education environmental education service learning

NitroMAC：An instrument for the measurement of HONO and intercomparison with a long-path absorption photometer

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Journal of Environmental Sciences 2016年第2期28卷 105-113页

作者： Charbel Afif corinne Jambert Vincent Michoud Aurélie Colomb Gregory Eyglunent Agnès Borbon Véronique Daele Jean-Francois Doussin Pascal Perros Emissions Measurements and Modeling of the Atmosphere Laboratory EGFEM Unit Center for Analysis and Research Faculty of SciencesSaint Joseph University Beirut Lebanon Laboratoire Interuniversitaire des Systemes Atmospheriques (LISA) UMR7583 CNRS Universite Paris-Est-Creteil (UPEC) et Universite Paris Diderot (UPD) Institut Pierre Simon Laplace (IPSL) Creteil France Institut de Combustion Aerothermique Reactivite et Environnement CNRS Orleans France

Nitro MAC（French acronym for continuous atmospheric measurements of nitrogenous compounds） is an instrument which has been developed for the semi-continuous measurement of atmospheric nitrous acid（HONO）. This instrument relies on wet chemical sampling and detection using high performance liquid chromatography（HPLC）-visible absorption at540 nm. Sampling proceeds by dissolution of gaseous HONO in a phosphate buffer solution followed by derivatization with sulfanilamide/N-（1-naphthyl）-ethylenediamine. The performance of this instrument was found to be as follows： a detection limit of around 3 ppt with measurement uncertainty of 10% over an analysis time of 10 min. Intercomparison was made between the instrument and a long-path absorption photometer（LOPAP） during two experiments in different environments. First, air was sampled in a smog chamber with concentrations up to 18 ppb of nitrous acid. Nitro MAC and LOPAP measurements showed very good agreement. Then, in a second experiment, ambient air with HONO concentrations below250 ppt was sampled. While Nitro MAC showed its capability of measuring HONO in moderate and highly polluted environments, the intercomparison results in ambient air highlighted that corrections must be made for minor interferences when low concentrations are measured.

关键词： Atmospheric measurements Nitrous acid Sulfanilamide/N-(1-naphthyl)-ethylenediamine Long-path absorption photometer French acronym for continuous atmospheric measurements of nitrogenous compounds(NitroMAC)