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城市环境设计 2011年第7期 213-221页

作者： Carl Greaves coralie Huon Agata Borecka Julien Mirada Luca de Gaetano Anne Paillard Julien Loiseau Claude Ballini Taeho Kim Duncan Geddes Calvin Chua Kai Ong 王夏璐 rare建筑事务所天津大学建筑学院

市政厅酒店位于伦敦Burgeoning East End中心的旧Bethnal Green市政厅,是一家新的豪华酒店,拥有98间豪华客房、餐厅和酒吧,该项目于2010年11月完工包含对原建筑加建的顶层和侧翼以及对现存二级保护建筑的修复。这座建筑最初于1910年建于... 详细信息

市政厅酒店位于伦敦Burgeoning East End中心的旧Bethnal Green市政厅,是一家新的豪华酒店,拥有98间豪华客房、餐厅和酒吧,该项目于2010年11月完工包含对原建筑加建的顶层和侧翼以及对现存二级保护建筑的修复。这座建筑最初于1910年建于Cambridge Heath路,1937年扩建延伸至爱国者广场,那里也是新的酒店入口。后来这座7500m2的建筑成为了市政厅,但经历过数次翻新之后于1993年闲置下来。之后那里成为了放映电影和电视的场所,直到2007年被新加坡酒店投资者Peng Loh买了下来。业主在购买旧建筑之前进行了咨询,并决定在购买后立刻进行改建。rare建筑事务所的建筑师Michel da Costa Goncalves和Nathalie Rozencwajg接受了委托,对原建筑进行了改

关键词：市政厅 Bethnal Green 建筑师美术家酒店天津大学建筑学院客房平面图图(数学) 伦敦

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Cancer Occurrence and Associated Factors to Malignancy in BIRADS-3 Lesions in Yaoundé: The Need to Be More Proactive for Patients above 40, Non-Compliant with Imaging Follow-Up and Presenting with Nipple Discharge

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Open Journal of Medical Imaging 2023年第4期13卷 127-135页

作者： Joseph-Francis Nwatsock Ambroise Merci Seme-Engoumou coralie Reine Bertine Mendouga-Menye Etienne Atenguena-Okobalemba Lionel Tabola Boniface Moifo Department of Medical Imaging and Radiation Oncology Faculty of Medicine and Biomedical Sciences University of Yaoundé I Yaoundé Cameroon Department of Morphological Sciences and Pathology Faculty of Medicine and Biomedical Sciences University of Yaoundé I Yaoundé Cameroon Oncology Service Yaoundé General Hospital Yaoundé Cameroon

Background and objectives: Breast Imaging Reporting and Data System in Category 3 (BIRADS-3) includes probably benign lesions which need a short-term imaging follow-up. However, in our context, the lesions graded BIRADS-3 remain insufficiently evaluated. We therefore conducted this study to assess the cancer occurrence and associated factors in BIRADS-3 lesions during the follow-up in order to propose an adaptation of the management for lesions in this category in our setting. Patients and methods: A retrospective longitudinal study of patients with lesions initially classified as BIRADS-3 and who realised each at least one additional imaging check-up between January 2014 and December 2022 in five Yaoundé hospitals. All clinical and imaging data were analysed using SPSS® 21.0 software with a significant p-value Results: Patients were aged 13 to 73 (33.0 ± 13.4) years, with a history of breast mass (315 cases;79.7%), breast pain (25 patients;6.3%), nipple discharge (20 patients;5.1%) or past family history of breast cancer (25 cases;6.3%). The most common baseline abnormalities were mammogram opacities (64.8%) and microcalcifications (48.6%), whereas initial breast ultrasound showed solid masses (77.0%) and cystic lesions (11.1%). Compliance with imaging appointment periods was low with only 23.9% of all patients performing an imaging control at the scheduled moment. During the follow-up, 115 patients (29.1%) were upgraded to BIRADS-4 and histology performed revealed 43 cancers (10.9% of overall initial BIRADS-3 sample). The presence of malignancies was associated to age above 40 years (p = 0.0001) and to the presence of nipple discharge (p = 0.0375). Conclusion: The frequency of malignancies among initial BIRADS-3 lesions in our series is higher than that described in the guidelines. This study highlights the need to be more proactive in the management of BIRADS-3 lesions in our setting as the compliance with follow-up is low. So, biopsy should be conside

关键词： BIRADS-3 Cancer Occurrence Associated Factors to Malignancy Imaging Follow-Up Yaoundé

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60个新观点带你另眼看世界

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新发现 2020年第9期 24-66页

作者： Marie Atteia Kheira Bettayeb Coline Buanic Thomas Cavaillé-Fol Anne Debroise Olivier Donnars Stéphane Fay Lise Gougis coralie Hancok Román Ikonicoff Hugo Leroux Vincent Nouyrigat Alexandra Pihen Benoît Rey Yves Sciama Jean Baptiste Veyrieras 王隽(编译) 缪伶超(编译) 不详

它们中既有仍处于研究阶段的假设,也有尚未察觉的关联,还有已存在事实支撑但还未进行论证的主张……毕竟从灵光一现到范式形成的过程非常漫长;观点的建立与科研工作的开花结果都需要时间。植物会说话吗?雨水会引发火山喷发吗?

关键词：火山喷发科研工作另眼看开花结果观点

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Volumetric modulated arc radiotherapy for limited osteosclerotic myeloma

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World Journal of Radiology 2013年第4期5卷 173-177页

作者： Aurélie Robles Antonin Levy coralie Moncharmont Lamine Farid Jean-Baptiste Guy Nadia Malkoun Lysian Cartier Cyrus Chargari Isabelle Guichard Jean-Noёl Talabard Guy de Laroche Nicolas Magné Department of Radiotherapy Institut de Cancérologie de la Loire Department of Radiation Oncology Institut Gustave Roussy Université Paris XI Department of Radiation Oncology Hpital d'Instruction des Armées du Val-de-Grace Department of Internal Medicine CHU Saint Etienne

AIM:To assess the feasibility of volumetric intensity-modulated arc radiotherapy (VMAT) in patients with limited polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes syndrome. METHODS:A 70-year-old male with histologically confirmed osteosclerotic myeloma was treated in our department in July 2010 with VMAT. Fourty-six Gray in 23 fractions were given on three bone lesions. Doses delivered to target volume and critical organs were compared with a tridimensional conformal radiotherapy (3D-RT) plan. Treatment was well tolerated without any side ***:VMAT improved dose homogeneity within the target volume, as compared to 3D-RT (standard deviations:2.9 Gy and 1.6 Gy for 3D and VMAT, respectively). VMAT resulted in a better sparing of critical organs. Dose delivered to 20% of organ volume (D20) was reduced from 22 Gy (3D-RT) to 15 Gy (VMAT) for small bowel, from 24 Gy (3D-RT) to 17 Gy (VMAT) for bladder and from 47 Gy (3D-RT) to 3 Gy (VMAT) for spinal cord. Volumes of critical organs that received at least 20 Gy (V20) were decreased by the use of VMAT, as compared to 3D-RT (V20 bladder:10% vs 99%; V20 small bowel:6% vs 21%). One year after treatment completion, no tumor progression has been reported. CONCLUSION:VMAT improved dose distribution as compared to 3D-RT for limited osteosclerotic myeloma, with better saving of critical organs.

关键词： Volumetric intensity-modulated arc radiotherapy Conformal radiotherapy Critical organs Osteosclerotic myeloma Polyneuropathy organomegaly endocrinopathy monoclonal gammopathy and skin change syndrome

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