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国外医学（心血管疾病分册） 1990年第6期17卷 337-339页

作者： cooley da 周珉

本文报告得克萨斯心脏病研究所外科治疗感染性心内膜灸的经验。早期手术治疗的良好效果。重点讨论了外科手术的指证、时机、人造代用品的选择和术后并发症等问题。

关键词：感染性心内膜炎手术

心脏替代术:美国德萨斯心脏研究院对心脏移植和全人工心脏的经验

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国外医学.心血管疾病分册 1986年第1期 40-42页

作者： cooley da 江邦裕

十四年来,心脏移植有了重大的变化,手术技术和排异及感染的诊断及治疗均有明显的进展。但迄今仍有一个缺点,就是还不能紧急地应用于心脏手术后双心室衰竭的病人。两例采用了分期心脏移植术,其中第一期植入人工心脏,以弥补这个缺点。本... 详细信息

十四年来,心脏移植有了重大的变化,手术技术和排异及感染的诊断及治疗均有明显的进展。但迄今仍有一个缺点,就是还不能紧急地应用于心脏手术后双心室衰竭的病人。两例采用了分期心脏移植术,其中第一期植入人工心脏,以弥补这个缺点。本文是作者对心脏替代术的经验总结。

关键词：心脏移植植入术供心年作排异心脏心脏移植术研究院萨斯

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腹主动脉瘤

国际心血管病杂志 1985年第4期31卷 224-225页

作者： cooley da Carmichael MJ 杨西铭

应用手术切除腹主动脉瘤并行血管移植术已有30多年的历史。早在1953年就有报道7例腹主动脉瘤切除术和同种血管移植的病人,6例生存。嗣后,切除手术不断改进并广泛用于腹主动脉瘤的治疗,人造血管的应用可能是最主要的进展。很多作者将注... 详细信息

应用手术切除腹主动脉瘤并行血管移植术已有30多年的历史。早在1953年就有报道7例腹主动脉瘤切除术和同种血管移植的病人,6例生存。嗣后,切除手术不断改进并广泛用于腹主动脉瘤的治疗,人造血管的应用可能是最主要的进展。很多作者将注意力集中于切除手术的指证方面,提出动脉瘤究竟长至多大才放弃观察代之以手术治疗,新近认为直径超过6厘米的腹主动脉瘤随时可能破裂致死,应予手术。

关键词：腹主动脉瘤病人血管移植手术切除切除手术急症手术

Dietary modification in the treatment of schizophrenia spectrum disorders: A systematic review

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World Journal of Psychiatry 2020年第8期10卷 187-201页

作者： Monique Aucoin Laura LaChance Sam N Clouthier Kieran cooley Department of Research and Clinical Epidemiology Canadian College of Naturopathic MedicineToronto M2K 1E2Canada Department of Psychiatry McGill UniversityMontreal H3A 0G4Canada Centre for Addiction and Mental Health Toronto M6R 1A1Canada Department of Doctoral Acupuncture and Chinese Medicine Pacific College of Health ScienceSan DiegoCA 92108United States

BACKGROUND Schizophrenia spectrum disorders impact functioning,reduce quality of life and increase the risk of physical illness and premature *** intervention studies aimed at decreasing body weight have demonstrated efficacy in improving metabolic outcomes;however,few studies have explored the impact of interventions designed to modify diet on mental health *** To synthesize the existing experimental studies of adjunctive diet modification as an intervention in the treatment of psychotic disorders,analyze findings related to effectiveness and safety,highlight knowledge gaps and limitations,and set forward recommendations for future research *** An extensive a priori search strategy was developed and the databases Embase,Embase Classic,Ovid MEDLINE were *** and data extraction were completed in *** included in this analysis were experimental studies of an adjunctive dietary intervention(overall dietary pattern or education on dietary change)for treatment of schizophrenia spectrum *** restrictions were placed on control groups or *** studies were required to report a mental health *** Twenty-five clinical trials were identified,along with two additional protocols and two *** of the clinical trials reported improvement in one or more mental health domain including psychosis symptoms,cognition,and quality of life.A high level of heterogeneity was found with respect to patient population,intervention,and study *** of the studies included lifestyle or psychosocial components in addition to dietary *** nutrition advice provided to participants was poorly described overall and compliance was not *** studies that showed benefit tended to have a smaller sample size and were less likely to be randomized but were more likely to use a group delivery *** Further research assessing effectiveness and efficacy of clear

关键词： Nutrition Psychosis Schizophrenia Diet

Adventures of Huckleberry Finn

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Characterization of the interaction of nanobubble ultrasound contrast agents with human blood components

作者： Mark Twain edited by Thomas cooley.

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生物活性材料(英文) 2023年第1期19卷 642-652页

作者： Michaela B.cooley Eric C.Abenojar dana Wegierak Anirban Sen Gupta Michael C.Kolios Agata A.Exner Department of Biomedical Engineering Case Western Reserve UniversityClevelandOH44106United States Department of Radiology Case Western Reserve UniversityClevelandOH44106United States Department of Physics Ryerson UniversityTorontoOntarioM5B 2K3Canada Institute for Biomedical Engineering and Science Technology A Partnership Between Ryerson University and St.Michael’s HospitalTorontoOntarioM5B 1T8Canada

Nanoscale ultrasound contrast agents,or nanobubbles,are being explored in preclinical applications ranging from vascular and cardiac imaging to targeted drug delivery in *** sub-micron particles are approximately 10x smaller than clinically available *** allows them to effectively traverse compromised physiological barriers and circulate for extended periods of *** various aspects of nanobubble behavior have been previously examined,their behavior in human whole blood has not yet been ***,herein we examined,for the first time,the short and long-term effects of blood components on nanobubble acoustic *** observed differences in the kinetics of backscatter from nanobubble suspensions in whole blood compared to bubbles in phosphate buffered saline(PBS),plasma,or red blood cell solutions(RBCs).Specifically,after introducing nanobubbles to fresh human whole blood,signal enhancement,or the magnitude of nonlinear ultrasound signal,gradually increased by 22.8±13.1%throughout our experiment,with peak intensity reached within 145 *** contrast,nanobubbles in PBS had a stable signal with negligible change in intensity(􀀀1.7±3.2%)over 8 *** the same conditions,microbubbles made with the same lipid formulation showed a􀀀56.8±6.1%decrease in enhancement in whole *** confocal,fluorescent,and scanning electron microscopy analysis revealed attachment of the nanobubbles to the surface of RBCs,suggesting that direct interactions,or hitchhiking,of nanobubbles on RBCs in the presence of plasma may be a possible mechanism for the observed *** phenomenon could be key to extending nanobubble circulation time and has broad implications in drug delivery,where RBC interaction with nanoparticles could be exploited to improve delivery efficiency.

关键词： Nanobubbles Ultrasound contrast agents Red blood cells Hitchhiking Ultrasound Drug delivery

Taking the pulse of a plant:dynamic laser speckle analysis of plants

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红外与激光工程 2016年第9期45卷 7-18页

作者： Zhong Xu Wang Xuezhi cooley Nicola Farrell Peter Moran Bill Department of Infrastructure Engineering University of Melbourne School of Electrical and Computer Engineering Royal Melbourne Institute Technology Higher Education-Primary Industy NMIT and Melbourne PolytechnicNMIT Epping Campus Department of Electrical and Electronic Engineering University of Melbourne

Ideally, to achieve optimal production in agriculture, crop stress needs to be measured in real-time, and plant inputs managed in response. However, many important physiological responses like photosynthesis are difficult to measure, and current trade-offs between cost, robustness, and spatial measurement capacity of available plant sensors may prevent practical in-field application of most current sensing techniques. This paper investigates a novel application of laser speckle imaging of a plant leaf as a sensor with an aim, ultimately, to detect indicators of crop stress: changes to the dynamic properties of leaf topography on the scale of the wavelength of laser light. In our previous published work, an initial prototype of the laser speckle acquisition system specific for plant status measurements together with data processing algorithms were developed. In this paper, we report a new area based statistical method that improves robustness of the data processing against disturbances from various sources. Water and light responses of the laser speckle measurements from cabbage leaves taken by the developed apparatus are exhibited via growth chamber experiments. Experimental evidence indicates that the properties of the laser speckle patterns from a leaf are closely related to the physiological status of the leaf. This technology has the potential to be robust, cost effective, and relatively inexpensive to scale.

关键词：磁光阵列光存储融合存储

Adult dental epithelial stem cell-derived organoids deposit hydroxylapatite biomineral

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International Journal of Oral Science 2023年第4期15卷 676-690页

作者： Hyun-Yi Kim Victoria cooley Eun-Jung Kim Shujin Li Jong-Min Lee Dina Sheyfer Wenjun Liu Ophir D.Klein Derk Joester Han-Sung Jung NGeneS Inc. Ansan-siGyeonggi-doKorea Department of Materials Science and Engineering Northwestern UniversityEvanstonILUSA X-ray Science Division Advanced Photon SourceArgonne National LaboratoryLemontILUSA Division in Anatomy and Developmental Biology Department of Oral BiologyOral Science Research CenterBK21 FOUR ProjectYonsei University College of DentistrySeoulKorea Department of Orofacial Sciences and Program in Craniofacial Biology University of CaliforniaSan FranciscoCAUSA Department of Pediatrics Cedars-Sinai Guerin Children’sLos AngelesCAUSA

Ameloblasts are specialized cells derived from the dental epithelium that produce enamel,a hierarchically structured tissue comprised of highly elongated hydroxylapatite(OHAp)*** unique function of the epithelial cells synthesizing crystallites and assembling them in a mechanically robust structure is not fully elucidated yet,partly due to limitations with in vitro experimental ***,we demonstrate the ability to generate mineralizing dental epithelial organoids(DEOs)from adult dental epithelial stem cells(aDESCs)isolated from mouse incisor *** expressed ameloblast markers,could be maintained for more than five months(11 passages)in vitro in media containing modulators of Wnt,Egf,Bmp,Fgf and Notch signaling pathways,and were amenable to *** transplanted underneath murine kidney capsules,organoids produced OHAp crystallites similar in composition,size,and shape to mineralized dental tissues,including some enamel-like elongated *** are thus a powerful in vitro model to study mineralization process by dental epithelium,which can pave the way to understanding amelogenesis and developing regenerative therapy of enamel.

关键词： epithelium maintained specialized

Athletes Who Sparkle： Stereotypes in the Televised Coverage of the 2010 Olympic Figure Skating Events

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Journalism and Mass Communication 2013年第5期3卷 292-303页

作者： Amy H. Jones Skye C. cooley Department of Languages and Literature University of West Alabama Department of Communication Mississippi State University

A vast amount of research has been devoted to gender roles in mass media. Prior studies relating to gender roles in media coverage of sports have been typically centered on underrepresentation, negative stereotypical portrayals of female athletes, and iconic heroic portrayals of male athletes. However, few studies have examined media coverage of male participation in so-called ＂gender inappropriate＂ sports. This research seeks to fill a gap in literature by exploring gender cues presented in the televised coverage of male and female figure skating events in the 2010 Winter Olympic Games. The findings from this research indicate that male athletes who cross gender barriers to participate in a feminine sport are likely to receive gender-marked stereotypical televised coverage. Much of the significant findings indicate that male figure skaters were visually and verbally portrayed as more feminine than the female figure skaters. The study opens lines of research into how sports are portrayed and could potentially influence sport marketing, athlete endorsements, athlete wardrobe, and other decisions made by the media, athletes, and individuals working in the sport industry.

关键词： gender stereotypes athletes figure skating televised coverage

Laser controlled quantum electrodynamics

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Laser controlled quantum electrodynamics