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糖化血红蛋白评估合并重度肢体缺血糖尿病患者严重程度值得商榷(英文)

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临床麻醉学杂志 2011年第8期27卷 831-832页

作者：汉密尔顿.谢尼古拉斯.加奎罗戴维.奥康纳盖布里埃尔.鲁福兰克.维斯 Department of Anesthesiology Montefiore Med.Ctr./Albert Einstein Coll.of Med.BronxNew YorkUnited States

术前糖化血红蛋白(HbA1c)水平是合理判断患者近几个月血糖控制情况的重要指标,并被用于估计术前和术中胰岛素的需要量。严格的血糖控制应能减少手术并发症和改善预后。本研究回顾148例合并重度肢体缺血的糖尿病患者接受介入治疗的情况,... 详细信息

术前糖化血红蛋白(HbA1c)水平是合理判断患者近几个月血糖控制情况的重要指标,并被用于估计术前和术中胰岛素的需要量。严格的血糖控制应能减少手术并发症和改善预后。本研究回顾148例合并重度肢体缺血的糖尿病患者接受介入治疗的情况,分析HbA1c是否与合并重度肢体缺血的糖尿病患者病情的严重程度相关。结果提示,对合并重度肢体缺血的糖尿病患者,通过HbA1c判断血糖控制不能评价疾病的严重程度和是否需要再次介入治疗,糖尿病相关的其他因素影响外周血管疾病的发生,需要大型的前瞻性的临床试验来评估血糖控制在重度肢体缺血中的应用。后续研究还将关注何种麻醉方式适合合并肢体缺血的糖尿病患者。

关键词：重度肢体缺血糖化血红蛋白糖尿病患者评估外周血管疾病 HbA1c 血糖控制

未控制高血压患者进行家庭血压监测与药剂师管理后的心血管事件及费用

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中华高血压杂志 2020年第11期28卷 1018-1018页

作者：赵狄(摘译) 刘莉(审校) Margolis KL Dehmer SP Sperl-Hillen j O’connor Pj Asche SE Bergdall AR Green BB Nyboer RA Pawloski PA Trower NK Maciosek MV 不详

未控制高血压是心血管病的主要病因。在16家初级保健诊所进行的整群随机试验结果表明:12个月的远程家庭血压监测与药剂师管理可较常规治疗24个月降压幅度更大。该文报道心血管事件(非致死性心肌梗死、非致死性脑卒中、心力衰竭住院、冠... 详细信息

未控制高血压是心血管病的主要病因。在16家初级保健诊所进行的整群随机试验结果表明:12个月的远程家庭血压监测与药剂师管理可较常规治疗24个月降压幅度更大。该文报道心血管事件(非致死性心肌梗死、非致死性脑卒中、心力衰竭住院、冠状动脉再血管化及心血管病死亡)与随访5年的花费。在远程干预组(TI组,n=228),10例患者发生15次心血管事件(5次心肌梗死、4次脑卒中、5次心力衰竭、1次心血管病死亡)。

关键词：心血管事件降压幅度家庭血压监测心血管病心力衰竭心肌梗死高血压患者保健诊所

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儿科患者的门脉性肺动脉高压

世界核心医学期刊文摘（儿科学分册） 2005年第12期1卷 30-30页

作者： Condino A.A. Ivy D.D. O'connor j.A. 郭战宏 Pediatric Cardiology 1056 East 19th Avenue Denver CO 80218 United StatesDr.

To investigate the clinical presentation, manifestations, and response to therapy of portopulmonary hypertension (PPHTN) in pediatric patients. Study design: This study was a retrospective chart review describing the evaluation and course of 7 patients with PPHTN. Results: Causes of portal hypertension (HTN) included biliary atresia (3 cases), cavernous transformation of the portal vein (2 cases), and primary sclerosing cholangitis and cryptogenic cirrhosis (1 case each). The median interval from the diagnosis of portal HTN to PPHTN was 12.1 years. Four patients presented with a new heart murmur, 4 presented with syncope, and 3 presented with dyspnea. Although electrocardiograms (ECGs) and chest x-rays were normal in 3 and 2 patients, respectively, echocardiograms diagnosed pulmonary HTN in all 7 patients. Five patients had cardiac catheterizations; the average mean pulmonary artery pressure was 65 ± 20 mmHg. Response to therapy was variable, and 4 patients died. Postmortem lung tissue examination revealed plexiform lesions and pulmonary arteriopathy. Conclusions: Because symptoms are subtle and may be overlooked, pediatric patients with portal HTN who develop a new heart murmur, dyspnea, syncope, or who are being evaluated for liver transplantation require evaluation for PPHTN. ECG and chest x-ray are insensitive screens for PPHTN. An echocardiogram and cardiology evaluation is essential for the diagnosis.

关键词：儿科患者肺动脉高压脉性胆道闭锁心脏超声检查心脏杂音呼吸困难平均肺动脉压图表分析心导管检查

Cumulative radiation exposure from diagnostic imaging in intensive care unit patients

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World journal of Radiology 2016年第4期8卷 419-427页

作者： Fiachra Moloney Daniel Fama Maria Twomey Ruth O'Leary Conor Houlihane Kevin P Murphy Siobhan B O'Neill Owen j O'connor Dorothy Breen Michael M Maher Department of Radiology Cork University Hospital Department of Anesthesia Cork University Hospital

AIM:To quantify cumulative effective dose of intensive care unit(ICU)patients attributable to diagnostic ***:This was a prospective,interdisciplinary study conducted in the ICU of a large tertiary referral and level 1 trauma *** and clinical data including age,gender,date of ICU admission,primary reason for ICU admission,APACHE Ⅱ score,length of stay,number of days intubated,date of death or discharge,and re-admission data was collected on all patients admitted over a 1-year *** overall radiation exposure was quantified by the cumulative effective radiation dose(CED)in millisieverts(mS v)and calculated using reference effective doses published by the United Kingdom National Radiation Protection *** patients were selected for ***:A total of 2737 studies were performedin 421 *** total CED was 1704 m Sv with a median CED of 1.5 mS v(IQR 0.04-6.6 mS v).Total CED in pediatric patients was 74.6 mS v with a median CED of 0.07 mS v(IQR 0.01-4.7 mS v).Chest radiography was the most commonly performed examination accounting for 83% of all studies but only 2.7% of total *** tomography(CT)accounted for 16% of all studies performed and contributed 97% of total *** patients received a statistically significant higher dose [median CED 7.7 mS v(IQR 3.5-13.8 mS v)] than medical [median CED 1.4 m Sv(IQR 0.05-5.4 m Sv)] and surgical [median CED 1.6 mS v(IQR 0.04-7.5 mS v)] *** of stay in ICU [OR = 1.12(95%CI:1.079-1.157)] was identified as an independent predictor of receiving a CED greater than 15 mS ***:Trauma patients and patients with extended ICU admission times are at increased risk of higher *** should be minimized where feasible,especially in young patients.

关键词： Cumulative effective dose Pediatric patients Computed tomography Radiation dose Intensive care unit

CT在临床可疑耳硬化症评估中的诊断疗效和治疗影响

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国际医学放射学杂志 2017年第3期 359-359页

作者： C.Dudau F.Salim D.jiang S.E.j.connor 邓艳 Department of Neuroradiology King ’s College Hospital NHS Foundation Trust

摘要目的探讨CT在临床疑诊耳硬化症病人评估中的诊断疗效和对治疗的影响。方法回顾性分析接受CT扫描超过5年的临床可疑为耳硬化症的病人,CT诊断与后续手术治疗方式有关。对耳硬化症阳性的病例,判断有明显扩张的耳硬化症与听力测试的关... 详细信息

摘要目的探讨CT在临床疑诊耳硬化症病人评估中的诊断疗效和对治疗的影响。方法回顾性分析接受CT扫描超过5年的临床可疑为耳硬化症的病人,CT诊断与后续手术治疗方式有关。对耳硬化症阳性的病例,判断有明显扩张的耳硬化症与听力测试的关系、诊断与手术结果的关系。结果在CT显示的259例耳硬化症病人中,46%为阳性,49%阴性,5%无法判断。对于33%阴性诊断病人,CT诊断依据充分。每4个CT检查中就有一个实行了针对性外科手术。在41%的CT结果阳性、4%的CT结果阴性的病人中,CT结果

关键词：耳硬化症阳性耳疾病 CT 疗效

爱尔兰中西部沙眼衣原体在男性人群中的流行程度

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世界核心医学期刊文摘（皮肤病学分册） 2005年第3期1卷 33-33页

作者： Powell j. O’connor C. O’híarlaithe M. 阎小宁 Powell Department of MicrobiologyMid-Western Regional Hospital Doorodoyle Limerick City Ireland

Objectives: To estimate the prevalence of chlamydia infection in young men in the Mid-Western Health Board Region of Ireland, and to determine risk factors for its acquisition. Methods: Consecutive men attending orthopaedic clinics (OP D), and a university sports arena (UL) were recruited to a chlamydia prevalence study. All men aged 17- 35 who had been sexually active and had not passed urin e in the last hour were eligible. Information about chlamydia was given, informe d consent obtained, and a self administered questionnairewas completed. A first void urine (FVU) was collected and tested by ligase chain reaction (LCR). Result s: 82% (207/252) of men from OPD, and 60% (186/310) from UL participated. 6. 3% (13/207) from the OPD and 5.4% (10/186) from UL tested LCR positive, givi ng an overall prevalence of 5.9% (23/ 393). Proved risk factors for chlamydial positivity were: (1) more than one sexual partner in previous 6 months, (2) mor e than eight lifetime sexual partners, (3) current symptoms (dysuria or discharg e)- . No statistical significance was found for age, condom use, smoking, days since last sexual intercourse and previous GUM clinic attendance. No statistical ly significant difference to cost effective prevalence of 6% was shown. Conclu sions: A 5.9% prevalence of Chlamydia trachomatis was found which is cost effe ctive to screen and treat. Non-invasive screening of men in the community was possible. Numbers of sexual partners and current symptoms were significant risk factors. Since only 25% of men in this laboratory were diagnosed with chlamydi a outside the GUM clinic, compared with 59% of women, it is important that com munity screening of men is promoted.

关键词：沙眼衣原体男性人群流行程度检诊年轻男性性伴侣知情同意书整形外科链反应排尿困难

A Company Presents Itself to the World

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journal of Literature and Art Studies 2023年第10期13卷 803-811页

作者： Richard j.Alexander Vienna University of Business and Economics ViennaAustria

As we all know,environmental breakdown is rooted in capitalism’s quest for perpetual *** to O’connor(quoted in Büscher et al 2010/2013,p.3)the“environmental crisis has given liberal capitalist society a new lease on life.”He continues:“Now,through purporting to take in hand the saving of the environment,capitalism invents a new legitimation for itself:the sustainable and rational use of nature”.“Those who hold the power and they are not all heads of state,see themselves as saviours of the world,and offer the population the opportunity of becoming their clients”is how john Berger has referred to such cognitive *** discourse analysis and corpus linguistics are employed to scrutinize a powerful corporation’s *** company produces and distributes food *** story it presents to the world maintains that it protects animal welfare,the environment and people,among other things,in all its *** language it employs on its corporate websites will be subjected to close analysis.

关键词： agribusiness discourse analysis ecolinguistics greenwashing sustainability

非诺贝特治疗与2型糖尿病患者长期心血管病风险的关系

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中华高血压杂志 2017年第6期25卷 534-534页

作者：刘莉叶鹏 Elam MB Ginsberg HN Lovato LC Corson M Largay j Leiter LA Lopez C O'connor Pj Sweeney ME Weiss D Friedewald WT Buse jB Gerstein HC Probstfield j Grimm R Ismail-Beigi F Goff DC jr Fleg jL Rosenberg Y Byington RP ACCORDION study investigators

2型糖尿病患者心血管病风险高,部分原因在于高三酰甘油和低高密度脂蛋白胆固醇血症。而在他汀类药物治疗基础上,加强降低三酰甘油治疗,能否降低这种风险尚不清楚。该研究的目的是在使用他汀类药物治疗的2型糖尿病患者中,确定非诺贝特能... 详细信息

2型糖尿病患者心血管病风险高,部分原因在于高三酰甘油和低高密度脂蛋白胆固醇血症。而在他汀类药物治疗基础上,加强降低三酰甘油治疗,能否降低这种风险尚不清楚。该研究的目的是在使用他汀类药物治疗的2型糖尿病患者中,确定非诺贝特能否降低心血管病风险。

关键词： 2型糖尿病药物治疗心血管病非诺贝特风险患者高三酰甘油高密度脂蛋白

脊椎关节炎病人的跟腱成像:超声与增强前、后的常规以及短和超短回波时间MRI的比较

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国际医学放射学杂志 2011年第4期 401-401页

作者： R.j.Hodgson A.j.Grainger P.j.O'connor R.Evans L.Coates H.Marzo-Ortega 陈娇 Leeds Musculoskeletal Biomedical Research Centre University of Leeds

目的比较常规、超短回波时间MRI和超声评估脊椎关节炎病人跟腱病变的范围。方法应用MRI和超声研究25例脊椎关节炎并有跟腱症状的病人。静脉注射对比剂前后分别使用T1加权自旋回波、梯度回波和超短回波时间序列(TE选择0.07～16ms)来获得... 详细信息

目的比较常规、超短回波时间MRI和超声评估脊椎关节炎病人跟腱病变的范围。方法应用MRI和超声研究25例脊椎关节炎并有跟腱症状的病人。静脉注射对比剂前后分别使用T1加权自旋回波、梯度回波和超短回波时间序列(TE选择0.07～16ms)来获得跟腱的MR影像。同时也进行

关键词：脊柱关节炎跟腱 MRI 超声检查多普勒肌腱疾病