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rapid strep testing in children with recently treated streptococcal pharyngitis

Pediatric Investigation 2019年第1期3卷 27-30页

作者： Amin J.Barakat coni evans Monica Gill David Nelson Georgetown University Medical Center Washington DCUSA Northern Virginia Pediatric Associates Falls ChurchVAUSA Children’s Medical Associates of Northern Virginia AlexandriaVAUSA

Importance:The use of the rapid antigen-detection test(RADT)has become the standard of care in the early diagnosis of group A beta-hemolytic Streptococcus(GAS)*** has been expressed over increased false positives when the child had been treated recently for GAS pharyngitis,resulting in over use of ***:To determine if the false positive rate for RADT is increased in children recently treated for GAS ***:We conducted a prospective study to evaluate 300 children from a private practice with acute pharyngitis who were treated for GAS pharyngitis within the preceding 28 days(study group)compared to 306 children of comparable age who had not been previously treated(control group).RADT and throat culture were performed on all children presenting with signs and symptoms of acute *** false positive and false negative rates were determined and compared in both ***:The false positive rate of 11.5%(23/200)in the study group was significantly higher than the false positive rate of 0 in the control *** positives were more likely to occur in younger ***:These data would indicate that while RADT is reliable in most children,it can lead to over treatment in children who have been recently treated for *** children treated in the preceding 28 days for GAS pharyngitis,the presence of infection should be determined with a throat culture *** based on a positive RADT should be reserved for children not recently treated for GAS pharyngitis.

关键词： Group A beta-hemolytic Streptococcus rapid antigen-detection test GAS pharyngitis

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