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Quantitative characterization of granular size segregation:A critical review

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Particuology 2024年第12期95卷 166-177页

作者： cong Leng Chengfeng Sun Zhehan Liao jian xu College of Materials Science and Engineering Chongqing UniversityChongqing400044China

Granular size segregation is an inevitable phenomenon in both natural and industrial *** understand the underlying mechanisms and develop effective optimization strategies,it is essential to employ robust methodologies that can quantitatively characterize and evaluate size segregation behaviors in granular *** review critically examines a wide variety of state-of-the-art methodologies from recent studies to quantify granular size *** features of these methodologies are extracted and organized into a comprehensive *** key questions are thoroughly discussed:evaluation criteria for identical segregation states,sensitivity to sample size,the influence of sampling division pattern,and the capability of handling multiple-component ***,we provide an outlook on the future development of advanced and effective methodologies for granular size segregation characterization.

关键词： Granular system Size segregation Quantitative characterization Multi-scale framework

Clinicopathological differences between patients with schistosomal appendicitis and non schistosomal appendicitis:A retrospectively study of past ten years

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World Journal of Clinical Cases 2025年第2期13卷 24-32页

作者： Xiao-Yi Wang Yao Hao Zi-jian Wang Xiu-Liang xu jiang-Hua Yang Department of Infectious Diseases The First Affiliated of Wannan Medical CollegeWuhu 241001Anhui ProvinceChina

BACKGROUND Chronic schistosomiasis causes multiple organ and multiple system diseases,especially the digestive *** eggs are mainly deposited in the stomach,liver and colorectal,but a few eggs are deposited in the appendix and cause *** present,there are few studies on schistosomal *** To explore the differences in epidemiological,clinical and pathological characteristics between schistosomal appendicitis and non-schistosomal appendicitis over the past decade in order to assess the impact of schistosomiasis on *** The differences of general data,clinical data and laboratory examination data of patients with appendicitis from October 2013 to October 2023 were retrospectively *** patients were divided into two groups for *** were 136 patients in schistosomal appendicitis group and 5418 patients in non-schistosomal appendicitis *** Schistosomal appendicitis accounted for 2.45%of all patients with appendicitis,and the annual proportion in the past decade was 2.2%,2.9%,1.8%,1.9%,3.4%,3.1%,1.9%,1.6%,3%,2.6%,*** prevalence of schistosomal appendicitis was middle-aged and elderly males,with an average age of 61.73±15.335 *** main population of non-schistosomal appendicitis was middle-aged men,with an average age of 35.8±24.013 years(P<0.001).The distribution of pathological types of appendicitis was different between the two groups(P<0.001).The incidence of acute suppurative appendicitis in non-schistosomal appendicitis was higher than that in schistosomal appendicitis[odds ratio(OR)=0.504;95%confidence interval(CI):0.349-0.728;P<0.001].The proportion of acute attack of chronic appendicitis in schistosomal appendicitis was higher than that in non-schistosomal appendicitis(OR=2.614;95%CI:1.815-3.763;P<0.001).The proportion of schistosomal appendicitis patients complicated with colorectal cancer was higher than that of nonschistosomal appendicitis patients(OR=5.087;95%CI:1.427-

关键词： Schistosomal appendicitis Schistosomiasis Appendix Colorectal cancer Clinicopathological characteristics

Preimplantation genetic testing guidelines of International Society of Reproductive Genetics

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Reproductive and Developmental Medicine 2023年第1期7卷 3-11页

作者： Chen-Ming xu Si-Jia Lu Song-Chang Chen Jing-Lan Zhang cong-jian xu Yuan Gao Yi-Ping Shen Yun-Xia Cao Ling-Qian Wu Fan Jin Ge Lin Ping Liu Yi-Min Zhu Yan-Ting Wu Dan Zhang Bill Yee Vitaly AKushnir Zhi-Hong Yang Jia-Yin Liu Zi-jiang Chen Alan Thornhill Angie NBeltsos Johan Smitz John Frattarelli Alan Handyside Jie Qiao He-Feng Huang Obstetrics and Gynecology Hospital Institute of Reproduction and DevelopmentFudan UniversityShanghai 200092China Research Units of Embryo Original Diseases Chinese Academy of Medical Sciences(No.2019RU056)Shanghai 200092China Department of Clinical Research Yikon Genomics CompanyLtd.Suzhou 215000China Center for Reproductive Medicine Cheeloo College of MedicineShandong UniversityJinan 250022ShandongChina Department of Genetics and Metabolism Maternal and Child Health Hospital of Guangxi Zhuang Autonomous RegionNanning 530005GuangxiChina Division of Genetics and Genomics Boston Children’s HospitalHarvard Medical SchoolBostonMA 02115 Reproductive Medicine Center Department of Obstetrics and Gynecologythe First Affiliated Hospital of Anhui Medical UniversityHefei 230022AnhuiChina Center for Medical Genetics Hunan Key Laboratory of Medical GeneticsHunan Key Laboratory of Animal Models for Human DiseasesSchool of Life SciencesCentral South UniversityChangsha 410000HunanChina Department of Reproductive Endocrinology Women’s HospitalZhejiang University School of MedicineHangzhou 310058ZhejiangChina Reproductive and Genetic Hospital of CITIC-Xiangya Changsha 410000HunanChina Center of Reproductive Medicine Peking University Third HospitalBeijing 100191China Women’s Reproductive Health Research Key Laboratory of Zhejiang Province and Department of Reproductive Endocrinology Women’s HospitalZhejiang University School of MedicineHangzhou 310058ZhejiangChina Reproductive Partners Medical Group Redondo BeachCA 90277 Department of Obstetrics and Gynecology University of California IrvineOrangeCA 92868United States West Coast Fertility Centers Fountain ValleyCA California Excellent Fertility AnaheimCA State Key Laboratory of Reproductive Medicine the First Affiliated Hospital of Nanjing Medical UniversityNanjing 210029JiangsuChina School of Biosciences University of KentCanterburyKent CT27NJUnited Kingdom Vios Fertility Institute/Kindbody Wayne State UniversityDetroitMI 4820

The International Society of Reproductive Genetics(ISRG)assembled a workgroup made up of clinicians,clinical laboratory directors,and scientists for the purpose of creating the guidelines for preimplantation genetic testing(PGT).The most up-to-date information and clinical insights for the optimal PGT practice were incorporated in these *** are provided for embryologists,medical geneticists,clinical laboratorians,and other healthcare providers to improve the wellbeing of patients seeking assisted reproductive treatment and their offspring.

关键词： Preimplantation genetic testing Guidelines International Society of Reproductive Genetics(ISRG)

上海地区沿海岸线工程受相对海平面上升影响浅析

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上海地质 2000年第1期 6-10页

作者：丛林周健许彰珉同济大学地下建筑与工程系上海200092 福建地矿建设集团公司

由于受全球变暖和人类活动加剧的影响,预计到2050年上海地区海平面相对升高50～70cm,这会给包括堤坝在内的沿海岸线工程带来新的危害:包括地下水位抬升引起浅基础承载力下降、砂土地震液化加剧和建筑物震陷加重、降低堤坝标准、威胁堤... 详细信息

由于受全球变暖和人类活动加剧的影响,预计到2050年上海地区海平面相对升高50～70cm,这会给包括堤坝在内的沿海岸线工程带来新的危害:包括地下水位抬升引起浅基础承载力下降、砂土地震液化加剧和建筑物震陷加重、降低堤坝标准、威胁堤坝安全等问题。从定量的角度研究分析上述危害的严重性,提出综合措施。

关键词：上海地区海岸线工程海平面上升危害堤坎

Diagnostic Guidelines for Infertility

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Reproductive and Developmental Medicine 2020年第1期4卷 11-17页

作者： Zi-jiang Chen Jia-Yin Liu He-Feng Huang Jie Qiao Can-Quan Zhou Guo-Ning Huang Ying-Pu Sun Dong-Zi Yang Xiao-Yan Liang Qi Yu Yun Sun Zheng Li Li-Qing Fan cong-jian xu Yuan-Hua Huang xue-Hong Zhang Jing Yang Shao-Ming Lu Lin-Lin Cui Jun-Hao Yan Jin-Fang Lin Center for Reproductive Medicine Shandong UniversityJinan 250000China Clinical Center for Reproductive Medicine The First Affiliated Hospital of Nanjing Medical UniversityNanjing 211129China Department of Reproductive Medicine International Peace Maternity and Child Health HospitalShanghai Jiao Tong UniversityShanghai 200030China Department of Obstetrics and Gynecology Center for Reproductive MedicinePeking University Third HospitalBeijing 100191China Department of Obstetrics and Gynecology The First Affiliated Hospital of Sun Yat-Sen UniversityGuangzhou 510080China Chongqing City Institute of Reproduction and Genetics Chongqing 400010China Center for Reproductive Medicine The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450003China Department of Obstetrics and Gynecology Sun Yat-Sen Memorial HospitalSun Yat-Sen UniversityGuangzhou 510120China Reproductive Medicine Center The Sixth Affiliated Hospital of Sun Yat-Sen UniversityGuangzhou 510655China Department of Obstetrics and Gynecology Peking Union Medical College HospitalChinese Academy of Medical SciencesBeijing 100730China Center for Reproductive Medicine Renji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200001China Sperm Bank of Reproductive and Genetic Hospital of CITIC-XIANGYA Changsha 410008China Department of Gynecology Obstetrics and Gynecology Hospital of Fudan UniversityShanghai 200011China Reproductive Medicine Center The First Affiliated Hospital of Hainan Medical UniversityHaikou 570120China Department of Reproductive Medicine The First Hospital of Lanzhou UniversityLanzhou 730000China Center for Reproductive Medicine Renmin Hospital of Wuhan UniversityWuhan 430060China

Infertility seriously endangers the reproductive health of women at childbearing *** is defined as the failure to achieve successful pregnancy after 1 year or more of regular unprotected *** defined,infertility includes two aspects-failure to conceive or have a live *** guideline only addressed content relevant to the *** was proposed by the gynecological endocrine group of the Chinese Society of Obstetrics and Gynecology,Chinese Medical Association,based on relevant guidelines of the World Health Organization,the American Society for Reproductive Medicine,the National Institute for Health and Clinical Excellence,as well as the clinical practice in *** guideline was reviewed by experts and doctors from medical institutions at all levels,which is applicable to the diagnosis of infertility by physicians in obstetrics,gynecology,and andrology at various medical institutions nationwide.

关键词： Diagnostic Guidelines Etiological Classification Infertility Evaluation

神经营养因子3经受体切换促进大鼠脊髓损伤后神经功能的恢复

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中国组织工程研究 2025年第11期29卷 2268-2276页

作者：丛岩于健孙志德康大伟承德医学院附属医院急诊科河北省承德市067000

背景:神经营养因子是治疗脊髓损伤的新方法,调控自噬是其发挥作用的机制之一,但具体的信号通路尚不明确。目的:探讨神经营养因子3如何通过P75NTR/Trk C受体切换来调节少突胶质细胞的自噬以及促进脊髓损伤后神经功能恢复的作用,进一步明... 详细信息

背景:神经营养因子是治疗脊髓损伤的新方法,调控自噬是其发挥作用的机制之一,但具体的信号通路尚不明确。目的:探讨神经营养因子3如何通过P75NTR/Trk C受体切换来调节少突胶质细胞的自噬以及促进脊髓损伤后神经功能恢复的作用,进一步明确具体的分子机制。方法:将24只SD大鼠随机分为3组:假手术组、脊髓损伤组和神经营养因子3组,通过大鼠后肢神经功能评分来评估神经营养因子3对脊髓损伤大鼠的治疗效果,采用Western blot检测各组大鼠脊髓组织中神经营养因子3、Olig1、MBP蛋白以及自噬标记蛋白LC3B的表达水平。在细胞实验中,将少突胶质细胞接种在培养皿中,分为糖氧剥夺组、糖氧剥夺+神经营养因子3组、糖氧剥夺+神经营养因子3+P75NTR质粒组、糖氧剥夺+神经营养因子3+Trk C质粒组、糖氧剥夺+3-甲基腺嘌呤(自噬抑制剂)组及糖氧剥夺+雷帕霉素(自噬激活剂)组。光学显微镜观察少突胶质细胞形态变化,TUNEL染色观察细胞凋亡现象,Western blot检测Trk C受体、P75NTR、LC3B表达及PI3K/AKT/m TOR和AMPK/m TOR信号途径的磷酸化状态。结果与结论:(1)动物实验显示,与假手术组相比,脊髓损伤后神经营养因子3的表达显著增加(P<0.05);与脊髓损伤组相比,外源性神经营养因子3治疗能够加快大鼠神经功能的恢复(P<0.05),并增加Olig1和MBP蛋白的表达(P<0.05);(2)细胞实验发现,3 h是损伤早期与中后期的分界点,与糖氧剥夺组相比,糖氧剥夺+神经营养因子3组少突胶质细胞能够更长时间地维持其形态,Trk C受体在早期表达水平较低而中后期显著上调(P<0.05),P75NTR则在早期上调而中后期下调(P<0.05),自噬水平呈现出先升高后降低的趋势(P<0.05);(3)通过对比糖氧剥夺+神经营养因子3组、糖氧剥夺+雷帕霉素组和糖氧剥夺+3-甲基腺嘌呤组的细胞形态和TUNEL染色结果,发现单独促进或抑制自噬对少突胶质细胞的存活均有不利影响,而类似神经营养因子3这样调节自噬的方法则能最大限度地维持细胞存活;(4)神经营养因子3在早期通过P75NTR/AMPK/m TOR信号通路促进自噬,而在后期通过Trk C/PI3K/AKT/m TOR信号通路抑制自噬。根据上述结果,得到如下结论,即神经营养因子3可以通过P75NTR/Trk C受体的切换能够双向调控少突胶质细胞的自噬,从而维持细胞存活,有助于脊髓损伤后大鼠的神经功能恢复。

关键词：神经营养因子3 自噬少突胶质细胞受体切换凋亡脊髓损伤

Applications of scale-adaptive simulation technique based on one-equation turbulence model

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Applied Mathematics and Mechanics(English Edition) 2015年第1期36卷 121-130页

作者： Chang-yue xu Tao ZHOU cong-lei WANG jian-hong SUN College of Aerospace Engineering Nanjing University of Aeronautics & Astronautics

A modified scale-adaptive simulation （SAS） technique based on the Spalart- Allmaras （SA） model is proposed. To clarify its capability in prediction of the complex turbulent flow, two typical cases are carried out, i.e., the subcritical flow past a circular cylinder and the transonic flow over a hemisphere cylinder. For comparison, the same cases are calculated by the detached-eddy simulation （DES）, the delayed-detached eddy simulation （DDES）, and the XY-SAS approaches. Some typical results including the mean pressure coefficient, velocity, and Reynolds stress profiles are obtained and compared with the experiments. Extensive calculations show that the proposed SAS technique can give better prediction of the massively separated flow and shock/turbulent-boundary-layer interaction than the DES and DDES methods. Furthermore, by the comparison of the XY-SAS model with the present SAS model, some improvements can be obtained.

关键词： turbulence detached-eddy simulation scale-adaptive simulation cylinder

Advances in extraction and analysis of phenolic compounds from plant materials

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Chinese Journal of Natural Medicines 2017年第10期15卷 721-731页

作者： xu cong-cong WANG Bing PU Yi-Qiong TAO jian-Sheng ZHANG Tong Experiment Ceiter of Teaching and Learning Shanghai University of Traditional Chinese Medicine Shanghai 201203 China School of Phar nacy Shanghai University of Traditional Chinese Medicine Shanghai 201203 China

Phenolic compounds,the most abundant secondary metabolites in plants,have received more and more attention in recent years because of their distinct *** review summarizes different types of phenolic compounds and their extraction and analytical methods used in the recent reports,involving 59 phenolic compounds from 52 kinds of *** extraction methods include solid–liquid extraction,ultrasound-assisted extractions,microwave-assisted extractions,supercritical fluid extraction,and other *** analysis methods include spectrophotometry,gas chromatography,liquid chromatography,thin-layer chromatography,capillary electrophoresis,and near-infrared *** illustrating the specific conditions of the analytical methods,the advantages and disadvantages of each method are also summarized,pointing out their respective *** review provides valuable reference for identification and/or quantification of phenolic compounds from natural products.

关键词： Phenolic compounds Flavonoid Extraction Quantification Liquid chromatography Gas chromatography

An Actuarial Approach to Reload Option Valuation for a Non-tradable Risk Assets under Jump-diffusion Process and Stochastic Interest Rate

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Acta Mathematicae Applicatae Sinica 2018年第3期34卷 451-468页

作者： cong-cong xu Zuo-liang xu School of Information Renmin University of China Beijing 100872 China Department of Basic Course Shijiazhuang Institute of Railway Technology Shijiazhuang 050041 China

We use an actuarial approach to estimate the valuation of the reload option for a non-tradable risk asset under the jump-diffusion processes and Hull-White interest rate. We verify the validity of the actuarial approach to the European vanilla option for non-tradable assets. The formulas of the actuarial approach to the reload option are derived from the fair premium principle and the obtained results are arbitrage. Numerical experiments are conducted to analyze the effects of different parameters on the results of valuation as well as their differences from those obtained by the no-arbitrage approach. Finally, we give the valuations of the reload options under different parameters.

关键词： Non-tradable assets reload option actuarial approach jump-diffusion processes stochastic inter-est rate