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Chinese Society of Cardiology guidelines on the diagnosis and treatment of adult fulminant myocarditis

Science China(Life Sciences) 2024年第5期67卷 913-939页

作者： Chinese Society of Cardiology,Chinese Medical Association,Writing Group Jiangang Jiang Hongyang Shu Dao Wen Wang Rutai Hui Chenze Li Xiao Ran Hong Wang Jing Zhang Shaoping Nie Guanglin Cui Dingcheng Xiang Qun Shao shengyong Xu Discussion experts:Ning Zhou Yuming Li Wei Gao Yuguo Chen Yuan bian Guoping Wang Liming Xia Yan Wang Chunxia Zhao Zhiren Zhang Yuhua Zhao Jianan Wang Shaoliang Chen Hong Jiang Jing Chen Xianjin Du Mao Chen Yinxian Sun sheng Li Hu Ding Xueping Ma Hesong Zeng Li Lin shenghua Zhou Likun Ma Ling Tao Juan Chen Yiwu Zhou Xiaomei Guo 不详 Tongji Hospital Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Fuwai Hospital National Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100037China Zhongnan Hospital of Wuhan University Wuhan 430062China Fuwai Huazhong Cardiovascular Hospital Zhengzhou 450003China Beijing Anzhen Hospital Capital Medical UniversityBeijing 100029China Guangzhou General Hospital of Guangzhou Military Command Guangzhou 510010China Harbin Medical University Cancer Hospital Harbin 150081China Union Hospital Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China Taida Hospital Tianjin 300457China Peking University Third Hospital Beijing 100191China Qilu Hospital of Shandong University Jinan 250012China Kanghua Hospital DongguanGuangzhou 523080China Second Affiliated Hospital Zhejiang University School of Medicine Hangzhou 310003China Nanjing First Hospital Nanjing Medical UniversityNanjing 210006China Renmin Hospital of Wuhan University Wuhan 430060Wuhan West China Hospital Sichuan UniversityChengdu 610044China First Hospital of China Medical University Shenyang 110002China General Hospital of Ningxia Medical University Yinchuan 750003China The Second Xiangya Hospital Central South UniversityChangsha 410012China The First Affiliated Hospital of USTC University of Science and Technology of ChinaHefei 230002China The First Affiliated Hospital of Air Force Medical University Xi’an 710032China Central Hospital of Wuhan City Wuhan 430014China Tongji Medical College Huazhong University of Science and TechnologyWuhan 430030China

Fulminant myocarditis is an acute diffuse inflammatory disease of *** is characterized by acute onset,rapid progress and high risk of *** pathogenesis involves excessive immune activation of the innate immune system and formation of inflammatory *** to China’s practical experience,the adoption of the“life support-based comprehensive treatment regimen”(with mechanical circulation support and immunomodulation therapy as the core)can significantly improve the survival rate and long-term *** emphasis is placed on very early identification,very early diagnosis,very early prediction and very early treatment.

关键词： fulminant myocarditis guidelines life support-based comprehensive treatment regimen diagnosis treatment cytokine storm overactivation of immunity

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石蜡基相变材料在储热材料中应用的研究进展

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当代化工 2024年第2期53卷 435-439页

作者：张涛毕胜丛玉凤鲍金奇辽宁石油化工大学石油化工学院辽宁抚顺113001 中国石油抚顺分公司石油一厂辽宁抚顺113004

储热技术作为热能二次使用成为节约能源的一种新方式,储能技术种类繁多,相变储热技术是其中一种简单、高效的储热方式。相变储热技术是利用相变材料发生相变时吸收或释放的潜热进行热量储存,并且在换热过程中,系统温度近似恒定。作为相... 详细信息

储热技术作为热能二次使用成为节约能源的一种新方式,储能技术种类繁多,相变储热技术是其中一种简单、高效的储热方式。相变储热技术是利用相变材料发生相变时吸收或释放的潜热进行热量储存,并且在换热过程中,系统温度近似恒定。作为相变储热技术的核心部分,相变储能材料在热能储存技术领域的应用越来越受到重视。介绍了储热技术的分类及各种储热技术的优缺点,综述了石蜡基复合相变材料的分类及在储热领域的应用研究现状,并对其应用中存在的问题进行总结,最后对石蜡基相变材料的研究方向进行了展望。

关键词：石蜡基储热复合材料

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Clinical characteristics of flares in patients with rheumatoid arthritis after total hip and total knee arthroplasty

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Chinese Medical Journal 2023年第23期136卷 2877-2879页

作者： Liang Zhang cong Ma Hongchao Li Tao bian Siliang Man Yixin Zhou Department of Orthopedics Beijing Jishuitan HospitalBeijing 100035China Department of Rheumatology and Immunology Beijing Hospital of Traditional Chinese MedicineCapital Medical UniversityBeijing 100010China Department of Rheumatology Beijing Jishuitan HospitalBeijing 100035China

To the Editor:Introduction of conventional synthetic disease-modifying antirheumatic drugs(csDMARDs)has been highly efficacious in reducing the signs and symptoms of rheumatoid arthritis(RA)and in delaying or preventing structural joint ***,the development and clinical use of biological DMARDs(bDMARDs)and targeted synthetic DMARDs(tsDMARDs)have dramatically altered the prognosis of patients with RA,particularly when they are combined with a treat-to-target regimen(T2T).[1]Consequently,over the last two decades,the rates of total hip arthroplasty(THA)and total knee arthroplasty(TKA)remained stable or even decreased in these special patient ***,compared to patients with osteoarthritis,patients with RA have a higher risk of having worse functional outcomes and higher rates of complications after *** may be attributed to the complexity of the rheumatic disease process,including high disease activity,comorbidities,and immunosuppressive medications.[2]A key to making perioperative medication management decisions is to balance the risk of periprosthetic infection with the risk of a disease flare.

关键词： arthroplasty patients knee

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Targeting amyloid proteins for clinical diagnosis of neurodegenerative diseases

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Fundamental Research 2023年第4期3卷 505-519页

作者： Shenqing Zhang Hui Dong Jiang bian Dan Li cong Liu Bio-X Institutes Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders(Ministry of Education)Shanghai Jiao Tong UniversityShanghai 200030China School of Life Sciences and Biotechnology Shanghai Jiao Tong UniversityShanghai 200030China Interdisciplinary Research Center on Biology and Chemistry Shanghai Institute of Organic ChemistryChinese Academy of SciencesShanghai 201210China University of the Chinese Academy of Sciences Beijing 100049China State Key Laboratory of Bio-Organic and Natural Products Chemistry Shanghai Institute of Organic ChemistryChinese Academy of SciencesShanghai 200032China Bio-X-Renji Hospital Research Center Renji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200240China Zhangjiang Institute for Advanced Study Shanghai Jiao Tong UniversityShanghai 200240China.

Abnormal aggregation and accumulation of pathological amyloid proteins such as amyloid-β,Tau,and𝛼α-synuclein play key pathological roles and serve as histological hallmarks in different neurodegenerative diseases(NDs)such as Alzheimer’s disease(AD)and Parkinson’s disease(PD).In addition,various post-translational modifications(PTMs)have been identified on pathological amyloid proteins and are subjected to change during disease *** the central role of amyloid proteins in NDs,tremendous efforts have been made to develop amyloid-targeting strategies for clinical diagnosis and molecular classification of *** this review,we summarize two major strategies for targeting amyloid aggregates,with a focus on the trials in AD *** first strategy is a positron emission tomography(PET)scan of protein aggregation in the *** mainly focus on introducing the development of small-molecule PET tracers for specifically recognizing pathological amyloid *** second strategy is the detection of PTM biomarkers on amyloid proteins in cerebrospinal fluid and *** discuss the pathological roles of different PTMs in diseases and how we can use the PTM profile of amyloid proteins for clinical ***,we point out the potential technical challenges of these two strategies,and outline other potential strategies,as well as a combination of multiple strategies,for molecular diagnosis of NDs.

关键词： Amyloid aggregation Neurodegenerative diseases Clinical diagnosis Alzheimer’s disease Positron emission tomography(PET)tracer Tau Biomarker Post-translational modification

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基于GAF-HorNet的Φ-OTDR周界安防监测研究

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激光与光电子学进展 2024年第9期61卷 239-248页

作者：胡胜胡歆敏李莎莎吕朴初秦海鑫赵灿武明虎刘聪湖北工业大学电气与电子工程学院湖北武汉430068 华中科技大学光学与电子信息学院湖北武汉430074

相位敏感型光时域反射(Φ-OTDR)技术是一种具有高精度振动监测优点的分布式光纤传感技术,能够检测周界安防领域中的扰动事件。针对传统识别方法中需要人工提取振动信号特征,无法保留时间的相关性导致信息丢失的问题,提出一种基于GAF-Hor... 详细信息

相位敏感型光时域反射(Φ-OTDR)技术是一种具有高精度振动监测优点的分布式光纤传感技术,能够检测周界安防领域中的扰动事件。针对传统识别方法中需要人工提取振动信号特征,无法保留时间的相关性导致信息丢失的问题,提出一种基于GAF-HorNet的扰动事件识别方法,该方法无需特征提取步骤,能将一维振动信号通过格拉姆角场(GAF)转为二维图像,采用HorNet训练模型并进行识别分类。为了验证该算法的性能,选择4种经典算法训练模型进行对比实验。实验结果表明,该算法对背景噪声、石头敲击、石头划、树枝划、拉拽、攀爬等6类信号的平均识别准确率为93.56%,比现有的方法在识别率、误报率上有更好的表现。

关键词：光纤传感相位敏感光时域反射计格拉姆角场分类识别

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基于PMC指数模型的物流业发展政策量化评价研究

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物流科技 2024年第16期47卷 11-14页

作者：凌路通盛花英李江陵姚聪郝聪西安建筑科技大学公共管理学院陕西西安710055

为解决我国物流业发展过程中存在的现实问题,助力经济和社会发展。文章以物流业发展政策文本为研究对象,构建了PMC物流业发展政策评价指标体系和评价模型,并通过计算近5年国务院办公厅发布的4项物流业发展政策的PMC指数,对政策效力进行... 详细信息

为解决我国物流业发展过程中存在的现实问题,助力经济和社会发展。文章以物流业发展政策文本为研究对象,构建了PMC物流业发展政策评价指标体系和评价模型,并通过计算近5年国务院办公厅发布的4项物流业发展政策的PMC指数,对政策效力进行量化评价。研究发现,物流业发展政策总体效力较高,规划详实、科学合理,但也存在着缺少反馈机制、激励措施单一、缺乏物流业标准化规章等问题。基于此,文章建议增加反馈机制,优化激励措施,以进一步完善物流业标准化规章。

关键词：物流业发展政策 PMC指数模型政策评价量化评价

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基于非参数统计方法估算青藏高原臭氧背景浓度

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中国环境科学 2024年第8期44卷 4274-4281页

作者：谢民生吉东生殷秀峰辛金元万欣李健军张强弓布多丛志远西藏大学生态环境学院青藏高原生物多样性与生态环境保护教育部重点实验室西藏拉萨850000 中国科学院大气物理研究所北京100029 中国科学院西北生态环境资源研究院甘肃兰州730000 中国科学院青藏高原研究所北京100101 中国环境监测总站北京100012

基于Kolmogorov-Zurbenko(KZ)滤波和Robust Extraction of Baseline Signal(REBS)方法处理了青藏高原纳木错站和珠峰站多年连续的近地面臭氧原始观测数据.通过合理选择KZ滤波器和REBS滤波窗口与带宽,成功去除了臭氧时间序列中的短期变动... 详细信息

基于Kolmogorov-Zurbenko(KZ)滤波和Robust Extraction of Baseline Signal(REBS)方法处理了青藏高原纳木错站和珠峰站多年连续的近地面臭氧原始观测数据.通过合理选择KZ滤波器和REBS滤波窗口与带宽,成功去除了臭氧时间序列中的短期变动,提取了代表两站近地面臭氧背景浓度信号.结果表明,KZ滤波法得到的纳木错站和珠峰站臭氧年平均背景浓度分别为89.71μg/m^(3)和88.98μg/m^(3);REBS方法得到的分别为89.62μg/m^(3)和88.52μg/m^(3).两种方法得到的背景臭氧浓度一致性较好,都呈现出相似的季节变化规律.4~5月臭氧浓度较高,而季风期间则较低.KZ滤波更侧重反映长期趋势和季节周期性变化,而REBS在局部污染时段的表现更好.两种非参数统计方法均可有效应用于背景区域臭氧时间序列分析,为监测和防治臭氧污染提供重要依据.

关键词：臭氧背景浓度 KZ滤波 REBS 青藏高原

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水产养殖环境中农兽药物的污染暴露水平及其风险影响评价

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环境科学 2024年第1期45卷 151-158页

作者：张楷文张海燕孔聪顾润润田良良杨光昕王媛陈冈沈晓盛中国水产科学研究院东海水产研究所上海200090 上海海洋大学食品学院上海201306 上海市金山区水产技术推广站上海201599

为探究水产养殖环境中农兽药物污染暴露水平及其对生态环境的风险影响,以上海地区水产养殖环境为例,于2022年7~9月采集40家主要水产养殖场中水体、底泥以及投入品,采用超高压液相色谱-静电场轨道离子阱质谱法分析其农兽药物的含量及种类... 详细信息

为探究水产养殖环境中农兽药物污染暴露水平及其对生态环境的风险影响,以上海地区水产养殖环境为例,于2022年7~9月采集40家主要水产养殖场中水体、底泥以及投入品,采用超高压液相色谱-静电场轨道离子阱质谱法分析其农兽药物的含量及种类,并通过风险商值(RQ)法对底泥和水体中的农兽药物污染进行生态风险评估.结果表明,204份样品(水样72份、泥样72份和投入品60份)中共筛出13种药物,分别是扑草净、多菌灵、西草净、扑灭津、氟苯尼考、西玛津、金刚烷胺、地西泮、甲氧苄啶、环丙沙星、氧氟沙星、甲苯咪唑和恩诺沙星,其中水样中12种,浓度在0.016~2.084μg·L^(-1)之间.泥样中7种,含量在0.018~23.101μg·kg^(-1)之间.投入品中4种,含量在1.979~101.940μg·kg^(-1)之间.水体与底泥同时发现的药物有7种.风险商值评价结果显示,农兽药残留在水产养殖场底泥和水体中均存在高中风险,其中生态风险最高的药物为多菌灵,RQ值分别为3.848和1.580,表现为高风险.建议加强养殖环境中农兽药物外源进入的控制与管理,以保护水产养殖环境的生态系统健康.

关键词：养殖环境农兽药暴露水平风险评估上海地区

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Divergent synthesis of aryl amines and dihydroquinazolinones via electrochemistry-enabled rhodium-catalyzed C–H functionalization

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中国科学:化学英文版 2023年第10期66卷 2863-2870页

作者： Yi-Kang Xing Zhen-Hua Wang Ping Fang cong Ma Tian-sheng Mei State Key Laboratory of Organometallic Chemistry Shanghai Institute of Organic ChemistryUniversity of Chinese Academy of SciencesShanghai 200032China

Electrochemistry-enabled rhodium-catalyzed C–H amination and amination cyclization of arene assisted by a weakly coordinating amide have been reported. Additionally, aryl amines and dihydroquinazolinones could be obtained selectively by controlling the electric current. Mechanistic studies suggested that the amination reaction likely involves an electrochemical oxidation-induced reductive elimination of a high valent rhodium intermediate, which led to the amination reaction even proceeding smoothly at room temperature.

关键词： organic electrochemistry rhodium catalysis C-H functionalization divergent synthesis

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A boundary surrogate model for micro/nano grooved surface structure applied in turbulence flow control over airfoil

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Chinese Journal of Aeronautics 2022年第2期35卷 62-73页

作者： Liyue WANG cong WANG Shuyue WANG sheng QIN Gang SUN Bo YOU Yongjian ZHONG Department of Aeronautics&Astronautics Fudan UniversityShanghai 200433China Department of Material Science Fudan UniversityShanghai 200433China AECC Commercial Aircraft Engine Co. Ltd.Shanghai 200241China

The application of grooved surface structure is an emerging and effective means in turbulence flow ***,for a realistic configuration,the global flow field described directly by simple application of massive grids makes it unfeasible to *** this paper,a boundary surrogate model reproducing the effect of microscopic near-wall region is proposed to improve computational *** surrogate model trained with Lattice Boltzmann Method(LBM)considering the rarefied effect based on real micro/nanoflow field is new among literature,which accurately shows flow characteristics of the micro/nano *** this approach,numerical simulations via Reynolds-averaged Navier Stokes equations with modified wall boundary condition are performed in subsonic and transonic *** results show that micro/nano grooved surface structure has the effect of delaying transition from laminar to turbulence,thus reducing the skin friction *** of turbulence intensity and turbulence kinetic energy shows that the near-wall flow field of grooved airfoil is more stable compared with that of the smooth *** reducing rate of maximum turbulent intensity reaches 13.39%.The paper shows a perspective for further application of micro/nano groove structure to turbulence flow control in aircraft design by providing an accurate and efficient simulation method.

关键词： Boundary modeling CFD Drag reduction Flow control Microstructure

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