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Hepatobiliary & Pancreatic Diseases International 2024年第2期23卷 117-122页

作者： Xin Yang Lu Lu Wen-Wei Zhu Yi-Feng Tao cong-Huan shen Jin-Hong Chen Zheng-Xin Wang Lun-Xiu Qin Hepatobiliary Surgery and Liver Transplantation Centers Department of General SurgeryHuashan Hospital&Cancer Metastasis InstituteFudan UniversityShanghai 200040China

Hepatectomy is still the major curative treatment for patients with liver ***,it is still a big challenge to remove the tumors in the central posterior area,especially if their location involves the retrohepatic inferior vena cava and hepatic *** vivo liver resection and auto-transplantation(ELRA),a hybrid technique of the traditional liver resection and transplantation,has brought new hope to these patients and therefore becomes a valid alternative to liver *** to its technical difficulty,ELRA is still concentrated in a few hepatobiliary centers that have experienced surgeons in both liver resection and liver *** efficacy and safety of this technique has already been demonstrated in the treatment of benign liver diseases,especially in the advanced alveolar ***,the application of ELRA for liver malignances has gained more ***,standardization of clinical practice norms and international consensus are still *** prognostic impact in these oncologic patients also needs further *** this review,we summarized the principles and recent progresses on ELRA.

关键词： Ex vivo liver resection Liver auto-transplantation Oncology Liver malignancies

RNF187 governs the maintenance of mouse GC-2 cell development by facilitating histone H3 ubiquitination at K57/80

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Asian Journal of Andrology 2024年第3期26卷 272-281页

作者： Bing-Ya Xu Xiang-Ling Yu Wen-Xin Gao Ting-Ting Gao Hao-Yue Hu Tian-Tian Wu cong shen Xiao-Yan Huang Bo Zheng Yi-Bo Wu Human Reproductive and Genetic Center Affiliated Hospital of Jiangnan UniversityWuxi 214122China State Key Laboratory of Reproductive Medicine Department of Histology and EmbryologySchool of Basic Medical SciencesNanjing Medical UniversityNanjing 211166China Changzhou Maternal and Child Health Care Hospital Changzhou Medical CenterNanjing Medical UniversityChangzhou 213000China State Key Laboratory of Reproductive Medicine Center for Reproduction and GeneticsSuzhou Municipal HospitalThe Affiliated Suzhou Hospital of Nanjing Medical UniversityGusu SchoolNanjing Medical UniversitySuzhou 215002China

RING finger 187(RNF187),a ubiquitin-ligating(E3)enzyme,plays a crucial role in the proliferation of cancer ***,it remains unclear whether RNF187 exhibits comparable functionality in the development of germline *** investigate thepotential involvement of RNF187 in germ cell development,we conducted interference and overexpression assays using GC-2 cells,a mouse spermatocyte-derived cell *** findings reveal that the interaction between RNF187 and histone H3 increases theviability,proliferation,and migratory capacity of GC-2 ***,we provide evidence demonstrating that RNF187 interactswith H3 and mediates the ubiquitination of H3 at lysine 57(K57)or lysine 80(K80),directly or indirectly resulting in increasedcellular *** is a study to report the role of RNF187 in maintaining the development of GC-2 cells by mediatinghistone H3 ubiquitination,thus highlighting the involvement of the K57 and K80 residues of H3 in the epistatic regulation of *** discoveries provide a new theoretical foundation for further comprehensive investigations into the functionof RNF187 in the reproductive system.

关键词： GC-2 cell histone H3 RNF187 ubiquitination

特殊荷载作用下40 m预应力混凝土T梁研究

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林业建设 2024年第1期42卷 72-76页

作者：沈聪国家林业和草原局西南调查规划院云南昆明650031

结合我国水电站进场公路建设情况,提出特殊荷载运输车辆作用下标准跨径40 m T梁上部构造研究方法,探讨适用于电站进场公路的安全、适用、经济和耐久的桥梁结构方案,以供其他同类工程参考。

关键词：特种验算荷载 T梁设计承载能力

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基于大件运输下连续刚构桥承载能力分析

林业建设 2024年第1期42卷 68-71页

作者：叶兵沈聪国家林业和草原局西南调查规划院云南昆明650031

以某电站进场道路上的连续刚构桥结构计算为工程背景,通过对该桥在特殊重载车辆下承载能力分析,并对不同荷载工况作用下,桥梁结构受压区高度变化进行了比较,提出了正截面抗弯承载力分析方法,为大件运输下连续刚构桥承载能力分析提供了... 详细信息

以某电站进场道路上的连续刚构桥结构计算为工程背景,通过对该桥在特殊重载车辆下承载能力分析,并对不同荷载工况作用下,桥梁结构受压区高度变化进行了比较,提出了正截面抗弯承载力分析方法,为大件运输下连续刚构桥承载能力分析提供了参考作用。

关键词：预应力连续刚构桥大件运输有限元模型受压区高度

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闽东畲族药膳的调查研究及开发应用思考

海峡药学 2024年第8期36卷 44-48页

作者：沈悰祺山西中医药大学山西太原030024

目的对闽东畲族药膳进行调查研究。方法通过走访和问卷调查等方式对闽东畲族药膳习用方及畲族药膳常用品种进行调查和研究。结果共收集到畲族药膳习用方20条,整理出药膳用的畲药品种30种,总结了闽东畲族药膳的特点及开发利用现状,并提... 详细信息

目的对闽东畲族药膳进行调查研究。方法通过走访和问卷调查等方式对闽东畲族药膳习用方及畲族药膳常用品种进行调查和研究。结果共收集到畲族药膳习用方20条,整理出药膳用的畲药品种30种,总结了闽东畲族药膳的特点及开发利用现状,并提出了产业化发展思路。结论理清了畲族药膳习用方及药膳常用畲药品种。可为闽东畲族药膳传承与发展提供一定的参考。

关键词：闽东畲族药膳

基于定量CT的肺血栓体积评估中高危急性肺栓塞的诊断价值

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西安交通大学学报（医学版） 2024年第1期45卷 126-132页

作者：姚彦娥李岩松王雄慧黄晓旗任涛冯筠郭佑民沈聪延安大学附属医院影像科陕西延安716000 西安国际医学中心医院核医学科陕西西安710000 西北大学计算机学院陕西西安710127 西安交通大学第一附属医院影像科陕西西安710061

目的探讨基于计算机辅助定量的肺血栓体积(pulmonary embolism volume,PEV)在识别中高危急性肺栓塞(acute pulmonary embolism,APE)中的诊断价值。方法回顾性收集2017年1月至2020年12月延安大学附属医院可疑APE并经计算机断层肺动脉成像... 详细信息

目的探讨基于计算机辅助定量的肺血栓体积(pulmonary embolism volume,PEV)在识别中高危急性肺栓塞(acute pulmonary embolism,APE)中的诊断价值。方法回顾性收集2017年1月至2020年12月延安大学附属医院可疑APE并经计算机断层肺动脉成像(CTPA)确诊的患者共143例,按2018中国《肺血栓栓塞症诊治与预防指南》分为低危组(n=88)和中高危组(n=55),收集患者的基本人口学资料、临床表现及血清中的N末端-B型钠尿肽前体(NT-proBNP)、D-二聚体水平。根据CTPA图像人工评价肺血栓栓塞程度,得到肺动脉阻塞指数(pulmonary artery obstruction index,PAOI)。采用“数字肺”肺血栓检测工具分割血栓,计算PEV。比较低危组与中高危组之间临床指标、实验室指标及PAOI、PEV的差异,采用受试者工作特征(ROC)曲线分析PAOI、PEV在识别中高危APE中的诊断价值,采用Logistic回归分析筛选中高危APE的独立危险因素,并建立不同的模型。结果中高危APE组较低危组年龄大、舒张压低(P<0.05),D-二聚体和NT-proBNP水平高(P<0.05),血小板计数、动脉血氧分压和动脉血二氧化碳分压低(P<0.05),PAOI和PEV高(P<0.001)。ROC曲线分析显示,PEV、PAOI识别中高危APE的曲线下面积分别为0.809(95%CI:0.734~0.884)、0.753(95%CI:0.667~0.839)。Logistic回归分析显示,PEV、NT-proBNP是中高危APE的独立危险因素(P<0.05)。结论PEV、NT-proBNP是预测中高危APE的独立危险因素。

关键词：急性肺栓塞危险分层肺血栓体积计算机辅助定量

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一种SOP端口不平衡时直流侧电压脉动抑制策略

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电测与仪表 2024年第3期61卷 95-101页

作者：张国荣汤彬沈聪王泰文徐晨林夏子鹏合肥工业大学电气与自动化工程学院合肥230009 广东电网有限责任公司珠海供电局广东珠海519031

当柔性多状态开关(SOP)端口电压不平衡时,会引起直流侧电压的波动,给整个系统的稳定性带来很大的影响。根据SOP的数学模型,对波动的原因进行了分析,提出一种基于二阶滑模控制的直流侧电压波动抑制策略;通过引入基于非线性干扰观测器的... 详细信息

当柔性多状态开关(SOP)端口电压不平衡时,会引起直流侧电压的波动,给整个系统的稳定性带来很大的影响。根据SOP的数学模型,对波动的原因进行了分析,提出一种基于二阶滑模控制的直流侧电压波动抑制策略;通过引入基于非线性干扰观测器的电容补偿器装置,对参考电压电流进行精确地跟踪。考虑多种端口电压不平衡的条件,在MATLAB/Simulink中搭建SOP仿真模型,仿真结果表明,该方法对直流侧电压波动抑制有明显的效果。

关键词：柔性多状态开关端口不平衡滑模控制电容器补偿装置

Diverse interactions of five core type Ⅲ effectors from Ralstonia solanacearum with plants

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Journal of Genetics and Genomics 2023年第5期50卷 341-352页

作者： shen cong Jun-Zhou Li Zheng-Zhong Xiong Hai-Lei Wei Key Laboratory of Microbial Resources Collection and Preservation Ministry of Agriculture and Rural AffairsInstitute of Agricultural Resources and Regional PlanningChinese Academy of Agricultural SciencesBeijing 100081China

Ralstonia solanacearum is a widespread plant bacterial pathogen that can launch a range of type Ⅲ effectors(T3Es)to cause *** this study,we isolate a pathogenic *** strain named P380 from tomato *** out of 12 core T3Es of strain P380 are introduced into Pseudomonas syringae DC3000D36E separately to determine their functions in interacting with ***3000D36E that harbors each effector suppresses FliC-triggered Pti5 and ACRE31 expression,ROS burst,and callose ***,RipU,and RipW elicit cell death as well as upregulate the MAPK cascades in Nicotiana *** derivatives RipC1^(△DDXDX(T/V))and RipW^(△DDKXXQ)but not RipAE^(K310R) fail to suppress ROS ***,RipAE^(K310R) and RipW^(△DDKXXQ) retain the cell death elicitation *** and RipW are associated with salicylic acid and jasmonic acid pathways,*** and RipAQ significantly promote the propagation of DC3000D36E in *** five core T3Es localize in diverse subcellular organelles of nucleus,plasma membrane,endoplasmic reticulum,and Golgi *** suppressor of G2 allele of Skp1 is required for RipAE but not RipU-triggered cell death in *** results indicate that the core T3Es in *** play diverse roles in plantpathogen interactions.

关键词： Ralstonia solanacearum TypeⅢsecretion system Effectors PTI ETI

Forming and breaking the ceiling of inlet gas velocity regarding to separation efficiency of cyclone

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Particuology 2023年第8期79卷 85-94页

作者： Shaoxing Han Jingxuan Yang Ronghua Zhang cong shen Wenhao Lian Wei Zhang Xiaogang Hao College of Chemical Engineering and Technology Taiyuan University of TechnologyTaiyuan030024China Avic Xinxiang Aviation Industry(Group)Co LtdXinxiang453002China School of Chemistry and Chemical Engineering North University of ChinaTaiyuan030051China

The maximum-efficiency inlet velocity(MEIV)is a ceiling of inlet gas velocity that defines separation efficiency during cyclone design and *** and computational fluid dynamics(CFD)simulation exhibited that an apex cone at the dust outlet can break the ceiling and improve the sepa-ration *** phenomenon is closely related to the effect of excessive high inlet gas velocity on the back-mixing escape of fine particles,which is the final result of back mixing,entrainment by the rapid upward airflow,and secondary separation of the inner *** the center of the inner vortex,the airflow rotates slowly and moves rapidly *** elevator type of airflow delivers re-entrained particles to the vortex finder.A higher inlet gas velocity accelerates the elevator,causing more entrained particles to *** explains the decrease in efficiency at an excessively high inlet gas *** an apex cone is installed at the dust outlet,the back-mixing is significantly weakened because the vortex core is bounded to the center of separator,while the transport effect of rapid upward airflow is weakened by the decrease in axial velocity in the ***,particle escape is weakened even at excessive high inlet gas ***,the centrifugal effect is enhanced because of increased tangential velocity of the gas and ***,the ceiling of inlet gas velocity is broken.

关键词： Cyclonese parator Inletgas velocity Back mixing escape Precession vortex core Axial velocity

7.5μm像元间距红外探测器三维电极的制备与应用

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红外 2024年第1期45卷 12-19页

作者：王格清申淙冯晓宇张轶华北光电技术研究所北京100015 中国电子科技集团公司第四十五研究所北京100176

采用现有读出电路电极生长设备和直写式光刻设备开发了三维电极的制备工艺。在制备过程中,首先在读出电路表面制备三维电极,在碲镉汞芯片端生长铟饼,然后通过倒装互连工艺可以实现7.5μm像元间距的1k×1k碲镉汞芯片与读出电路的互连。... 详细信息

采用现有读出电路电极生长设备和直写式光刻设备开发了三维电极的制备工艺。在制备过程中,首先在读出电路表面制备三维电极,在碲镉汞芯片端生长铟饼,然后通过倒装互连工艺可以实现7.5μm像元间距的1k×1k碲镉汞芯片与读出电路的互连。可变参数包括金属生长角度、生长速率、生长厚度以及金属种类等。经研究发现,通过该工艺制备的7.5μm像元间距的三维电极高度可达到3.8μm,高度非均匀性小于3%,可以经受7.6×10^(-5)N的压力。三维电极的应用,降低了倒装互连工艺对HgCdTe芯片平坦度和互连设备精度的要求,大幅提高了7.5μm像元间距红外探测器的互连成品率。

关键词：碲镉汞 7.5μm像元间距三维电极