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世界核心医学期刊文摘（皮肤病学分册） 2005年第6期1卷 52-52页

作者： combemale p. Consort T. Denis-Thelis L. 潘敏 Dep.rtment of Dermatology Desgenettes Hospital 108 Bd Pinel 69003 Lyon France

The main causes of arteriop.thy in young p.tients include drugs, metabolic diseases, p.eudoxanthoma elasticum and Buerger’s disease. Arteritis due to Cannabis indica was first rep.rted in 1960, and the role of this drug as a risk factor for arteritis was confirmed in several subsequent p.blications. A 38- year-old smoker with no p.evious contributory medical history excep. for long-standing cannabis abuse develop.d a dry necrotic lesion of the left big toe. Imaging examinations revealed p.oximal arteriop.thy of the lower limbs that p.edominated on the left side. He had no atherogenic or thrombogenic risk factors, and no signs of p.eudoxanthoma elasticum were found. Remarkably, the develop.ent of arteritis p.ralleled cannabis abuse. The course was slowly favourable after weaning from the drug, vasodilator treatment and hyp.rbaric oxygen therap.. Desp.te some subtle clinical differences (more p.oximal than distal involvement), cannabis arteritis may be considered as a p.rticular form of Buerger’s disease, where cannabis, along with tobacco, seems to cause arterial lesions. Along with the noxious effects of cannabis on vessels, a role for contaminating arsenic is also p.ssible. Cannabis arteritis is not widely known, but may p.ove not to be so rare if one considers consump.ion of cannabis besides that of tobacco.

关键词：动脉炎印度大麻动脉病弹性假黄瘤干性坏疽脉管近端的代谢疾病高压氧治疗吸食者

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疱疹样脓疱病合并Ondinecurse(法国)

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世界核心医学期刊文摘（皮肤病学分册） 2005年第10期1卷 20-20页

作者： Doebelin B Estival J.L Nau A. et al p. combemale 李晓莉 Service de Dermatologie Hpital d'Instruction des Armées Desgenettes 108 boulevard Pinel 69275 Lyon Cedex 03France

Introduction. Imp.tigo herp.tiformis is a rare dermatitis that occurs during p.egnancy and may be life threatening for both mother and child. In this case rep.rt, we p.esent an Ondine curse involving the baby, and the good resp.nse to isotretinoine. Case rep.rt. A first p.egnancy, 26 year-old woman develop.d at 8 months a widesp.ead skin lesion involving the medial side of the thighs, abdomen and intertriginous areas, with a severe systemic toxic condition and fever. Diagnosis of imp.tigo herp.tiformis was made and corticosteroids, methotrexate and cyclosp.rinewere unsuccessful. Isotretinoine rap.dly imp.oved the p.tient with good control of the disease. The full term baby had an Ondine curse. Discussion. Our case is typ.cal of imp.tigo herp.tiformis. Maternal and infant comp.ication may be life threatening and we rep.rt a real Ondine curse the etiology of which remains unknown. Moreover, this observation is unusual because the lesions did not clear desp.te delivery and good treatment. In our op.nion, the great imp.ovement with isotretinoine would suggest it could be used as first line treatment.

关键词：疱疹样脓疱病 Ondinecurse 异维甲酸全身中毒症状甲氨蝶呤足月产初产妇环孢素一线用药皮质激素

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