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Evaluation of frequency-lowering algorithms for intelligibility of Chinese speech in hearing-aid users

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Progress in Natural science:Materials International 2009年第6期19卷 741-749页

作者： Xianbo Xiao a, Hui Zhang a, Guangshu Hua, Chunhong Liu b, Jia Liu c a biomedical engineering, Tsinghua University, Room 209, Medical Tech. Bld., Beijing 100084, China b Department of Otolaryngology, Xuanwu Hospital, Beijing 100053, China c Bo Na Feng Medical instrument Co., Ltd., Beijing 100028, China [a]biomedical engineering Tsinghua University Room 209 Medical Tech. Bld. Beijing 100084 China [b]Department of Otolaryngology Xuanwu Hospital Beijing 100053 China [c]Bo Na Feng Medical Instrument Co. Ltd. Beijing 100028 China

Despite the attention being given to and the knowledge of the benefits of evaluating frequency-lowering algorithms for hearing-impaired people, the causality between these algorithms and their benefits is still not clear. This is aggravated by the fact that comparative research on the methodologies and skills required for fitting an appropriate algorithm to individual patients is lacking. Against this back-drop, the current study has attempted to make progress in this area. In this experiment, six experienced traditional hearing-aid users with severe impairments in the high frequencies were fitted with two different frequency-lowering methods, and weekly hearing tests were conducted to track the benefits of such methods. After the experiment, five of the listeners accepted the frequency-lowering algorithms. Both methods showed superior results when compared with the listeners’ own hearing aids in most of the tests, and the segmented compression algorithm was indicated to have better "anti-noise" quality and speech intelligibility improvement capabilities. A preference for the application of proportional compression to unvoiced speech was also found in this algorithm. Unlike in previous studies, all speech materials here are recorded in Chinese. Therefore, the results could also be used to evaluate the benefits of frequency-lowering to the intelligibility of Chinese speech for patients. As a result, an improvement was found, especially in the recognition of consonants. Moreover, no adverse effect was found in intonation recognition.

关键词： Hearing aid Frequency-lowering Speech intelligibility

A water-fat separation imaging method for the brain on low field magnetic resonance imaging

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Journal of Pharmaceutical Analysis 2009年第4期21卷 272-276页

作者： Hong-jun Tian1,Si-ping Chen2,Tian-fu Wang2,Xian-fen Diao2,Chong-xun Zheng1 1.Key Laboratory of biomedical Information engineering of Education Ministry,Xi’an Jiaotong University,Xi’an 710049 2.college of Information engineering,Shenzhen University,Shenzhen 518060,China Key Laboratory of biomedical Information engineering of Education Ministry Xi'an Jiaotong University Xi'an 710049 China college of Information engineering Shenzhen University Shenzhen 518060 China

Water-fat separation is a particularly important problem for magnetic resonance *** many methods have been proposed,the reliability is still *** this work,we have presented a method based on the combination of the branch-cut method and multigrid algorithm to get a more robust performance of water-fat ***,the branch-cut method is applied to identify residues,which violates the requirement that the interacting phase gradient around a closed path be *** and branches are marked to be zeros and filled to the weighting factor ***,the unwrapped phase array can be given by the multigrid ***,the Dixon method for water-fat separation is applied to the unwrapped phase *** for brain scanning on the 0.3T low field MRI system demonstrate the successful application of the proposed method.

关键词： water-fat separation Dixon weighted multigrid unwrapping

维普期刊数据库

Effects of cecropin-XJ on growth and adherence of oral cariogenic bacteria in vitro

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中华医学杂志(英文版) 2005年第2期000卷 69-74页

作者： HAO Yu qing, ZHOU Xue dong, XIAO Xiao rong, LU Jun jun, ZHANG Fu chun, HU Tao, WU Hong kun and CHEN Xin mei Key Laboratory for Oral biomedical engineering, Ministry of Education, West China of Stomatology college, Sichuan University, Chengdu 610041, China Key Laboratory of Molecular Biology, college of Life science and Technology, Xinjiang University, Urumq, 830000, China Key Laboratory for Oral biomedical engineering Ministry of Education West China of Stomatology College Sichuan University Chengdu 610041 China Key Laboratory of Molecular Biology College of Life Science and Technology Xinjiang University Urumq 830000 China

Background CecropinXJ belongs to cecropinB, which is the most potent antibacterial peptide found naturally The aim of this study was to investigate the effects of cecropinXJ on growth and adherence of oral cariogenic bacteriaMethods Four oral cariogenic bacteria (Streptococcus mutans, Lactobacillus acidophilus, Actinomyces viscosus and Actinomyces naeslundii) were chosen for this experiment The minimal inhibitory concentrations (MICs) and reductive percent of bacterial growth were used to assay the antibacterial activity of cecropinXJ Mammalian cytotoxicity of cecropinXJ was tested with human periodontal membrane fibroblasts by tetrazolium (MTT) colorimetric assay The bacterial morphological changes induced by cecropinXJ were examined on scanning electron microscope (SEM) The influence of cecropinXJ on bacterial adhesion to salivacoated hydroxyapatite (SHA) was measured by scintillation countingResults The MICs of cecropinXJ for inhibition of the growth of four bacteria ranged from 40 to 428 μmol/L with the highest susceptible to A naeslundii and the lowest susceptible to L acidophilus At pH 68, 55 and 82, 1/2 MIC of cecropinXJ reduced the number of viable bacteria by 409%, 678% and 328% for S mutans and by 281%, 572% and 379% for L acidophilus The activities against Smutans and L acidophilus increased at pH 55 compared with pH 68 (P005, respectively), whereas almost no reduction counts were detected in the presence of 20% serum for both bacteria (P>005, respectively) Mammalian cytotoxicity of cecropinXJ from 10 to 100 μmol/L exhibited no cytotoxicity against human periodontal membrane fibroblasts (P>005) Bacterial morphological changes induced by MIC of cecropinXJ examined on SEM showed cell s

关键词： cecropin-XJ · cariogenic agents · anti bacterial agents · bacterial adhesion · Durapatite

A distributed optical fiber bi-directional strain-displacement sensor

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Progress in Natural science:Materials International 2003年第1期 76-79页

作者： LIU Tiegen , LI Chuan, ZHANG Yimo, JIANG Junfeng, DING Yongkui, DING Sheng, CHENG Yaxiong and ZHENG Guizhong (The Key Laboratory of Optoelectronics Information science & Technology of Educational Ministry, Institute of Modern Optics instrument, Tianjin University, Tianjin 300072, China college of Information and Automatic engineering, Kunming University of science and Technology, Kunming 650051, China) The Key Laboratory of Optoelectronics Information science & Technology of Educational Ministry Institute of Modern Optics Instrument Tianjin University Tianjin 300072 China college of Information and Automatic engineering Kunming University of Science and Technology Kunming 650051 China

Abstract A distributed optical fiber strain-displacement sensor is developed, which consists of an optical fiber gauge of strain-dis-placement and an optical time domain reflectometer (OTDR). The operational principle is the modulation of fiber loss in OTDR, i. e. thestrain and displacement in monitoring position are obtained from the bending loss of optical fiber bonded on the optical fiber gauge of strain-displacement. After examining the strain and displacement in the cantilever and the micro displacement rack respectively, the result indi-cates that the distributed optical fiber gauge of strain-displacement can monitor strains or displacements in different sensitive lengths. Thekey technique for measuring bi-directional strain-displacement is the pretreatment of bending of the freely suspended optical fibers, whichcan be identified with OTDR by inserting time delay optical fiber.

关键词： optical fiber bi-directional gauge of strain-displacement optical time domain reflectometer (OTDR) fiber bending loss strain displacement.

Design and Fabrication of Integrated-Optic Disk Pickup on LiNbO3 Substrate

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Chinese Journal of Lasers 2001年第3期 44-46页

作者： DING Guilan CHEN Caihe ZHANG Delong CUI Yuming LIU Jie (college of Precision instrument and Opto Electronics engineering, Tianjin University, Key Laboratory of Opto electronics Information Technical science, EMC, Tianjin 300072, China)

An integrated optic disk pickup device has been realized on a LiNbO 3 substrate. The device is constructed by integrating an aplanatic double convex aspherical waveguide lens (ADCAWL), a twin grating focusing beam splitter (TGFBS) and two waveguide deflecting prisms (WDP) on a Ti∶LiNbO 3 planar waveguide. The design considerations and fabrication of prototype device are summarized.

关键词： integrated\|optic disk pickup waveguide lens beam splitter plannar waveguide

Michelson all-fiber acceleration seismic geophone with dual-optic routes

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Michelson all-fiber acceleration seismic geophone with dual-...

Selective inhibition of Hepatocarcinoma cells by apatite nanoparticles

Asia-pacific Optical Communications 2004

作者： Yanjun Zhang* Caihe Chen Yongjie Hao Guilan Ding Yuming Cui college of Precision instrument and Opto-electronics engineering Tianjin University Key Laboratory of Opto-electronics Information Technical science EMC

This paper describes a Michelson all-fiber acceleration seismic geophone with dual-optic routes. Compared with the single-optic route structure, dual-optic routes geophone exhibits wider frequency res

关键词： acceleration seismic geophone Michelson interferometer PTAC

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Chinese Journal of biomedical engineering(English Edition) 2002年第2期11卷 67-71页

作者： SUN En jie 1, LI Shi pu 2 ,YAN Yu hua 2 CAO Xian ying 2,FENG Ling yun 2 , XIONG Xian li 2,ZHANG Zhu 2 1 college of Materials science and engineering 2 biomedical Materials And engineering Center Wuhan University of science and Technol

The effects of HAP nanoparticles on growth of primary normal animal liver cells and on growth of hepatocarcinoma cell line Bel 7402 in vitro were studied respectively and were compared with each *** results showed that HAP nanoparticles in certain concentration inhibited growth of cancer cells significantly while did not inhibite normal cells in the same *** inhibition ratio was as high as very high dosage of *** was concluded that HAP nanoparticles can selectively inhibited cancer cells.

关键词： HAP nanoparticles cancer cells inhibition of cancer cell

维普期刊数据库

Methods of Gas-solid Two-phase Flow Velocity Measurement

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Methods of Gas-solid Two-phase Flow Velocity Measurement

Study of a Novel Algorithm on ADCP System

2011 Chinese Control and Decision Conference（CCDC）

作者： Wang Yutao and Yang Gang are with the Institute of instrument,School of Information science and engineering,Northeastern University,liaoning,China.Qiao Yunfen is with the Department of Information science and engineering,Northeastern University,liaoning,China

Gas-solid two-phase flow is widely used in the industrial *** is important to know the parameters for the control of *** are three ways to measure the velocity of the flow but the cross-correlation method and spatial filtering menthod are commonly used in the velocity measurements,so this article summarizes the fundamental principles of the two methods and their advantages and *** the future developments of the velocity measurements are included.

关键词： Gas-solid flow Cross-correlation Spatial filtering

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Study of a Novel Algorithm on ADCP System