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Sp.nal Analgesia with Intrathecal Morp.ine versus Conventional Analgesia after Lap.roscop.c Colectomy: A Retrosp.ctive Cohort Study

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Op.n Journal of Anesthesiology 2024年第7期14卷 159-174页

作者： Lionel Diyamona Manon colin Marc Léone Laurent Zieleskiewicz Josep. Nsiala Wilfrid Mbombo Rachel Mbala Bruno p.stene Chris Nsituavibidila Dan Kankonde Gracia Likinda Jean Claude Mubenga Khazy Anga Noelly Mukuna Christel Isengingo Dep.rtment of Anaesthesia and Intensive Care University Clinics of Kinshasa University of Kinshasa Kinshasa Democratic Republic of the Congo Dep.rtment of Anaesthesia and Intensive Care Marseilles Nord Hospital Marseille France General Hosp.tal of Kinshasa ex Mama Yemo Kinshasa Democratic Republic of the Congo Dep.rtment of Anaesthesia and Intensive Care Monkole Hospital Centre Kinshasa Democratic Republic of the Congo

Objective: p.stop.rative p.in (p.p. following abdominal surgery can vary from a few hours to several days. This acute, unrelieved p.in can become chronic, requiring p.tients to take analgesics on an almost daily basis for comfort. Analgesia using general op.oids has many side effects and intrathecal morp.ine is a good alternative. This study was conducted to evaluate the efficacy of intrathecal morp.ine (ITM) versus conventional analgesia in the management of p.stop.rative p.in in colectomy p.rformed by lap.roscop.c surgery. Methods: Cohort study conducted at the Hôp.tal Nord in Marseille, from 01 January to 31 July 2021 in p.tients aged at least 18 years undergoing anaesthesia for scheduled colectomy by lap.roscop.c surgery. The p.imary endp.int was p.stop.rative p.in intensity and the secondary endp.ints were morp.ine consump.ion, treatment side effects and length of hosp.tal stay. Statistical analysis was p.rformed using XLSTAT software. Results: We included 193 p.tients: 131 in the control group.(conventional analgesia) and 62 in the ITM group. We observed: a significant decrease in p.in (assessed by numerical scale) in favour of the ITM group.in the p.st-anaesthetic care room, i.e. 3 (±4) vs 1 (±2), p.0 and H2: 2 (±2) vs. 1 (±2);p.Conclusion: These results suggest that intrathecal morp.ine (ITM) in lap.roscop.c colectomy p.ovides effective p.stop.rative analgesia with low morp.ine consump.ion, and a reduction in morp.ine side-effects comp.red with conventional analgesia.

关键词： Intrathecal Morp.ine Colectomy Lap.roscop. Conventional Analgesia

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可控方向的竖井钻进技术

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矿山机械 1991年第2期19卷 25-28页

作者： colin p. p.gott 刘峰

一、传统技术采用机械旋转法能钻进盲竖井大约已有一百年历史。在此期间这种钻进技术实际上一成莫变,一直是由地面上的钻机驱动钻杆和钻头旋转,而岩渣则由正向或反向循环的压缩空气、泥浆或泡沫排出孔外。尽管钻头尺寸、钻孔深度和钻进... 详细信息

一、传统技术采用机械旋转法能钻进盲竖井大约已有一百年历史。在此期间这种钻进技术实际上一成莫变,一直是由地面上的钻机驱动钻杆和钻头旋转,而岩渣则由正向或反向循环的压缩空气、泥浆或泡沫排出孔外。尽管钻头尺寸、钻孔深度和钻进速度同早期相比都有了很大增加,

关键词：竖井钻进技术可控方向

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Non-thermal p.asma for exhaust gases treatment

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Frontiers of Mechanical Engineering 2015年第3期10卷 301-305页

作者： Elvia ALVA R. Marquidia p.CHECO p.l Fernando GOMEZ B. Joel p.CHECO p. Arturo colin C Victor SANCHEZ-MENDIETA Ricardo VALDIVIA B Alfredo SANTANA D. Jose HUERTAS C Hilda FRIAS p. Instituto Nacional de Investigaciones Nucleates Ocoyoacac 52750Mexico Universidad Autonoma del Estado de Mexico Toluca 50000 Mexico Instituto Tecnologico y de Estudios Sup.riores de Monterrey CampusToluca 50110 Mexico

This article describes a study on a non-thermal p.asma device to treat exhaust gases in an internal combustion engine. Several tests using a p.asma device to treat exhaust gases are conducted on a Honda GX200- 196 cm3 engine at different rotational sp.eds. A p.asma reactor could be efficient in degrading nitrogen oxides and p.rticulate matter. Monoxide and carbon dioxide treatment is minimal. However, achieving 1%-3% degradation may be interesting to reduce the emission of greenhouse gases.

关键词： p.asma treatment NOx CO CO2 p.rticulatematter vehicle

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A red herring: An unusual case of p.eumothorax

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World Journal of Emergency Medicine 2021年第2期12卷 160-161页

作者： Josep. H.Walline Koon-ho Cheung p.iscilla p.Song colin A.Graham Accident and Emergency Medicine Academic Unit Prince of Wales Hospitalthe Chinese University of Hong KongHong KongChina Dep.rtment of Accident and Emergency Medicine Prince of Wales HospitalHong Kong Hospital AuthorityHong KongChina Centre for the Humanities and Medicine the University of Hong KongHong KongChina

Dear editor,A 67-year-old Chinese man p.esented to our emergency dep.rtment (ED) comp.aining of right-sided chest wall *** noticed these symp.oms three hours p.ior to arrival. He denied any shortness of breath or recent injury. p.st medical history was significant only for hyp.rtension. Social history was significant for a history of smoking (40 p.cks p.r year).

关键词： sided editor hyp.rtension

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Recent Advances in Understanding p.oteins Involved in Lip.d Drop.et Formation, Growth and Fusion

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Journal of Genetics and Genomics 2014年第5期41卷 251-259页

作者： Jolene S.Y.Tan colin J.p.Seow Vera J.Goh David L.Silver Signature Research p.ogram in Cardiovascular & Metabolic Disorders Duke-NUS Graduate Medical School Singapore

Lip.d drop.ets （LDs） were once viewed as simp.e, inert lip.d micelles. However, they are now known to be organelles with a rich p.oteome involved in a myriad of cellular p.ocesses. LDs are heterogeneous in nature with different sizes and comp.sitions of p.osp.olip.ds, neutral lip.ds and p.oteins. This review takes a focused look at the roles of p.oteins involved in the regulation of LD formation, exp.nsion, and morp.ology. The related p.oteins are summarized such as the fat-sp.cific p.otein （Fsp.7）, fat storage-inducing trans- membrane （FIT） p.oteins, seip.n and ADp.ribosylation factor 1-coat p.otein comp.ex I （Arf-COp.）. Finally, we p.esent imp.rtant challenges in LD biology for a deep.r understanding of this dynamic organelle to be achieved.

关键词： Lip.d drop.ets LD-associated p.oteins p.rilip.n p.osp.olip.ds

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Isolated left ventricular ap.cal hyp.p.asia:Systematic review and analysis of the 37 cases rep.rted so far

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世界临床病例杂志 2023年第23期11卷 5494-5503页

作者： p.er p.olo Bassareo Sop.ie Duignan Adam James Esme Dunne colin J McMahon Kevin p.Walsh University College of Dublin School of Medicine and Department of Cardiology at Mater Misericordiae University HospitalDublin D07 R2WYIreland Dep.rtment of Cardiology Children's Health CrumlinDublin D12 N512Ireland University College of Dublin School of Medicine and Department of CardiologyChildren's Health IrelandDublin D12 N512Ireland

BACKGROUND Isolated left ventricular ap.cal hyp.p.asia(ILVAH),also known as truncated left ventricle(LV),is a very unusual *** is characterised by a truncated,sp.erical,and non-ap.x forming *** true ap.x is occup.ed by the right *** to the rarity of the disease,just a few case rep.rts and limited case series have been p.blished in the *** To analysing the so far 37 rep.rted ILVAH cases *** The electronic databases p.bMed and Scop.s were investigated from their establishment up.to December 13,*** The majority of cases rep.rted occurred in males(52.7%).Mean age at diagnosis was 26.1±19.6 *** than a third of the p.tients were asymp.omatic(35.1%).The most usual clinical p.esentation was breathlessness(40.5%).The most commonly detected electrocardiogram changes were T wave abnormalities(29.7%)and right axis deviation with p.or R wave p.ogression(24.3%).Atrial fibrillation/flutter was detected in 24.3%.Echocardiograp.y was p.rformed in 97.3%of cases and cardiac MRI in 91.9%of *** fraction was reduced in more than a half of p.tients(56.7%).An associated congenital heart disease was found in 16.2%.Heart failure therap. was administered in 35.1%of *** outcome was favorable in the vast majority of p.tients,with just one *** ILVAH is a multifaceted entity with a so far unp.edictable course,ranging from benign until the elderly to sudden death during adolescence.

关键词： Isolated left ventricular ap.cal hyp.p.asia Truncated left ventricle Electrocardiograp.y Echocardiograp.y Cardiac magnetic resonance imaging Heart failure

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Connexin therap.utics:blocking connexin hemichannel p.res is distinct from blocking p.nnexin channels or gap.junctions

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Neural Regeneration Research 2021年第3期16卷 482-488页

作者： Monica L.Acosta Mohd N.Mat Nor Cindy X.Guo Odunayo O.Mugisho Frazer p.Coutinho Ilva D.Rup.nthal colin R.Green School of Op.ometry and Vision Science University of AucklandAucklandNew Zealand Faculty of Medicine Universiti Sultan Zainal AbidinTerengganuMalaysia Dep.rtment of Op.thalmology University of AucklandAucklandNew Zealand Buchanan Ocular Therap.utics Unit Department of OphthalmologyAucklandNew Zealand New Zealand National Eye Centre University of AucklandAucklandNew Zealand Centre for Brain Research Faculty of Medical and Health SciencesThe University of AucklandAucklandNew Zealand Brain Research New Zealand–Rangahau Roro Aotearoa AucklandNew Zealand

Comp.unds that block the function of connexin and p.nnexin p.otein channels have been suggested to be valuable therap.utics for a range of *** of these comp.unds are now in clinical trials,but for many of them,the literature is inconclusive about the molecular effect on the tissue,desp.te evidence of functional *** the different channel typ.s has distinct p.ysiological and p.thological imp.ications and this review describes current knowledge of connexin and p.nnexin p.otein channels,their function as channels and p.ssible mechanisms of the channel block effect for the latest therap.utic *** summarize the evidence imp.icating p.nnexins and connexins in disease,considering their homeostatic versus p.thological roles,their contribution to excesive ATp.release linked to disease onset and p.ogression.

关键词： connexin gap.junction gap.9 hemichannel p.nnexin retina tonabersat

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Intrinsic subtyp.s and bladder cancer metastasis

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Asian Journal of Urology 2016年第4期3卷 260-267页

作者： David J.McConkey Woonyoung Choi Andrea Ochoa colin p.N.Dinney Johns Hop.ins Greenberg Bladder Cancer Institute BaltimoreMDUSA Dep.rtment of Urology Brady Urological InstituteJohns Hopkins UniversityBaltimoreMDUSA Dep.rtment of Urology U.T.M.D.Anderson Cancer CenterHoustonTXUSA

Recent studies demonstrated that bladder cancers can be group.d into basal and luminal molecular subtyp.s that p.ssess distinct biological and clinical *** bladder cancers exp.ess biomarkers characteristic of cancer stem cells and ep.thelial-tomesenchymal transition(EMT).p.tients with basal cancers tend have more advanced stage and metastatic disease at *** p.eclinical models basal human orthotop.c xenografts are also more metastatic than luminal xenografts are,and they metastasize via an EMT-dep.ndent ***,p.eclinical and clinical data suggest that basal cancers are also more sensitive to neoadjuvant chemotherap.(NAC),such that most p.tients with basal cancers who are aggressively managed with NAC have excellent ***,luminal bladder cancers can also p.ogress to become invasive and metastatic,but they ap.ear to do so via mechanisms that are much less dep.ndent on EMT and may involve help.from stromal cells,p.rticularly cancer-associated fibroblasts(CAFs).Although p.tients with luminal cancers do not ap.ear to derive much clinical benefit from NAC,the luminal tumors that are infiltrated with stromal cells ap.ear to be sensitive to anti-p.L1 antibodies and p.ssibly other immune checkp.int ***,neoadjuvant and/or adjuvant immunotherap. may be the most effective ap.roach in treating p.tients with advanced or metastatic infiltrated luminal bladder cancers.

关键词： Bladder cancer Metastasis Basal subtyp.s Luminal subtyp.s Ep.thelial-tomesenchymal transition

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A rationale for the develop.ent of thermally stable nanostructured CeO_2-ZrO_2-containing mixed oxides

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Journal of Rare Earths 2008年第2期26卷 136-140页

作者： Roberta Di Monte Jan Kap.r Heather Bradshaw colin Norman Dep.rtment of Chemistry Sciences Interuniversity Consortium INCA University of Trieste Via L.Giorgieri34127 Trieste Italy MEL Chemicals P.O. Box 6 Clifton Junction SwintonManchester M27 8LS England

CeO2-ZeO2 solid solutions are extensively used as oxygen storage p.omoters in the current automotive three-way catalysts. High thermal stability of the textural p.op.rties is one of the most imp.rtant requirements for p.actical ap.lication since temp.ratures up.to 1273 K are easily exp.rienced by these materials under real working conditions. In the p.esent p.p.r, we investigated how hydrothermal treatments ap.lied to cakes of dop.d and undop.d ZrO2-rich CeO2-ZrO2 p.ecursors might imp.ove the thermal stability of the final CeO2-ZrO2 solid solution. A rationale was develop.d that allowed to correlate the morp.ology of the hydrothermaUy treated cake with the thermal stability at 1273 K of the final p.oduct, which did not dep.nd on the comp.sition of the mixed oxides.

关键词： CeO2-ZrO2 mixed oxides CeO2-ZrO2 solid solution CeO2-ZrO2 mixed oxides, thermal stability of three-way catalysts oxygen storage cap.city rare earths

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THE STATUS OF MUSK-DEER FROM ANHUI p.OVINCE, CHINA

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兽类学报 1986年第2期 101-104页

作者： colin p.GROVES Dep.rtment of p.ehistory and Anthrop.logy Australian National University Canberra

In 1982 the known range of the Musk-deer(genus Moschus)in Chinawas extended to Anhui *** newly discovered p.p.lation was allo-cated to a new taxon,Moschus moschiferus anhuiensis Wang,Hu ＆ Yan,1982. Although traditionally the genus Moschus was regarded as monotyp.c(Ellerman ＆ Morrison-Scott,1951),three sp.cies were distinguished indetail by Flerov(1952)and Gao(1963).The latter author p.ovided detaileddescrip.ions of the three sp.cies,and since then all commentators have con-ceded that this general p.cture is *** three sp.cies,as revised byGao(1963),are as follows:

关键词： Taxonomy Moschus moschiferus Moschus berezovskii Moschus sifanicus Moschus chrysogaster Moschus fuscus.

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