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International Journal of Sediment Research 2021年第2期36卷 279-290页

作者： Xiaohui Yan colin David Rennie Abdolmajid Mohammadian Department of Civil Engineering University of Ottawa

This paper presents a model for local scour at submerged weirs with downstream slopes that uses a coupled moving-mesh and masked-element approach. In the developed model, the fluid-sediment interface is tracked using a moving-mesh technique, and the effects of the structure on the hydrodynamics and bed morphology are resolved using a masked-element technique. Compared to traditional sediment scour models, based on the moving-mesh technique, the present model has the advantage of allowing for a simpler setup of the computational grids and a larger-amplitude deformation. Laboratory experiments on local scour at a submerged weir with a downstream slope were conducted, which provided bed profiles at different time instants. The results obtained by the present model are compared to the experimental data. The comparisons demonstrate the performance of the model in satisfactorily predicting local scour at a submerged weir with a downstream slope. The model was further modified and employed to carry out additional computations to investigate the influence of various parameters and sub-models.

关键词： numerical modeling Bed morphology Submerged weir Downstream slope Moving-mesh and masked-element OpenFOAM

Lithium sulfide nanocrystals as cathode materials for advanced batteries

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Journal of Energy Chemistry 2021年第12期30卷 138-169,I0004页

作者： Fengming Wan Liran Fang Xin Zhang colin A.Wolden Yongan Yang Institute of Molecular Plus Tianjin UniversityTianjin 300072China Department of Chemical and Biological Engineering Colorado School of Mines1613 Illinois StreetGoldenCO 80401United States

The ever-increasing need for sustainable development requires advanced battery techniques beyond the current generation of lithium ion *** all candidates being explored,lithium-sulfur batteries are a very promising system to be commercialized in the near *** this end,the development of lithium sulfide(Li_(2)S)nanocrystal-based cathodes has received tremendous effort and witnessed multiple *** from the focus on performance improvement in previous reviews,this review summarizes the research progress in line with the approaches of materials synthesis and electrode *** key chemistry,operation procedure,materials characterizations and performance assessments are all given a balanced ***,all approaches are collectively analyzed along the lines of six criteria towards practical applications,i.e.,electrode performance,materials quality,resources sustainability,production cost,operation procedure,and consumed ***,some perspective viewpoints on the future research directions are offered.

关键词： Lithium sulfide nanocrystals Cathode materials Advanced batteries

Ethambutol induced toxic optic neuropathy in HIV positive patients

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International Journal of Ophthalmology(English edition) 2013年第4期6卷 542-545页

作者： Hamzah Mustak Graeme Rogers colin Cook Division of Ophthalmology Groote Schuur Hospital

AIMTo determine whether HIV and the use of antiretroviral therapy is a risk factor for the development of ethambutol toxic optic neuropathy. To describe the clinical course of ethambutol toxic optic neuropathy in pati... 详细信息

关键词： ethambutol HIV toxic optic neuropathy

Participation in cooperative prey capture and the benefits gained from it are associated with individual personality

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Current Zoology 2017年第5期63卷 561-567页

作者： James L.L. LICHTEnSTEIn colin M. WRIGHT Lauren P. LUSCUSKIE Graham A. MOnTGOMERY PInTER-WOLLMAn Jonathan n. PRUITT Department of Biological Sciences University of Pittsburgh Pittsburgh PA 15260 USA Department of Ecology and Evolutionary Biology University of California Los Angeles CA 90095 USA Department of Ecology Evolution and Marine Biology University of California Santa Barbara Santa Barbara CA 93106 USA

In animal societies, behavioral idiosyncrasies of the individuals often guide which tasks theyshould perform. Such personality-specific task participation can increase individual task efficiency,thereby improving group performance. While several recent studies have documented group-levelbenefits of within-group behavioral （i.e., personality） diversity, how these benefits are realized atthe individual level is unclear. Here we probe the individual-level benefits of personality-driven taskparticipation in the social spider Stegodyphus dumicola. In S. dumicola, the presence of at leastone highly bold individual catalyzes foraging behavior in shy colony members, and all group con-stituents heavily compete for prey. We assessed boldness by examining how quickly spidersresumed normal movement after a simulated predator attack. We test here whether （1） participantsin collective foraging gain more mass from prey items and （2） whether bold individuals are less re-sistant to starvation than shy spiders, which would motivate the bold individuals to forage ***, we assembled colonies of shy spiders with and without a bold individual, added one preyitem, and then tracked the mass gain of each individual spider after this single feeding event. Wefound that spiders that participated in prey capture （whether bold or shy） gained more mass thannonparticipators, and colonies containing a single bold spider gained more total mass than purelyshy colonies. We also found that bold spiders participated in more collective foraging events andwere more susceptible to starvation than shy spiders, suggesting that the aggressive foraging ofbold individuals may represent a strategy to offset starvation risk. These findings add to the bodyof evidence that animal personality can shape social organization, individual performance, andgroup success.

关键词： animal personality, keystone individuals, social behaviour, task allocation.

Subspecies in Przewalski's gazelle Procapra przewalskii and its conservation implication

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Chinese Science Bulletin 2013年第16期58卷 1897-1905页

作者： MARDAn Turghan JIAnG ZhiGang GROVES colin P YAnG Ji FAnG HongXia Key Laboratory of Animal Ecology and Conservation Biology Institute of Zoology Chinese Academy of Sciences Key Laboratory of Biogeography and Bioresource in Arid Land Xinjiang Institute of Ecology and Geography Chinese Academy of Sciences Graduate School of Chinese Academy of Sciences Department of Archaeology and Anthropology Australian National University

Przewalski’s gazelle Procapra przewalskii is an endangered species endemic to China. A question remains about subspecific variation in this species. Skulls of Przewalski’s gazelle collected from its current remnant ranges around the Qinghai Lake in combination with those collected prior to the 20th century were measured and analyzed using Hierarchical Cluster Analysis in order to clarify the question. Unexpectedly, P. p. diversicornis, extirpated from its historic range, has spread to the Qinghai Lake region where it has replaced nominotypical P. p. przewalskii and is now restricted to a few small isolated populations around the lake. We discuss the causes of this unexpected replacement. In this study, we discuss the possibility of a new form, possibly a new subspecies, in the Guide Basin, adjacent to Qinghai Lake; it is unclear whether the new form has long existed and was only discovered in recent years, or whether it evolved in recent times due to the geographical isolation and anthropogenic landscape features. The study sheds light on the processes of microevolution and subspeciation in Procapra przewalskii, and based on the findings, we propose measures for conservation strategies for Przewalski’s gazelle.

关键词：普氏原羚亚种保护青海湖地区濒危物种聚类分析普氏野马贵德盆地

A rationale for the development of thermally stable nanostructured CeO_2-ZrO_2-containing mixed oxides

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Journal of Rare Earths 2008年第2期26卷 136-140页

作者： Roberta Di Monte Jan Kapar Heather Bradshaw colin norman Department of Chemistry Sciences Interuniversity Consortium INCA University of Trieste Via L.Giorgieri34127 Trieste Italy MEL Chemicals P.O. Box 6 Clifton Junction SwintonManchester M27 8LS England

CeO2-ZeO2 solid solutions are extensively used as oxygen storage promoters in the current automotive three-way catalysts. High thermal stability of the textural properties is one of the most important requirements for practical application since temperatures up to 1273 K are easily experienced by these materials under real working conditions. In the present paper, we investigated how hydrothermal treatments applied to cakes of doped and undoped ZrO2-rich CeO2-ZrO2 precursors might improve the thermal stability of the final CeO2-ZrO2 solid solution. A rationale was developed that allowed to correlate the morphology of the hydrothermaUy treated cake with the thermal stability at 1273 K of the final product, which did not depend on the composition of the mixed oxides.

关键词： CeO2-ZrO2 mixed oxides CeO2-ZrO2 solid solution CeO2-ZrO2 mixed oxides, thermal stability of three-way catalysts oxygen storage capacity rare earths

Progress and challenges in CRISPR-mediated therapeutic genome editing for monogenic diseases

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The Journal of Biomedical Research 2021年第2期35卷 148-162页

作者： colin T.Konishi Chengzu Long Leon H.Charney Division of Cardiology New York University Grossman School of MedicineNew YorkNY 10016USA Helen and Martin Kimmel Center for Stem Cell Biology New York University Grossman School of MedicineNew YorkNY 10016USA Department of neurology New York University Grossman School of MedicineNew YorkNY 10016USA Department of neuroscience and Physiology New York University Grossman School of MedicineNew YorkNY 10016USA

There are an estimated 10000 monogenic diseases affecting tens of millions of individuals *** application of CRISPR/Cas genome editing tools to treat monogenic diseases is an emerging strategy with the potential to generate personalized treatment approaches for these ***/Cas-based systems are programmable and sequence-specific genome editing tools with the capacity to generate base pair resolution manipulations to DnA or *** complexity of genomic insults resulting in heritable disease requires patientspecific genome editing strategies with consideration of DnA repair pathways,and CRISPR/Cas systems of different types,species,and those with additional enzymatic capacity and/or delivery *** this review we aim to discuss broad and multifaceted therapeutic applications of CRISPR/Cas gene editing systems including in harnessing of homology directed repair,non-homologous end joining,microhomology-mediated end joining,and base editing to permanently correct diverse monogenic diseases.

关键词： gene editing CRISPR-associated protein 9 CRISPR-Cas system genetic disease medical genetics genetic therapy

Advanced optical microscopy methods for in vivo imaging of sub-cellular structures in thick biological tissuesl

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Journal of Innovative Optical Health Sciences 2014年第5期7卷 64-90页

作者： nanguang Chen Shakil Rehman colin J.R.Sheppard Department of Biomedical Engineering national University of Singapore Singapore 117576 Singapore-MIT Alliance for Research and Technology(SMART)Centre Singapore 138602 Department of nanophysics Istituto Italiano di Tecnologia via Morego 3016163 GenovaItaly

Optical microscopy has become an indispensable tool for visualizing sub-cellular structures andbiological ***,scattering in biological tissues is a major obstacle that preventshigh-resolution images from being obtained from deep regions of *** review commontechniques,such as multiphoton microscopy(MPM)and optical coherence microscopy(OCM),for diffraction limited imaging beyond an imaging depth of 0.5 *** implementations havebeen emerging in recent years giving higher imaging speed,deeper penetration,and better *** modulation microscopy(FMM)is a novel method that combines confocal spatialfltering with focal modulation to reject out-of-focus *** has demonstrated animaging depth comparable to those of MPM and OCM,near-real-time image acquisition,and thecapability for multiple contrast mechanisms.

关键词： Confocal microscopy multiphoton microscopy(MPM) optical gating optical coherence tomography(OCT) optical coherence microscopy(OCM) focal modulation microscopy(FMM).

Study of Wildebeest Foraging Processes Using Advection Diffusion Equation: Case of the Serengeti Ecosystem in Tanzania

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Journal of Applied Mathematics and Physics 2023年第11期11卷 3377-3392页

作者： Linus n. Kisoma Torney colin Department of Mathematics and Statistics Sokoine University of Agriculture Morogoro Tanzania Department of Mathematics and Statistics University of Glasgow Glasgow UK

We studied the foraging processes of wildebeest using an advection-diffusion equation. We equipped the model with data collected between 1999 and 2007 from the Serengeti ecosystem from 18 GPS-collared wildebeest. Results analysis show that wildebeest foraging behavior can be explained by advective and diffusive parameters in a heterogeneous habitat like the Serengeti ecosystem.

关键词： Advection-Diffusion Movement Foraging Random Walk

Low Cost 1D DCT Core for Multiple Video Codec

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Chinese Journal of Electronics 2016年第6期25卷 1052-1057页

作者： JIA Rui CHEn Rui LIn colin Yu GUO Zhenhong YAnG Haigang Institute of Electronics Chinese Academy of Sciences The University of Chinese Academy of Sciences

The expandability of high demands for multimedia applications brings out more and more video standards for improving the coding and compression efficiency. As the most commonly used transform, Discrete cosine transform(DCT) achieves excellent energy compaction property and good compression efficiency. Hardware sharing is the mostly used efficient strategy to reduce the cost for video codec. Based on traditional matrix factorization, this paper makes three observations to direct the design of proposed hardware sharing architecture. The proposed architecture can be generally used to compute 8×8 DCT of AVS, H.264, VC-1 and HEVC in a low cost way, and can be used to decode Full-HD and WQXGA formate video sequences in real time. The design has been synthesized in 0.13μm technology. The synthesis results show that the proposed architecture achieves76.9% reduction in gate count, 85.6% decrease in power consumption and 35% improvement in operational speed in comparison with other existing designs.

关键词： Discrete cosine transform(DCT) 8×8 integer transform AVS H.264 VC-1 HEVC Hardware sharing