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世界核心医学期刊文摘（妇产科学分册） 2005年第9期1卷 39-40页

作者： cleland j. Ali M.M. 宁亮 Centre for Population Studies London S ch. of Hyg. and Trop. Med. 49-51 Bedford Square London WC1B 3DP United Kingdom Prof.

OBj.CTIVE: To ascertain the contribution of contraceptive failure to uninten de d births and fetal loss in developing countries. METHODS: Nationally representat ive survey data from married women in 19 developing countries were analyzed. All surveys contained retrospective monthly calendars of contraceptive use and preg nancies for a 5-year period preceding each survey. Information on the intendedn ess of live births, ascertained earlier in the interview, were linked to the cal endar data. Single-decrement life table analysis was applied to episodes of use to estimate failure probabilities. The reproductive consequences of failure wer e established by simple tabulation. Logistic regression was used to explore the determinants of fetal loss. RESULTS: Reported contraceptive failure rates were s imilar to those derived from studies conducted mainly in the United States. Abou t three fourths of pregnancies resulting from contraceptive failure were carried to term, and all but 16%of those were classified by the mother as unwanted or mistimed. j.st over one tenth ended in fetal loss, either induced or spontaneous . Analysis of determinants of fetal loss suggested that a large proportion were induced. The median contribution of failure to all unintended births for all 19 surveys was about 15%, and the contribution to fetal loss was 12%. CONCLUSION: The contribution of contraceptive failure in developing countries is much lower than the estimate of 50%in the United States. Despite the substantial increase s in contraceptive practice that have occurred in Asia, Latin America, the Middl e East, and to a lesser extent, Africa, the level of use is still below the 75% mark achieved in most industrialized countries. Nonuse of contraception remains the dominant direct cause of unintended births, and family planning promotion sh ould remain a public health priority.

关键词：胎儿流产避孕措施已婚女性非意愿妊娠足月分娩活产量表分妊娠情况调查数据析评

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心脏再同步化治疗对心衰患者发病率和死亡率的影响

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世界核心医学期刊文摘（心脏病学分册） 2005年第10期1卷 28-29页

作者： cleland j. G. F. Daubert j.-C. Erdmann E. 宁宁 Department of Cardiology Castle Hill Hospital University of Hull Kingston-upon-Hull United Kingdom

Cardiac Resynchronization reduces symptoms and improves left ventricular function in many patients with heart failure due to left ventricular systolic dysfunction and cardiac dyssynchrony. We evaluated its effects on morbidity and mortality. METHODS: Patients with New York Heart Association class IEt or IV heart failure due to left ventricular systolic dysfunction and cardiac dyssynchrony who were receiving standard pharmacologic therapy were randomly assigned to receive medical therapy alone or with cardiac Resynchronization. The primary end point was the time to death from any cause or an unplanned hospitalization for a maj.r cardiovascular event The principal secondary end point was death from any cause. RESULTS: A total of 813 patients were enrolled and followed for a mean of 29.4 months. The primary end point was reached by 159 patients in the cardiac-Resynchronization group, as compared with 224 patients in the medical-therapy group(39 percent vs. 55 percent; hazard ratio, 0.63; 95 percent confidence interval, 0.51 to 0.77; Pj.t; increased the left ventricular ej.ction fraction; and improved symptoms and the quality of life(P< 0.01 for all comparisons). CONCLUSIONS: In patients with heart failure and cardiac dyssynchrony, cardiac Resynchronization improves symptoms and the quality of life and reduces complications and the risk of death. These benefits are in addition to those afforded by standard pharmacologic therapy. The implantation of a cardiac-Resynchronization device should routinely be considered in such patients.

关键词：心脏再同步化患者发病率心脏协会次要终点左室收缩功能心血管事件射血分数全因死亡左心室功能死亡风险

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Strengthening an in-service reinforcement concrete bridge with prestressed CFRP bars

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j.urnal of Zhej.ang University-Science A(Applied Physics & Engineering) 2009年第5期10卷 635-644页

作者： Hai-long WANG Wei-liang j.N David j. cleland Ai-hui ZHANG Department of Civil Engineering Zhejiang University Hangzhou 310027 China School of Planning Architecture and Civil Engineering Queen's University Belfast Belfast BT9 5AG UK

Carbon fiber reinforced polymer (CFRP) bars were prestressed for the structural strengthening of 8 T-shaped rein-forced concrete (RC) beams of a 21-year-old bridge in China. The ultimate bearing capacity of the existing bridge after retrofit was discussed on the basis of concrete structures theory. The flexural strengths of RC beams strengthened with CFRP bars were controlled by the failure of concrete in compression and a prestressing method was applied in the retrofit. The field construction processes of strengthening with CFRP bars-including grouting cracks, cutting groove, grouting epoxy and embedding CFRP bars, surface treating, banding with the U-type CFRP sheets, releasing external prestressed steel tendons-were introduced in detail. In order to evaluate the effectiveness of this strengthening method, field tests using vehicles as live load were applied before and after the retrofit. The test results of deflection and concrete strain of the T-shaped beams with and without strengthening show that the capacity of the repaired bridge, including the bending strength and stiffness, is enhanced. The measurements of crack width also indicate that this strengthening method can enhance the durability of bridges. Therefore, the proposed strengthening technology is feasible and effective.

关键词： Carbon fiber reinforced polymer (CFRP) bar Reinforced concrete (RC) bridge Strengthening Construction pro-cedure Field test T-shaped beam

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A rare case of failed healing in previously burned skin after a secondary burns

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Burns & Trauma 2017年第4期5卷 268-271页

作者： Stephen j. Goldie Shaun Parsons Hana Menezes Andrew Ives Heather cleland Victorian Adult Burns Service Alfred Hospital Melbourne Australia Department of Surgery Monash University Melbourne Australia Victorian Adult Burns Service Alfred Hospital Melbourne Australia

Background:Patients presenting with large surface area burns are common in our practice;however, patients with a secondary large burn on pre-existing burn scars and grafts are rare and not reported. Case presentation:We report on an unusual case of a patient sustaining a secondary large burn to areas previously inj.red by a burn from a different mechanism. We discuss the potential implications when managing a case like this and suggest potential biological reasons why the skin may behave differently. Our patient was a 33-year-old man who presented with a 5%TBSA burn on skin scarred by a previous 40%total body surface area (TBSA) burn and skin grafts. Initially assessed as superficial partial thickness in depth, the wounds were treated conservatively with dressings;however, they failed to heal and became infected requiring surgical management. Conclusions:Burns sustained in areas of previous burn scars and grafts may behave differently to normal patterns of healing, requiring more aggressive management and surgical intervention at an early stage.

关键词： Previous burns Burn scar Non-healing

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培哚普利在慢性心力衰竭老年患者中的应用(PEP-CHF)研究

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世界核心医学期刊文摘（心脏病学分册） 2007年第3期3卷 50-51页

作者： cleland j.G.F. Tendera M. Adamus j. 刘少伟 Department of Cardiology University of Hull Castle Hill Hospital Castle Road Kingston upon Hull HU16 5JQ United Kingdom

目的:许多被诊断为心力衰竭的患者既无左室(LV)射血分数降低也无瓣膜疾病。少有在该群体中进行的切实随机对照试验,也没有试验针对有舒张功能不全证据的患者,更无试验显示对患者症状、发病率或死亡率的确切疗效。

关键词：慢性心力衰竭 PEP-CHF 培哚普利射血分数舒张功能不全瓣膜疾病随机对照试验试验针全因

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Venous thromboembolism prophylaxis practice and its association with outcomes in Australia and New Zealand burns patients

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Burns & Trauma 2021年第1期9卷 642-651页

作者： Lincoln M.Tracy Peter A.Cameron Yvonne Singer Arul Earnest Fiona Wood Heather cleland Belinda j.Gabbe School of Public Health and Preventive Medicine Monash University553 St Kilda RoadMelbourneVictoria3004Australia Emergency and Trauma Centre The Alfred HospitalCommercial RoadMelbourneVictoria3004Australia Victorian Adult Burns Service Alfred Hospital55 Commercial RoadMelbourneVictoria3004AustraliaAustralia Registry Sciences Unit Department of Epidemiology and Preventive MedicineMonash University553 St Kilda RoadMelbourneVictoria3004Australia Biostatistics Unit Department of Epidemiology and Preventive MedicineMonash University553 St Kilda RoadMelbourneVictoria3004Australia Burn Inj.ry Research Unit University of Western Australia35 Stirling HighwayPerthWestern Australia6009Australia Health Data Research UK Swansea University Medical SchoolSwansea UniversitySingleton ParkSwanseaUK

Background:Patients with burn inj.ries are considered to have an increased risk of venous thromboembolism(VTE).While untreated VTEs can be fatal,no studies have examined chemoprophylaxis *** study aimed to quantify the variation in prevalence of VTE prophylaxis use in patients in Australian and New Zealand burns units and whether prophylaxis use is associated with in-hospital outcomes following burn ***:Admission data for adult burns patients(aged≥16 years)admitted between 1 j.ly 2016 and 31 December 2018 were extracted from the Burns Registry of Australia and New *** effects logistic regression modelling investigated whether VTE prophylaxis usewas associated with the primary outcome of in-hospital ***:There were 5066 admissions over the study *** these patients,81%(n=3799)with a valid response to the VTE prophylaxis data field received some form of VTE *** of VTE prophylaxis ranged from 48.6%to 94.8%of patients between ***-hospital death was recorded inj.sting for confounders,receiving VTE prophylaxis was associated with a decrease in the adj.sted odds of in-hospital mortality(adj.sted odds ratio=0.21;95%CI,0.07–0.63;p=0.006).Conclusions:Variation in the use of VTE prophylaxis was observed between the units,and prophylaxis use was associated with a decrease in the odds of *** findings provide an opportunity to engage with units to further explore differences in prophylaxis use and develop future best practice guidelines.

关键词： Burn inj.ry Venous thromboembolism Prophylaxis Australia New Zealand

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肺基底部填充术

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中华结核和呼吸杂志 1957年第3期05卷 194-194页

作者： j. K. Clarehrough W. P. cleland, Thorax 苏绍丹(摘) 上海第一医学院系统内科学教研组上海第一医学院内科学基础教研组上海第一医学院临床儿科学教研组

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常规脂蛋白检测和载脂蛋白在心血管病预测中的比较

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中华高血压杂志 2019年第7期27卷 699-699页

作者： Welsh C Celis-Morales CA Brown R Mackay DF Lewsey j.Mark PB Gray SR Ferguson LD Anderson j. Lyall DM cleland j. j.und PS Gill j.MR Pell j. Sattar N Welsh P 刘青(译) 叶鹏(摘、审校) 不详

总胆固醇和高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)测量值对于心血管病风险评估至关重要,但对于其他脂质用于风险预测的效用一直存在争议。该研究纳入来自英国生物银行(Biobank)的无基线心血管病、未服用他汀... 详细信息

总胆固醇和高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)测量值对于心血管病风险评估至关重要,但对于其他脂质用于风险预测的效用一直存在争议。该研究纳入来自英国生物银行(Biobank)的无基线心血管病、未服用他汀类药物、有相关的脂质指标(n=346 686)的受试者。

关键词：心血管病风险预测载脂蛋白高密度脂蛋白胆固醇检测他汀类药物总胆固醇风险评估

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心力衰竭患者的非药物措施与药物治疗依从性:欧洲心力衰竭调查资料

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世界核心医学期刊文摘（心脏病学分册） 2007年第8期3卷 23-23页

作者： Laincak M. cleland j.G.F. Lenzen M.j. 罗亮 Dr.Department of Internal Medicine General Hospital Murska Sobota Murska Sobota Slovenia

对生活方式、饮食、接种疫苗以及治疗的建议是心力衰竭(HF)标准处理的一部分。然而,对于心力衰竭患者是否能够回忆起接受了这样的建议,以及此后是否按照建议执行尚知之甚少。从欧洲心力衰竭调查所纳入的患者中获得关于回忆及依从非药物... 详细信息

对生活方式、饮食、接种疫苗以及治疗的建议是心力衰竭(HF)标准处理的一部分。然而,对于心力衰竭患者是否能够回忆起接受了这样的建议,以及此后是否按照建议执行尚知之甚少。从欧洲心力衰竭调查所纳入的患者中获得关于回忆及依从非药物治疗建议的资料。分析共纳入2331例患者,这些患者均在当次入院期间临床诊断为H F,并在出院12周后接受一次访谈。

关键词：药物治疗依从性调查资料标准处理螺内酯临床诊断 β受体阻断剂脂肪摄入地中海地区建议者

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白细胞介素6在心力衰竭患者中的临床意义

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中华高血压杂志(中英文) 2019年第10期 999-999页

作者： Markousis-Mavrogenis G Tromp j.Ouwerkerk W Devalaraj. M Anker SD cleland j. Dickstein K Filippatos GS van der Harst P Lang CC Metra M Ng LL Ponikowski P Samani Nj.Zannad F Zwinderman AH Hillege HL van Veldhuisen Dj.Kakkar Voors AA van der Meer P 林立超余惠珍朱鹏立

炎症反应是心力衰竭的重要病理过程,但以肿瘤坏死因子(tumour necrosis factor,TNF)α为靶点的治疗方案大多不成功。白细胞介素(interleukin,IL)6作为重要炎症介质之一,很可能成为治疗心力衰竭的潜在新靶点。目前,有关IL-6与心力衰竭临... 详细信息

炎症反应是心力衰竭的重要病理过程,但以肿瘤坏死因子(tumour necrosis factor,TNF)α为靶点的治疗方案大多不成功。白细胞介素(interleukin,IL)6作为重要炎症介质之一,很可能成为治疗心力衰竭的潜在新靶点。目前,有关IL-6与心力衰竭临床特征、预后和其他生物标志物之间相关性的研究不多。本研究旨在探讨它们之间的相关性。方法:慢性心力衰竭个体化治疗的生物学研究(biology study to tailore

关键词：心力衰竭白细胞介素左心室射血分数临床意义

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