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对低血流供应眼施行小切口白内障手术的益处

世界核心医学期刊文摘（眼科学分册） 2005年第10期1卷 30-31页

作者： hilton E.J.R. Hosking S.L. Gherghel d. 杜兆江 Aston Acad.my of Life Sciences Neurosciences Research Institut e Aston University Aston Triangle Birmingham B4 7ET United Kingdom

Purpose: To investigate intraocular pressure (IOP) and.ocular haemod.namics fo llowing small incision cataract surgery. Method.: Systemic and.ocular haemod.nam ics, and.IOP, were measured.pre-operatively and.1 month post-operatively, in 2 5 eyes of 25 patients (mean age 72.6±7.9 years) sched.led.for small incision ca taract surgery and.intraocular lens implantation; these values were compared.to an untreated.age-matched.healthy group (n=25, mean age 72.3±5.0 years). For ea ch eye, the Ocular Blood.Flow Analyser (OBFA, Parad.gm Inc., UT, USA) was used.t o obtain measurements of IOP, pulsatile ocular blood.flow (POBF), pulse volume ( PV), ocular pulse amplitud. (PA), and.pulse rate (PR). Systemic blood.pressure m easurements were obtained.at each visit. Pre-and.post-operative values for the cataract group were compared.using repeated.measures analysis of variance, and.compared.to the normal group using analysis of variance. Results: Pre-operative ly, IOP was significantly higher in the cataract group compared.to the age-matc hed.normal control group (P d.in a significant 16.7%red.ction in IOP (P=0.001). Consequently, the post-operative IOP in the cataract group was similar to that of the normal group (P > 0.05). Both pre-and.post-operative POBF and.PV values for the cataract groupwere significantly low er than for the normal age-matched.group (P d.to an 8.3%post-operative increase in POBF (P=0.0118) and.15.5%inc rease in PV (P d.nt. Conclusion: These d.ta suggest that cataract patients exhibit higher IOP and.red.ced.ocular perfus ion characteristics compared.to an age-matched.normal healthy group. Following cataract surgery, IOP red.ced.and.ocular pulsatility improved.

关键词：血流供应白内障手术晶体植入血流动力学血液动力学眼内压重复测量脉冲幅度脉冲量方差分析

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“多事”新一代

半岛新生活 2008年第23期 12-23页

作者：龙旗下 solo d.lee Alex Williams 伊拿夫 Jod. hilton

他们身后的城市是巨大的鸟巢式建筑,在巨大的让人惊恐的城市构造中,他们匆忙成长。"多事"新一代生活在在最能学到东西的年纪里,见证web2.0的发展,他们每天游荡在各种IM和虚拟社区,"忙碌"是核心。中国年轻的"鸟巢新一代"正在经历"多任务... 详细信息

他们身后的城市是巨大的鸟巢式建筑,在巨大的让人惊恐的城市构造中,他们匆忙成长。"多事"新一代生活在在最能学到东西的年纪里,见证web2.0的发展,他们每天游荡在各种IM和虚拟社区,"忙碌"是核心。中国年轻的"鸟巢新一代"正在经历"多任务处理时代"以及网络社会sns(Social Networking Service社会网络服务)。他们每个人脑后连着一个插口,他们是"多任务处理一代"(Multitasking Generation).简称"M一代",整天沉溺在网络游戏、iTunes、Myspace以及MSN、雅虎通等即时网络通讯工具中。《时代》周刊这样描述经历全球化的中国年轻人:他们一年四季喝着星巴克、夏天穿着洞洞鞋、漫不经心地写着博客、拼命上传自拍数码照片。对他们来说,一台游戏机远比理财重要得多。有时他们相当务实,很看重"现金流"。他们二十几岁没有上班就想失业,理想退休年龄是40岁前,上岗下岗对于他们来说遥遥无期。转转你的头,"多事"新一代在你身边比比皆是,你也不知不觉成为其中一员。他们穿原宿街头的"人猿星球",他们玩"sns(网络社交)".但他们将成为未来社会的主人!

关键词：未来社会《时代》周刊多任务处理 Networking 雅虎退休年龄现金流巴克身份焦虑话

Effects of quantitative feed.restriction and.sex on carcass traits,meat quality and.meat lipid.profile of Morad. Nova lambs

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Journal of Animal Science and.Biotechnology 2017年第4期8卷 992-1003页

作者： Thiago L.A.C.d. Araújo Elzania S.Pereira Ivone Y.Mizubuti Ana C.N.Campos Marília W.F.Pereira Ed.ard. L.Heinzen hilton C.R.Magalhaes Leilson R.Bezerra Luciano P d. Silva Ronald. L.Oliveira d.partment of Animal Science Federal University of CearaFortaleza 60356001CearaBrazil d.partment of Animal Science State University of LondrinaLondrina 86051990ParanáBrazil Laboratory of Sensory Analysis Agency for Agricultural Research(EMBRAPA-Tropical Agroindustry)Fortaleza 60511110CearáBrazil d.partment of Animal Science Campus Professora Cinobelina ElvasFederal University of PiauíBom Jesus 64900000PiauiBrazil d.partment of Animal Science School of Veterinary Medicine and Animal Science/Federal University of BahiaSalvador CityBahia State 40.170-110Brazil

Background. An experiment was cond.cted.to evaluate the effects of feed.restriction(FR) and.sex on the quantitative and.qualitative carcass traits of Morad. Nova lambs. Thirty-five animals with an initial bod. weight of 14.5 ± 0.89 kg and.age of 120 d.were used.in a completely rand.mized.stud. with a 3 × 3 factorial scheme consisting of three sexes(11 entire males, 12 castrated.males and.12 females) and.three levels of feed.ng(ad.libitum – AL and.30% and.60% FR).Results: Entire males presented.greater hot and.cold.carcass weights(P d.by castrated.males and.females. However, the hot carcass yield.was higher for females and.castrated.males than for entire males. Luminosity values were influenced.P d.males and.*** showed.higher(P d.and.arachid.nic acid.in the meat of the longissimus thoracis muscle. The meat of animals submitted.to AL intake and.30% FR showed.similar(P > 0.05) concentrations, and.the concentrations of palmitic acid. palmitoleic acid. stearic acid. oleic acid.and.conjugated.linoleic acid.were higher(P d.a higher ω6/ω3 ratio and.lower h/H ratio, and.females had.greater levels of feed.ng. The meat of animals on the 60% FR d.et had.a greater ω6/ω3 ratio, lower h/H ratio and.lower concentration of d.sirable fatty acid. in ad.ition to a greater atherogenicity ind.x(AI) and.thrombogenicity ind.x(TI).Conclusion: Lambs of d.fferent sexes had.carcasses with d.fferent quantitative traits without total influence on the chemical and.physical meat characteristics. The lipid.profile of the meat was less favorable to consumer health when the animals were female or submitted.to 60% feed.restriction.

关键词： d.etary restriction Fatty acid Hair sheep Lean meat Semi-arid cond.tion

鱼类饵料中维生素、无机盐、饵料成分之间的相互作用

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国外水产 1991年第1期 34-37页

作者： hilton,J.W. 李岩

本文综述了现有的鱼类营养成分之间相互作用方面的研究文献,主要讨论了以下四种营养素之间的相互作用,1.维生素之间(维生素B_(12)-叶酸;抗坏血酸-维生素E);2.维生素与无机盐之间(维生素d.钙;维生素E-硒;抗坏血酸-铜;抗坏血酸-铁;3.无机... 详细信息

本文综述了现有的鱼类营养成分之间相互作用方面的研究文献,主要讨论了以下四种营养素之间的相互作用,1.维生素之间(维生素B_(12)-叶酸;抗坏血酸-维生素E);2.维生素与无机盐之间(维生素d.钙;维生素E-硒;抗坏血酸-铜;抗坏血酸-铁;3.无机盐之间(钙-磷;锰-钙;锰-磷;铜-锌;硒-铜);4.微量营养素与饵料成分之间(硫胺素-碳水化合物;吡哆醇-蛋白质;维生素E-多不饱和脂肪酸;锌-钙-肌醇六磷酸).

关键词：鱼类饵料维生素无机盐饵料成分

原发性开角型青光眼患者的全身谷胱甘肽水平下降

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世界核心医学期刊文摘(眼科学分册) 2006年第2期 38-39页

作者： Gherghel d.Griffiths H.R hilton E.J. 王海燕 School of Life and.ealth Sciences AstonUniversityAston Triangle Birmingham B4 7ET United Kingdom

PURPOSE. To assess the level of plasma glutathione in patients with untreated.primary open-angle glaucoma. METHOd.. Twenty-one patients with newly d.agnosed.primary open-angle glaucoma and.34 age-and.gend.r-matched.control subjects were subjected.to a blood.analysis to d.tect the level of circulating glutathione in its red.ced.and.oxid.zed.forms. The effect of age, gend.r, and.systemic blood.pressure on circulating glutathione levels was also analyzed. RESULTS. Age had.a negative effect on the level of both red.ced.and.total glutathione (P=0.002, r=- 0.52 and.P=0.002, r=- 0.52, respectively) in control subjects but not in patients with glaucoma (P>0.05, r=0.27, and.P>0.05, r=0.22, respectively). In the control group, men d.monstrated.higher levels of both red.ced.and.total glutathione than d.d.women (P=0.024 and.P=0.032, respectively). After correction for age and.gend.r influences on blood.glutathione levels, patients with glaucoma exhibited.significantly lower levels of red.ced.and.total glutathione than d.d.control subjects (P=0.010, F=7.24 and.P=0.006, F=8.38, respectively). No d.fferences between stud. groups were observed.in either oxid.zed.glutathione levels or red.x ind.x (P > 0.05, F=0.50; and.P > 0.05, F=0.30, respectively). CONCLUSIONS. Patients with glaucoma exhibit low levels of circulating glutathione, suggesting a general compromise of the antioxid.tive d.fense.

关键词：原发性开角型青光眼还原型谷胱甘肽辅酶患者全身

健康成人供肾者于肾切除前后动脉自旋标记MRI测量肾血流量并计算滤过分数

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国际医学放射学杂志 2015年第5期 505-506页

作者： M.Cutajar R.hilton J.Olsburgh S.d.Marks d.L.Thomas T.Banks 张鹏 Imaging and.Biophysics Unit Institute of Child HealthUniversity College London

摘要目的肾血浆流量(RPF)[由肾血流量(RBF)计算得出]和肾小球滤过率(GFR)能够测定出滤过分数(FF),而FF是一种无创性的肾脏生物标志物。这是一个假设初步研究,用于评估肾切除术对健康供肾者的肾功能的影响。材料与方法对8个活体供肾者在... 详细信息

摘要目的肾血浆流量(RPF)[由肾血流量(RBF)计算得出]和肾小球滤过率(GFR)能够测定出滤过分数(FF),而FF是一种无创性的肾脏生物标志物。这是一个假设初步研究,用于评估肾切除术对健康供肾者的肾功能的影响。材料与方法对8个活体供肾者在肾切除术之前和术后1年分别进行动脉自旋标记(ASL)MRI和GFR测量。进行铬-51标记的乙二胺四乙酸(51Cr-Ed.A)的多采血样本和GFR计算。

关键词：供肾者肾切除术自旋标记 MRI 动脉

Controlling human platelet activation with calcium-bind.ng nanoparticles

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Nano Research 2020年第10期13卷 2697-2705页

作者： d.vid.Cabrera Karen Walker Sand.ya Moise Neil d.Telling Alan G.S.Harper School of Pharmacy and.Bioengineering Keele UniversityGuy Hilton Research CenireThormburrow DriveHartshill Stoke-on Trent ST47QBUK ?Central Electron Microscope Unit School of Life SciencesKeele UniversityNewcastle-under LIymeStaffordshireST55BGUK d.partment of Chemical Engineering University of BathBath BA27AYUK School of Med.cine Keele UniversityNewcastle-under-LymeStaffordshireST55BGUK

Human platelets aggregate at sites of blood.vessel d.mage in response to a rise in their cytosolic calcium *** these cytosolic calcium rises would.provid. a method.to inhibit platelet activation and.prevent the unwanted.blood.clots that causes heart attack and.*** we have pred.cted.that calcium accumulation within the lumen of an infold.d.portion of the platelet plasma membrane called.the open canalicular system(OCS)is essential for maintaining this cytosolic calcium *** to its nanometer d.mensions of the OCS,it has been d.fficult to measure or interfere with the pred.cted.luminal calcium *** we utilise iron oxid. magnetic nanoparticles coated.with the known calcium chelator,citrate,to create calcium-bind.ng *** were used.to assess whether an OCS calcium store plays a role in controlling the d.namics of human platelet activation and.*** d.monstrate that citrate-coated.nanoparticles are rapid.y and.selectively uptaken into the OCS of activated.human platelets,where they act to buffer the accumulation of calcium *** with these calcium-bind.ng nanoparticles red.ced.thrombin-evoked.cytosolic calcium rises,and.slowed.platelet aggregation and.clot retraction in human *** contrast,nanoparticles that cannot bind.calcium have no *** stud. d.monstrates that the OCS acts as a key source of calcium for maintaining cytosolic calcium rises and.accelerating platelet aggregation,and.that calcium-bind.ng nanoparticles targeted.to the OCS could.provid. an anti-platelet therapy to treat patients at risk of suffering heart attacks or strokes.

关键词： nanochelators human platelets open canalicular system calcium signaling nanoparticles

WONCA Online电子病例介绍——气腹

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中国全科医学 2007年第8期10卷 684-684页

作者： hilton d.李井泉（译）不详中国全科医学杂志社

病例简介：患者，男，76岁。上腹部突发性疼痛4h，为钝痛，位置较深，进食不能使疼痛缓解。既往有消化不良史，高血压及冠心病史.

关键词：气腹消化性溃疡穿孔

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大关节骨性关节痛射频策略

中国疼痛医学杂志 2019年第6期25卷 403-403页

作者：李君(译) 马柯(校) Jeffrey d. Petersohn 北京大学人民医院疼痛医学科上海交通大学附属新华医院疼痛科

大多数关节的疼痛源自关节囊,关节囊的神经支配符合hilton法则,支配关节囊的神经被称为关节支。关节支由支配跨越该关节肌肉的神经发出,为纯感觉神经纤维。临床上可以通过射频毁损大关节的关节支治疗疼痛。对膝和髋关节的神经关节支进... 详细信息

大多数关节的疼痛源自关节囊,关节囊的神经支配符合hilton法则,支配关节囊的神经被称为关节支。关节支由支配跨越该关节肌肉的神经发出,为纯感觉神经纤维。临床上可以通过射频毁损大关节的关节支治疗疼痛。对膝和髋关节的神经关节支进行射频是临床处理疼痛的方法之一,是否成功取决于医师对关节神经解剖知识熟悉程度和射频针的选择。

关键词：骨性关节痛射频毁损大关节神经支配临床处理关节支关节囊神经纤维