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Measuring 3D face deformations from RGB images of expression rehabilitation exercises

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Virtual Reality & Intelligent Hardware 2022年第4期4卷 306-323页

作者： claudio FERRARI Stefano BERRETTI Pietro PALA Alberto Del BIMBO Department of Engineering and Architecture University of ParmaParma 43124Italy Department of Information Engineering University of FlorenceFlorence 50139Italy

Background The accurate(quantitative)analysis of 3D face deformation is a problem of increasing interest in many *** particular,defining a 3D model of the face deformation into a 2D target image to capture local and asymmetric deformations remains a challenge in existing literature.A measure of such local deformations may be a relevant index for monitoring the rehabilitation exercises of patients suffering from Par-kinson’s or Alzheimer’s disease or those recovering from a *** In this paper,a complete framework that allows the construction of a 3D morphable shape model(3DMM)of the face is presented for fitting to a target RGB *** model has the specific characteristic of being based on localized components of *** fitting transformation is performed from 3D to 2D and guided by the correspondence between landmarks detected in the target image and those manually annotated on the average *** fitting also has the distinction of being performed in two steps to disentangle face deformations related to the identity of the target subject from those induced by facial *** The method was experimentally validated using the MICC-3D dataset,which includes 11 *** subject was imaged in one neutral pose and while performing 18 facial actions that deform the face in localized and asymmetric *** each acquisition,3DMM was fit to an RGB frame whereby,from the apex facial action and the neutral frame,the extent of the deformation was *** results indicate that the proposed approach can accurately capture face deformation,even localized and asymmetric *** The proposed framework demonstrated that it is possible to measure deformations of a reconstructed 3D face model to monitor facial actions performed in response to a set of ***,these results were obtained using only RGB targets,without the need for 3D scans captured with costly *** paves the way for the use of the

关键词： 3D morphable face model Sparse and locally coherent 3DMM components Local and asymmetric Face deformations Face rehabilitation Face deformation measure

Photovoltaic-thermal solar-assisted heat pump systems for building applications:Integration and design methods

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Energy and Built Environment 2023年第1期4卷 39-56页

作者： Alessandro Miglioli NiccolòAste claudio Del Pero Fabrizio Leonforte Architecture Built environment and Construction Engineering DepartmentPolitecnico di MilanoVia Ponzio 3120133 Milan Italy

The photovoltaic-thermal collector is one of the most interesting technology for solar energy conversion,com-bining electric and thermal energy production in a single ***-compression heat pump is already considered the most suitable clean technology for buildings thermal energy *** combination of these two technologies in an integrated“photovoltaic-thermal solar-assisted heat pump”(PVT-SAHP)system allows reaching a high fraction of the building thermal needs covered by renewable energy sources and to improve the performances of both the photovoltaic-thermal collector and the heat *** first is cooled down increasing its energy conversion efficiency,while providing low-temperature thermal energy to the second,which benefits from a higher evaporation *** review study presents the state-of-art of photovoltaic-thermal solar-assisted heat pump systems intended to cover thermal energy needs in buildings,with a particular focus on the integration methodologies,the possible configurations,the use of different sources and the design of sub-system *** issues are addressed by much scientific research,to improve the reliability and applicability of this technology,as an option for the building *** study aims to present PVT-SAHP systems in an organic and critical way to propose a useful tool for future research *** in detail,the work highlights the fact that the integration of photovoltaic-thermal collectors as evaporator of the heat pump in direct-expansion systems allows the highest heat recovery and ***,the distinction of the two circuits lead to more reliable,flexible and robust systems,especially when combined with a second heat source,being able to cover both heating and cooling *** implementation of real-time control strategy,as well as the continuous development of the compressor and refrigerant industries is positively influencing this technology,which is receiving more an

关键词： Solar-assisted heat pump Photovoltaic-thermal collector PVT-SAHP Renewable energy HVAC Technology review

A deep neural network based model for the prediction of hybrid electric vehicles carbon dioxide emissions

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Energy and AI 2021年第3期5卷 1-17页

作者： claudio Maino Daniela Misul Alessandro Di Mauro Ezio Spessa IC Engines Advanced Laboratory Dipartimento Energia“Galileo Ferraris”Politecnico di Torinoc.so Duca degli Abruzzi 2410129 TorinoItaly

Hybrid electric vehicles(HEV)are nowadays proving to be one of the most promising technologies for the im-provement of the fuel economy of several transportation *** far as the on-road category is concerned,a wise selection of the powertrain design is needed to exploit the best energetic performance achievable by a *** the methodologies developed for comparing different hybrid architectures,global optimizers have demonstrated the capability of leading to optimal design solutions at the expense of a relevant compu-tational *** the present paper,an innovative deep neural networks-based model for the prediction of tank-to-wheel carbon dioxide emissions as estimated by a Dynamic Programming(DP)algorithm is *** model consists of a pipeline of neural networks aimed at catching the correlations lying between the de-sign parameters of a HEV architecture and the main outcomes of the DP,namely powertrain feasibility and tail pipe CO_(2) ***,an automatic search tool(AST)has been developed for tuning the main hyper-parameters of the *** results have been registered by applying the pipeline to three databases related to three different HEV parallel *** capability of the pipeline has been proved through an extensive testing campaign made up by multiple *** performances above 91%as well as average regression errors below 1%have been achieved during an extensive set of *** presented model could hence be considered as an effective tool for supporting HEV design optimization phases.

关键词： Deep neural networks Carbon dioxide emissions Hybrid electric vehicles Dynamic programming

Dietary supplementation of Rosmarinus officinalis *** in sheep affects the abundance of rumen methanogens and other microbial populations

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Journal of Animal Science and Biotechnology 2016年第4期7卷 514-521页

作者： Gabriella Cobellis Zhongtang Yu claudio Forte Gabriele Acuti Massimo Trabalza-Marinucci Department of Veterinary Medicine University of Perugia Department of Animal Sciences The Ohio State University

Background： Rumen microbiome has a great influence on ruminant health and productivity. Different plant extracts have been tested for their ability to modulate the rumen microbiome to improve feed digestion and fermentation. Among the evaluated plant extracts, essential oils, tannins, and saponins appeared to have positive effects on rumen protein metabolism, volatile fatty acids production, and methane and ammonia production. Methods： The objective of this study was to evaluate the effect of rosemary （Rosmarinus officinalis L.） leaves and essential oils on rumen microbial populations. Four ruminally cannulated sheep were used in a 4x4 Latin square design fed （21 d/period）： 1） a control diet composed of alfalfa hay and concentrate pellet （CTR）, 2） CTR supplemented with 7 g/d/sheep of rosemary essential oil adsorbed on an inert support （EO）, 3） CTR with 10 g/d/sheep of dried and ground rosemary leaves （RL）, and 4） CTR with 10 g/d of dried and ground rosemary leaves pelleted into concentrate （RL pellet）. Abundance of total bacteria, archaea, protozoa, and some select bacterial species or groups was quantified using qPCR, while the community of bacteria and archaea was profiled using denaturing gradient gel electrophoresis. Results： No difference in abundance was noted for total bacteria, protozoa, or Rurninococcus flavefaciens between the control and the treatments, but the rosemary leaves, either in loose form or in pellet, decreased the abundance of archaea and the genus Prevotello （P 〈 0.001）. The rosemary leaves in loose form also decreased （P 〈 0.001） the abundance of Ruminococcus albus and Clostridium aminophilum, while the EO increased （P 〈 0.001） the abundance of Fibrobocter sucdnogenes. The community of bacteria and archaea was not affected by any of the supplements. Conclusions： Being able to affect the abundance of several groups of rumen microbes that are known to be involved in degradation of protein and fiber and production of methane and ammonia, rosema

关键词： Archaea Essential oil Plant extracts Rosemary Rumen microbiome

Distal pancreatectomy in the new era of minimally invasive surgery: the on-going debate on the cost-effectiveness

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Hepatobiliary Surgery and Nutrition 2019年第6期8卷 659-661页

作者： Giuseppe Quero claudio Fiorillo Sergio Alfieri Digestive Surgery Unit Fondazione Policlinico Universitario A.Gemelli IRCCSCRMPG(Advanced Pancreatic Research Center)Largo A.GemelliRomeItaly UniversitàCattolica del Sacro Cuore Largo A.GemelliRomeItaly

We read with great interest the article of Rodriguez et al.,"Which method of distal pancreatectomy is cost-effective among open,laparoscopic,or robotic surgery?"(1).In the current climate of limited hospital sources and control of medical costs,the authors afford the interesting topic of the cost-effectiveness evaluation of the robot-assisted distal pancreatectomy(RDP)in comparison to the laparoscopic(LDP)and open approaches(ODP).To accomplish this purpose,they focused their attention on both the clinical and the economical outcomes of the three different techniques.

关键词： surgery al. cost

Consequences of Helicobacter pylori infection in children

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World Journal of Gastroenterology 2010年第41期16卷 5181-5194页

作者： Lucia Pacifico Caterina Anania John F Osborn Flavia Ferraro claudio Chiesa Department of Pediatrics Sapienza University of Rome 324 I-00161 Rome Italy Department of Public Health Sciences Sapienza University of Rome I-00185 Rome Italy Department of Molecular Medicine National Research Council I-00133 Rome Italy

Although evidence is emerging that the prevalence of Helicobacter pylori (H. pylori) is declining in all age groups, the understanding of its disease spectrum continues to evolve. If untreated, H. pylori infection is lifelong. Although H. pylori typically colonizes the hu-man stomach for many decades without adverse con-sequences, children infected with H. pylori can manifest gastrointestinal diseases. Controversy persists regarding testing (and treating) for H. pylori infection in children with recurrent abdominal pain, chronic idiopathic thrombocytopenia, and poor growth. There is evidence of the role of H. pylori in childhood iron deficiency anemia, but the results are not conclusive. The possibility of an inverse relationship between H. pylori and gastroesophageal reflux disease, as well as childhood asthma, remains a controversial question. A better understanding of the H. pylori disease spectrum in childhood should lead to clearer recommendations about testing for and treating H. pylori infection in children who are more likely to develop clinical sequelae.

关键词： Helicobacter pylori Children Gastrointestinal diseases Epigastric pain Anemia Growth retardation Chronic idiopathic thrombocytopenic pupura

Simultaneous penile prosthesis and male sling/artificia urinary sphincter

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Asian Journal of Andrology 2013年第1期15卷 10-15页

作者： Dominic Lee claudio Romero Frances Alba O Lenaine Westney Run Wang Department of Urology University of Texas MD Anderson Cancer Center Houston TX 77030 USA and Division of Urology University of Texas Medical School at Houston Houston TX 77030 USA

Erectile dysfunction （ED） and stress urinary incontinence （SUI） from urethral sphincteric deficiency is not an uncommon problem. The commonest etiology is intervention for localized prostate cancer and/or radical cystoprostatectomy for muscle invasive bladder cancer. Despite advances in surgical technology with robotic assisted laparoscopic prostatectomy and nerve sparing techniques, the rates of ED and SUI remain relatively unchanged. They both impact greatly on quality of life domains and have been associated with poor performance outcomes. Both the artificial urinary sphincter and penile prosthesis are gold standard treatments with proven efficacy, satisfaction and durability for end-stage SUI and ED respectively. Simultaneous prosthesis implantation for concurrent conditions has been well described, mostly in small retrospective series. The uptake of combination surgery has been slow due in part to technical demands of the surgery and to an extent, a heightened anxiety over potential complications. This paper aims to discuss the technical aspect of concurrent surgery for both disease entity and the current published outcomes of the various surgical techniques with this approach.

关键词： artificial urinary sphincter dual implants erectile dysfunction penile prosthesis stress urinary incontinence

Is osteoporosis risk in anorexia nervosa underestimated? A case report series

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Open Journal of Internal Medicine 2013年第4期3卷 115-118页

作者： Bruno Pacciardi claudio Cargioli Simone Belli Biagio Cotugno Samanta augusto Luca Di Paolo Mauro Mauri Clinical and Experimental Medicine Department (Psychiatry Division) University of Pisa Italy

Introduction: Anorexia nervosa (AN) is a mental disorder whose features are deliberate weight loss, disordered body image, and intrusive overvalued fears of gaining weight. Long-term consequences of AN include endocrine dysfunctions leading to secondary amenorrhea, bone loss and/or osteoporosis with an increased risk of bone fracture. Therefore young women with AN may develop a risk for bone fractures comparable to that of postmenopausal women. Methods: In this case report series Bone Mineral Density (BMD) was examined by Dual energy X-ray Absorptiometry (DXA) in 19 hospitalized patients with diagnosis of AN and prolonged amenorrhea. Results: All patients showed a lumbar/femoral bone loss or osteoporosis, with an increased fracture risk comparable to that of postmenopausal women. Conclusions: Our observation suggests that DXA evaluation of anorexic patients with prolonged amenorrhea would be helpful to prevent fracture risk in this population of patients. However, although DXA is almost routinely recommended in women over 65, it is not in young AN patients with prolonged amenorrhea.

关键词： Anorexia Nervosa Amenorrhea Osteoporosis Fracturerisk DXA BMD

Single-run reversed-phase HPLC method for determining sertraline content,enantiomeric purity,and related substances in drug substance and finished product

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Journal of Pharmaceutical Analysis 2020年第6期10卷 610-616页

作者： Alessia Rosetti Rosella Ferretti Leo Zanitti Adriano Casulli claudio Villani Roberto Cirilli National Centre for the Control and Evaluation of Medicines Chemical Medicines UnitIstituto Superiore di Sanita(ISS)Viale Regina Elena 29900161RomeItaly Department of Chemistry and Technology of Drugs Sapienza University of Rome00185RomeItaly WHO Collaborating Centre for the Epidemiology Detection and Control of Cystic and Alveolar EchinococcosisEuropean Union Reference Laboratory for ParasitesIstituto Superiore di Sanita(ISS)Viale Regina Elena 29900161RomeItaly

A direct enantio-,diastereo-,and chemo-selective high-performance liquid chromatographic method was developed for determining the content,enantiomeric purity,and related substances of the chiral antidepressant drug sertraline HCl in a single chromatographic *** separation was achieved on a chiral stationary phase based on amylose tris(3-chloro-5-methylphenylcarbamate)under reversed-phase *** method was optimized by evaluating the influence of the temperature and mobile phase composition on the retention and *** application of the single-run approach allowed to baseline resolve all investigated species in less than 15 min,without using buffers or tandem-coupled *** chromatographic method was validated according to the guidelines of the Official Medicines Control Laboratory and applied to control the content of sertraline HCl and related chiral substances in a generic antidepressant formulation.

关键词： Chiralpak IG-3 Enantiomers Diastereomers Reversed-phase enantioselective HPLC Sertraline HCl