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Scalability of biomass-derived graphene derivative materials as viable anode electrode for a commercialized microbial fuel cell: A systematic review

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Chinese Journal of Chemical Engineering 2023年第3期55卷 277-292页

作者： Mustapha Omenesa Idris claudia Guerrero-Barajas Hyun-Chul Kim Asim Ali Yaqoob Mohamad Nasir Mohamad Ibrahim School of Chemical Sciences Universiti Sains Malaysia11800 PenangMalaysia Department of Pure and Industrial Chemistry Kogi State UniversityP.M.B 1008 AnyigbaKogi StateNigeria Laboratorio de Biotecnologia Ambiental Departamento de BioprocesosUnidad Profesional Interdisciplinaria de BiotecnologiaInstituto Politecnico NacionalAv.Acueducto s/nCol.Barrio La Laguna Ticoman07340 Mexico CityMexico Research Institute for Advanced Industrial Technology College of Science and TechnologyKorea UniversitySejong 30019Republic of Korea

Microbial fuel cell(MFC) is an advanced bioelectrochemical technique that can utilize biomass materials in the process of simultaneously generating electricity and biodegrading or bio transforming toxic pollutants from wastewater. The overall performance of the system is largely dependent on the efficiency of the anode electrode to enhance electron transportation. Furthermore, the anode electrode has a significant impact on the overall cost of MFC setup. Hence, the need to explore research focused towards developing cost-effective material as anode in MFC. This material must also have favourable properties for electron transportation. Graphene oxide(GO) derivatives and its modification with nanomaterials have been identified as a viable anode material. Herein, we discussed an economically effective strategy for the synthesis of graphene derivatives from waste biomass materials and its subsequent fabrication into anode electrode for MFC applications. This review article offers a promising approach towards replacing commercial graphene materials with biomass-derived graphene derivatives in a view to achieve a sustainable and commercialized MFC.

关键词： Microbial fuel cell Biomass Anode fabrication Catalyst Design Cost-effective performance

Having a Partner and Having Children:Comparisons of Adults with Congenital Heart Disease and the General Population:A 15-Year Case-Control Study

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Congenital Heart Disease 2023年第3期18卷 337-348页

作者： Siegfried Geyer claudia Dellas Thomas Paul Matthias Müller Kambiz Norozi Medical Sociology Unit Hannover Medical SchoolHannover30625Germany Department of Pediatric Cardiology Intensive Care Medicine and NeonatologyUniversity Medical Center GoettingenGoettingenGermany Department of Pediatrics Western UniversityLondonOntarioCanada Department of Pediatric Cardiology and Intensive Care Medicine Hannover Medical SchoolHannoverGermany

Objectives:To examine whether patients with congenital heart disease(CHD)are less likely to have a partner or children than individuals from the general ***:Longitudinal study with two assessments of the same patients(n=244)from a hospital population and controls(n=238)from the German Socio-Economic Panel(GSOEP)using parental education,patients age,and sex as matching *** first patient study was conducted between 5/2003 and 6/2004,the second one between 5/2017 and 4/*** were drawn from GSOEP-surveys 2004 and ***-severity was classified according to type of surgery:curative,reparative,or *** single was used as outcome measure,for offspring the outcome was having children or ***:Among women with CHD the rate of those living single was higher than among controls with the differences depending on disease complexity(curative:OR=5.5;reparative:OR=1.9;palliative:OR=2.7).No statistically significant differences between patients and controls emerged in the male study *** respect to children a marked difference emerged between women with CHD and *** patients the odds of having children were lower than among controls(curative:OR=0.3;reparative:OR=0.3;palliative:OR=0.2).The rate of patients with children with CHD(women:5.6%;men:4.9%)was higher than expected(1%)if compared with the general ***:Using partnership and children as outcome criteria,patients with CHD are disadvantaged if compared to subjects from the general *** female patients the social consequences of the disease turned out as more pervasive than in women.

关键词： Congenital heart disease children partnership panel study case-control study

New epidemiological trends of respiratory syncytial virus bronchiolitis during COVID‑19 pandemic

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World Journal of Pediatrics 2023年第5期19卷 502-504页

作者： Emanuele Castagno Irene Raffaldi Francesco Del Monte Silvia Garazzino claudia Bondone Department of Pediatric Emergency Regina Margherita Children’s Hospital-A.O.U.CittàDella Salute e della Scienza di TorinoPiazza Polonia 9410126 TurinItaly Department of Public Health and Pediatrics University of TurinTurinItaly Pediatric Infectious Disease Unit Regina Margherita Children’s Hospital-A.O.U.Cittàdella Salute e della Scienza di TorinoPiazza Polonia 9410126 TurinItaly

Restrictive measures adopted worldwide against COVID19(e.g.,wearing masks,frequent hand washing,and social distancing)produced not only a decrease in SARS-CoV-2 difusion but also a drastic reduction in respiratory diseases caused by other pathogens,as reported by many authors[1,2].The spread of respiratory viruses,particularly respiratory syncytial virus(RSV),has been completely changed during the winter of 2020–2021[3,4],but an unusual resurgence of RSV infection has been recently reported in diferent countries[3-7].

关键词： respiratory syncytial diseases

Tumor microenvironment involvement in colorectal cancer progression via Wnt/β-catenin pathway:Providing understanding of the complex mechanisms of chemoresistance

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World Journal of Gastroenterology 2022年第26期28卷 3027-3046页

作者： María Belén Novoa Díaz María Julia Martín claudia Gentili Departamento de Biología Bioquímica y FarmaciaUniversidad Nacional del Sur(UNS)-INBIOSUR(CONICET-UNS)Bahía Blanca 8000Argentina Departamento de Química Universidad Nacional del Sur(UNS)-INQUISUR(CONICET-UNS)Bahía Blanca 8000Argentina

Colorectal cancer(CRC)continues to be one of the main causes of death from cancer because patients progress unfavorably due to resistance to current *** of the Wnt/β-catenin pathway plays a fundamental role in the genesis and progression of several types of cancer,including *** many subtypes of CRC,hyperactivation of theβ-catenin pathway is associated with mutations of the adenomatous polyposis coli ***,it can also be associated with other *** recent years,studies of the tumor microenvironment(TME)have demonstrated its importance in the development and progression of *** this tumor nest,several cell types,structures,and biomolecules interact with neoplastic cells to pave the way for the spread of the ***-communications between tumor cells and the TME are then established primarily through paracrine factors,which trigger the activation of numerous signaling *** advances in the field of oncology have been made in the last *** Minireview aims to actualize what is known about the central role of the Wnt/β-catenin pathway in CRC chemoresistance and aggressiveness,focusing on crosscommunication between CRC cells and the *** this analysis,our main objective was to increase the understanding of this complex disease considering a more global *** many treatments for advanced CRC fail due to mechanisms involving chemoresistance,the data here exposed and analyzed are of great interest for the development of novel and effective therapies.

关键词： Colorectal cancer β-catenin pathway Tumor stroma Tumor microenvironment factors Cancer progression Drug resistance

Practical insights into chronic management of hepatic Wilson’s disease

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World Journal of Clinical Cases 2022年第14期10卷 4334-4347页

作者： Erica Nicola Lynch claudia Campani Tommaso Innocenti Gabriele Dragoni Paolo Forte Andrea Galli Gastroenterology Research Unit Department of Experimental and Clinical Biomedical Sciences“Mario Serio”University of FlorenceFlorence 50134Italy Department of Experimental and Clinical Medicine University of FlorenceFlorence 50134Italy Department of Medical Biotechnologies University of SienaSiena 53100Italy Division of Gastroenterology University Hospital“Careggi”Florence 50134Italy

Wilson’s disease(WD)is a rare inherited disorder of human copper metabolism,with an estimated prevalence of 1:30000-1:50000 and a broad spectrum of hepatic and neuropsychiatric *** healthy individuals,the bile is the main route of elimination of *** WD patients,copper accumulates in the liver,it is released into the bloodstream,and is excreted in *** can also be accumulated in the brain,kidneys,heart,and osseous matter and causes damage due to direct toxicity or oxidative *** WD is commonly but not exclusively diagnosed in childhood or young ***,non-cirrhotic WD patients seem to have a normal life ***,chronic management of patients with Wilson’s disease is challenging,as available biochemical tests have many limitations and do not allow a clear identification of non-compliance,overtreatment,or treatment *** provide optimal care,clinicians should have a complete understanding of these limitations and counterbalance them with a thorough clinical *** aim of this review is to provide clinicians with practical tools and suggestions which may answer doubts that can arise during chronic management of patients with hepatic *** particular,it summarises current knowledge on Wilson’s disease clinical and biochemical monitoring and *** also analyses available evidence on pregnancy and the role of low-copper diet in *** research should focus on trying to provide new copper metabolism tests which could help to guide treatment adjustments.

关键词： Wilson’s disease Urinary copper excretion Non-ceruloplasmin-bound copper D-penicillamine Trientine Zinc salts

Location-based prediction model for Crohn’s disease regarding a novel serological marker,anti-chitinase 3-like 1 autoantibodies

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World Journal of Gastroenterology 2023年第42期29卷 5728-5750页

作者： Nora Sipeki Patricia Julianna Kovats claudia Deutschmann Peter Schierack Dirk Roggenbuck Maria Papp Division of Gastroenterology Department of Internal MedicineFaculty of MedicineUniversity of DebrecenDebrecen H-4032Hungary Kálmán Laki Doctoral School Faculty of MedicineUniversity of DebrecenDebrecen H-4032Hungary Institute of Biotechnology Faculty Environment and Natural SciencesBrandenburg University of Technology Cottbus-SenftenbergSenftenberg 01968Germany Faculty of Health Sciences Brandenburg Brandenburg University of Technology Cottbus-SenftenbergSenftenberg 01968Germany Medipan GmbH&GA Generic Assays GmbH Dahlewitz-Berlin 15827Germany

BACKGROUND Defective neutrophil regulation in inflammatory bowel disease(IBD)is thought to play an important role in the onset or manifestation of IBD,as it could lead to damage of the intestinal mucosal barrier by the infiltration of neutrophils in the inflamed mucosa and the accumulation of *** neutrophils in the context of innate immune responses,immunoglobulin A(IgA)as an acquired immune response partakes in the defense of the intestinal *** normal conditions,IgA contributes to the elimination of microbes,but in connection with the loss of tolerance to chitinase 3-like 1(CHI3L1)in IBD,IgA could participate in CHI3L1-mediated improved adhesion and invasion of potentially pathogenic *** tolerance brake to CHI3L1 and the occurrence of IgA autoantibodies to this particular target,the exact role and underlying mechanisms of CHI3L1 in the pathogenesis of IBD are still *** To determine the predictive potential of Ig subtypes of a novel serological marker,anti-CHI3L1 autoantibodies(aCHI3L1)in determining the disease phenotype,therapeutic strategy and long-term disease course in a prospective referral cohort of adult IBD *** Sera of 257 Crohn’s disease(CD)and 180 ulcerative colitis(UC)patients from a tertiary IBD referral center of Hungary(Division of Gastroenterology,Department of Internal Medicine,Faculty of Medicine,University of Debrecen)were assayed for IgG,IgA,and secretory IgA(sIgA)type aCHI3L1 by enzyme-linked immunosorbent assay using recombinant CHI3L1,along with 86 healthy controls(HCONT).RESULTS The IgA type was more prevalent in CD than in UC(29.2%vs 11.1%)or HCONT(2.83%;P<0.0001 for both).However,sIgA subtype aCHI3L1 positivity was higher in both CD and UC patients than in HCONT(39.3%and 32.8%vs 4.65%,respectively;P<0.0001).The presence of both IgA and sIgA aCHI3L1 antibodies was associated with colonic involvement(P<0.0001 and P=0.038,respectively)in patients with *** disease behavior a

关键词： Chitinase 3-like 1 autoantibodies Crohn’s disease Ulcerative colitis Disease progression Immunoglobulin subtypes Enzyme-linked immunosorbent assay

Adult mammalian neurogenesis and motivated behaviors

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Integrative Zoology 2018年第6期13卷 655-672页

作者： claudia JORGENSEN Behavioral Science Department Utah Valley UniversityOremUtahUSA

Adult neurogenesis continues to captivate the curiosity of the scientific community;and researchers seem to have a particular interest in identifying the functional implications of such *** the majority of research focuses on the association between adult neurogenesis and learning and memory(including spatial learning associated with hippocampal neurogenesis and olfactory discrimination associated with neurogenesis in the olfactory system),the following review will explore the link to motivated *** particular,goal-directed behaviors such as sociosexual,parental,aggressive,as well as depression-and anxiety-like behaviors and their reciprocal association to adult neurogenesis will be *** review will detail research in humans and other mammalian ***,the potential mechanisms underlying these neurogenic alterations will be ***,the review will conclude with a discussion on the functional significance of these newly generated cells in mediating goal-directed behaviors.

关键词： adult neurogenesis aggression anxiety depression reproduction

Narrative minireview of the spatial epidemiology of substance use disorder in the United States:Who is at risk and where?

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World Journal of Clinical Cases 2023年第11期11卷 2374-2385页

作者： Diego F Cuadros Adam J Branscum claudia M Moreno Neil J MacKinnon Digital Futures University of CincinnatiCincinnatiOH 45206United States Department of Biostatistics Oregon State UniversityCorvallisOR 97331United States Department of Physiology and Biophysics University of WashingtonSeattleWA 98195United States Department of Population Health Sciences Augusta UniversityAugustaGA 30912United States

Drug overdose is the leading cause of death by injury in the United *** incidence of substance use disorder(SUD)in the United States has increased steadily over the past two decades,becoming a major public health problem for the *** drivers of the SUD epidemic in the United States have changed over time,characterized by an initial heroin outbreak between 1970 and 1999,followed by a painkiller outbreak,and finally by an ongoing synthetic opioid *** nature and sources of these abused substances reveal striking differences in the socioeconomic and behavioral factors that shape the drug ***,the geospatial distribution of the SUD epidemic is not *** United States has specific locations where vulnerable communities at high risk of SUD are concentrated,reaffirming the multifactorial socioeconomic nature of this epidemic.A better understanding of the SUD epidemic under a spatial epidemiology framework is necessary to determine the factors that have shaped its spread and how these patterns can be used to predict new outbreaks and create effective mitigation *** narrative minireview summarizes the current records of the spatial distribution of the SUD epidemic in the United States across different periods,revealing some spatiotemporal patterns that have preceded the occurrence of *** analyzing the epidemic of SUD-related deaths,we also describe the epidemic behavior in areas with high incidence of ***,we describe public health interventions that can be effective for demographic groups,and we discuss future challenges in the study and control of the SUD epidemic in the country.

关键词： Substance use disorder Spatial epidemiology Risk factors Spatial statistics Disease mapping

Tensile strength and damage of open-cell ceramic foams under cylindrical splitting test

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Journal of Advanced Ceramics 2023年第11期12卷 2003-2016页

作者： Yajie Dai Jana Hubálková claudia Voigt Martin Abendroth Xiong Liang Wen Yan Yawei Li Christos G.Aneziris State Key Laboratory of Refractories and Metallurgy Wuhan University of Science and TechnologyWuhan 430081China Institute of Ceramics Refractories and Composite MaterialsTU Bergakademie FreibergFreiberg 09599Germany Institute of Mechanics and Fluid Dynamics TU BergakademieFreibergFreiberg 09599Germany National–provincial Joint Engineering Research Center of High Temperature Materials and Lining Technology Wuhan 430081China

To widen the understanding of tensile failure of reticulated ceramic foams and expand the available mechanical method,a cylindrical splitting test is developed in the present study based on alumina open-cell foams of three different pore *** biaxial method is validated by characterization of mechanical parameters,and the in-situ fracture process is validated by a digital image correlation,followed by a formula correction for effective tensile strength with consideration of discrete crack *** experimental setup curved loading platens,compliant pad and intermediate quasi-static loading rate are proposed for guaranteeing tensile failure under a radial compressive *** strength,fracture energy,and brittleness increase with the foam pore density,and the fracture behavior is a balanced result of materials and foam structural support *** analytical model of splitting tensile strength with structural parameters is derived,which implies its dependence on cell size and critical stress intensity factor of strut materials.

关键词： cylindrical splitting test mechanical behavior structural parameters alumina ceramic foams digital image correlation