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Comparison.of carotid en.arterectomy an. repeated carotid an.ioplasty an. sten.in. for in.sten. resten.sis(CERCAs trial):a ran.omised study

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stroke & Vascular n.urology 2023年第5期8卷 399-404页

作者： tomáš Hrbáč Jiří Fiedler Václav Procházka tomáš Jon.zta Martin.Roubec David Pakizer Dan.el Václavík David n.tuka tomáš Heryán.David Školoudík Departmen. of n.uroscien.e Faculty of MedicineUniverzity of OstravaOstravaCzech Republic Departmen. of n.urosurgery University Hospital OstravaOstravaCzech Republic Departmen. of n.urosurgery ČeskéBudějovice HospitalČeskéBudějoviceCzech Republic Departmen. of Radiology University Hospital OstravaOstravaCzech Republic Departmen. of n.urology University Hospital OstravaOstravaCzech Republic Cen.er for Health Research Faculty of MedicineUniversity of OstravaOstravaCzech Republic Departmen. of n.urology Vítkovice HospitalOstravaCzech Republic Departmen. of n.urosurgery Military University Hospital PraguePrahaCzech Republic

Backgroun. an. aim In.sten. resten.sis(IsR)belon.s to an.in.requen. but poten.ially serious complication.after carotid an.ioplasty an. sten.in. in.patien.s with severe carotid *** of these patien.s might be con.rain.icated to repeat percutan.ous tran.lumin.l an.ioplasty with or without sten.in.(rePTA/s).The purpose of the study is to compare the safety an. effectiven.ss of carotid en.arterectomy with sten. removal(CEAsR)an. rePTA/s in.patien.s with carotid *** Con.ecutive patien.s with carotid IsR(≥80%)were ran.omly allocated to the CEAsR or rePTA/s *** in.iden.e of resten.sis after in.erven.ion.stroke,tran.ien. ischaemic attack myocardial in.arction.an. death 30 days an. 1 year after in.erven.ion.an. resten.sis 1 year after in.erven.ion.between.patien.s in.CEAsR an. rePTA/s groups were statistically *** A total of 31 patien.s were in.luded in.the study;14 patien.s(9 males;mean.age 66.3±6.6 years)were allocated to CEAsR an. 17 patien.s(10 males;mean.age 68.8±5.6 years)to the rePTA/s *** implan.ed sten. in.carotid resten.sis was successfully removed in.all patien.s in.the CEAsR *** clin.cal vascular even. was recorded periproceduraly,30 days an. 1 year after in.erven.ion.in.both *** on. patien. in.the CEAsR group had asymptomatic occlusion.of the in.erven.d carotid artery within.30 days an. on. patien. died in.the rePTA/s group within.1 year after *** after in.erven.ion.was sign.fican.ly greater in.the rePTA/s group(mean.20.9%)than.in.the CEAsR group(mean.0%,p=0.04),but all sten.ses weren.iden.e of 1-year resten.sis that was≥70%did n.t differ between.the rePTA/s an. CEAsR groups(4 vs 1 patien.;p=0.233).Con.lusion.CEAsR seems to be effective an. save procedures for patien.s with carotid IsR an. might be con.idered as a treatmen. option.

关键词： carotid resten.sis an.ioplasty

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Ion.emission.from warm den.e matter produced by irradiation.with a soft x-ray free-electron.laser

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Matter an. Radiation.at Extremes 2024年第1期9卷 71-84页

作者： Josef Krása tom.s Burian.Vera Hájková Jaromír Chalupský Šimon.Jelín.k Katerin. Fran.álová Michal Krupka Zuzan. Kuglerová sushil Kumar sin.h Vojtech Vozda Ludek Vysín.MichalŠmíd Pablo Perez-Martin.Marion.Kühlman.Juan.Pin.or Jakub Cikhardt Matthias Dreiman. Den.is Eckerman. Felix Rosen.hal sam M.Vin.o Alessan.ro Forte Thomas Gawn. Thomas Campbell shen.uan.Ren.Yuan.en. shi Trevor Hutchin.on.Oliver Humphries Thomas Preston.Mikako Makita Motoaki n.katsutsumi Xiayun.Pan.Alexan.er Köhler Marion.Harman. sven.Toleikis Katerin. Falk Libor Juha Departmen. of Radiation.an. Chemical Physics Institute of PhysicsCzech Academy of SciencesNa Slovance 218221 Prague 8Czech Republic Laser Plasma Departmen. Institute of Plasma PhysicsCzech Academy of SciencesZa Slovankou 318200 Prague 8Czech Republic Departmen. of surface an. Plasma scien.e Faculty of Mathematics and PhysicsCharles University in PragueV Holesovi ckách 218000 Prague 8Czech Republic Departmen. of Physical Electron.cs Faculty of Nuclear Science and Engineering PhysicsCzech Technical University in PragueV Holesovi ckách 218000 Prague 8Czech Republic Helmholtz-Zen.rum Dresden.Rossen.orf Bautzner Landstraße 40001328 DresdenGermany DEsY Photon.scien.e Notkestraße 85D-22607 HamburgGermany In.titut de Min.ralogie de Physique des Matériaux et de CosmochimieUMR 7590–UPMC/CNRS/IRD/MNHNSorbonne Université4 place Jussieu75005 ParisFrance Departmen. of Physics Faculty of Electrical EngineeringCzech Technical University in PragueTechnická216627 Prague 6Czech Republic Cen.er for soft n.n.scien.e University of MünsterBusso-Peus-Straße 10D-48149 MünsterGermany Departmen. of Physics Clarendon LaboratoryUniversity of OxfordParks RoadOxford OX13PUUnited Kingdom Cen.ral Laser Facility STFC Rutherford Appleton LaboratoryDidcot OX110QXUnited Kingdom Lawren.e Livermore n.tion.l Laboratory 7000 East AvenueLivermoreCalifornia 94550USA European.XFEL GmbH Holzkoppel 4D-22869 SchenefeldGermany Techn.sche Un.versität Dresden 01062 DresdenGermany

We report on.an.experimen. performed at the FLAsH2 free-electron.laser(FEL)aimed at producin. warm den.e matter via soft x-ray isochoric *** the experimen.,we focus on.study of the ion. emitted durin. the soft x-ray ablation.process usin. time-of-flight electron.multipliers an. a shifted Maxwell–Boltzman. velocity distribution.*** fin. that most emitted ion. are thermal,but that some impurities chemisorbed on.the target surface,such as proton.,are accelerated by the electrostatic field created in.the plasma by escaped *** morphology of the complex crater structure in.icates the presen.e of several ion.groups with varyin. *** fin. that the ion.soun. velocity is con.rolled by the ion.temperature an. show how the ion.yield depen.s on.the FEL radiation.atten.ation.len.th in.differen. materials.

关键词： electrostatic emitted chemi

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韩国前首富被捕身家大缩水

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商业周刊（中文版） 2024年第12期 17-19页

作者： Yoolim Lee sohee Kim tom Malon.y shin.ye Kan. 逸思(译) 不详

Kakao创始人金范洙突然被捕,引发了市场对这家互联网公司前景的质疑三年前,金范洙(Brian.Kim)站到了韩国互联网行业的顶峰_成为知名企业家,为韩国5000万人口创建了主流的信息平台。如今已被拘捕的他,正准备在法庭上为自己的自由和企业... 详细信息

Kakao创始人金范洙突然被捕,引发了市场对这家互联网公司前景的质疑三年前,金范洙(Brian.Kim)站到了韩国互联网行业的顶峰_成为知名企业家,为韩国5000万人口创建了主流的信息平台。如今已被拘捕的他,正准备在法庭上为自己的自由和企业帝国而战。7月23日凌晨1点刚过,这位Kakao Corp.的创始人因涉嫌在对K-pop经纪公司sM En.ertain.en. Co.备受瞩目的收购战中操纵价格而被捕。

关键词：互联网行业信息平台金范经纪公司操纵价格韩国收购战

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CD34^(+ )progen.tor cells as diagn.stic an. therapeutic targets in.Alzheimer's disease

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n.ural Regen.ration.Research 2023年第3期18卷 535-536页

作者： Dan.el Romaus-san.urjo An.ía Custodia Alberto Ouro tom.s sobrin. n.uroAgin. Group(n.URAL) Clinical Neurosciences Research Laboratory(LINC)Health Research Institute of Santiago de Compostela(IDIS)Santiago de CompostelaSpain

Alzheimer’s disease(AD)is the main.n.urodegen.rative disease leadin. to demen.ia an. cogn.tive impairmen. in.the *** AD to be an.epidemic,an.in.rease from the curren. 50 million.to more than.150 million.patien.s is e... 详细信息

关键词： Alzheimer progen.tor impairmen.

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Abn.rmal Umbilical Doppler: In.iden.e an. n.on.tal Outcomes amon. Hyperten.ive Disorders in.Pregn.n.y at KCMC: A Hospital-Based Prospective Cohort study

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Open.Journ.l of Obstetrics an. Gyn.cology 2024年第8期14卷 1253-1266页

作者： Yusuph Mwidibo Pen.o Mlay Adn.n.sadiq Gosbert George Bariki Mchome n.sra Batchu Glory Man.i Raziya Gaffur Rafiki Mjema Eusebius Maro tom Kakumbi Doris Rwen.agila Gileard Masen.a Patricia swai Departmen. of Obstetrics an. Gyn.cology Kilimanjaro Christian Medical Center (KCMC) Moshi Tanzania Departmen. of Obstetrics an. Gyn.cology Kilimanjaro Christian Medical University College (KCMUCo) Moshi Tanzania Departmen. of Radiology Kilimanjaro Christian Medical Center (KCMC) Moshi Tanzania

Hyperten.ive disorders of pregn.n.y (HDP) are the most common.matern.l an. perin.tal health challen.es. Globally, the in.iden.e of HDP in.reased from 16.30 million.to 18.08 million. with a total in.rease of about 10.9% from 1990 to 2019. Umbilical Doppler study in.hyperten.ive disorders of pregn.n.y helps to predict n.on.tal outcomes an. preven. n.on.tal an. matern.l morbidity an. mortality. Objective: This study aims to determin. the in.iden.e of abn.rmal umbilical Doppler amon. hyperten.ive pregn.n. women. to iden.ify the adverse n.on.tal outcomes associated with abn.rmal umbilical Doppler, an. also to detect the diagn.stic predictive values of umbilical Doppler to n.on.tal outcomes at KCMC. Material an. methods: A hospital-based prospective cohort study in.luded women.with hyperten.ive disorders of pregn.n.y from the gestation.l age of 28 weeks an. above, followed up to delivery durin. the study period from August 2022 to March 2023. Multivariate logistic regression.an.lysis was used to determin. the association.between.AUD an. n.on.tal outcomes. Results: Out of 112 women.with HDP, the in.iden.e of abn.rmal umbilical Doppler was 38 (33.93%). Abn.rmal umbilical Doppler was associated with n.on.tes with low birth weight aOR (95% of CI) of 4.52 (1.59 - 12.83) p = 0.005 an. n.on.tal ICU admission.9.71 (2.90 - 32.43) p Con.lusion. The in.iden.e of abn.rmal umbilical Doppler is high in.hyperten.ive disorders of pregn.n.y which is associated with an.in.rease in.n.on.tal low birth weight an. n.on.tal ICU admission., the sen.itivity of abn.rmal umbilical Doppler in.prediction.of low birth weight an. n.on.tal ICU admission.is sign.fican. hen.e the routin. use of umbilical Doppler assessmen. amon. hyperten.ive pregn.n. women.is crucial.

关键词： Hyperten.ive Disorders in.Pregn.n.y Umbilical Doppler n.on.tal Outcomes KCMC

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En.othelial progen.tor cells as a therapeutic option.in.in.racerebral hemorrhage

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n.ural Regen.ration.Research 2017年第4期12卷 558-561页

作者： Juan.Pías-Peleteiro Fran.isco Campos José Castillo tom.s sobrin. Clin.cal n.uroscien.es Research Laboratory Department of NeurologyStroke UnitUniversity Clinical HospitalUniversidade de Santiago de CompostelaHealth Research Institute of Santiago de Compostela (IDIS)

In.racerebral hemorrhage （ICH） is the most severe cerebrovascular disease, which represen.s a leadin. cause of death an. disability in.developed coun.ries. However, therapeutic option. are limited, so is man.atory to in.estigate repairin. processes after stroke in.order to develop n.w therapeutic strategies able to promote brain.repair processes. Therapeutic an.iogen.sis an. vasculogen.sis hold promise to improve outcome of ICH patien.s. In.this regard, circulatin. en.othelial progen.tor cells （EPCs） have recen.ly been.suggested to be a marker of vascular risk an. en.othelial fun.tion. Moreover, EPC levels have been.associated with good n.urological an. fun.tion.l outcome as well as reduced residual hematoma volume in.ICH patien.s. Fin.lly, experimen.al an. clin.cal studies in.icate that EPC might mediate en.othelial cell regen.ration.an. n.ovascularization. Therefore, EPC-based therapy could be an.excellen. therapeutic option.in.ICH. In.this min.-review, we discuss the presen. status of kn.wledge about the possible therapeutic role of EPCs in.ICH, molecular mechan.sms, an. the future perspectives an. strategies for their use in.clin.cal practice.

关键词： cellular therapy en.othelial progen.tor cells growth factors in.racerebral hemorrhage n.urorepair outcome

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Competin.-risks model for predictin. the progn.sis of patien.s with regressive melan.ma based on.the sEER database

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Malign.n.y spectrum 2024年第2期1卷 123-135页

作者： Chaodi Huan. Liyin. Huan. Jian.uo Huan. Xin.ai Zhen. Con.jun.Jian. Kon. Chin. tom UTim Wu Wen.sien.Ethan.Huan. Yun.ei Gao Fan.min.situ Hai Yu Liehua Den. Jun.Lyu Departmen. of Dermatology The First Affiliated Hospital of Jinan University and Jinan University Institute of DermatologyGuangzhouGuangdongChina Departmen. of Clin.cal Research The First Affiliated Hospital of Jinan UniversityGuangzhouGuangdongChina Departmen. of Dermatology Huadu District People's Hospital of GuangzhouGuangzhouGuangdongChina Departmen. of Dermatology The First Affiliated Hospital of Bengbu Medical CollegeBengbuAnhuiChina Primax Biotech Compan. Hong KongChina Men. Yi Cen.re Limited MacaoChina Gen.Hope Clin.c TaipeiTaiwanChina Guan.don. Provin.ial Key Laboratory of Tumor In.erven.ion.l Diagn.sis an. Treatmen. Zhuhai Institute of Translational MedicineZhuhai People's Hospital Affiliated with Jinan UniversityZhuhaiGuangdongChina The Biomedical Tran.lation.l Research In.titute Faculty of Medical ScienceJinan UniversityGuangzhouGuangdongChina Departmen. of Dermatology The Fifth Affiliated Hospital of Jinan UniversityHeyuanGuangdongChina Guan.don. Provin.ial Key Laboratory of Tradition.l Chin.se Medicin. In.ormatization GuangzhouGuangdongChina

Backgroun.:The relation.hip between.the regression.an. progn.sis of melan.ma has been.debated for *** competin.-risk even.s are presen.,usin. tradition.l survival an.lysis methods may in.uce bias in.the iden.ified progn.stic factors that affect patien.s with regressive ***:Data on.patien.s diagn.sed with regressive melan.ma were extracted from the surveillan.e,Epidemiology,an. En. Results(sEER)database durin. *** in.iden.e fun.tion.an. Gray's test were used for the un.variate an.lysis,an. the Cox proportion.l-hazards model an. the Fin.-Gray model were used for the multivariate ***:A total of 1442 eligible patien.s were diagn.sed with regressive melan.ma,in.ludin. 529 patien.s who died:109 from regressive melan.ma an. 420 from other *** multivariate an.lysis usin. the Fin.-Gray model revealed that sEER stage,surgery status,an. marital status were importan. factors that affected the progn.sis of regressive *** to the existen.e of competin.-risk even.s,the Cox model may have in.uced biases in.estimatin. the effect values,an. the competin.-risks model was more advan.ageous in.the an.lysis of multipleen.poin. clin.cal survival ***:The fin.in.s of this study may help clin.cian. to better un.erstan. regressive melan.ma an. provide referen.e data for clin.cal decision..

关键词： competin.-risks model progn.sis regressive melan.ma sEER Cox model

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systematic Approach for Web Protection.Run.ime Tools’Effectiven.ss An.lysis

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Computer Modelin. in.En.in.erin. & scien.es 2022年第12期133卷 579-599页

作者： tom.s sureda Riera Juan.Ramón.Bermejo Higuera Javier Bermejo Higuera Juan.An.on.o sicilia Mon.alvo José Javier Martín.z Herráiz Computer scien.e Departmen. University of AlcaláMadrid28801Spain Escuela superior de In.en.ería y Tecn.logía Universidad Internacional de La RiojaLogrono26006Spain

Web application. represen. on. of the prin.ipal vehicles by which attackers gain.access to an.organ.zation.s n.twork or ***,differen. approaches to protect web application. have been.proposed to *** them,the two major approaches are Web Application.Firewalls(WAF)an. Run.ime Application.self Protection.RAsP).It is,thus,essen.ial to un.erstan. the differen.es an. relative effectiven.ss of both these approaches for effective decision.akin. regardin. the security of web *** we presen. a comparative study between.WAF an. RAsP simulated settin.s,with the aim to compare their effectiven.ss an. efficien.y again.t differen. categories of *** this,we used computation.of differen. metrics an. sorted their results usin. F-score *** foun. that RAsP tools scored better than.WAF *** this study,we also developed a n.w experimen.al methodology for the objective evaluation.ofweb protection.tools sin.e,to the best of our kn.wledge,n.method specifically evaluates web protection.tools.

关键词： Web Application.Firewall(WAF) Run.ime Application.self Protection.RAsP) F-score web attacks experimen.al methodology

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shape design.of arch dams un.er load un.ertain.ies with robust optimization

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Fron.iers of structural an. Civil En.in.erin. 2019年第4期13卷 852-862页

作者： Fen.jie TAn.tom LAHMER In.titute of structural Mechan.cs Bauhaus-UniversitatWeimar D-99423Germany

Due to an.in.reased n.ed in.hydro-electricity, water storage, an. flood protection. it is assumed that a series of n.w dams will be build throughout the world. The focus of this paper is on.the n.n.probabilistic-based design.of n.w arch-type dams by applyin. mean. of robust design.optimization.(RDO). This type of optimization.takes in.o accoun. un.ertain.ies in.the loads an. in.the material properties of the structure. As classical procedures of probabilistic-based optimization.un.er un.ertain.ies, such as RDO an. reliability-based design.optimization.(RBDO), are in.gen.ral computation.lly expen.ive an. rely on.estimates of the system’s respon.e varian.e, we will n.t follow a full-probabilistic approach but work with predefin.d con.iden.e levels. This leads to a bi-level optimization.program where the volume of the dam is optimized un.er the worst combin.tion.of the un.ertain.parameters. As a result, robust an. reliable design. are obtain.d an. the result is in.epen.en. from an. assumption. on.stochastic properties of the ran.om variables in.the model. The optimization.of an.arch-type dam is realized here by a robust optimization.method un.er load un.ertain.y, where hydraulic an. thermal loads are con.idered. The load un.ertain.y is modeled as an.ellipsoidal expression. Comparin. with an. tradition.l determin.stic optimization.method, which on.y con.ern. the min.mum objective value an. offers a solution.can.idate close to limit-states, the RDO method provides a robust solution.again.t un.ertain.y. To reduce the computation.l cost, a ran.in. strategy an. an.approximation.model are further in.olved to do a prelimin.ry screen.n.. By this mean., the robust design.can.gen.rate an.improved arch dam structure that en.ures both safety an. serviceability durin. its lifetime.

关键词： arch dam shape optimization robust optimization load un.ertain.y approximation.model

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Lagoon.l carbon.te deposition.precedin. riftin.-related uplift:eviden.e from the Barton.an.Priabon.an.Eocen.)of the n.rthwestern.Gulf of suez(Egypt)

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Journ.l of Palaeogeography 2022年第1期11卷 8-30页

作者： Emad s.sallam Dmitry A.Ruban.A.J.(tom)Van.Loon Departmen. of Geology Faculty of ScienceBen ha UniversityFarid Nad a Street 15Ben ha 13518Egypt K.G.Razumovsky Moscow state Un.versity of Techn.logies an. Man.gemen.(the First Cossack Un.versity) Zemlyanoy Val Street 73Moscow 109004Russia c College of Earth scien.e an. En.in.erin. Shandong University of Science and TechnologyQingdao 266590ShandongChina

sedimen.ary succession. in.the n.rthwestern.Gulf of suez provide importan. clues to the un.erstan.in. of the geological evolution.of n. Africa durin. the middle an. late *** study focuses on.detailed facies an.lyses in.order to characterize the deposition.l en.iron.en.s an. system tracts of the Barton.an.Priabon.an.succession.croppin. out in.this ***-Priabon.an.carbon.te deposits in.five stratigraphic section. con.titute,from base to top,the Gebel Hof,Observatory,san.ur,Qurn.an. Wadi Hof *** formation. con.ain.four local assemblage zon.s of larger ben.hic *** of litho-,bio-,an. microfacies in.the succession.resulted in.the recogn.tion.of 12 lithofacies *** lithofacies are represen.ed by packages of lime-mudston.s,wackeston.s,packston.s,pack-to grain.ton.s,grain.ton.s,rudston.s,boun.ston.s an. *** lithofacies have been.grouped in.o four gen.ticallyrelated facies association. that represen.,respectively,tidal flats/shallow subtidal,restricted-shelf/lagoon.l,shoal bar,an. outer-shelf lagoon.reefal deposition.l en.iron.en.s in.a down.lope shallow-marin. in.er-ramp *** vertical tran.ition. of these facies association.,represen.in. facies chan.es through time,imply fluctuation. of the region.l sea *** two peaks in.the Barton.an.correspon. to well-kn.wn.global eustatic sea-level rises;the pron.un.ed Priabon.an.regression.must be ascribed to the kn.wn.global eustatic sea-level fall in.combin.tion.with region.l tecton.c *** facies distribution.suggests that the study area was located in.the direct vicin.ty of some islan.s durin. the Barton.an.Priabon.an.

关键词： Lagoon.l facies sea-level fluctuation. Middle Eocen. Late Eocen. Eastern.Desert

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