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Diurnal variation of precipitable water vapor over Central and South America

Geodesy and Geodynamics 2020年第6期11卷 426-441页

作者： Amalia Meza Luciano Mendoza María Paula Natali clara bianchi Laura Fernández Laboratorio de Meteorología espacial Atmosfera terrestreGeodesiaGeodinamicadiseno de Instrumentaly Astrometría(MAGGIA)Facultad de Ciencias Astronomicasy Geofísicas(FCAG)Universidad Nacional de La Plata(UNLP)Paseo del Bosque s/nB1900FWALa Plata(UNLP)Paseo del Bosque s/nB1900FWALa PlataArgentina Consejo Nacional de Investigacion Científicay Tecnica Godoy Cruz 2290C1425FQBBuenos AiresArgentina

Annual and seasonal diurnal precipitable water vapor(PWV)variations over Central and South America are analyzed for the period *** values were obtained from Global Navigation Satellite Systems(GNSS)observations of sixty-nine GNSS tracking *** by climate categories show that PWV values for temperate,polar and cold dry climate have a positive skewed distribution and for tropical climates(except for monsoon subtype)show a negative skewed *** diurnal PWV and surface temperatures(T)anomaly datasets are analyzed by using principal components analysis(PCA).The first two modes represent more than 90%of the PWV *** first PCA mode of PWV variability shows a maximum amplitude value in the late afternoon few hours later than the respective values for surface temperature(T),therefore the temperature and the surface conditions(to yield evaporation)could be the main agents producing this variability;PWV variability in inland stations are mainly represented by this *** second mode of PWV variability shows a maximum amplitude at midnight,a possible explanation of this behavior is the effect of the sea/valley *** coastal and valley stations are affected by this mode in most ***,the"undefined"stations,surrounded by several water bodies,are mainly affected by the second mode with negative *** the seasonal analysis,both the undefined and valley stations constitute the main cases that show a sea or valley breeze only during some seasons,while the rest of the year they present a behavior according to their temperature and the surface *** a result,the PCA proves to be a useful numerical tool to represent the main sub-daily PWV variabilities.

关键词： Precipitable water vapor(PWV) Global navigation satellite systems(GNSS) Koppen and Geiger climate type classification(K-G) Surface temperature Principal component analysis(PCA)

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尼美舒利及其他非甾体类抗炎药物肝毒性的队列研究

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英国医学杂志中文版 2004年第3期7卷 190-190页

作者： Giuseppe Traversa clara bianchi Roberto Da Cas Iosief Abraha Francesca Menniti-Ippolito Mauro Venegoni 李伟

目的:与其他非甾体类抗炎药物相比较,评价尼美舒利(nimesulide)急性肝毒性的危险性。设计:回顾性队列研究和巢式病例对照研究。地点:意大利翁布里亚地区(Umbria region)。参与者:1997年1月～2001年12月31日间400000例当前、近期或者... 详细信息

目的:与其他非甾体类抗炎药物相比较,评价尼美舒利(nimesulide)急性肝毒性的危险性。设计:回顾性队列研究和巢式病例对照研究。地点:意大利翁布里亚地区(Umbria region)。参与者:1997年1月～2001年12月31日间400000例当前、近期或者过去应用过非甾体类抗炎药物者(近2百万个处方)。

关键词：尼美舒利非甾体类抗炎药药物毒性肝损伤

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Coal petrology analysis and implications in depositional environments from upper Cretaceous to Miocene:a study case in the Eastern Cordillera of Colombia

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International Journal of Coal Science & Technology 2021年第5期8卷 869-896页

作者： clara Guatame Marco Rincon Servicio Geologico Colombiano diagonal 53 n.°34-53BogotaColombia

The Piedemonte Llanero Basin is located on the eastern side of the Eastern Cordillera of the Colombian *** has been the subject of numerous geological studies carried out for the oil sector,*** study presents the coalpetrographical features of 15 coal seams of four geological formations from Late Cretaceous to Middle Miocene(Chipaque formation,Palmichal group,Arcillas del Limbo formation,and San Fernando formation).Analysis of 33 samples indicates enrichment in vitrinite,while liptinite and inertinite concentrations vary according to the stratigraphic *** indicates that the coal range gradually decreases from highly volatile bituminous C(Chipaque formation)to subbituminous C(San Fernando formation).The microlithotypes with the highest concentrations are clarite and *** composition and coal facies indicate changes in the depositional conditions of the *** precursor peat from Late Cretaceous to Late Paleocene accumulated under limnic conditions followed by telmatic in Late Eocene-Early *** coal facies indices show wet conditions in forest swamps with variations in the flooding surface,influxes of brackish water and good tissue *** tectonic conditions along the Piedemonte Llanero basin is evident,from post-rift to foreland basin,evidenced by oxic and anoxic periods reflected in the maceral composition and its *** coal environment corresponds to an estuarine system started in the Chipaque formation evolving to the lacustrine conditions in the San Fernando formation.

关键词： Eastern cordillera basin Northern Andes Coal Organic petrology

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Model Identification and Control of Electromagnetic Actuation in Continuous Casting Process With Improved Quality

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IEEE/CAA Journal of Automatica Sinica 2023年第1期10卷 203-215页

作者： Isabela Birs Cristina Muresan Dana Copot clara Ionescu Research Group of Dynamical Systems and Control Faculty of Engineering and ArchitectureGhent University and with EEDT Decision&ControlFlanders Make ConsortiumTech Lane Science Park 125 and 131B-9052 GhentBelgium.I.Birs the Automation Department Faculty of Automation and Applied InformaticsTechnical University of Cluj-NapocaRomania IEEE

This paper presents an original theoretical framework to model steel material properties in continuous casting line process. Specific properties arising from non-Newtonian dynamics are herein used to indicate the natural convergence of distributed parameter systems to fractional order transfer function models. Data driven identification from a real continuous casting line is used to identify model of the electromagnetic actuator device to control flow velocity of liquid steel. To ensure product specifications, a fractional order control is designed and validated on the system. A projection of the closed loop performance onto the quality assessment at end production line is also given in this paper.

关键词： Electromagnetic actuator fractional order control fractional order system model non-Newtonian material

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A Dynamic Signaling Path to Chromatin-Level Control of Plant Drought Response

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Molecular Plant 2019年第3期12卷 292-294页

作者： clara Bourbousse Fredy Barneche Institutde Biologie de I'Ecole Normale Superieure(IBENS) Ecole Normale SuperieureCNRSINSERMPSL University75005 ParisFrance

As sessile organisms, plants display a high capacity for phenotypic adaptations allowing them to meet the constraints of a changing local environment. This plasticity notably originates from the aptitude of plants to adjust their development and physiology throughout their lifetime to reach an optimal trade-off between growth and fitness. As in all eukaryotes, dynamic control of plant gene expression in different cell types is dependent on multiple regulatory layers that often converge onto chromatin-based mechanisms. Dynamic control of chromatin composition and organization has a strong impact on the cellular transcriptional program, notably contributing to selective modulation of gene expression in a reversible manner. Chromatin state changes generally involve remodeling of nu cleosome positio ning, incorporatio n of nu cleosomal and lin ker histone variants, and DNA and histone modifications recognized by cognate readers. Together, these processes modulate the access and activity of trans-acting factors such as transcription factors and RNA polymerases. Temporary shifts between transcriptionally permissive and repressive chromatin states rely on various mechanisms, among which is the rapid reversion of a “responsive” chromatin status through active erasure of newly established features.

关键词： Dynamic Signaling Path Chromatin-Level Control

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A 15-year-Long catalog of seismicity in the Eastern Tennessee Seismic Zone(ETSZ)using matched filter detection

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Earthquake Research Advances 2023年第1期3卷 92-105页

作者： clara Daniels Zhigang Peng School of Earth and Atmospheric Sciences Georgia Institute of TechnologyAtlanta311 Ferst DrAtlantaGA30318USA Applied Research Associates BurlingtonMAUSA

We present a detailed catalog of 13671 earthquakes in the Eastern Tennessee Seismic Zone(ETSZ)that spans January 1,2005 to July 31,*** apply a matched filter detection technique on over 15 years of continuous data,resulting in arguably the most complete catalog of seismicity in the ETSZ *** magnitudes of newly detected events are determined by computing the amplitude ratio between the detections and templates using a principal component *** also compute the b-value for the new catalog and comparatively relocate a subset of newly detected events using XCORLOC and hypoDD,which shows a more defined structure at *** find the greatest concentration along and to the east of the New York-Alabama Lineament,as defined by the magnetic anomaly,supporting the argument that this feature likely is related to the generation of seismicity in the *** examine seismicity in the vicinity of the Watts Bar Reservoir,which is located about 5 km from the epicenter of the M_(W) 4.4 December 12,2018 Decatur,Tennessee earthquake,and find possible evidence for reservoir modulated seismicity in this *** also examine seismicity in the entire ETSZ to search for a correlation between shallow earthquakes and seasonal hydrologic *** results show limited evidence for hydrologicallydriven shallow seismicity due to seasonal groundwater levels in the ETSZ,which contradicts previous studies hypothesizing that most intraplate earthquakes are associated with the dynamics of hydrologic cycles.

关键词： Eastern Tennessee Seismic Zone Matched filter detection Intraplate earthquakes Reservoir modulated seismicity

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Gastric cancer research in Mexico:A public health priority

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World Journal of Gastroenterology 2014年第16期20卷 4491-4502页

作者： clara Luz Sampieri Mauricio Mora Instituto de Salud Pública Universidad VeracruzanaAv. Luis Castelazo AyalaCol. Industrial ánimas91190 XalapaVeracruzMéxico Facultad de Medicina Universidad Veracruzana.Médicos y OdontólogosCol. Virginia Cordero91120 XalapaVeracruzMéxico

This study aimed review studies conducted on Mexican patients diagnosed with gastric cancer and/or diseases associated with its development,in which at least one Mexican institute has participated,and to assess their contributions to the primary and secondary prevention of this disease.A search of the Medline database was conducted using the following keywords:gastric/stomach cancer,*** of the Mexican population were selected in which at least one Mexican Institute had participated and where the findings could support public policy proposals directed towards the primary or secondary prevention of gastric *** the148 studies found in the Medline database,100 were discarded and 48 were *** to the analysis presented,these studies were classified as:epidemiology of gastric cancer(5/48);risk factors and protectors relating to gastric cancer(9/48);relationship between Helicobacter pylori and pathologies associated with gastric cancer and the development of the disease(16/48);relationship between the Epstein-Barr virus and pathologies associated with gastric cancer and the development of the disease(3/48);molecular markers for the development of diseases associated with gastric cancer and gastric cancer(15/48).Mexico requires a program for the prevention and control of gastric cancer based on national health *** should be produced by a multidisciplinary committee of experts who can propose actions that are relevant in the current national *** few studies of gastric cancer conducted on the Mexican population in national institutes highlight the poor connection that currently exists between the scientific community and the health sector in terms of resolving this health *** policies for health research should support projects with findings that can be translated into benefits for the *** review serves to identify national research groups studying gastric cancer in the Mexican population.

关键词： Gastric cancer Mexico Research Prevention Public health

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Invasive strategy in elderly patients with acute coronary syndrome in 2018: close to the truth?

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Journal of Geriatric Cardiology 2019年第2期16卷 114-120页

作者： Sergio García-Blas clara Bonanad Juan Sanchis Servei de Cardiologia Hospital Clínic Universitari de València INCLIVA Universitat de ValènciaCIBERCV

Elderly population constitutes an increasingly larger proportion of patients admitted for acute coronary syndromes(ACS).The optimal management of ACS in these patients is still a challenge due to their clinical peculiarities and the paucity of specific data,and they have been traditionally managed more conservatively mainly based on subjective *** ST^segment elevation acute myocardial infarction urgent reperfusion is the standard of care and there is no upper age *** non-ST segment elevation acute myocardial infarction evidence is controversial,incomplete and mainly focused on chronological *** a strict conservative strategy should be avoided,routine invasive strategy may reduce the occurrence of myocardial infarction and need for revascularization at follow-up with no established benefit in terms of *** characteristics associated with aging,such as comorbidities and frailty,further discriminate patient's risk beyond *** is scarce,but it suggests that these features may modulate the benefit of invasive strategy in this *** trials should clarify the optimal management of ACS based on these parameters.

关键词： Acute coronary syndromes Comorbidity Frailty Percutaneous coronary intervention The elderly

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Synaptic alterations as a common phase in neurological and neurodevelopmental diseases: JNK is a key mediator in synaptic changes

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Neural Regeneration Research 2023年第3期18卷 531-532页

作者： clara Alice Musi Carlo Bonadonna Tiziana Borsello Department of Pharmacological and Biomolecular Sciences Universitàdegli Studi di MilanoMilanoItaly Mario Negri Insitute for Pharmacolgical Research-IRCCS MilanoItaly

Brain synapses play a key role in neuronal communication:this“conversation”is at the basis of all brain activities and synaptic dysfunction leads to brain *** study the modulators of this crucial synaptic function and we here present the evidence supporting the c-Jun N-terminal kinase(JNK)pathway as a pivotal actor in this scenario.

关键词： alterations diseases neurological

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Clinical implications of endogenous testosterone density on prostate cancer progression in patients with very favorable low and intermediate risk treated with radical prostatectomy

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Asian Journal of Andrology 2023年第5期25卷 556-563页

作者： Antonio Benito Porcaro Alessandro Tafuri Andrea Panunzio clara Cerrato Alberto bianchi Sebastian Gallina Stefano Vidiri Damiano D'Aietti Emanuele Serafin Giovanni Mazzucato Alessandro Princiotta Davide Brusa Matteo Brunelli Vincenzo Pagliarulo Maria Angela Cerruto AlessandroAntonelli Department of Urology University of VeronaIntegrated University Hospital of VeronaVerona 37126Italy Department of Urology Vito Fazzi HospitalLecce 73100Italy Department of Pathology University of VeronaIntegrated University Hospital of VeronaVerona 37126Italy

We tested the association between endogenous testosterone density(ETD;the ratio between endogenous testosterone[ET]and prostate volume)and prostate cancer(PCa)aggressiveness in very favorable low-and intermediate-risk PCa patients who underwent radical prostatectomy(RP).Only patients with prostate-specific antigen(PSA)within 10 ng ml^(-1),clinical stage T1c,and International Society of Urological Pathology(IsUP)grade group 1 or 2 were *** ET levels up to 350 ng dl^(-1)were classified as *** quantitation density factors were evaluated as the ratio between percentage of biopsy-positive cores and prostate volume(biopsy-positive cores density,BPCD)and the ratio between percentage of cancer invasion at final pathology and prostate weight(tumor load density,TLD).Disease upgrading was coded as ISUP grade group>2,and progression as recurrence(biochemical and/or local and/or distant).Risk associations were evaluated by multivariable Cox and logistic regression *** 320 patients,151(47.2%)had intermediate-risk ***(median:402.3 ng dl^(-1))resulted abnormal in 111(34.7%)cases(median ETD:9.8 ng dl^(-1)ml^(-1)).Upgrading and progression occurred in 109(34.1%)and 32(10.6%)cases,*** was predicted by ISUP grade group 2(hazard ratio[HR]:2.290;P=0.029)and upgrading(HR:3.098;P=0.003),which was associated with ISUP grade group 2(odds ratio[OR]:1.785;P=0.017)and TLD above the median(OR:2.261;P=0.001).After adjustment for PSAdensity and bodymass index(BMI),ETDabovethemedianwas positivelyassociatedwithBPCD(OR:3.404;P<0.001)and TLD(OR:5.238;P<0.001).Notably,subjects with abnormal ET were more likely to have higher BPCD(OR:5.566;P=0.002),as well as TLD(OR:14.998;P=0.016).Independently by routinely evaluated factors,as ETD increased,BPCD and TLD increased,but increments were higher for abnormal ET *** very favorable cohorts,ETD may further stratify the risk of aggressive PCa.

关键词： endogenous testosterone density prostate cancer radical prostatectomy tumor progression

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