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Do aphids actively search for ant partners？

Insect Science 2015年第2期22卷 283-288页

作者： Christophe Y. Fischer Maryse Vanderplanck Georges C. Lognay claire Detrain Francois J. Verheggen Laboratory of Analytical Chemistry University of Liege Gembloux Agro-Bio Tech Gembloux Research Institute of Biosciences Laboratory of Zoology University of Mons Mons Unit of Social Ecology Universit6 Libre de Bruxelles Brussels Department of Functional and Evolutionary Entomology University of Liege Gembloux Agro-Bio Tech Gembloux Belgium

The aphid-ant mutnalistic relationships are not necessarily obligate for neither partners but evidence is that such interactions provide them strong advantages in terms of global fitness. While it is largely assumed that ants actively search for their mutualistic partners namely using volatile cues; whether winged aphids （i.e., aphids＇ most mobile form） are able to select ant-frequented areas had not been investigated so far. Ant-frequented sites would indeed offer several advantages for these aphids including a lower predation pressure through ant presence and enhanced chances of establishing mutuaslistic interactions with neighbor ant colonies. In the field, aphid colonies are often observed in higher densities around ant nests, which is probably linked to a better survival ensured by ants＇ services. Nevertheless, this could also result from a preferential establishment of winged aphids in ant-frequented areas. We tested this last hypothesis through different ethological assays and show that the facultative myrmecophilous black bean aphid, Aphisfabae L., does not orientate its search for a host plant preferentially toward ant-frequented plants. However, our results suggest that ants reduce the number of winged aphids leaving the newly colonized plant. Thus, ants involved in facultative myrmecophilous interactions with aphids appear to contribute to structure aphid populations in the field by ensuring a better establishment and survival of newly established colonies rather than by inducing a deliberate plant selection by aphid partners based on the proximity of ant colonies.

关键词： ant aphid Aphisfabae Lasius niger mutualism partner research

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Alpha-7 nicotinic acetylcholine receptor agonist treatment in a rat model of Huntington's disease and involvement of heme oxygenase-1

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Neural Regeneration Research 2018年第4期13卷 737-741页

作者： Laura Foucault-Fruchard claire Tronel Sylvie Bodard Zuhal Gulhan Julie Busson Sylvie Chalon Daniel Antier UMR 1253 iBrainUniversité de Tours CHRU de Tours H?pital Bretonneau

Neuroinflammation is a common element involved in the pathophysiology of neurodegenerative *** recently reported that repeated alpha-7 nicotinic acetylcholine receptor（α7 n ACh R） activations by a potent agonist such as PHA 543613 in quinolinic acid-injured rats exhibited protective effects on *** further investigate the underlying mechanism,we established rat models of early-stage Huntington＇s disease by injection of quinolinic acid into the right striatum and then intraperitoneally injected 12 mg/kg PHA 543613 or sterile water,twice a day during 4 *** blot assay results showed that the expression of heme oxygenase-1（HO-1）,the key component of the cholinergic anti-inflammatory pathway,in the right striatum of rat models of Huntington＇s disease subjected to intraperitoneal injection of PHA 543613 for 4 days was significantly increased compared to the control rats receiving intraperitoneal injection of sterile water,and that the increase in HO-1 expression was independent of change in α7 n ACh R *** findings suggest that HO-1 expression is unrelated to α7 n ACh R density and the increase in HO-1 expression likely contributes to α7 n ACh R activation-related neuroprotective effect in early-stage Huntington＇s disease.

关键词： alpha 7 nicotinic receptor PHA 543613 quinolinic acid cholinergic anti-inflammatory pathway neuroinflammation neurodegenerative disease

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Time-series prediction of shellfish farm closure: A comparison of alternatives

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Information Processing in Agriculture 2014年第1期1卷 42-50页

作者： Ashfaqur Rahman Md Sumon Shahriar claire D’Este Greg Smith John McCulloch Greg Timms Autonomous Systems Program CSIRO Computational InformaticsHobartTAS 7000Australia

Shellfish farms are closed for harvest when microbial pollutants are *** pollutants are typically present in rainfall runoff from various land uses in *** currently use a number of observable parameters(river flow,rainfall,salinity)as proxies to determine when to close *** have proposed using the short term historical rainfall data as a time-series prediction problem where we aim to predict the closure of shellfish farms based only on ***-series event prediction consists of two steps:(i)feature extraction,and(ii)prediction.A number of data mining challenges exist for these scenarios:(i)which feature extraction method best captures the rainfall pattern over successive days that leads to opening or closure of the farms?,(ii)The farm closure events occur infrequently and this leads to a class imbalance problem;the question is what is the best way to deal with this problem?In this paper we have analysed and compared different combinations of balancing methods(under-sampling and over-sampling),feature extraction methods(cluster profile,curve fitting,Fourier Transform,Piecewise Aggregate Approximation,and Wavelet Transform)and learning algorithms(neural network,support vector machine,k-nearest neighbour,decision tree,and Bayesian Network)to predict closure events accurately considering the above data mining *** have identified the best combination of techniques to accurately predict shellfish farm closure from rainfall,given the above data mining challenges.

关键词： Aquaculture Shellfish farm closure Data mining Time series data

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品牌总裁爱发帖李维斯陷入文化冲突

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商业周刊（中文版） 2022年第11期 62-69页

作者： claire SUDDATH JANELLE JONES(摄影) 不详

2020年3月,新冠疫情初起,詹妮弗·赛伊(JenniferSey)发现自己跟丈夫和四个孩子被困在了家里,只能在由餐桌改成的临时办公室工作。她不知道这场疫情会如何发展,也不知道它何时能结束。于是她开始在社交媒体上发帖子,而且一发不可收拾。... 详细信息

2020年3月,新冠疫情初起,詹妮弗·赛伊(JenniferSey)发现自己跟丈夫和四个孩子被困在了家里,只能在由餐桌改成的临时办公室工作。她不知道这场疫情会如何发展,也不知道它何时能结束。于是她开始在社交媒体上发帖子,而且一发不可收拾。当时她住在旧金山,那是美国最早一批颁布居家令的城市之一。

关键词：文化冲突社交媒体李维斯赛伊旧金山

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You＇re Kidding

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小学生时代（大嘴英语） 2009年第9期 10-11页

作者： claire

你也许会问：kid不是“小孩”的意思吗？没错，不过在这里kid是动词，意思是“哄骗，嘲弄”。

关键词：小学英语阅读教学阅读材料

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Holographic Grating Formation in Cationic Photopolymers with Dark Reaction

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Chinese Physics Letters 2006年第11期23卷 2960-2963页

作者：尉昊赟曹良才 GU claire 许振丰赫明钊何庆声何树荣金国藩 State Key Laboratory of Precision Measurement Technology and Instruments Tsinghua University Beijing 100084 Department of Electrical Engineering University of California Santa Cruz CA 95064 USA

We propose a new formula to describe the dynamics of holographic grating formation under low intensity pulse exposures in cationic photopolymers, in which the dark reaction contributes dominantly to the grating strength. The formula is based on the living polymerization mechanism and the diffusion-free approximation. The analytical solution indicates that the grating formation time depends on the termination rate constant, while the final grating strength depends linearly on the total exposure energy. These theoretical predictions are verified experimentally using the Aprilis HMC-400μm photopolymer. The results can provide guidelines for the control and optimization of the holographic recording conditions in practical applications.

关键词： DATA-STORAGE MODEL

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The Issue of Precision Agriculture in International Trade： An Analysis in Terms of Subsidies

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Journal of Agricultural Science and Technology(A) 2012年第1期2卷 120-130页

作者： claire Baldin University of Nice Sophia-Antipolis UMR 6227 CNRS-GREDEG Nice 06000 France

At the present time, world agriculture is influenced by a set of new technologies grouped under the generic name of precision agriculture (PA). Based on a study of the cotton sector, this article examines the effects of adopting PA with regard to international trade. We examine whether PA can contribute to the further destabilization of the terms of trade between countries in Central and West Africa (CWA) and Northern countries. We show that PA can be used by Northern countries at the expense of CWA, since it is used to implement strategic commercial policies based on subsidies. These policies are made more credible by the fact that international authorities cannot easily condemn them.

关键词：国际贸易农业补贴世界农业通用名称精准农业 PA 基础北方

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Effect of phosphodiesterase inhibitors in the bladder

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Asian Journal of Urology 2015年第1期2卷 33-37页

作者： Bilal Chughtai Aizaz Ali claire Dunphy Steven A.Kaplan Weill Cornell Medical College New York CityNYUSA

Many aging men will experience lower urinary tract symptoms(LUTS).Phosphodiesterase type 5(PDE5)inhibitors have shown promise in treating LUTS in these ***5 inhibitors mediate their effects through several pathways including cAMP,NO/cGMP,Kchannel modulated pathways,and the L-cysteine/H2S ***5 inhibitors exert their effect in muscle cells,nerve fibers,and interstitial cells(ICs).The use of PDE5 inhibitors led to improvement in *** included urodynamic ***5 inhibitors may play a significant role in LUTS due to their effect on the bladder rather than the prostate.

关键词： Lower urinary tract symptoms(LUTS) Overactive bladder syndrome(OAB) Phosphodiesterase type 5 inhibitors NO/cGMP cAMP

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Impact of radiotherapy on the immune landscape in oesophageal adenocarcinoma

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World Journal of Gastroenterology 2022年第21期28卷 2302-2319页

作者： Noel E Donlon Maria Davern Fiona O'Connell Andrew Sheppard Aisling Heeran Anshul Bhardwaj Christine Butler Ravi Narayanasamy claire Donohoe James J Phelan Niamh Lynam-Lennon Margaret R Dunne Stephen Maher Jacintha O'Sullivan John V Reynolds Joanne Lysaght Department of Surgery Trinity Translational Medicine InstituteSt James HospitalDublin D08Ireland

BACKGROUND In the contemporary era of cancer immunotherapy,an abundance of clinical and translational studies have reported radiotherapy(RT)and immunotherapies as a viable option for immunomodulation of many cancer subtypes,with many related clinical trials *** locally advanced disease,chemotherapy or chemoradiotherapy followed by surgical excision of the tumour remain the principal treatment strategy in oesophageal adenocarcinoma(OAC),however,the use of the host immune system to improve anti-tumour immunity is rapidly garnering increased support in the curative *** To immunophenotype OAC patients’immune checkpoint(IC)expression with and without radiation and evaluate the effects of checkpoint blockade on cell *** In the contemporary era of cancer immunotherapy,an abundance of studies have demonstrated that combination RT and IC inhibitors(ICIs)are effective in the immunomodulation of many cancer subtypes,with many related clinical trials *** surgical excision and elimination of tumour cells by chemotherapy or chemoradiotherapy remains the gold standard approach in OAC,the propagation of anti-tumour immune responses is rapidly garnering increased support in the curative *** aim of this body of work was to immunophenotype OAC patients’IC expression with and without radiation and to establish the impact of checkpoint blockade on cell *** study was a hybrid combination of in vitro and ex vivo *** of serum immune proteins was performed by enzyme-linked immunosorbent *** cytometry staining was performed to evaluate IC expression for in vitro OAC cell lines and ex vivo OAC *** viability in the presence of radiation with and without IC blockade was assessed by a cell counting kit-8 *** We identified that conventional dosing and hypofractionated approaches resulted in increased IC expression(PD-1,PD-L1,TIM3,TIGIT)in vitro and ex vivo in *** were two distinct subco

关键词： Oesophageal Cancer Radiotherapy Immunotherapy Immunology Surgery Oncology

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Pancreatic cancer: A review of clinical diagnosis, epidemiology, treatment and outcomes

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World Journal of Gastroenterology 2018年第43期24卷 4846-4861页

作者： Andrew McGuigan Paul Kelly Richard C Turkington claire Jones Helen G Coleman R Stephen McCain Centre for Cancer Research and Cell Biology Queen’s University Belfast Department of Pathology Royal Victoria HospitalBelfast Department of Hepatobiliary Surgery Mater Hospital Centre for Public Health Queen’s University Belfast

This review aims to outline the most up-to-date knowledge of pancreatic adenocarcinoma risk, diagnostics, treatment and outcomes, while identifying gaps that aim to stimulate further research in this understudied malignancy. Pancreatic adenocarcinoma is a lethal condition with a rising incidence, predicted to become the second leading cause of cancer death in some regions. It often presents at an advanced stage, which contributes to poor five-year survival rates of 2%-9%, ranking firmly last amongst all cancer sites in terms of prognostic outcomes for patients. Better understanding of the risk factors and symptoms associated with this disease is essential to inform both health professionals and the general population of potential preventive and/or early detection measures. The identification of high-risk patients who could benefit from screening to detect pre-malignant conditions such as pancreatic intraepithelial neoplasia, intraductal papillary mucinous neoplasms and mucinous cystic neoplasms is urgently required, however an acceptable screening test has yet to be identified. The management of pancreatic adenocarcinoma is evolving, with the introduction of new surgical techniques and medical therapies such as laparoscopic techniques and neo-adjuvant chemoradiotherapy, however this has only led to modest improvements in outcomes. The identification of novel biomarkers is desirable to move towards a precision medicine era, where pancreatic cancer therapy can be tailored to the individual patient, while unnecessary treatments that have negative consequences on quality of life could be prevented for others. Research efforts must also focus on the development of new agents and delivery systems. Overall, considerable progress is required to reduce the burden associated with pancreatic cancer. Recent, renewed efforts to fund large consortia and research into pancreatic adenocarcinoma are welcomed, but further streams will be necessary to facilitate the momentum needed to

关键词：癌症治疗胰腺传染病学诊断评论临床风险因素腺癌

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