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International Journal of Ophthalmology(English edition) 2019年第3期12卷 363-368页

作者： Ya-Ru Dong claire E Gustafson Jun Wang Ji-Zhe Cui Takeshi Yoshitomi Department of Ophthalmology the Second Hospital of Jilin University Department of Ophthalmology Akita University School of Medicine Division of Immunology and Rheumatology Department of Medicine Stanford University

AIM: To investigate the alterations in both structure and contractile responsiveness of ocular ciliary artery(OCA) in spontaneously hypertensive rat(SHR).METHODS: In this experiment, 20-week-old male SHR and Wistar Kyoto rat(WKY) were studied. The heart rate(HR), the blood pressure(BP; the systolic BP and the diastolic BP) of rats with an electronic sphygmomanometer were measured. Vascular morphometry and isometric tension measurement were used to investigate the alterations in structure and contractility of ***: A general narrowing of OCAs was observed in SHR compared to the control WYK. In SHR, the media of OCAs were thicker, the luminal diameters were smaller, and the media-to-lumen ratios were higher when compared with WKY(P0.05). Indomethacin(10 μmol/L) decreased the contractions induced by norepinephrine in OCAs from WKY(P0.05).CONCLUSION: Our results demonstrate that the structure and function of OCAs are altered in hypertension. OCAs from SHR are remodeled with decreased lumen diameter and increased media-to-lumen ratio. Moreover, the contractile responsiveness of OCAs from SHR is diminished due to the disruption of vasoconstrictive effect of prostaglandins.

关键词： remodeled structure contractile responsiveness ocular ciliary artery hypertension spontaneously hypertensive rat

Global social archaeologies

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Global social archaeologies

Real-time in situ magnetic measurement of the intracellular biodegradation of iron oxide nanoparticles in a stem cell-spheroid tissue model

作者： Koji Mizoguchi and claire Smith.

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Nano Research 2020年第2期13卷 467-476页

作者： Aurore Van de Walle Alexandre Fromain Anouchka Plan Sangnier Alberto Curcio Luc Lenglet Laurence Motte Yoann Lalatonne claire Wilhelm Laboratoire Matière et Systèmes Complexes MSCUMR 7057CNRS&University of Paris75205Paris Cedex 13France Inserm U1148Laboratory for Vascular Translational ScienceSorbonne Paris NordSorbonne Paris CitéF-93017 BobignyFranc Normafin Sàrl 8 rue Mathilde Girault92300 Levallois-PerretFrance Services de Biochimie et Médecine Nucléaire Hópital Avicenne Assistance Publique-Hôpitaux de ParisF-93009 BobignyFrance

The use of magnetic nanoparticles in nanomedicine keeps expanding and,for most applications,the nanoparticles are internalized in cells then left within,bringing the need for accurate,fast,and easy to handle methodologies to assess their behavior in the cellular ***,a benchtop-size magnetic sensor is introduced to provide real-time precise measurement of nanoparticle magnetism within living *** values obtained with the sensor,of cells loaded with different doses of magnetic nanoparticles,are first compared to conventional vibrating sample magnetometry(VSM),and a strong correlation remarkably validates the use of the magnetic sensor as magnetometer to determine the nanoparticle cellular *** sensor is then used to monitor the progressive intracellular degradation of the nanoparticles,over ***,this real-time in situ measure is performed on a stem cell-spheroid tissue model and can run continuously on a same spheroid,with cells kept alive ***,such continuous magnetic measurement of cell magnetism at the tissue scale does not impact either tissue formation,vibility,or stem cell function,including differentiation and extracellular matrix production.

关键词： magnetic nanoparticles magnetometry real-time in operando measures biodegradation stem cells

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谁在购买“天价”植物

品质 2022年第11期 47-48页

作者： claire Snow(图) 不详

笔者近日复盘自己的年度消费,发现在绿植上花费的费用远远超出了原本的预期。最初买些植物只是为了给家里增添些绿意,却未曾想,这样的消费竟然也会上瘾。而笔者的好友,更是夸张,因为所居住的社区旁边就有一个规模不小的花市,好友几乎每... 详细信息

笔者近日复盘自己的年度消费,发现在绿植上花费的费用远远超出了原本的预期。最初买些植物只是为了给家里增添些绿意,却未曾想,这样的消费竟然也会上瘾。而笔者的好友,更是夸张,因为所居住的社区旁边就有一个规模不小的花市,好友几乎每周都会购人新的植物,并精心拍摄照片,在社交媒体分享。“就控制不住啊,总觉得家里还少这么一盆”,好友总是如此解释自己的购买行为。

关键词：社交媒体购买行为消费植物

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强生消费品业务将自立门户

品质 2022年第11期 90-91页

作者： claire 知行(图) 不详

1、9月28日,强生公司表示,将把专注于消费者健康产品的公司命名为Kenvue,处方药和医疗设备业务将保留强生公司的名称。早在2021年11月,强生就宣布将消费者健康业务剥离并独立上市,如今,这一这备受业界关注的重组计划终于有所进展。2、Ke... 详细信息

1、9月28日,强生公司表示,将把专注于消费者健康产品的公司命名为Kenvue,处方药和医疗设备业务将保留强生公司的名称。早在2021年11月,强生就宣布将消费者健康业务剥离并独立上市,如今,这一这备受业界关注的重组计划终于有所进展。2、Kenvue的品牌名称来自于两个概念。“Ken”取自苏格兰语,意为知识;“Vue”意为视觉。Kenvue这一名称意为通过丰富的知识对人类需求进行深入洞察。

关键词：强生公司品牌名称消费者健康医疗设备消费品处方药人类需求自立门户

Current Practice and Protocols: Endoscopic Laser Therapy for Twin-Twin Transfusion Syndrome

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Maternal-Fetal Medicine 2020年第1期2卷 34-47页

作者： Viral M.Pandya Julien Stirnemann claire Colmant Yves Ville Department of Obstetrics Fetal Medicine and SurgeryHôpital Necker Enfants MaladesAP-HPUniversitéde ParisParis 75015France

The pathophysiology of twin-to-twin transfusion syndrome(TTTS)is complex,and its understanding has evolved along with the evolution and revolution of fetal diagnostic and therapeutic *** the last few decades,several therapeutic interventions have been researched for improving the outcomes in *** present a summary of the current protocols for surveillance,diagnosis,and staging of TTTS in monochorionic *** also describe in detail the technique for treatment of TTTS by endoscopic laser photocoagulation.

关键词： Fetofetal transfusion Fetoscopy Laser photocoagulation Monochorionic twin Twin to twin transfusion syndrome

Contemporary review of the 532 nm laser for treatment of benign prostatic hyperplasia

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Asian Journal of Urology 2015年第2期2卷 102-106页

作者： Bilal Chughtai Leanna Laor claire Dunphy Alexis Te Department of Urology Weill Cornell Medical CollegeNew York Presbyterian HospitalNew YorkNYUSA

Benign prostatic hyperplasia(BPH)is a condition that occurs increasingly with *** established gold standard treatment for BPH has been the electrocautery-based transurethral resection of the prostate(TURP).TURP,however,is associated with several complications and side ***,there is an increasing interest in a number of emerging minimally invasive therapies as alterative treatment *** therapy using the Greenlight laser is a promising alternative to the traditional *** absorption by hemoglobin allows rapid,hemostatic vaporization of prostate *** advantages include avoidance or minimization of complications such as intraoperative fluid absorption,and bleeding,retrograde ejaculation,impotence,and incontinence,as well as its use in treating high volume *** review the use of the Greenlight laser in the treatment of BPH,when comparing complications and advantages in relation to TURP.

关键词： Benign prostatic hyperplasia Laser prostatectomy 532 nm prostatectomy

A Novel Multi-Channel Dispersion Slope Compensator Using Sampled FBG

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光学学报 2003年第S1期23卷 -页

作者： J. J. Pan claire Gu Albert Li Lightwaves 2020 Inc. 1323 Great Mall Drive Milpitas CA 95035 USADepartment of Electrical Engineering University of California at Santa Cruz Santa Cruz CA 95064 USALightwaves 2020 Inc. 1323 Great Mall Drive Milpitas CA 95035 USA

A novel dispersion slope compensator is proposed and fabricated using a sampled fiber grating. The dispersion slope of this compensator is demonstrated to match that of Coming LS fiber for a multi-channel 50GHz WDM sy... 详细信息

关键词： A Novel Multi-Channel Dispersion Slope Compensator Using Sampled FBG in for as WDM with GHz

Bubbles and incentives:an experiment on asset markets

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Economic and Political Studies 2021年第1期9卷 68-89页

作者： Stéphane Robin Katerina Stráznická Marie claire Villeval Grenoble INP Institute of Engineering and Management Grenoble Applied Economics Laboratory(GAEL)University of Grenoble AlpesGrenobleFrance French National Centre for Scientific Research(CNRS) ParisFrance National Institute for Agricultural Research(INRA) ParisFrance Clermont Research Management(CleRMA) University of Clermont AuvergneClermont-FerrandFrance University of Lyon LyonFrance Group of Economic Analysis and Theory(GATE) French National Centre for Scientific Research(CNRS)EcullyFrance Institute of Labour Economics(IZA) BonnGermany

We explore the effects of competitive incentives and of their time horizon on the evolution of both asset prices and trading activity in experimental asset *** compare(i)a no-bonus treatment;(ii)a short-term bonus treatment in which bonuses are assigned to the best performers at the end of each trading period;(iii)a long-term bonus treatment in which bonuses are assigned to the best performers at the end of the 15 periods of the *** find that the existence of bonus contracts does not increase the likelihood of bubbles but it affects their severity,depending on the time horizon of *** with longterm bonus contracts experience lower price deviations and a lower turnover of assets than markets with either no bonuses or long-term bonus ***-term bonus contracts increase price deviations but only when markets include a higher share of male *** the individual level,the introduction of bonus contracts increases the trading activity of males,probably due to their higher competitiveness.

关键词： Asset market bubbles incentives bonuses risk attitudes experiment

Efficient Silencing of Endogenous MicroRNAs Using Artificial MicroRNAs in Arabidopsis thaliana

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Molecular Plant 2011年第1期4卷 157-170页

作者： Andrew L. Eamens claire Agius Nell A. Smith Peter M. Waterhouse Ming-Bo Wang CSIRO Plant Industry GPO Box 1600 Canberra ACT 2601 Australia School of Molecular Bioscience University of Sydney Sydney NSW 2006 Australia

We report here that the expression of endogenous microRNAs （miRNAs） can be efficiently silenced in Arabi- dopsis thaliana （Arabidopsis） using artificial miRNA （amiRNA） technology. We demonstrate that an amiRNA designed to target a mature miRNA directs silencing against all miRNA family members, whereas an amiRNA designed to target the stem-loop region of a miRNA precursor transcript directs silencing against only the individual family member targeted. Furthermore, our results indicate that amiRNAs targeting both the mature miRNA and stem-loop sequence direct RNA silencing through cleavage of the miRNA precursor transcript, which presumably occurs in the nucleus of a plant cell during the initial stages of miRNA biogenesis. This suggests that small RNA （sRNA）-guided RNA cleavage in plants occurs not only in the cytoplasm, but also in the nucleus. Many plant miRNA gene families have been identified via sequencing and bio- informatic analysis, but, to date, only a small tranche of these have been functionally characterized due to a lack of ef- fective forward or reverse genetic tools. Our findings therefore provide a new and powerful reverse-genetic tool for the analysis of miRNA function in plants.

关键词： MicroRNA artificial microRNA RNA silencing.