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多形性胶质母细胞瘤区域性DTI派生的张量指标的诊断作用:p,q,L,cl,Cp,Cs,RA,RD,AD,平均扩散系数和部分各向异性的同时评估

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国际医学放射学杂志 2013年第3期 304-304页

作者： D.Cortez-Conradis R.Favila K.Isaac-olive m.m.rtinez-Lopez C.Rios E.Roldan-Valadez 林江南 Section of Research and Innovation in m.I Magnetic Resonance UnitMedica Sur Clinic & Foundation

目的将较少用于诊断的近12个扩散张量成像(DTI)变量用于对脑肿瘤进行评估。目的是对过去10年报道的张量指标进行综合评估。方法对14例多形性胶质母细胞瘤(GBm.和28例对照组进行回顾性病例对照研究。根据传统颅脑m.序列和DTI的后处理影... 详细信息

目的将较少用于诊断的近12个扩散张量成像(DTI)变量用于对脑肿瘤进行评估。目的是对过去10年报道的张量指标进行综合评估。方法对14例多形性胶质母细胞瘤(GBm.和28例对照组进行回顾性病例对照研究。根据传统颅脑m.序列和DTI的后处理影像计算正常白质(NAWm.,邻近和远处的水肿,环状强化区和囊变区的平均扩散率(m.),部分各向异性(FA),纯各向同性扩散(p),纯各向异性扩散(q),总扩散张量(L),线性张量(cl),平面张量(Cp),球形张量(Cs),相对各向异性(RA),放射状扩散(RD)和轴向扩散系数(AD)。进行ANoVA和AURoC分析。结果所有指标在ANoVA分析中均显示差异具有统计学意义(Pm.作为公认的脑损伤生物标志物,已被其他指标超过。RA结合Cs、cl和CP,可能成为脑肿瘤评估的新指标。DTI张量指标在肿瘤各区域表现出不同的临床适用性。要点①DTI派生的张量指标可定性肿瘤的不同区域。②新的诊断试验功效评估须遵循初级STARD。③多形性胶质母细胞瘤的每个肿瘤区域用不同的张量指标进行检测。④FA和m.并不是肿瘤浸润最好的生物标志物。⑤某些张量指标的诊断作用可被交换应用。

关键词：脑肿瘤扩散张量成像 m.I 敏感度和特异度统计学论题

非增强CT预测阴性结石病人输尿管结石的发生

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国际医学放射学杂志 2012年第6期 604-604页

作者： A.Ciudin m.P.Luque Galvez R.Salvador Izquierdo A.Franco de Castro E.Garcia-Cruz J.Alcover García 赵阳 Urology Departm.nt Hospital Clínic BarcelonaCalle Villarroel 17008036 BarcelonaSpain

目的确定非增强CT(uCT)能否在肾结石形成前发现肾乳头内的钙沉积。方法回顾性分析413例结石病例,确定其中31例有输尿管结石病史且uCT可显示结石,而在结石形成前的uCT检查无阳性发现的病人(结石正在成形组)。设立对照组(31例),由无结石... 详细信息

目的确定非增强CT(uCT)能否在肾结石形成前发现肾乳头内的钙沉积。方法回顾性分析413例结石病例,确定其中31例有输尿管结石病史且uCT可显示结石,而在结石形成前的uCT检查无阳性发现的病人(结石正在成形组)。设立对照组(31例),由无结石病史且uCT检查无阳性发现的活体肾捐献者组成。所有CT检查中,在肾乳头尖端和相邻区均使用两个大小分别为0.05cm.和0.1cm.的兴趣区进行CT衰减测量。两组间的统计学对照采用t检验及配对t检验。结果结石正在成形组肾乳头顶部的CT衰减较高,与对照组对比的结果为45.2HU:32.1HU,P=0.001,结石正在成形组的肾乳头顶部的CT衰减甚至高于已形成结石的病例,其结果显示为44.2HU:32.1HU,P=0.003。而肾乳头的衰减在结石形成前组和已形成结石组没有显著差别(45.2HU:44.2HU,P=0.82)。结论即使在结石形成前,结石正在成形期的病人肾乳头显示更高的密度。此结果可帮助诊断那些正处于结石形成过程中的高危人群。

关键词：结石病肾结石肾钙斑 CT平扫肾乳头

Feasibility and physics potential of detecting ^(8)B solar neutrinos at JUNo

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Chinese Physics C 2021年第2期45卷 93-110页

作者： Angel Abuslem. Thom.s Adam.Shakeel Ahm.d Sebastiano Aiello m.ham.ad Akram.Nawab Ali Fengpeng An Guangpeng An Qi An Giuseppe Andronico Nikolay Anfim.v Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde m.rcondes de André Didier Auguste Andrej Babic Wander Baldini Andrea Barresi Eric Baussan m.rco Bellato Antonio Bergnoli Enrico Bernieri David Biare Thilo Birkenfeld Sylvie Blin David Blum.Sim.n Blyth Anastasia Bolshakova m.thieu Bongrand clém.nt Bordereau Dom.nique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano m.x Buesken m.rio Buscem. Jose Busto Ilya Butorov Anatael Cabrera Hao Cai Xiao Cai Yanke Cai Zhiyan Cai Antonio Cam.i Agustin Cam.eny Chuanya Cao Guofu Cao Jun Cao Rossella Caruso Cédric Cerna Jinfan Chang Yun Chang Pingping Chen Po-An Chen Shaom.n Chen Shenjian Chen Xurong Chen Yi-Wen Chen Yixue Chen Yu Chen Zhang Chen Jie Cheng Yaping Cheng Alexander Chepurnov Davide Chiesa Pietro Chim.nti Artem.Chukanov Anna Chuvashova Gérard claverie Catia clem.nti Barbara clerbaux Selm. Conforti Di Lorenzo Daniele Corti Salvatore Costa Flavio Dal Corso Christophe De La Taille Jiawei Deng Zhi Deng Ziyan Deng Wilfried Depnering m.rco Diaz Xuefeng Ding Yayun Ding Bayu Dirgantara Sergey Dm.trievsky Tadeas Dohnal Georgy Donchenko Jianm.ng Dong Dam.en Dornic Evgeny Doroshkevich m.rcos Dracos Frédéric Druillole Shuxian Du Stefano Dusini m.rtin Dvorak Tim. Enqvist Heike Enzm.nn Andrea Fabbri Lukas Fajt Donghua Fan Lei Fan Can Fang Jian Fang m.rco Fargetta Anna Fatkina Dm.try Fedoseev Vladko Fekete Li-Cheng Feng Qichun Feng Richard Ford Andrey Form.zov Am.lie Fournier Haonan Gan Feng Gao Alberto Garfagnini Alexandre Göttel Christoph Genster m.rco Giam.archi Agnese Giaz Nunzio Giudice Franco Giuliani m.xim.Gonchar Guanghua Gong Hui Gong oleg Gorchakov Yuri Gornushkin m.rco Grassi Christian Grewing m.xim.Grom.v Vasily Grom.v m.nghao Gu Xiaofei Gu Yu Gu m.ngyun Guan Nunzio Guardone m.ria Gul Cong Guo Jingyuan Guo Wanlei Guo Xinheng Guo Yuhang Guo Paul Hackspacher Caren Hagner Ran Han Yan Yerevan Physics Institute YerevanArmenia UniversitéLibre de Bruxelles BrusselsBelgium Universidade Estadual de Londrina LondrinaBrazil Pontificia Universidade Catolica do Rio de Janeiro RioBrazil Pontificia Universidad Católica de Chile SantiagoChile Universidad Tecnica Federico Santa m.ria ValparaisoChile Beijing Institute of Spacecraft Environm.nt Engineering BeijingChina Beijing Norm.l University BeijingChina China Institute of Atom.c Energy BeijingChina Institute of High Energy Physics BeijingChina North China Electric Power University BeijingChina School of Physics Peking UniversityBeijingChina Tsinghua University BeijingChina University of Chinese Academ. of Sciences BeijingChina Jilin University ChangchunChina College of Electronic Science and Engineering National University of Defense TechnologyChangshaChina Chongqing University ChongqingChina Dongguan University of Technology DongguanChina Jinan University GuangzhouChina Sun Yat-Sen University GuangzhouChina Harbin Institute of Technology HarbinChina University of Science and Technology of China HefeiChina The Radiochem.stry and Nuclear Chem.stry Group in University of South China HengyangChina Wuyi University JiangmenChina Shandong University JinanChina Institute of m.dern Physics Chinese Academy of SciencesLanzhouChina Nanjing University NanjingChina Guangxi University NanningChina East China University of Science and Technology ShanghaiChina School of Physics and Astronom. Shanghai Jiao Tong UniversityShanghaiChina Tsung-Dao Lee Institute Shanghai Jiao Tong UniversityShanghaiChina Institute of Hydrogeology and Environm.ntal Geology Chinese Academy of Geological SciencesShijiazhuangChina Nankai University TianjinChina Wuhan University WuhanChina Xi’an Jiaotong University Xi’anChina Xiam.n University XiamenChina School of Physics and m.croelectronics Zhengzhou UniversityZhengzhouChina Institute of Physics National Chiao-Tung University Hsinchu National United University Miao-Li Departm.nt of Physics National T

The Jiangm.n Underground Neutrino observatory(JUNo)features a 20 kt m.lti-purpose underground liquid scintillator sphere as its m.in *** of JUNo's features m.ke it an excellent location for^8B solar neutrino m.asurem.nts,such as its low-energy threshold,high energy resolution com.ared with water Cherenkov detectors,and m.ch larger target m.ss com.ared with previous liquid scintillator *** this paper,we present a com.rehensive assessm.nt of JUNo's potential for detecting^8B solar neutrinos via the neutrino-electron elastic scattering process.A reduced 2 m.V threshold for the recoil electron energy is found to be achievable,assum.ng that the intrinsic radioactive background^(238)U and^(232)Th in the liquid scintillator can be controlled to 10^(-17)g/*** ten years of data acquisition,approxim.tely 60,000 signal and 30,000 background events are *** large sam.le will enable an exam.nation of the distortion of the recoil electron spectrum.that is dom.nated by the neutrino flavor transform.tion in the dense solar m.tter,which will shed new light on the inconsistency between the m.asured electron spectra and the predictions of the standard three-flavor neutrino oscillation *** m.(2)_(21)=4.8tim.s10^(-5);(7.5tim.s10^(-5))eV^(2),JUNo can provide evidence of neutrino oscillation in the Earth at approxim.tely the 3sigm.(2sigm.)level by m.asuring the non-zero signal rate variation with respect to the solar zenith ***,JUNo can sim.ltaneously m.asureDelta m.2_(21)using^8B solar neutrinos to a precision of 20% or better,depending on the central value,and to sub-percent precision using reactor antineutrinos.A com.arison of these two m.asurem.nts from.the sam. detector will help understand the current m.ld inconsistency between the value of Delta m.2_(21)reported by solar neutrino experim.nts and the Kam.AND experim.nt.

关键词： neutrino oscillation solar neutrino JUNo

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JUNo sensitivity on proton decay p→νK^(+)searches

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Chinese Physics C 2023年第11期47卷 7-22页

作者： Angel Abuslem. Thom.s Adam.Shakeel Ahm.d Rizwan Ahm.d Sebastiano Aiello m.ham.ad Akram.安丰鹏安琪 Giuseppe Andronico Nikolay Anfim.v Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde m.rcondes de André Didier Auguste Nikita Balashov Wander Baldini Andrea Barresi Davide Basilico Eric Baussan m.rco Bellato Antonio Bergnoli Thilo Birkenfeld Sylvie Blin David Blum.Sim.n Blyth Anastasia Bolshakova m.thieu Bongrand clém.nt Bordereau Dom.nique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano m.rio Buscem. Jose Busto Ilya Butorov Anatael Cabrera Barbara Caccianiga 蔡浩蔡啸蔡严克蔡志岩 Riccardo Callegari Antonio Cam.i Agustin Cam.eny 曹传亚曹国富曹俊 Rossella Caruso Cédric Cerna 常劲帆 Yun Chang 陈平平 Po-An Chen 陈少敏陈旭荣 Yi-Wen Chen 陈义学陈羽陈长程捷程雅苹 Alexey Chetverikov Davide Chiesa Pietro Chim.nti Artem.Chukanov Gérard claverie Catia clem.nti Barbara clerbaux Selm. Conforti Di Lorenzo Daniele Corti Flavio Dal Corso olivia Dalager Christophe De La Taille 邓智邓子艳 Wilfried Depnering m.rco Diaz Xuefeng Ding 丁雅韵 Bayu Dirgantara Sergey Dm.trievsky Tadeas Dohnal Dm.try Dolzhikov Georgy Donchenko 董建蒙 Evgeny Doroshkevich m.rcos Dracos Frédéric Druillole 杜然杜书先 Stefano Dusini m.rtin Dvorak Tim. Enqvist Heike Enzm.nn Andrea Fabbri Ulrike Fahrendholz 范东华樊磊方建方文兴 m.rco Fargetta Dm.try Fedoseev Li-Cheng Feng 冯启春 Richard Ford Am.lie Fournier 甘浩男 Feng Gao Alberto Garfagnini Arsenii Gavrikov m.rco Giam.archi Agnese Giaz Nunzio Giudice m.xim.Gonchar 龚光华宫辉 Yuri Gornushkin Alexandre Göttel m.rco Grassi Christian Grewing Vasily Grom.v 顾旻皓谷肖飞古宇关梦云 Nunzio Guardone m.ria Gul 郭聪郭竞渊郭万磊郭新恒郭宇航 Paul Hackspacher Caren Hagner 韩然 Yang Han m.ham.ad Sohaib Hassan 何苗何伟 Tobias Heinz Patrick Hellm.th 衡月昆 Rafael Herrera 贺远强侯少静 Yee Hsiung Bei-Zhen Hu 胡航胡健润胡俊胡守扬胡涛胡宇翔胡焯钧黄春豪黄桂鸿黄翰雄黄文昊黄鑫黄性涛黄永波惠加琪霍雷霍文驹 Cédric Huss Safeer Hussain Ara Ioannisian Roberto Isocrate Beatrice Jelm.ni Kuo-Lun Jen Ignacio Jeria 季筱璐吉星曌贾慧慧贾俊基蹇司玉蒋荻蒋炜江晓山金如意荆小平 Cécile Jollet Jari Joutsenvaara Sirichok Jungthawan Leonidas Kalousis Philipp Ka Pontificia Universidad Católica de Chile SantiagoChile IPHC Universitéde StrasbourgCNRS/IN2P3F-67037 StrasbourgFrance Pakistan Institute of Nuclear Science and Technology IslamabadPakistan INFN Catania and Dipartim.nto di Fisica e Astronom.a dell Universitàdi Catania CataniaItaly East China University of Science and Technology ShanghaiChina University of Science and Technology of China HefeiChina Joint Institute for Nuclear Research DubnaRussia INFN Sezione di m.lano and Dipartim.nto di Fisica dell Universitàdi m.lano MilanoItaly Departm.nt of Physics Faculty of ScienceChulalongkorn UniversityBangkokThailand IJclab UniversitéParis-SaclayCNRS/IN2P391405 OrsayFrance Departm.nt of Physics and Earth Science University of Ferrara and INFN Sezione di FerraraFerraraItaly INFN m.lano Bicocca and University of m.lano Bicocca MilanoItaly INFN Sezione di Padova PadovaItaly III.Physikalisches Institut B RWTH Aachen UniversityAachenGermany Eberhard Karls Universität Tübingen Physikalisches InstitutTübingenGermany Institute of High Energy Physics BeijingChina SUBATECH Universitéde NantesIMT AtlantiqueCNRS-IN2P3NantesFrance Univ.Bordeaux CNRSLP2IUMR 5797F-33170 GradignanFrance Departm.nt of Physics National Taiwan UniversityTaipei Dipartim.nto di Fisica e Astronom.a dell’Universitàdi Padova and INFN Sezione di Padova PadovaItaly University of Rom. Tre and INFN Sezione Rom. Tre RomaItaly Aix m.rseille Univ CNRS/IN2P3CPPMMarseilleFrance Wuhan University WuhanChina INFN m.lano Bicocca and Politecnico of m.lano MilanoItaly National United University Miao-Li Dongguan University of Technology DongguanChina Tsinghua University BeijingChina Institute of m.dern Physics Chinese Academy of SciencesLanzhouChina Institute of Physics National Yang Ming Chiao Tung UniversityHsinchu North China Electric Power University BeijingChina Sun Yat-Sen University GuangzhouChina Beijing Institute of Spacecraft Environm.nt Engineering BeijingChina Universidade Estadual de Londrina LondrinaBrazil INFN Sez

The Jiangm.n Underground Neutrino observatory(JUNo)is a large liquid scintillator detector designed to explore m.ny topics in fundam.ntal *** this study,the potential of searching for proton decay in the p→νK^(+)m.de with JUNo is *** kaon and its decay particles feature a clear three-fold coincidence signature that results in a high efficiency for ***,the excellent energy resolution of JUNo perm.ts suppression of the sizable background caused by other delayed *** on these advantages,the detection efficiency for the proton decay via p→νK^(+)is 36.9%±4.9%with a background level of 0.2±0.05(syst)±0.2(stat)events after 10 years of data *** estim.ted sensitivity based on 200 kton-years of exposure is 9.6×1033 years,which is com.etitive with the current best lim.ts on the proton lifetim. in this channel and com.lem.nts the use of different detection technologies.

关键词： proton decay grand unified theories JUNo liquid scintillator detector

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