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Urea breath test for Helicobacter pylori infection in adult dyspeptic patients: A meta-analysis of diagnostic test accuracy

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World Journal of Gastroenterology 2024年第6期30卷 579-598页

作者： Fabian Fellipe Bueno Lemos Caroline Tianeze de Castro Marcel Silva Luz Gabriel Reis Rocha Gabriel Lima Correa Santos Luís Guilherme de Oliveira Silva Mariana Santos Calmon cláudio Lima Souza Ana Carla Zarpelon-Schutz Kádima Nayara Teixeira Dulciene Maria de Magalhães Queiroz Fabrício Freire de melo Instituto Multidisciplinar em Saúde Universidade Federal da BahiaVitória da Conquista 45029-094BahiaBrazil Instituto de Saúde Coletiva Universidade Federal da BahiaSalvador 40110040BahiaBrazil Campus Toledo Universidade Federal do ParanáToledo 85919-899ParanáBrazil Laboratory of Research in Bacteriology UFMGBelo Horizonte 30130-100Minas GeraisBrazil

BACKGROUND Helicobacter pylori(***)infection has been well-established as a significant risk factor for several gastrointestinal *** urea breath test(UBT)has emerged as a leading non-invasive method for detecting *** numerous studies confirming its substantial accuracy,the reliability of UBT results is often compromised by inherent *** findings underscore the need for a rigorous statistical synthesis to clarify and reconcile the diagnostic accuracy of the UBT for the diagnosis of *** *** To determine and compare the diagnostic accuracy of 13C-UBT and 14C-UBT for *** infection in adult patients with *** We conducted an independent search of the PubMed/MEDLINE,EMBASE,and Cochrane Central databases until April *** search included diagnostic accuracy studies that evaluated at least one of the index tests(^(13)C-UBT or ^(14)C-UBT)against a reference *** used the QUADAS-2 tool to assess the methodo-logical quality of the *** utilized the bivariate random-effects model to calculate sensitivity,specificity,positive and negative test likelihood ratios(LR+and LR-),as well as the diagnostic odds ratio(DOR),and their 95%confidence *** conducted subgroup analyses based on urea dosing,time after urea administration,and assessment *** investigate a possible threshold effect,we conducted Spearman correlation analysis,and we generated summary receiver operating characteristic(SROC)curves to assess ***,we visually inspected a funnel plot and used Egger’s test to evaluate publication *** both as reliable diagnostic tools in clinical *** In summary,our study has demonstrated that ^(13)C-UBT has been found to outperform the ^(14)C-UBT,making it the preferred diagnostic ***,our results emphasize the significance of carefully considering urea dosage,assessment timing,and measurement techniques for both tests to enh

关键词： Helicobacter pylori Urea breath test Diagnosis Diagnostic test accuracy Meta-analysis

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5-Bromo-2'-deoxyuridine labeling:historical perspectives,factors infiuencing the detection,toxicity,and its implications in the neurogenesis

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Neural Regeneration Research 2024年第2期19卷 302-308页

作者： Joaquín Martí-clúa Unidad de Citología e Histología.Departament de Biologia Cel·lular de Fisiologia i d’Immunologia.Facultad de Biociencias.Institut de Neurociències.Universidad Autónoma de Barcelona08193 BellaterraBarcelonaSpain

The halopyrimidine 5-bromo-2′-deoxyuridine(BrdU)is an exogenous marker of DNA *** the introduction of monoclonal antibodies against BrdU,an increasing number of methodologies have been used for the immunodetection of this synthesized bromine-tagged base analogue into replicating *** labeling is widely used for identifying neuron precursors and following their fate during the embryonic,perinatal,and adult neurogenesis in a variety of vertebrate species including birds,reptiles,and *** to BrdU toxicity,its incorporation into replicating DNA presents adverse consequences on the generation,survival,and settled patterns of *** may lead to false results and misinterpretation in the identification of proliferative *** this review,I will indicate the detrimental effects of this nucleoside during the development of the central nervous system,as well as the reliability of BrdU labeling to detect proliferating ***,it will show factors influencing BrdU immunodetection and the contribution of this nucleoside to the study of prenatal,perinatal,and adult *** adult neurogenesis will also be *** is my hope that this review serves as a reference for those researchers who focused on detecting cells that are in the synthetic phase of the cell cycle.

关键词： 5-bromo-2′-deoxyuridine adult neurogenesis human adult neurogenesis labeling pitfalls prenatal neurogenesis proliferation S-phase suturing S-phase toxicity

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Five Year Follow up after Surgical Treatment of Type 2 Diabetes with Laparoscopic Sleeve Gastrectomy Associated with a Duodenal Ileal Interposition

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Surgical Science 2024年第6期15卷 396-408页

作者： Augusto cláudio de Almeida Tinoco Matheus Paula da Silva Netto Henrique Benedito Aureo Ludovico DePaula Luciana Janene El-Kadre Department of Digestive Surgery Hospital So Jos do Ava Itaperuna Brazil Department of Metabolic and Obesity Surgery Hospital So Jos do Ava Itaperuna Brazil

Introduction: Type 2 diabetes mellitus (T2D) is a chronic disease, primarily caused by a combination of defective insulin secretion and the inability of insulin-sensitive tissues to respond to insulin. Laparoscopic sleeve gastrectomy associated with duodenal ileal interposition (SGDII) has been shown to be a feasible treatment option for patients with T2D, as it provides improvement and control of glycemia, dyslipidemia and arterial hypertension. The aim of this study was to evaluate the mid and long-term results of SGDII for the treatment of diabetic patients, considering diabetic remission, weight loss and postoperative complications. Materials and Methods: Retrospective study with 96 patients with T2D submitted to SGDII, between 2010 and 2016. The glycated hemoglobin (HbA1c) value Results: Sixty-one patients (62.8%) were male, and 36 patients (37.2%) were female. The average age was 50.9 years. Median BMI was 33.43 kg/m2. The incidence of major postoperative complications in the first 30 days was 2.1%, with no mortality. Dyslipidemia control was sustained, after five years, in 62% of the patients. The five years follow-up demonstrated that 80% of patients had T2D remission at one year, 74.5% at three years and 61.8% at five years. Univariate analysis demonstrated that preoperative values of HbA1c and BMI, preoperative use of insulin, gender, and 30-day complication were not predictors of remission at all study intervals. The average duration of the disease was nine years and the mean glycated hemoglobin before surgery was 8.95%. Conclusion: SGDII resulted in good glycemic control at 5-years follow-up and represents a valid alternative for the treatment of T2D.

关键词： Diabetes Surgery Metabolic Syndrome Dyslipidemia Ileal Interposition Metabolic Surgery Bariatric Surgery Obesity

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家用制冷电子膨胀阀流量特性的研究

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家电科技 2020年第4期 12-13页

作者： Fernando T. Knabben cláudio melo Christian J.L. Hermes

毛细管是家用制冷应用中最常用的膨胀装置。毛细管是具有很小内径的长管,主要通过摩擦阻力来降低压力。这种装置的主要缺点是其几何形状固定,因此,一旦确定尺寸,毛细管在非设计条件下可能无法正常工作,导致冰箱的性能系数降低,能耗增加... 详细信息

毛细管是家用制冷应用中最常用的膨胀装置。毛细管是具有很小内径的长管,主要通过摩擦阻力来降低压力。这种装置的主要缺点是其几何形状固定,因此,一旦确定尺寸,毛细管在非设计条件下可能无法正常工作,导致冰箱的性能系数降低,能耗增加。全球能耗标准IEC62552在2015年进行了修订,冰箱的性能要考虑两种环境温度(即32℃和16℃)。因此会出现这类情况,即单速压缩机和毛细管的系统在32℃环境下良好运行,但在16℃环境下可能无法令人满意。替代方案是使用可变膨胀装置,例如,使用能够根据热负荷来调节制冷量的电子膨胀阀(EEV)。

关键词：能耗标准电子膨胀阀流量特性替代方案几何形状环境温度毛细管制冷量

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Selenium Differentially Regulates Flavonoid Accumulation and Antioxidant Capacities in Sprouts of Twenty Diverse Mungbean(Vigna radiata(L.)Wilczek)Genotypes

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Phyton-International Journal of Experimental Botany 2024年第3期93卷 611-625页

作者： Fenglan Zhao Jizhi Jin Meng Yang Franklin Eduardo melo Santiago Jianping Xue Li Xu Yongbo Duan Anhui Provincial Engineering Laboratory for Efficient Utilization of Featured Resource Plants College of Life SciencesHuaibei Normal UniversityHuaibei235000China Department of Soil Science Federal Institute of PiauiUruçuíPiauí64860-000Brazil The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine Guiyang550003China

Seed germination with selenium(Se)is promising for producing Se-biofortiﬁed ***(Vigna radiata(L.)Wilczek)sprout is freshly eaten as a salad dressed with sauce,making it superior for Se biofortiﬁ*** the Se safety range for the human body is extremely narrow,it is imperative to evaluate the genotypic responses of mungbean sprouts to *** study evaluated the Se enrichment capacity and interaction withﬂavonoids and antioxidant systems in sprouts of 20 mungbean *** treatment was done by immersing mung-bean seeds in 20μM sodium selenite solution for 8 ***,the biomass,Se amounts,ﬂavonoid(particularly vitexin and isovitexin)contents,antioxidant capacity,and key biosynthetic gene expressions were *** Se content was 2.0-7.0μg g^(-1) DW among the 20 mungbean *** treatment differentially affected the biomass,totalﬂavonoid,vitexin,isovitexin,antioxidant enzyme activities,and antioxidant capacities of the mungbean *** germplasms showed increased biomass(pclusion,mungbean sprouts could be a useful Se-biofortiﬁed food,but the Se enrichment capacity and nutritional response must be determined for each germplasm before commercialization.

关键词： Antioxidant capacity gene expression genotypic variation isovitexin vitexin selenium

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Pollen analysis reveals the effects of uncovered interactions,pollen-carrying structures,and pollinator sex on the structure of wild bee-plant networks

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Insect Science 2024年第3期31卷 971-988页

作者： clément Tourbez Carmelo Gómez-Martínez MiguelÁngel Gonzalez-Estévez Amparo Lazaro Mediterranean Institute for Advanced Studies(UIB-CSIC) Global Change Research GroupEsporlesBalearic IslandsSpain Department of Biology Ecology AreaUniversity of the Balearic/slandsPalmaSpain

Pollination networks are increasingly used to model the complexity of interactions between pollinators and flowering plants in *** methods exist to sample these interactions,with direct observations of plant-pollinator contacts in the field being by far the most *** the identification of pollen carried by pollinators allows uncovering interactions and increasing sample sizes,the methods used to build pollen-transport networks are variable and their effect on network structure remains *** understand how interaction sampling influences the structure of networks,we analyzed the pollen found on wild bees from eight communities across Mallorca Island and investigated the differences in pollen loads between bee body parts(scopa ***)and *** then assessed how these differences,as well as the uncovered interactions not detected in the field,influenced the structure of wild bee-plant *** identified a higher quantity and diversity of pollen in the scopa than in the rest of the female body,but these differences did not lead to differences in structure between plant-pollination(excluding scopa pollen)and bee-feeding interaction(including scopa pollen)***,networks built with pollen data were richer in plant species and interactions and showed lower modularity and specialization(H2'),and higher nestedness than visitation networks based on field *** interactions with plants were stronger compared to those of males,although not ***,females were more generalist(low d')and tended to be more central in interaction networks,indicating their more key role structuring pollination networks in comparison to *** study highlights the importance of palynological data to increase the resolution of networks,as well as to understand important ecological questions such as the differences between plant-pollination and bee-feeding interaction networks,and the role of sexes in pollination.

关键词： palynology pollen-transport networks pollination role of bee sexes sampling methodology visitation networks

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Response to Commentary by Dr. Matthew J. clarkson on

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Journal of Sport and Health Science 2024年第5期13卷 670-671页

作者： Hugo de Luca Corrêa Lysleine Alves Deus Dahan da Cunha Nascimento Nicholas Rolnick Rodrigo Vanerson Passos Neves Andrea Lucena Reis Thais Branquinho de Araújo Carmen Tzanno-Martins Fernanda Silveira Tavares Luiz Sinésio Silva Neto cláudio Avelino Rodrigues Santos Paolo Lucas Rodrigues-Silva Fernando Honorato Souza Vitória Marra da Motta Vilalva Mestrinho Rafael Lavarini dos Santos Rosangela Vieira Andrade Jonato Prestes Thiago dos Santos Rosa Post-graduate Program of Physical Education Catholic University of BrasıliaBrasılia 71966-700Brazil The Human Performance Mechanic Lehman CollegeNew YorkNY 10011USA clinical Group Home Dialysis Center and Renalclass Sao Paulo 01239-040Brazil Department of Medicine Catholic University of BrasıliaBrasılia 71966-700Brazil Faculty of Medicine Federal University of TocantinsTocantins 77001-090Brazil Embrapa Genetic Resources and Biotechnology Brasılia 70770-917Brazil g Graduate Program of Genomic Sciences and Biotechnology Brasılia 71966-700Brazil

Dear editor:We sincerely thank Matthew *** for his insightful commentary1 on our recent publication in the Journal of Sport and Health Science.2 clarkson's pioneering work in the development and application of blood flow restriction (BFR) exercise protocols has undeniably laid the groundwork for subsequent investigations in this field,including our own.(3-6)His commentary not only highlights the relevance and timeliness of our study but also offers valuable perspectives on refining safety considerations for intradialytic BFR exercise among hemodialysis patients.

关键词： patients application flow

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Semantic Segmentation of the Intertidal Zone of an Estuary—In Search of the Best Solution

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Journal of Geoscience and Environment Protection 2024年第7期12卷 1-13页

作者： Maria da Conceição Proença Ricardo Nogueira Mendes Ricardo melo Marine and Environmental Sciences Centre (MARE-ULisboa) & ArNet Lisbon Portugal Department of Physics Faculty of Sciences University of Lisbon Lisbon Portugal Department of Animal Biology Faculty of Sciences University of Lisbon Lisbon Portugal Department of Plant Biology Faculty of Sciences University of Lisbon Lisbon Portugal

An aerial photographic coverage acquired on two consecutive days in October 2021 with a ground resolution of 20 cm and a spectral resolution of 4 bands (red, green, blue and near infrared), allowed to distinguish most of the classes of interest present in the intertidal zone of the Sado estuary. We explored the possibilities of thematic classification in the powerful and complex software ArcGIS Pro;we presented the methodology used in a detailed way that allows others with minimal knowledge of GIS to reproduce the classification process without having to decipher the specifics of the software. The classification implemented used ground truth from four classes related to the macro-occupations of the area. In a first phase we explore the standard algorithms with object-based capabilities, like K-Nearest Neighbor, Random Trees Forest and Support Vector Machine, and in a second phase we proceed to test three deep learning classifiers that provide semantic segmentation: a U-Net configuration, a Pyramid Scene Parsing Network and DeepLabV3. The resulting classifications were quantitatively evaluated with a set of 500 control points in a test area of 37,500 × 12,500 pixels, using confusion matrices and resorting to Cohen’s kappa statistic and the concept of global accuracy, achieving a Kappa in the range [0.72, 0.81] and a global accuracy between 88.9% and 92.9%;the option U-Net had the most interesting results. This work establishes a methodology to provide a baseline for assessing future changes in the distribution of Sado estuarine habitats, which can be replicated in other wetland ecosystems for conservation and management purposes.

关键词： Estuary Intertidal Zone ArcGIS Pro Segmentation Global Changes

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Variation of Morpho-Agronomic and Biomass Quality Traits in Elephant Grass for Energy Purposes According to Nitrogen Levels

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American Journal of Plant Sciences 2015年第11期6卷 1685-1696页

作者： Erik da Silva Oliveira Rogério Figueiredo Daher Niraldo José Ponciano Geraldo de Amaral Gravina José Augusto de Almeida Sant’ana Romildo Domingos Gottardo Bruna Rafaela da Silva Menezes Paulo Marcelo de Souza cláudio Luiz melo de Souza Veronica Brito da Silva Avelino dos Santos Rocha Antonio Alonso Cecon Novo Universidade Estadual do Norte Fluminense Darcy Ribeiro Campos dos GoytacazesRJBrazil Instituto Federal do Espírito Santo Campus of AlegreAlegreESBrazil Universidade Federal Rural do Rio de Janeiro SeropédicaRJBrazil

Elephant grass is a tropical forage plant widely spread in Brazil, used mainly in the livestock sector and in cattle feeding. Because of its high productivity and photosynthetic capacity, this culture has also been considered an alternative source of renewable energy. Six clones of elephant grass (Pennisetum purpureum Schum.) were evaluated under five levels of nitrogen fertilization (100, 200, 400, 800, and 1600 kg·N·ha-1), in a randomized-block design with a split-plot arrangement with three replicates, from April 2010 to December 2012, in the city of Campos dos Goytacazes— RJ, Brazil. The objective was to obtain estimates of variation in morpho-agronomic traits and biomass quality. We observed that genotypes Cameroon-Piracicaba and Gua?u I/Z2 have great potential to be used, with maximum dry matter yields of 60.97 and 44.10 t·ha-1 per cut for energy purposes among the studied genotypes.

关键词： Nitrogen Fertilization Alternative Energy Energy Biomass Dry Matter Yield Pennisetum purpureum Schum

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Measuring Cognitive and Psychosocial Accessibility to Modern Contraception: A Comprehensive Framework

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Health 2024年第7期16卷 578-591页

作者： Lonkila Moussa Zan clémentine Rossier Caroline Moreau INSD/ISSP Universit Joseph KI-ZERBO Ouagadougou Burkina Faso IDESO University of Geneva Geneva Switzerland Gates Institute Johns Hopkins University Baltimore United States

Nowadays, more than ever, the improvement of access to family planning (FP) has become an international goal. What constitutes access to FP? Current human rights-based contraceptive guidelines indicate that access begins as soon as women or couples express a desire to avoid pregnancy and their risk of unintended pregnancy is established. However, few studies have sought to define and measure cognitive and psychosocial access to contraception. To propose a comprehensive framework for the cognitive and psychosocial accessibility of contraception, we critically analyzed the literature on attitudes toward FP. The main dimensions that emerged were knowledge about FP, fear of side effects, approval of contraception, and contraceptive agency. We then identified and adjusted some questions that can capture these dimensions more comprehensively. As a result, we developed a questionnaire module comprising 15 questions, which was integrated into the 6th round of the PMA2020 survey in Burkina Faso in 2019. This research highlighted that previous studies have collected separate dimensions of contraceptive access, and the psychosocial dimension tended to be neglected. Our results demonstrate that it is possible to collect comprehensive data on cognitive and psychosocial dimensions of access to family planning.

关键词： Cognitive Dimensions Psychosocial Dimensions Contraception Intention To Use Side Effects

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