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减肥期间低糖负荷饮食对静息能量消耗和心脏病危险因素的作用

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世界核心医学期刊文摘（心脏病学分册） 2005年第4期1卷 21-21页

作者： pereira M. A. Swain J. Goldfine A. B. D. S. Ludwig 王亭忠 Department of Medicine Children's Hospital 300 Longwood Ave Boston MA 02115 United States Dr.

Context: Weight loss elicits physiological adaptations relating to energy inta ke and expenditure that antagonize ongoing weight loss. Objective: To test wheth er dietary composition affects the physiological adaptations to weight loss, as assessed by resting energy expenditure. Design, Study, and Participants: A rando mized paralleldesign study of 39 over-weight or obese young adults aged 18 to 4 0 years who received an energy-restricted diet, either low-glycemic load or lo w-fat. Participants were studied in the General clinical Research Centers of th e Brigham and Women’s Hospital and the Children’s Hospital, Boston, Mass, befo re and after 10%weightless. The study was conducted from January 4,2001, to May 6, 2003. Main Outcome Measures: Resting energy expenditure measured in the fast ing state by indirect calorimetry, body composition by dual-energy X-ray absor ptiometry, cardiovascular disease risk factors, and self-reported hunger. Resul ts: Resting energy expenditure decreased less with the low-glycemic load diet t han with the low-fat diet, expressed in absolute terms(mean[SE], 96 [24] vs 176 [27] kcal/d; P=.04) or as a proportion(5.9%[1.5%] vs 10.6%[1.7%]; P=.05). Pa rticipants receiving the low-glycemic load diet reported less hunger than those receiving the low-fat diet(P=.04). Insulin resistance(P=.01), serum triglyceri des(P=.01), C-reac-tive protein(P=.03), and blood pressure(P=.07 for both syst olic and diastolic) improved more with the low-gly-cemic load diet. Changes in body composition (fat and lean mass) in both groups were very similar(P=.85 and P=.45, respectively). Conclusions: Changes in dietary composition within prevai ling norms can affect physiological adaptations that defend body weight. Reducti on in glycemic load may aid in the prevention or treatment of obesity, cardiovas cular disease, and diabetes mellitus.

关键词：糖负荷静息能量消耗低脂饮食生理性代偿反应饥饿感空腹状态胰岛素抵抗临床研究中心儿童医院心血管疾病

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Cell Replication and Angiogenesis in Central Nervous System Tumors and Their Relationship with the Expression of Tissue Prolactin and Hyperprolactinemia

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Where Are the Bromeliads? A Study on Different Trails in the Ecological Reserve of Guapiaçu, RJ

Open Journal of Pathology（病理学期刊） 2012年第3期

作者： Denise M. D. Abech Júlia F. S. pereira-Lima Carolina G. S. Leães Rosalva T. Meurer Lígia M. Barbosa-Coutinho Nelson P. Ferreira Miriam C. Oliveira

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Effects of matrine and oxymatrine on catalytic activity of cytochrome P450s in rats

Agricultural Sciences（农业科学） 2023年第2期

作者： Johnatan Jair de Paula Marchiori Vinicius de Souza Oliveira Gilcéa Teixeira Fontana Boone Luan Luciano dos Santos pereira Natália Cristina Barbosa de Moura Ana Beatriz Mamedes Piffer Anderson Mathias Holtz Lusiane de Sousa Ferreira Raquel Cetto Sampaio

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Effects of matrine and oxymatrine on catalytic activity of c...

The Faces of Fungi database:fungal names linked with morphology,phylogeny and human impacts

2010年广东省药师周大会

作者： Fang Yuan1a,Jie Chen 2a,Wen-jin Wu 3,Su-zhen Chen 1,Xue-ding Wang 1 and Min Huang 1 1 Institute of clinical Pharmacology,School of Pharmaceutical Sciences,Sun Yat-sen University,74 Zhongshan Road II,Guangzhou 510080,P.R.China,and 2 Department of Pharmacy,the First Affiliated Hospital,Sun Yat-sen University,58 Zhongshan Road II,Guangzhou 510080,China,and 3 Institution of Chinese Medical Science,University of Macau,Av.Padre Tomás pereira S.J.,Taipa,Macao,P.R.China.

Matrine and oxymatrine are the major bioactive compounds extracted from the root of Sophorae flavescens Ait,which have been widely used in traditional Chinese *** objective of the study was to investigate the effects of matrine or oxymatrine on hepatic cytochrome P450 (CYP450) and the underlying molecular *** (15,75 and 150 mg kg-1 ) or oxymatrine (36,180 and 360 mg kg-1) had been administrated to rats for 14 days and the activities of CYP450 were measured by the quantication of the metabolites from multiple CYP450 probe substrates,using validated liquid chromatography coupled with liquid chromatography-tandem mass spectrometry detection (LC-MS/MS) and High Performance Liquid Chromatography methods (HPLC).The mRNA and protein expression level of CYPs were determined by quantitative real-time reverse-transcription polymerase chain reaction and western blotting analysis *** between matrine or oxymatrine and human constitutive androstane (CAR),pregnane X receptor (PXR) were evaluated by means of reporter gene assay in CV-1 *** study showed that matrine and oxymatrine signicantly induced the activity and gene expression of CYP2B1 in a dose-dependent manner;Matrine (150 mg kg-1) slightly induced the mRNA and protein expression of CYP2E1 and mildly inhibited the mRNA and protein expression of CYP3A1 in *** or oxymatrine could activate human CAR and induce the CYP2B reporter construct in CV-1 *** results revealed that matrine and oxymatrine can induce the activity and expression of CYP2B1/2 in rats,and the underlying mechanism may be related to the activation of CAR.

关键词： Matrine Oxymatrine cytochrome P450 CYP2B1/2 induction.

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Fungal Diversity 2015年第5期74卷 3-18页

作者： Subashini C.Jayasiri Kevin D.Hyde Hiran A.Ariyawansa Jayarama Bhat Bart Buyck Lei Cai Yu-Cheng Dai Kamel A.Abd-Elsalam Damien Ertz Iman Hidayat Rajesh Jeewon E.B.Gareth Jones Ali H.Bahkali Samantha C.Karunarathna Jian-Kui Liu J.Jennifer Luangsa-ard H.Thorsten Lumbsch Sajeewa S.N.Maharachchikumbura Eric H.C.McKenzie Jean-Marc Moncalvo Masoomeh Ghobad-Nejhad Henrik Nilsson Ka-Lai Pang Olinto L.pereira Alan J.L.Phillips Olivier Raspé Adam W.Rollins Andrea I.Romero Javier Etayo Faruk Selçuk Steven L.Stephenson Satinee Suetrong Joanne E.Taylor clement K.M.Tsui Alfredo Vizzini Mohamed A.Abdel-Wahab Ting-Chi Wen Saranyaphat Boonmee Dong Qin Dai Dinushani A.Daranagama Asha J.Dissanayake Anusha H.Ekanayaka S.C.Fryar Sinang Hongsanan Ruvishika S.Jayawardena Wen-Jing Li Rekhani H.Perera R.Phookamsak Nimali Ide Silva Kasun M.T.hambugala Qing Tian Nalin N.Wijayawardene Rui-Lin Zhao Qi Zhao Ji-Chuan Kang Itthayakorn Promputtha Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand World Agro forestry Centre East and Central Asia Office 132 Lanhei RoadKunming 650201China Botany and Microbiology Department College of ScienceKing Saud UniversityRiyadh 1145Saudi Arabia Guizhou Key Laboratory of Agricultural Biotechnology Guizhou Academy of Agricultural SciencesGuiyang 550006GuizhouChina No.128/1-J Azad Housing SocietyCurcaP.O.Goa Velha403108 GoaIndia Department of Botany Goa UniversityGoa 403206India Muséum National d’Histoire Naturelle Département Systématique et EvolutionCP 39ISYEBUMR 7205 CNRS MNHN UPMC EPHE12 Rue BuffonF-75005 ParisFrance State Key Laboratory of Mycology Institute of MicrobiologyChinese Academy of SciencesWest Beicheng RdBeijingChina Institute of Microbiology Beijing Forestry UniversityPO Box 61Beijing 100083China Plant Pathology Research Institute Agricultural Research Center(ARC)12619 GizaEgypt Botanic Garden Meise Department Bryophytes-Thallophytes(BT)Nieuwelaan 38B-1860 MeiseBelgium Fédération Wallonie-Bruxelles Direction Générale de l’Enseignement non obligatoire et de la Recherche scientifiqueRue A.Lavallée 11080 BruxellesBelgium Microbiology Division Research Center for BiologyIndonesian Institute of Sciences(LIPI)Jl.Raya Jakarta-Bogor KM 46Cibinong 16911West JavaIndonesia Department of Health Sciences Faculty of ScienceUniversity of MauritiusReduitMauritius Microbe Interaction Laboratory(BMIT) BIOTECNational Science and Technology Development Agency(NSTDA)113 Thailand Science ParkThanon PhahonyothinTombon Khlong NuengAmphoe Khlong LuangPathum Thani 12120Thailand Science&Education The Field Museum1400 S.Lake Shore DriveChicagoIL 60605USA Manaaki Whenua Landcare Research Private Bag 92170AucklandNew Zealand Department of Natural History Royal Ontario Museumand Department of Ecology and Evolutionary BiologyUniversity of Toronto100 Queen’s ParkTorontoON M5S2C6Canada Department of Biotechnology Iranian Research Organiza

Taxonomic names are key links between various databases that store information on different *** global fungal nomenclural and taxonomic databases(notably Index Fungorum,Species Fungorum and MycoBank)can be sourced to find taxonomic details about fungi,while DNA sequence data can be sourced from NCBI,EBI and UNITE *** the sequence data may be linked to a name,the quality of the metadata is variable and generally there is no corresponding link to images,descriptions or herbarium *** is generally no way to establish the accuracy of the names in these genomic databases,other than whether the submission is from a reputable *** tackle this problem,a new database(FacesofFungi),accessible at ***(FoF)has been *** fungal database allows deposition of taxonomic data,phenotypic details and other useful data,which will enhance our current taxonomic understanding and ultimately enable mycologists to gain better and updated insights into the current fungal classification *** addition,the database will also allow access to comprehensive metadata including descriptions of voucher and type *** database is user-friendly,providing links and easy access between taxonomic ranks,with the classification system based primarily on molecular data(from the literature and via updated web-based phylogenetic trees),and to a lesser extent on morphological data when molecular data are *** FoF species are not only linked to the closest phylogenetic representatives,but also relevant data is provided,wherever available,on various applied aspects,such as ecological,industrial,quarantine and chemical *** data include the three main fungal groups(Ascomycota,Basidiomycota,Basal fungi)and fungus-like *** FoF webpage is an output funded by the Mushroom Research Foundation which is an NGO with seven directors with mycological *** webpage has 76 curators,and with the help of these s

关键词： classification Database Faces of Fungi Fungi Phylogeny Taxonomy

急性缺血性脑卒中血管内治疗流程和时间及其对治疗效果的影响分析:SWIFT PRIME随机对照试验的结果

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国际医学放射学杂志 2016年第4期 442-442页

作者： M.Goyal A.P.Jadhav A.Bonafe H.Diener V.M.pereira E.Levy 戴群瑶 Departments of Radiology and clinical Neuro-sciences University of Calgary

摘要目的研究急性缺血性脑卒中病人Solitaire支架机械取栓作为急性缺血性梗死(AIS)血管内主要治疗(SWIFT PRIME)试验中功能独立性和再灌注时间的关系,一组病人进行联合血管内治疗和静脉组织纤溶酶原激活物(t PA)治疗,另外一组进行单纯t... 详细信息

摘要目的研究急性缺血性脑卒中病人Solitaire支架机械取栓作为急性缺血性梗死(AIS)血管内主要治疗(SWIFT PRIME)试验中功能独立性和再灌注时间的关系,一组病人进行联合血管内治疗和静脉组织纤溶酶原激活物(t PA)治疗,另外一组进行单纯t PA治疗。研究影响不连续步骤间隔时间的变量。材料与方法分析SWIFT PRIME试验的

关键词：急性缺血性脑卒中再灌注血管内

Protective Properties in Hymenaea martiana Hayne against Multi-drug-resistant Staphylococcus aureus

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Veterinary Science Research 2020年第2期2卷 16-23页

作者： Dielson da Silva Vieira Tânia Maria Sarmento da Silva Timothy AHackett Marianade Barros Weslen Fabrício Pires Teixeira Juliana Campos pereira Diniz Pedro HenriqueGorni Sanely Lourenço da Costa Maria Aparecida Scatamburlo Moreira MateusMatiuzzi da Costa Francisco Leydson Formiga Feitosa São Paulo State University“Júlio de Mesquita Filho”(UNESP) School of Veterinary MedicineAraçatubaSao PauloBrazil Federal Rural University of Pernambuco(UFRPE) Department of Molecular SciencesRecifePernambucoBrazil Department of Biochemistry University of Nebraska-LincolnLincolnNE68508USA Federal University of Viçosa(UFV) Veterinary DepartmentViçosaMinas GeraisBrazil Federal University of Vale do São Francisco(UNIVASF) Department of Animal SciencePetrolinaPernambucoBrazil University of West Paulista(UNOESTE) Department of AgronomyPresidente PrudenteSao PauloBrazil Federal University of Goiás(UFG) Department of Veterinary MedicineGoiâniaGoiásBrazil

Antibiotic resistance represents a widespread problem in milk *** identification of compounds for a topically applied ointment used in mastitis therapy remains *** from the genus Hymenaea can be administered in cases of multi-drugresistant Staphylococcus aureus infection for ruminant species,but the protective properties are not well *** this research the aim is verify the protective effects of *** against *** infection in bovine mammary epithelial cell line(MAC-T)and to obtain an antioxidant profile evaluation in *** MAC-T cells were challenged with *** after being exposed to the extract of the *** in the protective *** the verification of the viability of the MAC-T cells,the MTT assay was performed,and was used dilutions of the plant extract,starting at 2.5%.The extract of *** was evaluated for antioxidant aspect in different dilutions by FRAP,ORAC and DPPH.A variety of flavonoids(quercetin,luteolin,etc.)have been identified as the main components by using mass spectrometry,reinforcing our in vitro findings that flavonoids,especially quercetin,have a medicinal profile capable of killing mastitis-causing *** excellent antioxidant pattern was observed in the 2.5%solution;however,membrane integrity in MAC-T cells was *** findings suggest low dilutions of *** extract has a desirable protective effect from *** *** in vitro studies can be gleaned upon for further in vivo studies.

关键词： Dairy animal Fitoterapic Hymenaea gender Cell activity Mastitis

MR导向下穿刺活检的临床路径:影响准确性及操作时间的因素

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国际医学放射学杂志 2012年第3期 295-295页

作者： R.Hoffmann C.Thomas H.Rempp D.Schmidt P.L.pereira C.D.claussen 李鹏 Department of Diagnostic and Interventional Radiology University of TübingenHoppe-Seyler-Strasse 372076 TübingenGermany

目的旨在评价MR导向下肝脏或软组织穿刺活检的准确性、持续时间及其相关影响因素。方法回顾性分析1.5TMR导向下19例肝脏活检及19例软组织活检的病例。评价其诊断效果和并发症。将介入操作时程分为准备期、穿刺期和控制期。分析操作时间... 详细信息

目的旨在评价MR导向下肝脏或软组织穿刺活检的准确性、持续时间及其相关影响因素。方法回顾性分析1.5TMR导向下19例肝脏活检及19例软组织活检的病例。评价其诊断效果和并发症。将介入操作时程分为准备期、穿刺期和控制期。分析操作时间与靶区大小、皮肤至靶区距离、

关键词：活检 MRI 磁共振成像,介入肝脏活检持续时间

肝脏肿瘤MR引导下微波消融术:常规临床应用的初步研究结果

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国际医学放射学杂志 2017年第3期 364-364页

作者： R.Hoffmann H.Rempp D.E.Keβler J.Weiβ P.L.pereira K.Nikolaou 郭小琴 Departments of Diagnostic and Interventional Radiology Eberhard-Karls-University

摘要目的评价对肝脏恶性肿瘤行MR引导下微波消融术的操作成功性、病人安全性以及技术有效性。方法经伦理委员会同意且获取病人的知情同意书。应用1.5 T MR系统对15例病人[(59.8±9.5)岁]的18个肝脏恶性肿瘤(7个肝细胞肝癌,11个转移瘤)... 详细信息

摘要目的评价对肝脏恶性肿瘤行MR引导下微波消融术的操作成功性、病人安全性以及技术有效性。方法经伦理委员会同意且获取病人的知情同意书。应用1.5 T MR系统对15例病人[(59.8±9.5)岁]的18个肝脏恶性肿瘤(7个肝细胞肝癌,11个转移瘤)行MR引导下微波消融术。平均肿瘤大小为(15.4±7.7)mm(7～37 mm)。操作成功性及消融区直径大小通过消融后MR成像进行测量评价。1个月后进行技术有效性的评价。根据常见不良事件评价标准(CTCAE)对并发症进行分类。平均随访时间为(5.8±2.6)个月(1～10个月)。

关键词： MR 微波消融术