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Hydroxychloroquine and a low antiresorptive activity bisphosphonate conjugate prevent and reverse ovariectomy-induced bone loss in mice through dual antiresorptive and anabolic effects
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Bone Research 2024年 第3期12卷 734-744页
作者: Zhenqiang Yao Akram Ayoub Venkatesan Srinivasan Jun Wu churou tang Rong Duan Aleksa Milosavljevic Lianping Xing Frank H.Ebetino Alison J.Frontier Brendan F.Boyce Department of Pathology and Laboratory Medicine University of Rochester Medical CenterRochesterNY 14642USA Department of Chemistry University of RochesterRochester NY14627USA School of Arts and Sciences University of RochesterRochester NY14627USA BioVinc LLCPasadenaCA 91107USA
Osteoporosis remains *** most widely used antiresorptive agents,bisphosphonates(BPs),also inhibit bone formation,while the anabolic agent,teriparatide,does not inhibit bone resorption,and thus they have limited effica... 详细信息
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