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未来食品学报(英文) 2023年第1期3卷 55-66页

作者： Xiaoyun Han Duo Yang song Zhang Xiaoli Liu Yuelong Zhao chunyue song Qingshen Sun Engineering Research Center of Agricultural Microbiology Technology Ministry of EducationHeilongjiang UniversityHarbin 150500China Key Laboratory of Molecular Biology College of Heilongjiang ProvinceSchool of Life SciencesHeilongjiang UniversityHarbin 150080China Key Laboratory of Microbiology College of Heilongjiang ProvinceSchool of Life SciencesHeilongjiang UniversityHarbin 150080China

The purpose of this study was to evaluate the obesity preventing or relieving effect of insoluble dietary fiber(IDF)from Pleurotus eryngii through its modulations on intestinal *** IDF was extracted and structurally characterized through FTIR,X-Ray and thermogravimetric(TG)*** mice for in vivo experiments were divided into obesity preventing group(feeding high-fat diet while gavage IDF simultaneously)and obesity relieving group(IDF intervention after the establishment of the obese model)to evaluate its hypolipidemic ***:The yield of *** IDF extracts was 56.49%(on *** dry weight base)with IDF content of 85.15%in the *** in vivo results showed that the body weight of the obesity-preventing groups was still increasing after intervention with IDF,but the growth rate was lowered,and the abnormal lipid metabolism and inflammation syndromes were alleviated;the acetic acid content of the medium and low dose dietary fiber intervention groups was significantly higher than that of the normal group,and the structure of the intestinal flora was *** mice weight from the obesity-relieving group decreased *** abnormal lipid metabolism and inflammation were *** conclusion,The IDF intervention decreased the abnormal lipid metabolism and inflammation in both obesity-preventing and relieving *** intestinal flora structure was obviously *** IDF is a good candidate as hypolipidemic agent.

关键词： Pleurotus eryngii Insoluble dietary fiber Obesity Intestinal microbiota Hypolipidemic effect

Modeling and Control of a Continuous Stirred Tank Reactor Based on a Mixed Logical Dynamical Model

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Chinese Journal of Chemical Engineering 2007年第4期15卷 533-538页

作者：杜静静宋春跃李平 State Key Lab of Industrial Control Technology Zhejiang University Hangzhou 310027 China

A novel control strategy for a continuous stirred tank reactor(CSTR)system,which has the typical characteristic of strongly pronounced nonlinearity,multiple operating points,and a wide operating range,is initiated from the point of hybrid *** proposed scheme makes full use of the modeling power of mixed logical dy- namical(MLD)systems to describe the highly nonlinear dynamics and multiple operating points in a unified framework as a hybrid system,and takes advantage of the good control quality of model predictive control(MPC) to design a ***,this approach avoids oscillation during switching between sub-systems,helps to relieve shaking in transition,and augments the stability robustness of the whole system,and finally achieves optimal(i.e. fast and smooth)transition between operating *** simulation results demonstrate that the presented ap- proach has a satisfactory performance.

关键词： continuous stirred tank reactor mixed logical dynamical model multiple-operating point state transition hybrid system

基于流向变换技术处理工业有机废气的控制系统设计

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化工进展 2006年第2期25卷 223-226页

作者：杨亮宋执环宋春跃浙江大学信息学院工业控制技术研究所杭州310027

综述了基于催化燃烧方法处理工业有机废气的控制系统的设计,指出该系统的控制对象为流向变换反应器,采用PLC控制系统完成控制功能。介绍了这种处理方法的理论依据,并提出控制系统的控制目标。以及对该处理过程的控制方法,以及控制系统... 详细信息

综述了基于催化燃烧方法处理工业有机废气的控制系统的设计,指出该系统的控制对象为流向变换反应器,采用PLC控制系统完成控制功能。介绍了这种处理方法的理论依据,并提出控制系统的控制目标。以及对该处理过程的控制方法,以及控制系统的硬件构成和程序设计。最后以实例说明该处理方法及其控制策略的有效性。

关键词：流向变换反应器有机废气控制系统可编程逻辑控制器(PLC)

Aurora B promotes the CENP-T–CENP-W interaction to guide accurate chromosome segregation in mitosis

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Journal of Molecular Cell Biology 2024年第2期16卷 11-23页

作者： Wei Liu Zhen Dou chunyue Wang Gangyin Zhao Fengge Wu Chunli Wang Felix Aikhionbare Mingliang Ye Divine Mensah Sedzro Zhenye Yang Chuanhai Fu Zhikai Wang Xinjiao Gao Xuebiao Yao Xiaoyu song Xing Liu MOE Key Laboratory for Cellular Dynamics Center for Advanced Interdisciplinary Science and Biomedicine of IHMUniversity of Science and Technology of China School of Life SciencesHefei 230027China Keck Center for Cellular Dynamics and Organoids Plasticity AtlantaGA 30310USA Anhui Key Laboratory for Cellular Dynamics and Chemical Biology Hefei National Research Center for Interdisciplinary Sciences at the MicroscaleHefei 230026China National Chromatographic Research and Analysis Center Chinese Academy of SciencesDalian 116023China

Accurate chromosome segregation in mitosis depends on kinetochores that connect centromeric chromatin to spindle *** are captured by individual microtubules via a kinetochore constitutive centromere-associated network(CCAN)during chromosome *** contains 16 subunits,including CENP-W and ***,the molecular recognition and mitotic regulation of the CCAN assembly remain ***,we revealed that CENP-W binds to the histone fold domain and an uncharacterized N-terminal region of *** B phosphorylates CENP-W at threonine 60,which enhances the interaction between CENP-W and CENP-T to ensure robust metaphase chromosome alignment and accurate chromosome segregation in *** findings delineate a conserved signaling cascade that integrates protein phosphorylation with CCAN integrity for the maintenance of genomic stability.

关键词： mitosis kinetochore Aurora B CENP-T CENP-W phosphorylation

Organization of microtubule plus-end dynamics by phase separation in mitosis

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Journal of Molecular Cell Biology 2024年第2期16卷 24-35页

作者： Fengrui Yang Mingrui Ding Xiaoyu song Fang Chen Tongtong Yang chunyue Wang Chengcheng Hu Qing Hu Yihan Yao Shihao Du Phil YYao Peng Xia Gregory Adams Jr Chuanhai Fu Shengqi Xiang Dan Liu Zhikai Wang Kai Yuan Xing Liu MOE Key Laboratory for Membraneless Organelles&Cellular Dynamics Hefei National Research Center for Cross-disciplinary SciencesCenter for Advanced Interdisciplinary Science and Biomedicine of IHMDivision of Life Sciences and MedicineUniversity of Science&Technology of ChinaHefei 230027China Anhui Key Laboratory for Cellular Dynamics and Chemical Biology University of Science&Technology of ChinaHefei 230027China Keck Center for Organoids Plasticity Morehouse School of MedicineAtlantaGA 30310USA Hunan Key Laboratory of Molecular Precision Medicine Central South UniversityChangsha 410083China

In eukaryotes,microtubule polymers are essential for cellular plasticity and fate ***-binding(EB)proteins serve as scaffolds for orchestrating microtubule polymer dynamics and are essential for cellular dynamics and chromosome segregation in ***,we show that EB1 forms molecular condensates with TIP150 and MCAK through liquid–liquid phase separation to compartmentalize the kinetochore–microtubule plus-end machinery,ensuring accurate kinetochore–microtubule interactions during chromosome segregation in *** of EB1–TIP150 polymer formation by a competing peptide prevents phase separation of the EB1-mediated complex and chromosome alignment at the metaphase equator in both cultured cells and Drosophila ***220 of EB1 is dynamically acetylated by p300/CBP-associated factor in early mitosis,and persistent acetylation at Lys220 attenuates phase separation of the EB1-mediated complex,dissolves droplets in vitro,and harnesses accurate chromosome *** data suggest a novel framework for understanding the organization and regulation of eukaryotic spindle for accurate chromosome segregation in mitosis.

关键词： phase separation mitosis microtubule dynamics EB1 acetylation

基于频响函数与主成分分析的网架结构损伤检测方法研究

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建筑结构 2017年第4期47卷 96-101页

作者：王孟鸿宋春月姬晨濛北京建筑大学土木与交通工程学院北京100044

为了研究网架结构杆单元的损伤检测方法,对网架结构在瞬时激励下的损伤检测进行了数值模拟分析和试验分析。为了判断网架结构的损伤杆件位置,选取合适的激励方式,设置了两种不同的工况进行分析,分别提取了结构在损伤前后的时域信号,运... 详细信息

为了研究网架结构杆单元的损伤检测方法,对网架结构在瞬时激励下的损伤检测进行了数值模拟分析和试验分析。为了判断网架结构的损伤杆件位置,选取合适的激励方式,设置了两种不同的工况进行分析,分别提取了结构在损伤前后的时域信号,运用频响函数和主成分分析进行数据处理,选取频响函数向量夹角作为结构损伤指标。数值模拟分析时,提取了结构全部节点的时域信号用来判断损伤杆单元的位置;试验分析时,在基于节点应变能系数的传感器优化布置方法的基础上,提取少量节点的时域信号,分两步逐渐缩小所要检测的损伤范围,最终确定损伤杆单元的位置。数值模拟分析和试验结果显示基于频响函数与主成分分析的损伤检测方法可以准确判断损伤的杆单元的位置。

关键词：损伤检测网架结构频响函数主成分分析

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种微控制器在CAN-USB转换中的设计

计算机测量与控制 2014年第9期22卷 2907-2909页

作者：王任重陈凌珊宋春月龙飞上海工程技术大学汽车工程学院上海201620 华东理工大学信息科学与工程学院上海200237

为了解决当前市场中昂贵的CAN—USB转换模块,提出了一种简单灵活且成本较低的基于Freescalel6位微控制器MC9S12XS128在CAN-USB转换模块中的设计方法,以解决CAN总线与PC主机的通讯问题;文章详细介绍了软硬件设计思路及流程,试验中设置CA... 详细信息

为了解决当前市场中昂贵的CAN—USB转换模块,提出了一种简单灵活且成本较低的基于Freescalel6位微控制器MC9S12XS128在CAN-USB转换模块中的设计方法,以解决CAN总线与PC主机的通讯问题;文章详细介绍了软硬件设计思路及流程,试验中设置CAN控制器为环路自检模式,串口波特率设置为9600,数据位设为8位,按照主程序设计流程,串口先接收8字节的0x88以确认串口的正确性,再接收8字节的CAN数据帧0x00~0x07;在测试期间CAN-USB模块累计运行10小时。试验证明该模块能完全满足CAN转USB的通讯需求,工作稳定可靠,简单易操作,实用性好。

关键词： MC9S12XS128 CAN-USB转换 SCI串口

Multi-PID Control of Hammerstein Systems with Input Multiplicity

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Multi-PID Control of Hammerstein Systems with Input Multipli...

中老年人群甘油三酯葡萄糖乘积指数与高血压的关联研究

第三十届中国控制会议

作者： DU Jingjing~1,ZHANG Xinliang~1,song chunyue~2 1.School of Electrical Engineering and Automation,Henan Polytechnic University,Jiaozuo 454000,P.R.China 2.State Key Lab.of Industrial Control Technology,Institute of Industrial Process Control, Zhejiang University,Hangzhou 310027,P.R.China

＜正＞Hammerstem models are popular in describing nonlinear chemical *** general control strategy for Hammerstem models is the nonlinearity inversion method,which is unfortunately inapplicable to Hammerstem systems with input *** overcome this difficulty,a Multi-PID control approach is ***,a complex control problem is solved by a conventional and

关键词： Hammerstein system Nonlinearity inversion method Input multiplicity Multi-PID

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中国动脉硬化杂志 2024年第7期32卷 583-589页

作者：赵建勇郭春月宋翠天津中医药大学第二附属医院重症医学科天津市300250 天津市第三中心医院研究中心天津市300170 天津市肿瘤医院空港医院心肺功能科天津市300308

[目的]探讨中国中老年人群中甘油三酯葡萄糖乘积(TyG)指数与高血压患病风险的相关性,为高血压的防治提供科学依据。[方法]数据来源于2011年中国健康与养老追踪调查(CHARLS)数据库,采用多阶段分层抽样方法选择研究对象。采用限制性立方... 详细信息

[目的]探讨中国中老年人群中甘油三酯葡萄糖乘积(TyG)指数与高血压患病风险的相关性,为高血压的防治提供科学依据。[方法]数据来源于2011年中国健康与养老追踪调查(CHARLS)数据库,采用多阶段分层抽样方法选择研究对象。采用限制性立方样条回归模型分析TyG指数与高血压风险的剂量-反应关系。采用多因素非条件Logistic回归模型评估TyG指数与高血压患病风险之间的关联。[结果]共9987例研究对象纳入分析,平均年龄为(59.16±9.43)岁,其中男性4707(47.13%)例。限制性立方样条回归模型结果显示,随着TyG指数的升高,高血压的患病风险增加,呈线性关联(总体关联检验P<0.0001,非线性关联检验P=0.2019)。多因素Logistic回归模型结果表明,与Q1(TyG指数<8.23)相比,Q2(8.23≤TyG指数<8.59)、Q3(8.59≤TyG指数<9.04)和Q4(TyG指数≥9.04)时,高血压的患病风险[OR(95%CI)]分别为1.09(0.95~1.26)、1.53(1.33~1.76)、1.77(1.52~2.06)。[结论]随着TyG指数的升高,高血压的患病风险逐渐增加。TyG指数可能是高血压患病的独立危险因素。

关键词：甘油三酯葡萄糖乘积指数高血压中老年人