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软坚散结方联合左甲状腺素钠治疗甲状腺癌术后患者疗效的Meta分析

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广州中医药大学学报 2024年第3期41卷 798-808页

作者：范浩群吴剑纯廖聪敖雪仁广州中医药大学广东广州510405 广州中医药大学第三附属医院广东广州510378

【目的】系统评价软坚散结方联合左甲状腺素钠治疗甲状腺癌术后的疗效,为临床治疗甲状腺癌术后提供循证依据。【方法】计算机检索国内外主要数据库中有关软坚散结方联合左甲状腺素钠治疗甲状腺癌术后的临床随机对照试验(randomized cont... 详细信息

【目的】系统评价软坚散结方联合左甲状腺素钠治疗甲状腺癌术后的疗效,为临床治疗甲状腺癌术后提供循证依据。【方法】计算机检索国内外主要数据库中有关软坚散结方联合左甲状腺素钠治疗甲状腺癌术后的临床随机对照试验(randomized controlled trials,RCTs)。根据文献纳入与排除标准筛选文献后,采用Cochrane系统评价员手册推荐的偏倚风险评估工具和改良JADAD评分量表进行纳入文献的质量评价,采用RevMan 5.4软件进行Meta分析。【结果】最终纳入11篇文献,涉及749例患者。Meta分析结果显示:与单纯左甲状腺素钠比较,软坚散结方联合左甲状腺素钠能显著提高甲状腺癌术后患者的疗效(RR=1.30,95%CI[1.21,1.41],Z=6.81,P<0.00001),改善甲状腺功能指标血清促甲状腺激素(TSH)(SMD=-1.75,95%CI[-2.38,-1.13],Z=5.47,P<0.00001)、甲状腺球蛋白(TG)(SMD=-1.13,95%CI[-1.71,-0.55],Z=3.81,P=0.0001)、游离三碘甲状腺原氨酸(FT3)(SMD=3.42,95%CI[0.73,6.10],Z=2.50,P=0.01)、游离甲状腺素(FT4)(SMD=1.85,95%CI[0.05,3.66],Z=2.02,P=0.04)、甲状腺球蛋白抗体(TgAb)(SMD=-0.63,95%CI[-1.11,-0.15],Z=2.55,P=0.01),改善Karnofsky功能状态(KPS)评分(SMD=2.19,95%CI[1.30,3.08],Z=4.81,P<0.00001),缩短甲状腺癌术后临床症状改善时间(MD=-4.67,95%CI[-5.38,-3.96],Z=12.87,P<0.00001),减小甲状腺癌术后最大甲状腺结节直径(MD=-2.51,95%CI[-3.13,-1.89],Z=7.94,P<0.00001),调节免疫功能指标T淋巴细胞群CD3+(MD=8.68,95%CI[4.97,12.39],Z=4.59,P<0.00001)、CD4+(MD=10.77,95%CI[5.46,16.08],Z=3.97,P<0.0001)水平,降低甲状腺癌术后并发症发生率(RR=0.34,95%CI[0.18,0.65],Z=3.26,P=0.001),差异均有统计学意义(P<0.05)。【结论】软坚散结方联合左甲状腺素钠能提高甲状腺癌术后患者的疗效,且其在改善甲状腺功能指标、KPS评分、临床症状改善时间、最大甲状腺结节直径、免疫功能指标、并发症发生率等方面优于单纯左甲状腺素钠。但因纳入本研究的文献数量较少,且因软坚散结法所用的方药也并未统一,本研究结论有待更多高质量、多中心、大样本的临床随机对照试验加以证实。

关键词：甲状腺癌术后软坚散结左甲状腺素钠疗效甲状腺功能 Meta分析

Preparation and characterization O-lauroyl chitosan/poly (L-lactic acid) blend membranes by solution-casting approach

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Chinese Chemical Letters 2007年第2期18卷 213-216页

作者： Yao Zu liao Mei Hua Xin Ming chun Li Sheng Su College of Materials Science and Engineering Huaqiao University Quanzhou 362021 China

O-Lauroyl chitosan/poly(l-lactide) (OCS/PLLA) blend membranes with different compositions were prepared by solution-casting approach using chloroform as common solvent. The experimental results of FT-IR, DSC and WAXD indicated that inter-association hydrogen-bond interactions existed between OCS and PLLA in the blend membranes. And SEM observation confirmed that the blend membranes with suitable compositions were compatible.

关键词： Hydrogen bond Chitosan PLLA Compatibility

Isolated cryptococcal osteomyelitis of the ulna in an immunocompetent patient:A case report

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World Journal of Clinical Cases 2022年第19期10卷 6617-6625页

作者： Jing-Long Ma Liang liao Tao Wan Fu-chun Yang Department of Orthopedic Trauma and Hand Surgery The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi ProvinceChina Guangxi Key Laboratory of Regenerative Medicine Department of OrthopedicsThe First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi ProvinceChina

BACKGROUND Cryptococcal osteomyelitis is a bone infection caused by *** an opportunistic infection,bone cryptococcosis usually occurs in patients with immunodeficiency diseases or in those undergoing immunosuppressive therapy and often displays characteristics of disseminated *** cryptococcal osteomyelitis is extremely unusual in immunocompetent *** pathogenic fungus often invades vertebrae,femur,tibia,rib,clavicle,pelvis,and humerus,but the ulna is a rare *** SUMMARY A 79-year-old woman complaining of chronic pain,skin ulceration and a sinus on her right forearm was admitted,and soon after was diagnosed with cryptococcal osteomyelitis in the right ***,she was also found to have apparently normal *** treatment with antifungal therapy combined with surgery debridement,the patient’s osteomyelitis healed with a satisfactory *** Although rare,cryptococcal osteomyelitis should be considered in the differential diagnosis of osteolytic lesions even in immunocompetent patients,and good outcomes can be expected if early definitive diagnosis and etiological treatment are established.

关键词： Cryptococcus neoformans Osteomyelitis Isolated lesions Ulna Immunocompetence Case report

Minimum Amount of Extracting Solvent of (A_(1)A_(2)…A_(t−1))/(A_(2)A_(3)…A_(t)) Separation When Using Non-barren Extracting Solvent

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Chinese Journal of Chemistry 2014年第10期32卷 1022-1028页

作者： Fu-Xiang Cheng Sheng Wu Song-Ling Wang Bo Zhang Yan Liu chun-Sheng liao chun-Hua Yan Beijing National Laboratory for Molecular Sciences State Key Laboratory of Rare Earth Materials Chemistry and ApplicationsPKU-HKU Joint Lab on Rare Earth Materials and Bioinorganic ChemistryPeking UniversityBeijing 100871China China Minmetals(Beijing)Research Institute of RE Co. LtdBeijing 100085China

Hyperlink extraction technology,by virtue of its remarkable advantage of decreasing the use of chemicals in multi-component separation,has been extensively employed in rare earth separation industry in *** hyperlink processes,non-barren extracting solvent and scrubbing agent solution which contain the component(s)involved in starting feed are employed in order to save both alkali for saponification and acid for *** amount of extracting solvent(denoted as S_(min))and that of scrubbing agent solution(denoted as W_(min))are important parameters to determine the consumption amounts of alkali and acid for a given countercurrent extraction *** article therefore discusses the influence of using non-barren extracting solvent and scrubbing agent solution on S_(min) and W_(min) of an(A_(1)A_(2)…A_(t−1))/(A_(2)A_(3)…A_(t))*** equations for S_(min) and W_(min) are derived,and the variation of the composition of final raffinate as well as that of final extract are determined,which will provide a valuable guidance for the design of hyperlink extraction processes of multi-component separation,such as rare earths separation.

关键词： minimum amount of extracting solvent rare earths hyperlink process multi-component separation

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两相出口对轴向涡流分离器的影响研究

石油机械 2024年第5期52卷 116-123页

作者：娄焕伟张兴凯刘旭煜王智慧廖锐全叶春长江大学中石油气举试验基地多相流实验室长江大学油气钻采工程湖北省重点实验室

为了更好地预测分离器的分离效率和设计出更高效的分离器,应进一步了解其内部流场分布特性及不同结构参数对内部流场的影响。为此,采用Fluent软件对轴向涡流分离器内部流场分布特性和分离器两相出口结构对内部流场及分离性能的影响展开... 详细信息

为了更好地预测分离器的分离效率和设计出更高效的分离器,应进一步了解其内部流场分布特性及不同结构参数对内部流场的影响。为此,采用Fluent软件对轴向涡流分离器内部流场分布特性和分离器两相出口结构对内部流场及分离性能的影响展开研究。研究结果表明:当水相出口直径增加到40 mm时,轴向涡流分离器水相出口处会形成一个低速回流区域,可通过减小管径收缩程度等方法来缓解该现象的影响;在其他结构参数不变的情况下,分离器的分离效率是关于雷诺数和两相出口与入口直径之比的函数;分离效率正比于油相出口与入口直径之比,与雷诺数、水相出口与入口直径之比均为二次函数关系。研究结论可为进一步优化轴向涡流分离器的分离性能提供理论参考。

关键词：轴向涡流分离器分离性能数值模拟流场分析影响因素

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Mo_(2)C添加量对YG6细晶硬质合金组织结构及性能的影响

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稀有金属与硬质合金 2024年第2期52卷 70-75页

作者：董凯林廖军时凯华刁椿珉张钱伟江佳阳自贡硬质合金有限责任公司四川自贡643011

采用传统粉末冶金方法制备了不同Mo_(2)C添加量的YG6细晶硬质合金。通过对合金显微结构的观察及物理力学性能的检测,研究了Mo_(2)C添加量对YG6细晶硬质合金组织结构及性能的影响。结果表明:随着Mo_(2)C添加量的增加,合金中WC晶粒度逐渐... 详细信息

采用传统粉末冶金方法制备了不同Mo_(2)C添加量的YG6细晶硬质合金。通过对合金显微结构的观察及物理力学性能的检测,研究了Mo_(2)C添加量对YG6细晶硬质合金组织结构及性能的影响。结果表明:随着Mo_(2)C添加量的增加,合金中WC晶粒度逐渐细化并趋于稳定。当合金中Mo_(2)C添加量超过3.5%时,Mo_(2)C对WC晶粒形貌具有球化作用。另外,添加Mo_(2)C会降低合金致密度,合金矫顽磁力随Mo_(2)C含量的增加而逐渐增加。Mo_(2)C添加量为5.0%时,合金综合力学性能最好,其硬度达92.7 HRA,抗弯强度为3 600 MPa,磨粒磨损值为0.81 cm^(3)/(10^(5)r)。

关键词：硬质合金 Mo_(2)C 组织结构性能

太阳能吸收压缩制冷与真空膜除湿耦合系统性能优化

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制冷与空调（四川） 2024年第3期38卷 305-312页

作者：袁伦睿淳良刘东廖子成西南科技大学土木工程与建筑学院绵阳621010

对于太阳能吸收式制冷系统,很难产生较低温的冷冻水用于除湿和冷却,并且面临间歇性的问题。提出了一种新型的温湿度独立控制系统(SACV),该系统集成了太阳能吸收式制冷(SSAR)子系统、蒸汽压缩制冷(VCR)子系统和真空膜除湿(VMD)子系统。VM... 详细信息

对于太阳能吸收式制冷系统,很难产生较低温的冷冻水用于除湿和冷却,并且面临间歇性的问题。提出了一种新型的温湿度独立控制系统(SACV),该系统集成了太阳能吸收式制冷(SSAR)子系统、蒸汽压缩制冷(VCR)子系统和真空膜除湿(VMD)子系统。VMD子系统和VCR子系统分别解决了除湿困难和全天候制冷问题。建立并验证了热力学数学模型,分析了集热器面积和热水流量对集热器出口热水温度的影响,以及对集热器、SSAR子系统和SACV系统性能的影响,并对SSAR子系统和SACV系统进行了性能优化。结果表明,集热器出口热水温度的增加,使得SSAR子系统存在最佳性能;通过变化热水流量来改变集热器出口热水温度,使得SACV系统存在最佳性能。集热器面积增加73.7%,SSAR子系统性能到达最佳,提升了0.24%,制冷量增长69.64%,同时SACV系统性能提升4.71%,耗功量减少36.18%,但系统成本增加,因此,需要综合考虑系统性能和经济效益。

关键词：太阳能吸收式制冷膜除湿集热器出口热水温度优化

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强力网堵漏技术及施工工艺分析

石化技术 2024年第5期31卷 144-146页

作者：廖龙刘坤翔鲁毅杨纯陈香琴中海石油(中国)有限公司深圳分公司广东深圳518067

南海海域新近系珠江组地层广泛发育灰岩裂缝,连通性好,易漏失。分别是陆丰、惠州两个区块,井漏事故,主要集中在新近系珠江组灰岩、砂岩及灰质粉砂岩层段,漏失现象存在于正常钻进、处理井下事故、起钻及测压作业等过程中。灰岩地层漏失... 详细信息

南海海域新近系珠江组地层广泛发育灰岩裂缝,连通性好,易漏失。分别是陆丰、惠州两个区块,井漏事故,主要集中在新近系珠江组灰岩、砂岩及灰质粉砂岩层段,漏失现象存在于正常钻进、处理井下事故、起钻及测压作业等过程中。灰岩地层漏失具有速度快、常规堵漏手段见效慢、损失时间长的特点,因此,针对这种漏失情况,分析了漏失机理,针对珠江组灰岩地层微孔隙及微裂缝扩展导致的裂缝扩展性漏失,剔除了一种强力网堵漏材料NETLOCK,实验室性能表明其具可以显著提高堵漏成功率,具有很高的推广意义。

关键词：灰岩裂缝漏失机理防漏堵漏强力网堵漏

Fabrication and characterization of mussel-inspired layer-by-layer assembled CL-20-based energetic films via micro-jet printing

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Defence Technology（防务技术） 2022年第10期18卷 1748-1759页

作者： chun-yan Li Sheng Kong Dong-jie liao Chong-wei An Bao-yun Ye Jing-yu Wang School of Environment and Safety Engineering North University of ChinaTaiyuan030051ShanxiChina Shanxi Engineering Technology Research Center for Ultrafine Powder North University of ChinaTaiyuan030051ShanxiChina Taiyuan Institute of Technology Taiyuan030008ShanxiChina

Three-dimensional(3D)micro-jet printing is a droplet deposition technique based on liquid-phase *** improve the deposition density and performance of energetic films with micro/nanoscale on an energetic chip,polydopamine(PDA)was utilized as a linker bridge to induce the in-situ self-assembly of CL-20-based energetic film via 3D micro-jet *** self-assembly was extensively characterized by confocal laser scanning microscopy(CLSM),SEM,power-XRD,XPS,and *** performance of the self-assembled film was verified by the mechanical properties and detonation properties,and a possible self-assembly mechanism in the layer-by-layer micro-jet printing process was *** results indicated PDA-induced self-assembly enhanced the physical entanglement between the binders and energetic crystal,reduced the porosity from 15.87%to 11.28%,and improved the elastic modulus and the detonation performance of the CL-20-based energetic *** work proposes a novel and promising energetic film design and fabrication strategy to enhance the interaction between the energetic composite layers in the micro-jet printing process.

关键词： CL-20-Based energetic film Micro-jet printing Polydopamine Self-assembly