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Ore Geology,H-O-C Isotopes and 40Ar-39Ar Dating of the Wutonggou Iron Deposit,Eastern Tianshan,NW China:Implications for the Source,Timing,and Genesis of Hydrothermal Mineralization in a Sedimentary Iron Deposit

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Journal of Earth Science 2024年第4期35卷 1170-1185页

作者： chun.Long Wang Yi-Tian Wang State Key Laboratory of Geological Processes and Mineral Resources Collaborative Innovation Center for Exploration of Strategic Mineral ResourcesSchool of Earth ResourcesChina University of GeosciencesWuhan430074China MNR Key Laboratory of Metallogeny and Mineral Assessment Institute of Mineral ResourcesChinese Academy of Geological SciencesBeijing100037China

The Wutonggou iron deposit is located in the well-known iron metallogenic belt in the eastern Tianshan,NW China,and has been regarded as a sedimentary iron *** hydrothermal overprinting could play indispensable roles in the formation of high-grade iron ores in sedimentary iron deposits,previous studies mainly focused on sedimentary-related iron mineralization,while the nature and contribution of hydrothermal fluids are poorly ***,an integrated study of ore geology,H-O-C isotopes and^(40)Ar-^(39)Ar dating,is conducted on the Wutonggou deposit,in order to reveal the features,source,and timing of hydrothermal *** studied deposit includes two mining sections namely the Jianshan and ***δ^(18)O values of early magnetite from the Jianshan section range from+3.0‰to+5.8‰that nearly consistent with classic magmatic magnetite,while increase to 6.3‰-8.0‰in the late *** from the two sections shows comparable H-O isotopic compositions and identical fractionation trends,and is plotted in or periphery to the primary magmatic water *** from the two sections are broadly similar in carbon and oxygen isotopic compositions,and siderite from the Wutonggou section is plotted in the same ***,comparable stable isotopic compositions and evolution trends indicate similar magmatic fluids contributed hydrothermal iron mineralization in the two mining ***,water-rock interactions of varying degrees generated distinct mineralization styles in the Jianshan and Wutonggou sections,and caused the isotopic fractionation in late *** extracted from a hydrothermal siderite ore yielded a^(40)Ar-^(39)Ar plateau age of 299.5±2.0 Ma,indicates the timing of hydrothermal iron mineralization is corresponding to the emplacement of vicinity *** together,the hydrothermal mineralization in the Wutonggou iron deposit was the product of remobilization and upgrading of early sedimentary iron ores,a

关键词： iron deposits H-O-C isotopes 40Ar-39Ar dating sedimentary iron deposits Wutonggou iron deposit eastern Tianshan

Navigating the safe operation of high-voltage cathodes:Challenges and strategies

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Nano Research 2024年第10期17卷 8694-8705页

作者： Yue Sun Changjian Zuo Yi-chun.Lu Electrochemical Energy and Interfaces Laboratory Department of Mechanical and Automation EngineeringThe Chinese University of Hong KongHong Kong 999077China

Lithium-ion batteries play a crucial role in storing energy for renewable sources and electric vehicles,yet face challenges related to insufficient energy *** the working-voltage of cathodes is promising to boost the energy density of batteries by increasing both the output voltage and capacity of cathode,which however could compromise life cycle and *** review provides a comprehensive summary of essential factors governing pathways of cathode-induced thermal runaway,including electrolyte decomposition,phase transitions,and crosstalk-induced *** and electrolyte modifications aimed at mitigating parasitic reactions and preventing crosstalk were also *** review concludes with insights into the future application of these strategies,providing a comprehensive perspective on the realization of high-energy and safe batteries.

关键词： battery safety high-voltage cathode lithium-ion battery thermal runaway

Proteomics Study of Benzene Metabolite Hydroquinone Induced Hematotoxicity in K562 Cells

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Biomedical and Environmental Sciences 2024年第4期37卷 341-353页

作者： JIN Yi Shan YI Zong chun.ZHANG Yu Jing RONG Long YU chun.Hong School of Biological Science and Medical Engineering Beihang UniversityBeijing 100191China School of Engineering Medicine Beihang UniversityBeijing 100191China

Objective Hydroquinone(HQ),one of the phenolic metabolites of benzene,is widely recognized as an important participant in benzene-induced ***,there are few relevant proteomics in HQ-induced hematotoxicity and the mechanism hasn’t been fully understood *** In this study,we treated K562 cells with 40μmol/L HQ for 72 h,examined and validated protein expression changes by Label-free proteomic analysis and Parallel reaction monitoring(PRM),and performed bioinformatics analysis to identify interaction *** One hundred and eighty-seven upregulated differentially expressed proteins(DEPs)and 279 downregulated DEPs were identified in HQ-exposed K562 cells,which were involved in neutrophilmediated immunity,blood microparticle,and other GO terms,as well as the lysosome,metabolic,cell cycle,and cellular senescence-related *** on the 23 DEGs and 5 DEPs in erythroid differentiation-related pathways,we constructed the network of protein interactions and determined 6 DEPs(STAT1,STAT3,CASP3,KIT,STAT5B,and VEGFA)as main hub proteins with the most interactions,among which STAts made a central impact and may be potential biomarkers of HQ-induced *** Our work reinforced the use of proteomics and bioinformatic approaches to advance knowledge on molecular mechanisms of HQ-induced hematotoxicity at the protein level and provide a valuable basis for further clarification.

关键词： Hydroquinone Proteomics Hematotoxicity K562 cells

In-situ powder mixing for laser-based directed energy deposition of functionally graded materials

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Advances in Manufacturing 2024年第1期12卷 150-166页

作者： Ji-Peng Chen Shou-chun.Xie He Huang School of Mechanical and Electronic Engineering Nanjing Forestry UniversityNanjing210037People’s Republic of China Nanjing Huirui Photoelectric Technology Co. LtdNanjing211121People’s Republic of China

The mixing of powders is a highly relevant field under additive manufacturing,however,it has attracted limited interest to *** in-situ mixing of various powders remains a significant *** paper proposes a new method utilizing a static mixer for the in-situ mixing of multiple powders through the laser-based directed energy deposition(DED)of functionally graded ***,a powder-mixing experimental platform was established;WC and 316L powders were selected for the mixing ***,scanning electron microscopy,energy dispersive spectroscopy,and image processing were used to visually evaluate the homogeneity and proportion of the in-situ mixed ***,powder-mixing simulations were conducted to determine the powder-mixing *** the simulations,a powder carrier gas flow field and particle mixing were ***,a WC/316L metal matrix composite sample was produced using laser-based DED to verify the application potential of the static *** was found that the static mixer could adjust the powder ratio online,and a response time of 1–2 s should be considered when adjusting the ratio of the mixed powder.A feasible approach for in-situ powder mixing for laser-based DED was demonstrated and investigated,creating the basis for functionally graded materials.

关键词： Laser Deposition Static mixer Powder mixing Functionally graded materials

Regulating depletion region enables highly efficient and stable perovskite solar cells

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Science China Chemistry 2024年第9期67卷 2783-2784页

作者： chun.Yun Wang Michael Saliba Institute for Photovoltaics(ipv) University of Stuttgart70569 StuttgartGermany IEK5-Photovoltaics Forschungszentrum Jülich52425 JülichGermany

Perovskite solar cells(PSCs)have made impressive strides in recent years with the power conversion efficiency(PCE)now exceeding 26%[1],which is comparable to established technologies such as ***,the ion migration in perovskites causes undesirable hysteresis and *** affects the long-term operational stability of PSCs,hampering a possible industrialization.

关键词： perovskite depletion exceeding

Ellagic acid inhibits gastric cancer cells by modulating oxidative stress and inducing apoptosis

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Asian Pacific Journal of Tropical Biomedicine 2024年第4期14卷 162-169页

作者： Jian Zheng chun.Feng Li Department of Diagnostic Radiology Division Harbin Medical University Cancer HospitalHeilongjiangChina Department of Gastrointestinal Surgical Ward Harbin Medical University Cancer HospitalHeilongjiangChina

Objective:To evaluate the anticancer effect of ellagic acid on gastric cancer ***:MTT assay was used to evaluate the effect of ellagic acid at different concentrations(0.5-100μg/mL)on gastric cancer AGS ***-qPCR and Western blot analyses were applied to assess apoptosis(BCL-2,CASP-3,and BAX)and autophagy(LC3,ATG5,and BECN1)in AGS cells treated with ellagic *** expression of invasion-related markers including TP53,CDKN2A,and PTEN was *** addition,cell cycle markers including cyclin A,B,D,and E were measured by *** stress markers were evaluated using ***:Ellagic acid inhibited the proliferation of AGS cells in a concentration-and time-dependent *** expression of BCL-2 was significantly decreased(P0.05).Moreover,the oxidative stress markers including SOD,TAC,and MDA were increased by ellagic acid(Pts anticancer efficacy.

关键词： Ellagic acid Gastric cancer Apoptosis Autophagy Metastasis Proliferation

MAP4K inhibition as a potential therapy for amyotrophic lateral sclerosis

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Neural Regeneration Research 2024年第8期19卷 1639-1640页

作者： Shuaipeng Ma chun.Li Zhang Department of Molecular Biology University of Texas Southwestern Medical CenterDallasTXUSA Hamon Center for Regenerative Science and Medicine University of Texas Southwestern Medical CenterDallasTXUSA

Amyotrophic lateral sclerosis(ALS)is a rare neurological disease,featuring gradual loss of muscle controls due to degeneration of motor ***,there is currently no cure for *** available therapies only offer a limited e... 详细信息

关键词： degeneration sclerosis MAP4

Context Processing in Contextual and Cued Fear Extinction

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Neuroscience Bulletin 2024年第6期40卷 835-839页

作者： Yimu Zhang chun.Xu Yu Gu State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science Institutes of Brain ScienceFudan UniversityShanghai200032China Institute of Neuroscience State Key Laboratory of NeuroscienceCenter for Excellence in Brain Science and Intelligence TechnologyChinese Academy of SciencesShanghai200031China

Anxiety disorders such as post-traumatic stress disorder(PtsD)are prevalent mental disorders that disturb millions *** disorders often manifest as excessive fear,anxiety,and distress,significantly impacting daily *** fear extinction paradigms in animals were established decades ago and have been widely used in research,providing a scientific basis for exposure therapies for anxiety disorders in humans.

关键词： distress disorders traumatic

Evolution of Diagenetic Fluid of the Dawsonite-Bearing Sandstone in the Jiyang Depression,Eastern China

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Journal of Ocean University of China 2024年第1期23卷 80-98页

作者： LI Fulai MA Wenkuan ZHANG chun.WANG Kaining National Key Laboratory of Deep Oil and Gas China University of Petroleum(East China)Qingdao 266580China Laboratory for Marine Mineral Resources Qingdao National Laboratory for Marine Science and TechnologyQingdao 266071China Shandong Geological Exploration Institute of China Chemical Geology and Mine Bureau Jinan 250013China

Based on the petrology,isotope geochemistry and fluid inclusions analysis,we established the evolutionary mode of the diagenetic fluid of dawsonite-bearing sandstone in the Jiyang ***-bearing sandstone is characterized by double injection of CO_(2)and oil-gas in the Jiyang Depression that have experienced a relatively complex diagenetic fluid evolution *** diagenetic sequence of secondary minerals involves secondary enlargement of quartz,kaolinite,first-stage calcite,dawsonite,second-stage calcite,ferrocalcite,dolomite and *** charging in the dawsonite-bearing sandstone occurred at around 2.6–0 *** CO_(2)charging event occurred during Dongying tectonism,forming the Pingfangwang CO_(2)gas reservoir,which provided an abundant carbon source for dawsonite *** and oxygen isotopic compositions of dawsonite demonstrate that CO_(2)forming the dawsonite was of an inorganic origin derived from the mantle,and that water mediating the proc-ess during dawsonite precipitation was sequestered brine with a fluid temperature of 82℃.The evolutionary sequence of the diagenetic fluid in the dawsonite-bearing sandstone was:alkaline syngenetic fluids,weak alkaline fluids during organic acid forma-tion,acidic fluids in the early stage of CO_(2)injection,alkaline fluids in the late stage of CO_(2)injection,and weak alkaline fluids during oil and gas *** mode indicates an increase in-HCO_(3)because of the CO_(2)injection,and the loss of Ca^(2+)and Mg^(2+)due to the precipitation of carbonate ***,the evolutionary mode of diagenetic fluids is in good agreement with high HCO_(3)^(-),low Ca^(2+)and low Mg^(2+)composition of the present formation water in the dawsonite-bearing sandstone.

关键词： evolution of diagenetic fluid dawsonite CO_(2)injection and hydrocarbon charging mineral diagenetic sequence iso-topic geochemistry fluid inclusions