检索结果-南通市图书馆

Resveratrol as a novel agent for treatment of multiple myeloma with matrix metalloproteinase inhibitory activity

Acta Pharmacologica Sinica 2006年第11期27卷 1447-1452页

作者： chun-yan sun~1 yu hu~(1,3)tao guo~1 hua-fang wang~1 xiao-ping zhang~1 wen-juan he~1 hao tan~2 1 institute of hematology,union hospital,tongji medical college,huazhong university of science and technology.wuhan 430022 2 institute of Occupational Medicine,School of Public health,tongji medical college,huazhong Universtiy of science and technology.wuhan 430030,China institute of hematology Union Hospital Tongji medical college Huazhong University of Science and Technology Wuhan China institute of Occupational Medicine School of Public Health Tongji Medical College Huazhong Universtiy of Science and Technology Wuhan China

Aim:To examine the in vitro antitumor activity of resveratrol against multiplemyeloma（MM）cell lines（RPMI 8226,U266,and KM3）,and the ***:The growth inhibition of resveratrol was determined by 3-（4,5-dimethyl-2-thiazyl）-2,5-diphenyl-2H-tetrazolium bromide（MTT）*** of resveratrol on the apoptosis was investigated by combined annexin V-propidium iodide *** effect of resveratrol on the invasion throughMatrigel matrix was detected by transwell invasion *** activity ofmatrix metalloproteinase（MMP）-2 and -9 proteins were determined by gelatinzymography *** expression of MMP-2,MMP-9,Bcl-2,Bcl-xL,XIAPand Bax protein were detected using Western blotting ***:Resveratrol inhibited proliferation of MM cells in a dose-and *** of MM cells with resveratrol resulted in apoptotic cell *** down-regulated the expression of the antiapoptotic proteins Bcl-2,Bcl-xLand XIAP and up-regulated the expression of the proapoptotic protein ***,resveratrol inhibited invasion of RPMI 8226,U266,and KM3 cellswith IC50values of 64±8 μmol/L,93±11 μmol/L,and 153±11 μmol/L,*** inhibited the constitutive expression of MMP-2 and-9 proteins ofMM cells and suppressed its gelatinolytic ***:Resveratrol in-hibits the proliferation of MM cells by inducing apoptotic cell *** inhibits MM cell *** inhibition of invasion may be associated withthe attenuation of the enzymatic activities of MMP-2 and-9.

关键词： resveratrol multiple myeloma proliferation invasion matrix metalloproteinase

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Effect and Safety of herbal Medicine Foot Baths in Patients with Diabetic Peripheral Neuropathy:A Multicenter Double-Blind Randomized Controlled Trial

引用

Chinese Journal of Integrative Medicine 2024年第3期30卷 195-202页

作者： huaNG hao-yue LIN yu-ping WEI hua FU yu ZHOU yue-hong fang Zhao-hui QIU xiao-tang wang Mei LI Qing-bo LI Shan-shan wang Shi-dong DAI fang LIU Zhen-jie Zhao Ling wen Jian-xuan WU Li-yan ZENG hui-yan zhang Jin-ming LU Qi-yun he Liu SONG Wei sun Lu LUO Lu-lu he Jia-li XIE wen-wen LIANG Qing-shun huaNG yuan Zhu Sheng-ling LONG Jie-er GAO Zhi-juan wen Ze-huai LI chun-ji OUyanG wen-wei LI Geng WU Ming-hui LI An-xiang huaNG Jin-zhu Sanjoy K Paul tanG Xian-yu FAN Guan-jie Department of Endocrinology Guangdong Provincial Hospital of Chinese MedicineGuangzhou510120China The Second Clinical college of Guangzhou university of Chinese Medicine Guangzhou510120China Department of Endocrinology The Second Affiliated Hospital of Guangzhou University of Chinese MedicineGuangzhou510120China Guangdong Provincial Academy of Chinese medical sciences Guangzhou510120China Department of Endocrinology The First Affiliated Hospital of Henan University of Chinese MedicineZhengzhou450000China Department of Endocrinology Liuyang Hospital of Chinese MedicineChangsha410000China Department of Endocrinology The First Affiliated Hospital of Anhui University of Chinese MedicineHefei230000China Department of Endocrinology Hainan Provincial Hospital of Traditional Chinese MedicineHaikou570100China Department of Endocrinology The Affiliated Hospital of Liaoning University of Traditional Chinese MedicineShenyang110000China Department of Geriatric Luoyang No.1 Hospital of Traditional Chinese MedicineLuoyangHenan Province471000China Department of Endocrinology The Second Affiliated Hospital of Guizhou University of Traditional Chinese MedicineGuiyang550000China Department of Endocrinology Beijing University of Chinese Medicine Affiliated Dongzhimen HospitalBeijing100000China Department of Endocrinology The First Affiliated Hospital of Guizhou University of Traditional Chinese MedicineGuiyang550000China Melbourne EpiCentre The University of Melbourne and Melbourne HealthMelbourne3013Australia

Objective:To evaluate the effect and safety of foot baths with tangbi Waixi Decoction(TW)in treating patients with diabetic peripheral neuropathy(DPN).Methods:It is a multicenter double-blinded randomized controlled *** with DPN were recruited between November 18,2016 and May 30,2018 from 8 hospitals in *** patients received basic treatments for glycemic *** received foot baths with TW herbal granules either 66.9 g(intervention group)or 6.69 g(control group)for 30 min once a day for 2 weeks and followed by a 2-week rest,as a therapeutic *** the Toronto Clinical Scoring System total score(TCSS-TS)6 points,the patients received a total of 3 therapeutic courses(for 12 weeks)and were followed up for 12 *** primary outcome was change in TCSS-TS score at 12 and 24 *** outcomes included changes in bilateral motor nerve conduction velocity(MNCV)and sensory nerve conduction velocity(SNCV)of the median and common peroneal *** was also ***:Totally 632 patients were enrolled,and 317 and 315 were randomized to the intervention and control groups,*** the 12-week intervention,patients in both groups showed significant declines in TCSSTS scores,and significant increases in MNCV and SNCV of the median and common peroneal nerves compared with pre-treatment(Phe reduction of TCSS-TS score at 12 weeks and the increase of SNCV of median nerve at 24 weeks in the control group were greater than those in the intervention group(Phe number of adverse events did not differ significantly between groups(P>0.05),and no serious adverse event was related with ***:Treatment of TW foot baths was safe and significantly benefitted patients with DPN.A low dose of TW appeared to be more effective than a high dose.(Registry *** CTR-IOR-16009331)

关键词： diabetic peripheral neuropathy herbal medicine foot baths Chinese medicine randomized controlled trial tangbi Waixi Decoction

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The Chinese Society of Clinical Oncology (CSCO): Clinical guidelines for the diagnosis and treatment of gastric cancer, 2023

引用

Cancer Communications 2024年第1期44卷 127-172页

作者： Feng-hua wang xiao-Tian zhang Lei tang Qi Wu Mu-yan Cai yuan-fang Li Xiu-juan Qu Hong Qiu yu-Jing zhang Jie-Er Ying Jun zhang Ling-yu sun Rong-Bo Lin Chang wang hao Liu Miao-Zhen Qiu wen-Long Guan Sheng-Xiang Rao Jia-Fu Ji yan Xin Wei-Qi Sheng hui-Mian Xu Zhi-Wei Zhou Ai-ping Zhou Jing Jin Xiang-Lin yuan Feng Bi Tian-Shu Liu Han Liang yan-Qiao zhang guo-Xin Li Jun Liang Bao-Rui Liu Lin Shen Jin Li Rui-hua Xu Department of medical Oncology Sun Yat-sen University Cancer CenterState Key Laboratory of Oncology in South ChinaCollaborative Innovation Center for Cancer MedicineGuangzhouGuangdongP.R.China Department of Gastrointestinal Oncology Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education)Peking University Cancer HospitalBeijingP.R.China Department of Radiology Peking University Cancer HospitalBeijingP.R.China Department of Endoscopy Center Peking University Cancer HospitalBeijingP.R.China Department of Pathology Sun Yat-sen University Cancer CenterState Key Laboratory of Oncology in South ChinaCollaborative Innovation Center of Cancer MedicineGuangzhouGuangdongP.R.China Department of Gastric Surgery Sun Yat-sen University Cancer CenterState Key Laboratory of Oncology in South ChinaCollaborative Innovation Center for Cancer MedicineGuangzhouGuangdongP.R.China Department of medical Oncology The First Hospital of China Medical UniversityShenyangLiaoningP.R.China Department of medical Oncology Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and TechnologyWuhanHubeiP.R.China Department of Radiotherapy Sun Yat-sen University Cancer CenterState Key Laboratory of Oncology in South ChinaCollaborative Innovation Center for Cancer MedicineGuangzhouGuangdongP.R.China Department of medical Oncology Zhejiang Cancer HospitalHangzhouZhejiangP.R.China Department of medical Oncology Ruijin HospitalShanghai Jiaotong University School of MedicineShanghaiP.R.China Department of Surgical Oncology The Fourth Affiliated Hospital of Harbin Medical UniversityHarbinHeilongjiangP.R.China Department of medical Oncology Fujian Cancer HospitalFuzhouFujianP.R.China Tumor Center The First Hospital of Jilin UniversityChangchunJilinP.R.China Department of General Surgery Nanfang HospitalSouthern Medical UniversityGuangzhouGuangdongP.R.China Department of Radiology Zhongshan HospitalFudan UniversityShanghaiP.R.China Department of

The 2023 update of the Chinese Society of Clinical Oncology(CSCO)Clini-cal Guidelines for Gastric Cancer focuses on standardizing cancer diagnosis and treatment in China,reflecting the latest advancements in evidence-based medicine,healthcare resource availability,and precision *** updates address the differences in epidemiological characteristics,clinicopatho-logical features,tumor biology,treatment patterns,and drug selections between Eastern and Western gastric cancer *** revisions include a structured template for imaging diagnosis reports,updated standards for molecular marker testing in pathological diagnosis,and an elevated recommendation for neoadju-vant chemotherapy in stage III gastric *** advanced metastatic gastric cancer,the guidelines introduce new recommendations for immunotherapy,anti-angiogenic therapy and targeted drugs,along with updated management strategies for human epidermal growth factor receptor 2(heR2)-positive and deficient DNA mismatch repair(dMMR)/microsatellite instability-high(MSI-H)***,the guidelines offer detailed screening recommendations for hereditary gastric cancer and an appendix listing drug treatment regimens for various stages of gastric *** 2023 CSCO Clinical Guidelines for Gastric Cancer updates are based on both Chinese and international clinical research and expert consensus to enhance their applicability and relevance in clinical practice,particularly in the heterogeneous healthcare landscape of China,while maintaining a commitment to scientific rigor,impartiality,and timely revisions.

关键词： Chinese Society of Clinical Oncology(CSCO) gastric cancer diagnosis surgery neoadjuvant adjuvant radiotherapy chemotherapy targeted therapy immunotherapy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The In-Flight Realtime Trigger and Localization Software of GECAM

引用

Research in Astronomy and Astrophysics 2024年第10期24卷 11-24页

作者： xiao-yun Zhao Shao-Lin Xiong Xiang-yang wen Xin-Qiao Li Ce Cai Shuo xiao Qi Luo wen-Xi Peng Dong-Ya guo Zheng-hua An Ke Gong Jin-yuan Liao yan-Qiu zhang yue huang Lu Li Xing wen Fei zhang Jing Duan Chen-Wei wang Dong-Li Shi Peng zhang Qi-Bin Yi Chao-yang Li yan-Bing Xu xiao-hua Liang Ya-Qing Liu Da-Li zhang Xi-Lei sun Fan zhang Gang Chen huan-yu wang Sheng yang xiao-Jing Liu Min Gao Mao-Shun Li Jin-Zhou wang Xing Zhou Yi Zhao wang-Chen Xue Chao Zheng Jia-Cong Liu Xing-Bo Han Jin-Ling Qi Jia huang Ke-Ke zhang Can Chen Xiong-tao yang Dong-Jie Hou yu-Sa wang Rui Qiao Xiang Ma xiao-Bo Li ping wang Xin-Ying Song Li-Ming Song Shi-Jie Zheng Bing Li Hong-Mei zhang yue Zhu Wei Chen Jian-Jian he Zhen zhang Jin Hou Hong-Jun wang yan-Chao hao Xiang-yu wang Zong-yuan yang Zhi-Long wen Zhi Chang yuan-yuan Du Rui Gao xiao-Fei Lan yan-guo Li Gang Li Xu-fang Li fang-Jun Lu Hong Lu Bin Meng Feng Shi hui wang hui-Zhen wang yu-Peng Xu Jia-Wei yang Xue-juan yang Shuang-Nan zhang Chao-yue zhang Cheng-Mo zhang Zhi-Cheng tang Cheng Cheng Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China university of Chinese Academy of sciences Chinese Academy of SciencesBeijing 100049China School of Information science and technology Southwest Jiaotong UniversityChengdu 611756China Key Laboratory of Stellar and Interstellar Physics and Department of Physics Xiangtan UniversityXiangtan 411105China Physics and Space science college China West Normal UniversityNanchong 637002China Department of Astronomy Beijing Normal UniversityBeijing 100875China Innovation Academy for Microsatellites of CAS Shanghai 201203China Changchun university of science and technology Changchun 130022China Chinese Academy of sciences South America Center for Astronomy National Astronomical ObservatoriesCASBeijing 100101China

Realtime trigger and localization of bursts are the key functions of GECAM,an all-sky gamma-ray monitor launched on 2020 December *** developed a multifunctional trigger and localization software operating in the CPU of the GECAM Electronic *** onboard software has the following features:high trigger efficiency for real celestial bursts with a suppression of false triggers caused by charged particle bursts and background fluctuation,dedicated localization algorithm optimized for both short and long bursts,and low time latency of the trigger information which is downlinked through the Global Short Message Communication service of the global BeiDou navigation *** paper provides a detailed description of the design and development of the trigger and localization software system for *** covers the general design,workflow,the main functions,and the algorithms used in the *** paper also includes on-ground trigger tests using simulated gamma-ray bursts generated by a dedicated X-ray tube,as well as an overview of the performance for real celestial bursts during its in-orbit operation.

关键词： telescopes instrumentation:detectors methods:observational

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

CEPC Technical Design Report

引用

Radiation Detection technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai yu Bai yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci xiao-Jun Bi yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia hua Cai wenyong Cai Wujun Cai Yijian Cai Yizhou Cai yuchen Cai Haiying Cai huacheng Cai Lorenzo Calibbi Junsong Cang guofu Cao Jianshe Cao Antoine Chance Xuejun Chang yue Chang Zhe Chang Xinyuan Chang Wei Chao Auttakit Chatrabhuti Yimin Che yuzhi Che Bin Chen Danping Chen Fuqing Chen Fusan Chen Gang Chen guoming Chen hua-Xing Chen huirun Chen Jinhui Chen Ji-yuan Chen Kai Chen Mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen Xiang Chen xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen yukai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen chunhui Chen Hok Chuen Cheng huajie Cheng Shan Cheng Tongguang Cheng yunlong Chi Pietro Chimenti wen Han Chiu Guk Cho Ming-chung Chu xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui xiaohao Cui Zhaoyuan Cui Brunella D'Anzi Ling-yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi Dong Jianin AGH university of science and technology Faculty of Physics and Applied Computer ScienceKrakow Anhui university HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu university Institute of ScienceVaranasi Bandirma Onyedi Eylul university Bandirma Beihang university Beijing Beijing Computational science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research institute Co. LtdBeijing Beijing institute of technology Beijing Beijing Normal university Beijing Brown university ProvidenceRI Budker institute of Nuclear Physics Novosibirsk Cadi Ayyad university Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo university Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central China Normal university WuhanHubei Central South university ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan China academy of engineering physics MianyangSichuan China building materials academy Beijing China Center of Advanced science and technology Beijing China institute of Atomic Energy Beijing China Jiliang university HangzhouZhejiang China Nuclear Instrument CO. LTDBeijing China university of Geosciences Beijing China university of Geosciences WuhanHubei China university of Mining and technology XuzhouJiangsu China West Normal university NanchongSichuan Chongqing university Department of PhysicsChongqing Chulalongkorn university Bangkok City university of Hong Kong Department of PhysicsHong Kong Cockcroft institute Daresbury Cornell university IthacaNY CPPM(AMU/IPhu&CNRS/INP) Marseille Dalian Minzu university DalianLiaoning Dalian university of technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint institute for Nuclear Research(DLNP JINR) Dubna East China university Of science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Chinese Society of Clinical Oncology(CSCO):Clinical guidelines for the diagnosis and treatment of gastric cancer,2021

引用

Cancer Communications 2021年第8期41卷 747-795页

作者： Feng-hua wang xiao-Tian zhang yuan-fang Li Lei tang Xiu-juan Qu Jie-Er Ying Jun zhang Ling-yu sun Rong-Bo Lin Hong Qiu Chang wang Miao-Zhen Qiu Mu-yan Cai QiWu hao Liu wen-Long Guan Ai-ping Zhou yu-Jing zhang Tian-Shu Liu Feng Bi Xiang-Lin yuan Sheng-Xiang Rao yan Xin Wei-Qi Sheng hui-Mian Xu guo-Xin Li Jia-Fu Ji Zhi-Wei Zhou Han Liang yan-Qiao zhang Jing Jin Lin Shen Jin Li Rui-hua Xu Department of medical Oncology State Key Laboratory of Oncology in South ChinaCollaborative Innovation Center for Cancer MedicineSun Yat-sen University Cancer CenterGuangzhouGuangdong 510060P.R.China Department of Gastrointestinal Oncology Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education)Peking University Cancer Hospital and InstituteBeijing 100142P.R.China Department of Gastric Surgery State Key Laboratory of Oncology in South ChinaCollaborative Innovation Center for Cancer MedicineSun Yat-sen University Cancer CenterGuangzhouGuangdong 510060P.R.China Department of Radiology Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education)Peking University Cancer Hospital and InstituteBeijing 100142P.R.China Department of medical Oncology The First Hospital of China Medical UniversityShenyangLiaoning 110001P.R.China Department of medical Oncology Zhejiang Cancer HospitalHangzhouZhejiang 310006P.R.China Department of medical Oncology Ruijin HospitalShanghai Jiaotong University School of MedicineShanghai 200025P.R.China Department of Surgical Oncology The Fourth Affiliated Hospital of Harbin Medical UniversityHarbinHeilongjiang 150001P.R.China Department of medical Oncology Fujian Cancer HospitalFuzhouFujian 350000P.R.China Department of medical Oncology Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and TechnologyWuhanHubei 430030P.R.China Cancer Center of The First hospital of Jilin university ChangchunJilin 130021P.R.China Department of Pathology State Key Laboratory of Oncology in South ChinaCollaborative Innovation Center of Cancer MedicineSun Yat-sen University Cancer CenterGuangzhouGuangdong 510060P.R.China Department of Endoscopy Center Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education)Peking University Cancer Hospital and InstituteBeijing 100142P.R.China Department of General Surgery Nanfang HospitalSouthern Medical UniversityGuangzhouGuan

There exist differences in the epidemiological characteristics,clinicopathological features,tumor biological characteristics,treatment patterns,and drug selections between gastric cancer patients from the Eastern and Western *** Chinese Society of Clinical Oncology(CSCO)has organized a panel of senior experts specializing in all sub-specialties of gastric cancer to compile a clinical guideline for the diagnosis and treatment of gastric cancer since 2016 and renews it *** into account regional differences,giving full consideration to the accessibility of diagnosis and treatment resources,these experts have conducted expert consensus judgment on relevant evidence and made various grades of recommendations for the clinical diagnosis and treatment of gastric cancer to reflect the value of cancer treatment and meeting health economic indexes in *** 2021 CSCO Clinical Practice Guidelines for Gastric Cancer covers the diagnosis,treatment,follow-up,and screening of gastric *** on the 2020 version of the CSCO Chinese Gastric Cancer guidelines,this updated guideline integrates the results ofmajor clinical studies from China and overseas for the past year,focused on the inclusion of research data from the Chinese population for more personalized and clinically relevant *** the comprehensive treatment of non-metastatic gastric cancer,attentions were paid to neoadjuvant *** value of perioperative chemotherapy is gradually becoming clearer and its recommendation level has been *** the comprehensive treatment of metastatic gastric cancer,recommendations for immunotherapy were included,and immune checkpoint inhibitors fromthird-line to the first-line of treatment for different patient groups with detailed notes are provided.

关键词： adjuvant chemotherapy Chinese Society of Clinical Oncology(CSCO) diagnosis gastric cancer immunotherapy neoadjuvant radiotherapy surgery targeted therapy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus(2019-nCoV) infected pneumonia(standard version)

引用

Military medical Research 2020年第1期7卷 1-22页

作者： Ying-hui Jin Lin Cai Zhen-Shun Cheng Hong Cheng Tong Deng Yi-Pin Fan Cheng fang Di huang Lu-Qi huang Qiao huang Yong Han Bo hu Fen hu Bing-hui Li Yi-Rong Li Ke Liang Li-Kai Lin Li-Sha Luo Jing Ma Lin-Lu Ma Zhi-Yong Peng yun-Bao Pan Zhen-yu Pan Xue-Qun Ren hui-Min sun Ying wang yun-yun wang Hong weng Chao-Jie Wei Dong-fang Wu Jian Xia Yong Xiong Hai-Bo Xu xiao-Mei Yao yu-Feng yuan Tai-Sheng Ye xiao-chun zhang Ying-wen zhang Yin-Gao zhang hua-Min zhang yan Zhao Ming-juan Zhao hao Zi Xian-tao Zeng Yong-yan wang Xing-huan wang 无 Center for Evidence-Based and Translational Medicine Zhongnan Hospital of Wuhan UniversityWuhan 430071China institute of hospital Management Wuhan UniversityWuhan 430071China Department of Respiratory Medicine Zhongnan Hospital of Wuhan UniversityWuhan 430071China Department of Pharmacy Zhongnan Hospital of Wuhan UniversityWuhan 430071China institute of Evidence-Based Medicine and Knowledge Translation Henan UniversityKaifeng 475000China China Academy of Chinese medical sciences Beijing 100700China China Center for Evidence Based Traditional Chinese Medicine(CCEBTCM) Beijing 100700China Department of Critical Care Medicine Zhongnan Hospital of Wuhan UniversityWuhan 430071China Department of Clinical Laboratory Zhongnan Hospital of Wuhan UniversityWuhan 430071China Department of Infectious Diseases Zhongnan Hospital of Wuhan UniversityWuhan 430071China Division of medical Affairs Zhongnan Hospital of Wuhan UniversityWuhan 430071China Division of Nursing Affairs Zhongnan Hospital of Wuhan UniversityWuhan 430071China Office of Nosocomial Infection Control Zhongnan Hospital of Wuhan UniversityWuhan 430071China Emergency Center Zhongnan Hospital of Wuhan UniversityWuhan 430071China Department of Radiology Zhongnan Hospital of Wuhan UniversityWuhan 430071China Department of health Research Methods Evidenceand ImpactMcMaster UniversityHamiltonON L8S 4L8Canada Department of Traditional Chinese Medicine Zhongnan Hospital of Wuhan UniversityWuhan 430071China Global health institute Wuhan UniversityWuhan 430072China the Zhongnan hospital of wuhan university Novel Coronavirus Management and Research Team Evidence-Based Medicine Chapter of China International Exchange and Promotive Association for medical and health Care(CPAM)

In December 2019, a new type viral pneumonia cases occurred in wuhan, hubei Province;and then named "2019 novel coronavirus(2019-nCoV)" by the World health Organization(WHO) on 12 January 2020. For it is a never been experienced respiratory disease before and with infection ability widely and quickly, it attracted the world’s attention but without treatment and control manual. For the request from frontline clinicians and public health professionals of 2019-nCoV infected pneumonia management, an evidence-based guideline urgently needs to be developed. Therefore, we drafted this guideline according to the rapid advice guidelines methodology and general rules of WHO guideline development;we also added the first-hand management data of Zhongnan hospital of wuhan university. This guideline includes the guideline methodology, epidemiological characteristics, disease screening and population prevention, diagnosis, treatment and control(including traditional Chinese Medicine), nosocomial infection prevention and control, and disease nursing of the 2019-nCoV. Moreover, we also provide a whole process of a successful treatment case of the severe 2019-nCoV infected pneumonia and experience and lessons of hospital rescue for 2019-nCoV infections. This rapid advice guideline is suitable for the first frontline doctors and nurses, managers of hospitals and healthcare sections, community residents, public health persons, relevant researchers, and all person who are interested in the 2019-nCoV.

关键词： 2019 novel coronavirus 2019-nCoV Respiratory disease Pneumonia Infectious diseases Rapid advice guideline Clinical practice guideline Evidence-based medicine

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Data release of the LAMOST pilot survey

引用

Research in Astronomy and Astrophysics 2012年第9期12卷 1243-1246页

作者： A-Li Luo hao-Tong zhang Yong-heng Zhao Gang Zhao Xiang-Qun Cui guo-ping Li Yao-Quan Chu Jian-Rong Shi Gang wang Jian-Nan zhang Zhong-Rui Bai xiao-yan Chen Feng-Fei wang yan-Xin guo Jian-Jun Chen Bing Du xiao Kong Ya-juan Lei Yin-Bi Li Yi-Han Song yue Wu yan-Xia zhang Xin-Lin Zhou fang Zuo Peng Du Lin he wen Hou Yi-Qiao Dong Jian Li Guang-Wei Li Shuang Li Jing Song yuan Tian Meng-Xin wang Yong-hui Hou Zhi-Ying huo Hong-Zhuan hu Ning-Sheng hu Zhong-wen hu Lei Jia fang-hua Jiang Xiang Jiang Zi-Bo Jiang Ge Jin Ai-hua Li Qi Li Yin-Dun Mao Zheng-Hong tang Qing-Sheng tao Liang-ping Tu Da-Qing wang Dan wang Jian-ping wang Lei wang Shou-Guan wang Shu-Qing wang Ya-Nan wang You wang yue-Fei wang Ming-Zhi Wei Xiang-Xiang Xue xiao-Zheng Xing Ling-Zhe Xu Xin-Qi Xu yan Xu De-hua yang Shi-Hai yang Zheng-Qiu Yao Yong yu hui yuan Chao Zhai En-Peng zhang Jing zhang Li-ping zhang Weizhang Yong zhang Zhen-Chao zhang Ming Zhao fang Zhou Yong-Tian Zhu Jie Zhu Si-Cheng Zou National Astronomical Observatories Chinese Academy of Sciences Beijing 100012 China lal @ lamost o rg Nanjing institute of Astronomical Optics and technology National Astronomical ObservatoriesChinese Academy of Sciences Nanjing 210042 China university of science and technologyof China Hefei 230026 China Shanghai Astronomical Observatory Chinese Academy of Sciences Shanghai 200030 China institute of Architecture Design and Research Chinese Academy of Sciences Beijing 100190China

This paper describes the data release of the LAMOST pilot survey, which includes data reduction, calibration, spectral analysis, data products and data access. The accuracy of the released data and the information about the FITS headers of spectra are also introduced. The released data set includes 319 000 spectra and a catalog of these objects.

关键词： techniques: spectroscopic survey — data reduction — data release

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Precision Surgery for Placenta Previa Complicated with Placenta Percreta

引用

Maternal-Fetal Medicine 2019年第1期1卷 18-24页

作者： juan-juan Chen Lin yu chun-Hong Su chun-fang zhang yan-Hong Chen yan-Mei Zhou wen-Jun he fang he Ting Song Shou-ping wang Zhi-yuan Su Qing-ping Jiang Zi-hao Zou Bin yu xiao-Ya Shen xiao-Ming Guan Dun-Jin Chen Key Laboratory for Major Obstetric Diseases of Guangdong Province Department of Gynaecology andObstetricsThird Affiliated Hospital of Guangzhou Medical UniversityGuangzhouGuangdong510150China Department of Radiology Third Affiliated Hospital of Guangzhou Medical UniversityGuangzhouGuangdong 510150China Department of Anesthesiology Third Affiliated Hospital ofGuangzhou Medical UniversityGuangzhouGuangdong 510150China Department of Pathology ThirdAffiliated Hospital of Guangzhou Medical UniversityGuangzhouGuangdong510150China Department of Urology Third Affiliated Hospital of Guangzhou Medical UniversityGuangzhouGuangdong 510150China Department of Obstetrics&Gynecology Baylor College ofMedicineHoustonUSA

Objectives:To investigate whether a precise circular resection of the uterine tissue at the placental attachment part is effective in cases with placenta previa complicated with placenta percreta (PPWPP).Methods:Patients diagnosed with PPWPP were assessed for pregnancy termination at 34-36 weeks of *** the operation,we performed circular resection of the uterine tissue at the placental attachment *** the characteristics of the operation and the follow-ups were ***:During the operation,the vital signs were *** mean intraoperative blood loss,packed red blood cells units transfusion,fresh frozen plasma transfusion,and operation time were 2140 mL,6 U,440 mL,and 179.8 minutes,*** was no bowel,ureter,or bladder *** there was no patient transferred to the ICU after *** mean postoperative blood loss was *** was no fever,infection,intestinal obstruction,or other complications after operation during the *** shape and the blood flow of the uterus were *** the patients were discharged,one had developed cesarean scar *** mean lochia duration was 30 *** menstrual cycle and volume were as *** shape and the blood flow of the uterus and the ovarian were ***:The circular resection following end-to-end anastomosis is an effective precision surgical approach for *** can achieve the purpose of hemostasis while maximizing the protection of organ function and reducing surgical trauma.

关键词： Placenta previa Placenta percreta Precision surgery Circular resection

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

2015—2021年CHINET临床分离葡萄球菌属细菌耐药性变迁

引用

中国感染与化疗杂志 2024年第5期24卷 570-580页

作者：肖玉玲康梅谢轶杨洋胡付品朱德妹徐英春张小江季萍张峰波王传清付盼徐元宏黄颖孙自镛陈中举倪语星孙景勇褚云卓田素飞胡志东李金俞云松林洁单斌杜艳郭素芳魏莲花邹凤梅张泓王春胡云建艾效曼卓超苏丹虹郭大文赵金英喻华黄湘宁刘文恩李艳明金炎邵春红徐雪松鄢超王山梅楚亚菲张利侠马娟周树平周艳朱镭孟晋华董方吕志勇胡芳芳沈瀚周万青贾伟李刚吴劲松卢月梅李继红段金菊康建邦马晓波郑燕萍郭如意朱焱陈运生孟青王世富胡雪飞沈继录黄文辉汪瑞忠房华俞碧霞赵勇龚萍温开镇张贻荣刘江山廖龙凤顾洪芹姜琳贺雯薛顺虹冯佼岳春雷四川大学华西医院实验医学科成都610041 复旦大学附属华山医院抗生素研究所北京协和医院新疆医科大学第一附属医院复旦大学附属儿科医院安徽医科大学第一附属医院华中科技大学同济医学院附属同济医院上海交通大学医学院附属瑞金医院中国医科大学附属第一医院天津医科大学总医院浙江大学医学院附属邵逸夫医院昆明医科大学第一附属医院内蒙古医科大学附属医院甘肃省人民医院上海交通大学医学院附属儿童医院北京医院广州医科大学附属第一医院哈尔滨医科大学附属第一医院四川省人民医院中南大学湘雅医院山东省立医院吉林大学中日联谊医院河南省人民医院陕西省人民医院江西省儿童医院山西省儿童医院首都医科大学附属北京儿童医院贵州省人民医院南京大学医学院附属鼓楼医院宁夏医科大学总医院深圳市人民医院河北医科大学第二医院山西医科大学第二医院厦门大学附属第一医院福建省泉州市第一医院深圳市儿童医院山东大学齐鲁儿童医院南昌大学第一附属医院安徽医科大学第四附属医院青海大学附属医院上海市浦东新区人民医院浙江省宁波市镇海龙赛医院湖北省秭归县人民医院福建省晋江市医院甘肃省金昌市中西医结合医院江西省赣县区人民医院山东省广饶县人民医院河南省辉县市人民医院辽宁省营口市经济技术开发区中心医院青海省互助县人民医院四川省邻水县人民医院吉林省九台区人民医院

目的了解2015-2021年中国不同地区临床分离葡萄球菌属细菌的分布及耐药变迁。方法按CHINET中国细菌耐药监测网统一的技术方案对临床分离的葡萄球菌采用纸片法和商品化药敏试验测试仪(机器法)进行药物敏感性试验;收集2015-2021年CHINET... 详细信息

目的了解2015-2021年中国不同地区临床分离葡萄球菌属细菌的分布及耐药变迁。方法按CHINET中国细菌耐药监测网统一的技术方案对临床分离的葡萄球菌采用纸片法和商品化药敏试验测试仪(机器法)进行药物敏感性试验;收集2015-2021年CHINET的葡萄球菌耐药监测数据,使用WHONET 5.6软件统计并按2021年CLSI折点标准判读结果。结果2015-2021年共分离非重复葡萄球菌属细菌204771株,其中金黄色葡萄球菌136731株(66.8%),凝固酶阴性葡萄球菌68040株(33.2%),7年间两者检出率均无明显变化。金黄色葡萄球菌主要分离自呼吸道标本(38.9±5.1)%、伤口脓液分泌物(33.6±4.2)%、血液(11.9±1.5)%;凝固酶阴性葡萄球菌主要分离自血液(73.6±4.2)%、脑脊液(12.1±2.5)%、胸腹水(8.4±2.1)%。金黄色葡萄球菌的科室来源主要为ICU(17.0±7.3)%、门急诊(11.6±1.7)%、外科(11.2±0.9)%;凝固酶阴性葡萄球菌的科室来源主要为ICU(32.2±9.7)%、门急诊(12.8±4.7)%、内科(11.2±1.9)%。金黄色葡萄球菌、凝固酶阴性葡萄球菌中甲氧西林耐药株的总体检出率分别为32.9%、74.1%,7年间MRSA检出率从42.1%下降至29.2%,MRCNS检出率从82.1%下降至68.2%。除甲氧苄啶-磺胺甲噁唑外,MRSA对各类抗菌药物的耐药率均高于MSSA。MRSA对庆大霉素、利福平、左氧氟沙星耐药率有所下降;MRCNS对庆大霉素、红霉素、利福平、甲氧苄啶-磺胺甲噁唑的耐药率有所下降,对左氧氟沙星的耐药率有所上升。未发现对万古霉素耐药的葡萄球菌菌株。对利奈唑胺耐药的MRCNS有所增多,7年间耐药率从0.2%上升至2.3%。结论葡萄球菌属细菌仍是革兰阳性菌中最主要的细菌。MRSA和MRCNS亦仍然是革兰阳性菌中最主要的耐药细菌。至今未发现对万古霉素和利奈唑胺耐药的金黄色葡萄球菌,但已有利奈唑胺耐药的MRCNS菌株检出,应加强监测和关注。

关键词：葡萄球菌细菌耐药性监测抗菌药物药敏试验

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：