检索结果-南通市图书馆

CaH2-promoted activity of Ni-carbonate interface for CO2 methanation

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2025年第1期100卷 522-532页

作者： Jin-Peng wang Guo-Cui Mao Hui-Lin Jiang Bao-Xia dong Yun-Lei Teng School of Chemistry and Chemical Engineering Yangzhou University

Transition metal-carbonate interfaces often act as active sites in heterogeneous catalytic *** interface between transition metal and metal carbonate exhibits a dynamic equilibrium during the CO2hydrogenation reaction,involving surface carbonate hydrogenation and ***,there have been few reports on engineering the activity of the interface between transition metal and alkaline earth metal carbonate for catalytic *** work demonstrated that the incorporation of CaH2in Ni/CaCO3enhances the CO2methanation activity of the *** CO2conversion for Ni/CaH2-CaCO3reached 68.5%at 400°C,which was much higher than that of the Ni/CaCO3（31.6%） and Ni/CaH2-CaO （42.4%） ***,the Ni/CaH2-CaCO3catalysts remained stable during the stability test for 24 h at 400°C and 8 *** research revealed that CaH2played a crucial role in promoting the activity of the Ni-carbonate interface for ***2could modify the electronic structure of Ni and tune the structural properties of CaCO3to generate medium basic sites （OH groups）,which are favorable for the activation of H2and ***-situ Fourier transform infrared spectroscopy （FTIR） analysis combined with density functional theory calculations demonstrated that CO2activation occurs at the hydroxyl group （OH） on the CaH2-modified Ni-carbonate surface,leading to the formation of CO3H****,our study has confirmed that CO2methanation over the Ni/CaH2-CaCO3catalysts proceeds via the formate pathway.

关键词： Metal hydride Ni catalysts Carbonate Metal-carbonate interface

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

FCC澄清油炭化产物电流变液的特性研究

石油化工 2001年第6期30卷 460-463页

作者：王春慧董鹏孙志伟石油大学(北京)重质油加工国家重点实验室北京102200

考察了四种FCC澄清油炭化产物电流变液的电流变特性 ,研究了炭化深度对电流变特性的影响 ,比较FCC澄清油炭化产物电流变液与渣油炭化产物电流变液的电流变特性。结果表明 :FCC澄清油炭化产物电流变液具有很好的电流变特性 ,可作为一种... 详细信息

考察了四种FCC澄清油炭化产物电流变液的电流变特性 ,研究了炭化深度对电流变特性的影响 ,比较FCC澄清油炭化产物电流变液与渣油炭化产物电流变液的电流变特性。结果表明 :FCC澄清油炭化产物电流变液具有很好的电流变特性 ,可作为一种高性能电流变液 ,其流变曲线可用Bingham模型描述 ;FCC澄清油炭化产物电流变液与中间相沥青及碳纤维前体炭化产物电流变液一样 ,都存在一最佳C/H原子比 ;FCC澄清油炭化产物电流变液的电流变特性优于渣油炭化产物电流变液的电流变特性 ,并对试验结果进行了讨论。

关键词： FCC澄清油电流变效应电流变液炭化智能材料

Human neural stem cell-derived extracellular vesicles protect against ischemic stroke by activating the PI3K/AKT/mTOR pathway

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第11期20卷 3245-3258页

作者： Jiayi wang Mengke Zhao dong Fu Meina wang Chao Han Zhongyue Lv Liang wang Jing Liu Stem Cell Clinical Research Center The First Affiliated Hospital of Dalian Medical UniversityDalianLiaoning ProvinceChina Dalian Innovation Institute of Stem Cell and Precision Medicine DalianLiaoning ProvinceChina Institute(College)of Integrative Medicine Dalian Medical UniversityDalianLiaoning ProvinceChina

Human neural stem cell-derived extracellular vesicles exhibit analogous functions to their parental cells,and can thus be used as substitutes for stem cells in stem cell therapy,thereby mitigating the risks of stem cell therapy and advancing the frontiers of stem cell-derived *** lays a foundation for the development of potentially potent new treatment modalities for ischemic ***,the precise mechanisms underlying the efficacy and safety of human neural stem cell-derived extracellular vesicles remain unclear,presenting challenges for clinical *** promote the translation of therapy based on human neural stem cell-derived extracellular vesicles from the bench to the bedside,we conducted a comprehensive preclinical study to evaluate the efficacy and safety of human neural stem cell-derived extracellular vesicles in the treatment of ischemic *** found that administration of human neural stem cell-derived extracellular vesicles to an ischemic stroke rat model reduced the volume of cerebral infarction and promoted functional recovery by alleviating neuronal *** human neural stem cell-derived extracellular vesicles reduced neuronal apoptosis by enhancing phosphorylation of phosphoinositide 3-kinase,mammalian target of rapamycin,and protein kinase B,and these effects were reversed by treatment with a phosphoinositide 3-kinase *** findings suggest that human neural stem cell-derived extracellular vesicles play a neuroprotective role in ischemic stroke through activation of phosphoinositide 3-kinase/protein kinase B/mammalian target of rapamycin signaling ***,we showed that human neural stem cell-derived extracellular vesicles have a good in vivo safety ***,human neural stem cell-derived extracellular vesicles are a promising potential agent for the treatment of ischemic stroke.

关键词： behavior exosome extracellular vesicles ischemic stroke mammalian target of rapamycin(mTOR) middle cerebral artery occlusion neural stem cells neuronal apoptosis phosphoinositide 3-kinase(PI3K) protein kinase B(AKT)

Single-cell omics: experimental workflow, data analyses and applications

在线全文

学校读者我要写书评

暂无评论

Science China Life Sciences 2025年第1期68卷 5-102页

作者： Fengying Sun Haoyan Li dongqing Sun Shaliu Fu Lei Gu Xin Shao Qinqin wang Xin dong Bin Duan Feiyang Xing Jun Wu Minmin Xiao Fangqing Zhao Jing-dong J.Han Qi Liu Xiaohui Fan Chen Li Chenfei wang Tieliu Shi Department of Clinical Laboratory the Affiliated Wuhu Hospital of East China Normal University (The Second People's Hospital of Wuhu City) Pharmaceutical Informatics Institute College of Pharmaceutical SciencesZhejiang University Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration (Tongji University) Ministry of EducationOrthopaedic DepartmentTongji HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji University Frontier Science Center for Stem Cells School of Life Sciences and TechnologyTongji University Translational Medical Center for Stem Cell Therapy and Institute for Regenerative Medicine Shanghai East HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji University Research Institute of Intelligent Computing Zhejiang Lab Shanghai Research Institute for Intelligent Autonomous Systems Center for Single-cell Omics School of Public HealthShanghai Jiao Tong University School of Medicine National Key Laboratory of Chinese Medicine Modernization Innovation Center of Yangtze River DeltaZhejiang University Center for Bioinformatics and Computational Biology Shanghai Key Laboratory of Regulatory Biologythe Institute of Biomedical Sciences and School of Life SciencesEast China Normal University Beijing Institutes of Life Science Chinese Academy of Sciences Peking-Tsinghua Center for Life Sciences Academy for Advanced Interdisciplinary StudiesCenter for Quantitative Biology (CQB)Peking University Zhejiang Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases Women's HospitalZhejiang University School of Medicine Key Laboratory of Advanced Theory and Application in Statistics and Data Science-MOE School of StatisticsEast China Normal University

Cells are the fundamental units of biological systems and exhibit unique development trajectories and molecular features. Our exploration of how the genomes orchestrate the formation and maintenance of each cell, and control the cellular phenotypes of various organismsis, is both captivating and intricate. Since the inception of the first single-cell RNA technology, technologies related to single-cell sequencing have experienced rapid advancements in recent years. These technologies have expanded horizontally to include single-cell genome, epigenome,proteome, and metabolome, while vertically, they have progressed to integrate multiple omics data and incorporate additional information such as spatial sc RNA-seq and CRISPR screening. Single-cell omics represent a groundbreaking advancement in the biomedical field,offering profound insights into the understanding of complex diseases, including cancers. Here, we comprehensively summarize recent advances in single-cell omics technologies, with a specific focus on the methodology section. This overview aims to guide researchers in selecting appropriate methods for single-cell sequencing and related data analysis.

关键词： single-cell sequencing genome epigenome proteomics metabolomics multimodal spatial transcriptomics CRISPR screening

阿芬太尼复合丙泊酚用于老年患者无痛胃镜检查的临床研究

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

中国临床药理学杂志 2023年第15期39卷 2174-2178页

作者：李航王春东莫云长温州医科大学附属东阳医院、东阳市人民医院麻醉科浙江东阳322100 温州医科大学附属第一医院麻醉科浙江温州322100

目的观察不同剂量阿芬太尼注射液复合丙泊酚注射液用于老年无痛胃镜检查患者的临床效果及安全性。方法将拟进行无痛胃镜检查老年患者用随机数字表分为低、中和高剂量组。低剂量组给予5μg·kg^(-1)阿芬太尼和2 mg·kg^(-1)丙泊酚,中剂... 详细信息

目的观察不同剂量阿芬太尼注射液复合丙泊酚注射液用于老年无痛胃镜检查患者的临床效果及安全性。方法将拟进行无痛胃镜检查老年患者用随机数字表分为低、中和高剂量组。低剂量组给予5μg·kg^(-1)阿芬太尼和2 mg·kg^(-1)丙泊酚,中剂量组给予7μg·kg^(-1)阿芬太尼和2 mg·kg^(-1)丙泊酚,高剂量组给予9μg·kg^(-1)阿芬太尼和2 mg·kg^(-1)丙泊酚。比较3组患者的麻醉和苏醒情况、生命体征以及药物不良反应发生率。结果低、中和高剂量组各纳入26例。低、中和高剂量组的丙泊酚追加例数分别为10例(38.46%)、4例(15.38%)和1例(3.85%),丙泊酚用量分别为(126.37±19.56)、(104.68±15.74)和(102.49±14.82)mg,检查时间分别为(8.91±1.63)、(8.03±1.45)和(7.86±1.38)min,睁眼时间分别为(2.35±0.72)、(1.86±0.51)和(1.57±0.45)min,离院时间分别为(16.43±3.19)、(14.70±2.68)和(14.26±2.53)min,中、高剂量组的上述指标与低剂量组比较,差异均有统计学意义(均P<0.05)。与给药前1 min(T_(0))相比,低剂量组进镜至咽喉(T_(1))、进镜至十二指肠(T_(2))和检查结束(T_(3))时的心率(HR)和平均动脉压(MAP)均明显降低(均P<0.05),中、高剂量组T_(1)、T_(2)、T_(3)时的MAP均明显降低(均P<0.05);且与低剂量组相比,中、高剂量组T_(1)、T_(2)、T_(3)时的MAP降低幅度均明显减小(均P<0.05)。与检查前相比,3组检查后血清超氧化物歧化酶(SOD)活性均显著降低(均P<0.05),血清皮质醇(Cor)和去甲肾上腺素(NE)水平均显著升高(均P<0.05),且与低剂量组相比,中、高剂量组的SOD活性降低幅度均明显减小,MDA和NE水平升高幅度均明显减小(均P<0.05)。结论老年人群胃镜检查采用阿芬太尼复合丙泊酚麻醉具有良好镇痛效果和安全性,有利于减少丙泊酚用药剂量,阿芬太尼剂量为7μg·kg^(-1)时氧化应激水平和药物不良反应发生率较低,在安全性方面具有明显优势。

关键词：阿芬太尼注射液丙泊酚注射液无痛胃镜老年镇痛

用Cisco路由器实现校园网中基于数据包过滤的安全管理机制

在线全文

学校读者我要写书评

暂无评论

天津理工学院学报 2000年第3期16卷 69-72页

作者：王春东天津理工学院信息技术中心天津300191

介绍了因特网上防火墙技术中的数据包过滤技术的原理 ,讨论了校园网上基于包过滤的安全原则的设计。

关键词：数据包过滤 Cisco路由器安全管理校园网

在线全文

学校读者我要写书评

暂无评论

Internet网络安全策略与技术的研究

天津职业技术师范学院学报 2000年第1期10卷 25-28,34页

作者：王春东天津理工学院天津300191

因特网在我们生活中日益普及 ,安全问题也日渐突出。本文围绕网络安全问题介绍了因特网常见的侵袭 ,阐明了网络安全策略 ,分析了主要的网络安全技术 ,包括防火墙和数据加密等。提出了构筑网络安全的建议。

关键词：因特网安全侵袭防火墙数据包过滤代理服务数据加密

Efficient and simple synthesis of B_(2)O_(3)-Al_(2)O_(3)nanocomposites assisted by deep eutectic solvent for production of 5-hydroxymethylfurfural from glucose

在线全文

学校读者我要写书评

暂无评论

Nano Research 2025年第1期18卷 236-248页

作者： Yuchen wang Kai Rong Shanlei Chang Youxing Fang Shaojun dong State Key Laboratory of Electroanalytical Chemistry Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China School of Applied Chemistry and Engineering University of Science and Technology of ChinaHefei 230026China College of Chemistry Jilin UniversityChangchun 130012China

The catalytic conversion of glucose to high valueadded platform chemical 5-hydroxymethylfurfural(HMF)is a promising biorefinery process,and alumina-boria catalysts are considered to be green and mild solid acid catalysts for this catalytic ***,compared to the common synthesis methods with complicated steps,we reported a simple and efficient strategy to prepare B_(2)O_(3)-Al_(2)O_(3)nanocomposites by calcining cost-effective glucose-urea deep eutectic solvent(DES)solution containing the *** prepared B_(2)O_(3)-Al_(2)O_(3)nanocomposites exhibited an open three-dimensional skeleton and two-dimensional porous lamellar substructure,endowing them with a high specific surface area(228.27 m2/g).The introduction of boron changed the ratios of different aluminum species(AlⅣ,AlⅤ,and AlⅥ)and borate species(BO3 and BO4),thus further affecting the acidity and the types of acid sites of the *** prepared B_(2)O_(3)-Al_(2)O_(3)bifunctional acid catalysts possessing abundant Lewis acid sites and adjustable Brønsted acid sites showed complete glucose conversion and 55.38%of HMF yield under the optimum *** study proposed a concise method to synthesize alumina-boria solid acid catalysts assisted by glucose-urea *** hope to extend the application and prospect of this efficient and simple synthesis strategy.

关键词： 5-hydroxymethylfurfural(HMF) deep eutectic solvent glucose alumina-boria acid catalyst

壁面加热边界条件对湍流扩展的自相似性的影响

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

实验力学 2001年第3期16卷 256-263页

作者：姜楠王玉春王振东舒玮天津大学力学系天津300072

用热线风速仪测量了风洞中壁面加热和不加热平板湍流边界层不同法向位置的瞬时流向速度的时间序列 ,研究了壁面加热的边界条件对流向速度增量的 p阶结构函数的扩展的自相似性和层次结构模型的影响 .实验结果表明 ,壁面加热的边界条件对... 详细信息

用热线风速仪测量了风洞中壁面加热和不加热平板湍流边界层不同法向位置的瞬时流向速度的时间序列 ,研究了壁面加热的边界条件对流向速度增量的 p阶结构函数的扩展的自相似性和层次结构模型的影响 .实验结果表明 ,壁面加热的边界条件对流向速度增量的结构函数扩展的自相似标度律的相对标度指数ζ( p,3 )和层次结构模型中间歇参数 β、最奇异指数 γ的影响明显存在 .

关键词：加热壁湍流扩展自相似性层次结构模型