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Gut microbial diversity analysis using Illumina sequencing for functional dyspepsia with liver depression-spleen deficiency syndrome and the interventional Xiaoyaosan in a rat model

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World Journal of Gastroenterology 2017年第5期23卷 810-816页

作者： juan-juan Qiu Zhe Liu Peng Zhao xue-Jun Wang Yu-chun Li Hua Sui Lawrence Owusu Hui-Shu Guo Zheng-xu Cai Central Laboratory The First Affiliated Hospital of Dalian Medical University Department of Neurology The First Affiliated Hospital of Dalian Medical University Academy of Integrative Medicine Dalian Medical University

AIM To investigate gut microbial diversity and the interventional effect of Xiaoyaosan(XYS) in a rat model of functional dyspepsia(FD) with liver depression-spleen deficiency syndrome. METHODS The FD with liver depression-spleen deficiency syndrome rat model was established through classic chronic mild unpredictable stimulation every day. XYS group rats received XYS 1 h before the stimulation. The models were assessed by parameters including state ofthe rat, weight, sucrose test result and open-field test result. After 3 wk, the stools of rats were collected and genomic DNA was extracted. PCR products of the V4 region of 16 S rD NA were sequenced using a barcoded Illumina paired-end sequencing technique. The primary composition of the microbiome in the stool samples was determined and analyzed by cluster *** Rat models were successfully established, per data from rat state, weight and open-field test. The microbiomes contained 20 phyla from all samples. Firmicutes, Bacteroidetes, Proteobacteria, Cyanobacteria and Tenericutes were the most abundant taxonomic groups. The relative abundance of Firmicutes, Proteobacteria and Cyanobacteria in the model group was higher than that in the normal group. On the contrary, the relative abundance of Bacteroidetes in the model group was lower than that in the normal group. Upon XYS treatment, the relative abundance of all dysregulated phyla was restored to levels similar to those observed in the normal group. Abundance clustering heat map of phyla corroborated the taxonomic distribution. CONCLUSION The microbiome relative abundance of FD rats with liver depression-spleen deficiency syndrome was significantly different from the normal cohort. XYS intervention may effectively adjust the gut dysbacteriosis in FD.

关键词： Functional dyspepsia with liver depression-spleen deficiency syndrome Illumina sequencing Gut microbial diversity Xiaoyaosan

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Chromosome-level genome assembly of the freshwater snail Bellamya purificata(Caenogastropoda)

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Zoological Research 2022年第4期43卷 683-686页

作者： Wu Jin Xiao-juan Cao xue-Yan Ma Guo-Hua Lv Gang-chun xu Pao xu Bing Sun Dong-Po xu Hai-Bo Wen Key Laboratory of Integrated Rice-Fish Farming Ecology Ministry of Agriculture and Rural AffairsFreshwater Fisheries Research CenterChinese Academy of Fishery SciencesWuxiJiangsu 214081China Wuxi Fisheries College Nanjing Agricultural UniversityWuxiJiangsu 214128China College of Fisheries Engineering Research Center of Green Development for Conventional Aquatic Biological Industry in the Yangtze River Economic BeltMinistry of EducationHuazhong Agricultural UniversityWuhanHubei 430070China

DEAR EDITOR,Bellamya purificata(Gastropoda:Caenogastropoda;Architaenioglossa;Viviparidae:Bellamyinae;Sinotaia),a homotypic synonym of ***,is widely distributed in freshwater habitats in *** is an economically important edible snail and plays a vital function in freshwater wetland ***,genomic resources for this snail are lacking and no reference genome has been *** this study,we constructed the first chromosome-level genome of *** using PacBio long-read sequencing and high-throughput chromosome conformation capture(Hi-C)technology.

关键词： freshwater snail habitat

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Long-term Visual Tracking: Review and Experimental Comparison

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Machine Intelligence Research 2022年第6期19卷 512-530页

作者： Chang Liu Xiao-Fan Chen chun-juan Bo Dong Wang School of Information and Communication Engineering Dalian University of TechnologyDalian 116024China Dalian Minzu University Dalian 116600China

As a fundamental task in computer vision,visual object tracking has received much attention in recent *** studies focus on short-term visual tracking which addresses shorter videos and always-visible ***,long-term visual tracking is much closer to practical applications with more complicated *** exists a longer duration such as minute-level or even hour-level in the long-term tracking task,and the task also needs to handle more frequent target disappearance and *** this paper,we provide a thorough review of long-term tracking,summarizing long-term tracking algorithms from two perspectives:framework architectures and utilization of intermediate tracking *** we provide a detailed description of existing benchmarks and corresponding evaluation ***,we conduct extensive experiments and analyse the performance of trackers on six benchmarks:VOTLT2018,VOTLT2019(2020/2021),OxuvA,LaSOT,TLP and the long-term subset of ***,we discuss the future prospects from multiple perspectives,including algorithm design and benchmark *** our knowledge,this is the first comprehensive survey for long-term visual object *** relevant content is available at https://***/wangdongdut/Long-term-Visual-Tracking.

关键词： Visual object tracking long-term tracking short-term tracking re-detection online update

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Transverse mode-coupling instability with longitudinal impedance

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Nuclear Science and Techniques 2024年第6期35卷 40-53页

作者： Hai-Sheng xu chun-Tao Lin Na Wang Jing-Ye xu Yuan Zhang Key Laboratory of Particle Acceleration Physics and Technology Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China Institute of Advanced Science Facilities Shenzhen 518107GuangdongChina

Transverse mode-coupling instability(TMCI)is a dangerous transverse single-bunch instability that can lead to severe par-ticle *** mechanism of TMCI can be explained by the coupling of transverse coherent oscillation modes owing to the transverse short-range wakefield(i.e.,the transverse broadband impedance).Recent studies on future circular colliders,e.g.,FCC-ee,showed that the threshold of TMCI decreased significantly when both longitudinal and transverse impedances were *** performed computations for the circular electron-positron collider(CEPC)and observed a similar *** studies on the influence of longitudinal impedance on the TMCI threshold were *** concluded that the imaginary part of the longitudinal impedance,which caused a reduction in the incoherent synchrotron tune,was the primary reason for the reduction in the TMCI ***,the real part of the longitudinal impedance assists in increasing the TMCI threshold.

关键词： Transverse mode-coupling instability Longitudinal impedance

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The Diterpenoid Quinones from Coleus forskohlii

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Chinese Chemical Letters 2001年第4期12卷 339-342页

作者： chun Suo YAO Yun Long xu Laboratory of Phytochemistry Kunming Institute of BotanyAcademia SinicaKunming 650204

Two new diterpenoid quinones, colean S and T were isolated from the chloroform extract of the leaves of Coleus forskohlii, and based on spectroscopic data, their structures were identified as 1,4-phananthrenedione-4b,... 详细信息

关键词： Coleus forskohlii diterpenoid quinones Coleon S Coleon T.

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An Approach to New Water-soluble Oligo(ethylene glycol) Camptothecin Analogues by 1,3-Dipolar Cycloaddition

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Chinese Chemical Letters 2006年第7期17卷 883-886页

作者： chun Yan xu Ming Zhi HUANG College of Materials Science and Technology Beijing University of Chemical Technology Beijing 100029

Combined with an effective copper-catalyzed triazole-forming reaction, a series of novel camptothecin derivatives were synthesized. Incorporating oligo（ethylene glycol） chains into the derivatives enhanced their wat... 详细信息

关键词： Click chemistry 20(S)-camptothecin water-soluble derivatives.

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Context Processing in Contextual and Cued Fear Extinction

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Neuroscience Bulletin 2024年第6期40卷 835-839页

作者： Yimu Zhang chun xu Yu Gu State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science Institutes of Brain ScienceFudan UniversityShanghai200032China Institute of Neuroscience State Key Laboratory of NeuroscienceCenter for Excellence in Brain Science and Intelligence TechnologyChinese Academy of SciencesShanghai200031China

Anxiety disorders such as post-traumatic stress disorder(PTSD)are prevalent mental disorders that disturb millions *** disorders often manifest as excessive fear,anxiety,and distress,significantly impacting daily *** fear extinction paradigms in animals were established decades ago and have been widely used in research,providing a scientific basis for exposure therapies for anxiety disorders in humans.

关键词： distress disorders traumatic

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High Glass Transition of Fluorinated Polyimides Derived from 4-（3,4-Difluorophenyl）-2,6-bis（4-aminophenyl）pyridine

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Chinese Journal of Chemistry 2017年第3期35卷 341-346页

作者： xu xu Beicai Chen Hua Li Xiaohua Huang chun Wei Key Laboratory of New Processing Technology for NonJerrous Metal & Materials Ministry of Education andSchool of Material Science and Engineering Guilin University of Technology Guilin Guangxi 541004 China Department of Mechanical Automotive & Materials Engineering University of Windsor 401 Sunset Ave Windsor ON Canada N9B 3P4

A series of novel fluorinated polyimides (PIs) were prepared from 4-(3,4-difluorophenyl)-2,6-bis(4-aminophenyl)pyridine (FPAP) and commercial aromatic dianhydrides via conventional two-step thermal imidization technique. The structure of the monomer was confirmed by FT-IR, NMR, and mass spectrometry. All of the obtained PIs were studied with FT-IR, TGA, DSC, WAXD and contact angles analysis. These results showed that polymer materials presented excellent thermal properties with the glass transition temperature (Tg) in the range of 336—434 °C, as well as T5%, and T10% decomposition temperature ranges of 543—600 °C and 562—622 °C in a nitrogen atmosphere, respectively. Moreover, they presented excellent mechanical properties with tensile strengths of 68—91 MPa, elongation at break of 5.6%—10.2%, and young’s modulus of 1.8—2.4 GPa. Furthermore, they showed outstanding hydrophobicity with the contact angle in the range of 90.5°—96.6°, and the results of WAXD indicated all of the polymers presented amorphous structure.

关键词： fluorinated polyimides thermal properties pyridine hydrophobicity

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Flow Behavior and Numerical Simulation of Spray-Formed FGH95 Superalloy Under Hot Compression

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Journal of Iron and Steel Research International 2013年第12期20卷 69-74页

作者： GUO Biao GE Chang-chun xu Yi School of Materials Science and Engineering Southwest Jiaotong University Institute of Special Ceramics and Powder Metallurgy School of Materials Science and Engineering University of Science and Technology Beijing

The flow behavior of spray-formed FGH95 superalloy （similar to Rene 95） was investigated at tempera- tures ranging from 1050 to 1 140 ℃ and strain rate ranging from 0.01 to 10 s-1. At a given temperature and strain rate, flow stress increases quickly with increasing strain and then reaches a peak, then gradual decreases until high strain, and dynamic softening is observed. Utilizing the hyperbolic sine {unction and introducing the strain with non- linear fitting, the revised constitutive equations incorporating the effects of temperature, strain rate and strain for high temperature flow stress prediction of superalloy were established. The revised constitutive equations were im- planted into finite element software by second development to simulate the hot compression process successfully, and the effective stress and load stroke curves obtained by numerical simulation are good agreement with the experimen- tal results.

关键词： spray-formed FGH95 superalloy constitutive equations numerical simulation

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Highly flexible,foldable,and rollable microsupercapacitors on an ultrathin polyimide substrate with high power density

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Microsystems & Nanoengineering 2018年第1期4卷 223-233页

作者： juan Pu Xiaohong Wang Renxiao xu Sixing xu Kyriakos Komvopoulos Department of Microelectronics and Nanoelectronics Tsinghua UniversityBeijing 100084China Institute of Microelectronics Tsinghua UniversityBeijing 100084China Tsinghua National Laboratory for Information Science and Technology Beijing 100084China Department of Mechanical Engineering University of CaliforniaBerkeleyCA 94720USA

The design and functionality of extremely flexible,foldable,and rollable microsupercapacitors(MSCs)with in-plane interdigital electrodes that consist of single-walled carbon nanotube(SWCNT)networks on an ultrathin polyimide substrate are demonstrated through experiments and finite element *** all-solid-state MSCs can be reversibly bent,folded,and rolled purely elastically without degradation of their electrical *** simulation results confirm that the deformation in bent,folded,and rolled MSCs is purely *** high power density(1125W cm^(–3))and small time constant(1 ms)of the present MSCs are comparable to those of aluminum electrolytic *** MSCs operate at scan rates of up to 1000 V s^(–1),are characterized by a volumetric capacitance of 18 F cm^(–3) and an energy density of 1.6 mWh cm^(–3),and exhibit superior electrochemical stability with 96% capacity retention even after 100,000 charge/discharge *** developed MSCs demonstrate high potential for integration in flexible and wearable electronic systems.

关键词： purely Highly power

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